Download or read book Data Analysis for Neurodegenerative Disorders written by Deepika Koundal and published by Springer Nature. This book was released on 2023-05-31 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the challenges involved in handling medical big data in the diagnosis of neurological disorders. It discusses how to optimally reduce the number of neuropsychological tests during the classification of these disorders by using feature selection methods based on the diagnostic information of enrolled subjects. The book includes key definitions/models and covers their applications in different types of signal/image processing for neurological disorder data. An extensive discussion on the possibility of enhancing the abilities of AI systems using the different data analysis is included. The book recollects several applicable basic preliminaries of the different AI networks and models, while also highlighting basic processes in image processing for various neurological disorders. It also reports on several applications to image processing and explores numerous topics concerning the role of big data analysis in addressing signal and image processing in various real-world scenarios involving neurological disorders. This cutting-edge book highlights the analysis of medical data, together with novel procedures and challenges for handling neurological signals and images. It will help engineers, researchers and software developers to understand the concepts and different models of AI and data analysis. To help readers gain a comprehensive grasp of the subject, it focuses on three key features: ● Presents outstanding concepts and models for using AI in clinical applications involving neurological disorders, with clear descriptions of image representation, feature extraction and selection. ● Highlights a range of techniques for evaluating the performance of proposed CAD systems for the diagnosis of neurological disorders. ● Examines various signal and image processing methods for efficient decision support systems. Soft computing, machine learning and optimization algorithms are also included to improve the CAD systems used.
Download or read book Fundamental Statistical Methods for Analysis of Alzheimer s and Other Neurodegenerative Diseases written by Katherine E. Irimata and published by Johns Hopkins University Press. This book was released on 2020-05-05 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Allowing more people to aid in analyzing data—while promoting constructive dialogues with statisticians—this book will hopefully play an important part in unlocking the secrets of these confounding diseases.
Download or read book Fundamental Statistical Methods for Analysis of Alzheimer s and Other Neurodegenerative Diseases written by Katherine E. Irimata and published by JHU Press. This book was released on 2020-05-05 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: A statistics textbook that delivers essential data analysis techniques for Alzheimer's and other neurodegenerative diseases. Alzheimer's disease is a devastating condition that presents overwhelming challenges to patients and caregivers. In the face of this relentless and as-yet incurable disease, mastery of statistical analysis is paramount for anyone who must assess complex data that could improve treatment options. This unique book presents up-to-date statistical techniques commonly used in the analysis of data on Alzheimer's and other neurodegenerative diseases. With examples drawn from the real world that will make it accessible to disease researchers, practitioners, academics, and students alike, this volume • presents code for analyzing dementia data in statistical programs, including SAS, R, SPSS, and Stata • introduces statistical models for a range of data types, including continuous, categorical, and binary responses, as well as correlated data • draws on datasets from the National Alzheimer's Coordinating Center, a large relational database of standardized clinical and neuropathological research data • discusses advanced statistical methods, including hierarchical models, survival analysis, and multiple-membership • examines big data analytics and machine learning methods Easy to understand but sophisticated in its approach, Fundamental Statistical Methods for Analysis of Alzheimer's and Other Neurodegenerative Diseases will be a cornerstone for anyone looking for simplicity in understanding basic and advanced statistical data analysis topics. Allowing more people to aid in analyzing data—while promoting constructive dialogues with statisticians—this book will hopefully play an important part in unlocking the secrets of these confounding diseases.
Download or read book Handbook of Research on Disease Prediction Through Data Analytics and Machine Learning written by Rani, Geeta and published by IGI Global. This book was released on 2020-10-16 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: By applying data analytics techniques and machine learning algorithms to predict disease, medical practitioners can more accurately diagnose and treat patients. However, researchers face problems in identifying suitable algorithms for pre-processing, transformations, and the integration of clinical data in a single module, as well as seeking different ways to build and evaluate models. The Handbook of Research on Disease Prediction Through Data Analytics and Machine Learning is a pivotal reference source that explores the application of algorithms to making disease predictions through the identification of symptoms and information retrieval from images such as MRIs, ECGs, EEGs, etc. Highlighting a wide range of topics including clinical decision support systems, biomedical image analysis, and prediction models, this book is ideally designed for clinicians, physicians, programmers, computer engineers, IT specialists, data analysts, hospital administrators, researchers, academicians, and graduate and post-graduate students.
Download or read book Imaging in Neurodegenerative Disorders written by Luca Saba and published by Oxford University Press, USA. This book was released on 2015 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text summarizes the latest developments in imaging techniques and other new diagnostic methods as applied to the neurodegenerative disorders.
Download or read book Big Data in Psychiatry and Neurology written by Ahmed Moustafa and published by Academic Press. This book was released on 2021-06-11 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Big Data in Psychiatry and Neurology provides an up-to-date overview of achievements in the field of big data in Psychiatry and Medicine, including applications of big data methods to aging disorders (e.g., Alzheimer’s disease and Parkinson’s disease), mood disorders (e.g., major depressive disorder), and drug addiction. This book will help researchers, students and clinicians implement new methods for collecting big datasets from various patient populations. Further, it will demonstrate how to use several algorithms and machine learning methods to analyze big datasets, thus providing individualized treatment for psychiatric and neurological patients. As big data analytics is gaining traction in psychiatric research, it is an essential component in providing predictive models for both clinical practice and public health systems. As compared with traditional statistical methods that provide primarily average group-level results, big data analytics allows predictions and stratification of clinical outcomes at an individual subject level. Discusses longitudinal big data and risk factors surrounding the development of psychiatric disorders Analyzes methods in using big data to treat psychiatric and neurological disorders Describes the role machine learning can play in the analysis of big data Demonstrates the various methods of gathering big data in medicine Reviews how to apply big data to genetics
Download or read book Neurodegenerative Diseases Biomarkers written by Philip V. Peplow and published by . This book was released on 2021 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents recent data on the latest achievements in new and emerging technologies for biomarkers and for innovations in their assessment. The chapters cover topics such as activation of microglia and macrophages in neurodegenerative diseases; oxidative stress and cellular dysfunction in neurodegenerative diseases; TSPO PET imaging as a biomarker of neuroinflammation in neurodegenerative disorders; and imaging biomarkers in Huntington's disease and amyotrophic lateral sclerosis. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Neurodegenerative Diseases Biomarkers: Towards Translating Research to Clinical Practice is a valuable resource for both experimental and clinical experts in the field of neurodegenerative diseases who are looking to expand their knowledge of novel biomarkers in different types of neurodegenerative diseases.
Download or read book AI and Neuro Degenerative Diseases written by Loveleen Gaur and published by Springer Nature. This book was released on with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Decision Support Systems for Neurological Disorders written by Hemanth D. Jude and published by Academic Press. This book was released on 2021-03-30 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Decision Support Systems for Neurological Disorders provides readers with complete coverage of advanced computer-aided diagnosis systems for neurological disorders. While computer-aided decision support systems for different medical imaging modalities are available, this is the first book to solely concentrate on decision support systems for neurological disorders. Due to the increase in the prevalence of diseases such as Alzheimer, Parkinson’s and Dementia, this book will have significant importance in the medical field. Topics discussed include recent computational approaches, different types of neurological disorders, deep convolution neural networks, generative adversarial networks, auto encoders, recurrent neural networks, and modified/hybrid artificial neural networks. Includes applications of computer intelligence and decision support systems for the diagnosis and analysis of a variety of neurological disorders Presents in-depth, technical coverage of computer-aided systems for tumor image classification, Alzheimer’s disease detection, dementia detection using deep belief neural networks, and morphological approaches for stroke detection Covers disease diagnosis for cerebral palsy using auto-encoder approaches, contrast enhancement for performance enhanced diagnosis systems, autism detection using fuzzy logic systems, and autism detection using generative adversarial networks Written by engineers to help engineers, computer scientists, researchers and clinicians understand the technology and applications of decision support systems for neurological disorders
Download or read book Neurodegeneration written by Dennis Dickson and published by John Wiley & Sons. This book was released on 2011-09-09 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most textbooks on neurodegenerative disorders have used a classification scheme based upon either clinical syndromes or anatomical distribution of the pathology. In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries. Major advances in molecular genetics and the application of biochemical and immunocytochemical techniques to neurodegenerative disorders have generated this new approach. Throughout most of the current volume, diseases are clustered according to the proteins that accumulate within cells (e.g. tau, α-synuclein and TDP-43) and in the extracellular compartments (e.g. β-amyloid and prion proteins) or according to a shared pathogenetic mechanism, such as trinucleotide repeats, that are a feature of specific genetic disorders. Chapters throughout the book conform to a standard lay-out for ease of access by the reader and are written by a panel of International Experts Since the first edition of this book, major advances have been made in the discovery of common molecular mechanisms between many neurodegenerative diseases most notably in the frontotemporal lobar degenerations (FTLD) and motor neuron disease or amyotrophic lateral sclerosis. This book will be essential reading for clinicians, neuropathologists and basic neuroscientists who require the firm up-to-date knowledge of mechanisms, diagnostic pathology and genetics of Neurodegenerative diseases that is required for progress in therapy and management.
Download or read book Early Detection of Neurological Disorders Using Machine Learning Systems written by Paul, Sudip and published by IGI Global. This book was released on 2019-06-28 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: While doctors and physicians are more than capable of detecting diseases of the brain, the most agile human mind cannot compete with the processing power of modern technology. Utilizing algorithmic systems in healthcare in this way may provide a way to treat neurological diseases before they happen. Early Detection of Neurological Disorders Using Machine Learning Systems provides innovative insights into implementing smart systems to detect neurological diseases at a faster rate than by normal means. The topics included in this book are artificial intelligence, data analysis, and biomedical informatics. It is designed for clinicians, doctors, neurologists, physiotherapists, neurorehabilitation specialists, scholars, academics, and students interested in topics centered on biomedical engineering, bio-electronics, medical electronics, physiology, neurosciences, life sciences, and physics.
Download or read book Etiology of Parkinson s Disease written by Jonas H. Ellenberg and published by CRC Press. This book was released on 1995-03-01 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.
Download or read book Molecular Mechanisms of Neurodegenerative Diseases written by Marie-Francoise Chesselet and published by Springer Science & Business Media. This book was released on 2000-10-19 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the unprecedented identification of new mutation mechanisms in neurodegenerative diseases and the emergence of common mechanisms among diseases that were once considered unrelated, neurobiologists are poised for the development of new therapies based on high throughput screenings and a better understanding of the molecular and cellular mechanisms leading to neurodegeneration. In Molecular Mechanisms of Neurodegenerative Diseases, Marie-Francoise Chesselet, MD, PhD, and a panel of leading researchers and neurologists from industry and academia critically review the most recent advances from different yet complementary points of view. Focusing on Alzheimer's, Parkinson's, and CAG triplet repeat diseases, the authors show how studies of cellular and genetically engineered animal models have enhanced our understanding of the molecular mechanisms of neurodegenerative diseases and may lead to the development of new therapeutics. Topics include the role of Ab toxicity, glial cells, and inflammation in Alzheimer's disease; the formation of abnormal protein fragments across several diseases, the impact of dopamine and mitochondrial dysfunction on neurodegeneration; and the potential of genetics to identify the molecular mechanisms of neurodegenerative diseases. Authoritative and insightful, Molecular Mechanisms of Neurodegenerative Diseases synthesizes the novel ideas and concepts now emerging to create a fresh understanding of neurodegenerative disorders, one that promises to lead to powerful new therapies that prevent, delay the onset, slow the progression, or even cure these cruel diseases.
Download or read book Multi omics Epigenomics and Computational Analysis of Neurodegenerative Disorders written by Manoj Kumar Jaiswal and published by Frontiers Media SA. This book was released on 2022-08-03 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nanobiotechnology in Neurodegenerative Diseases written by Mahendra Rai and published by Springer Nature. This book was released on 2019-12-02 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on neurodegenerative diseases which have become a major threat to human health. Neurodegenerative diseases are age related disorders and have become increasingly prevalent in the elderly population in recent years. Hence, there is an urgent need to study and develop new strategies and alternative methods for the treatment of neurodegenerative diseases. This book showcases the promises that nanobiotechnology brings in research, diagnosis, and treatment of neurodegenerative diseases. It is very beneficial for varied group of readers including nanotechnologists, biotechnologists, pharmacists, medical professionals, bioengineers, biochemists and researchers working in this field. Nanobiotechnology in Neurodegenerative Diseases include various chapters including neurodegeneration and neurodegenerative diseases, nanotechnology for the rescue of neurodegenerative diseases, promising potential of nanomaterials for diagnosis and therapy of neurodegenerative diseases, nanotechnology mediated nose-to-brain drug delivery, and formulation and characterization of intranasal nanoparticles of antiretroviral drugs.
Download or read book Oxidative Stress and Neurodegenerative Disorders written by G. Ali Qureshi and published by Elsevier. This book was released on 2007-03-22 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mechanisms against oxygen radicals may be weakened and/or overwhelmed. DNA is a potential target for oxidative damage, and genomic damage can contribute to neuropathogenesis. It is important therefore to identify tools for the quantitative analysis of DNA damage in models on neurological disorders. This book presents detailed information on various neurodegenerative disorders and their connection with oxidative stress. This information will provide clinicians with directions to treat these disorders with appropriate therapy and is also of vital importance for the drug industries for the design of new drugs for treatment of degenerative disorders. * Contains the latest information on the subject of neurodegenerative disorders * Reflects on various factors involved in degeneration and gives suggestions for how to tackle these problems
Download or read book The Benefits of Natural Products for Neurodegenerative Diseases written by M. Mohamed Essa and published by Springer. This book was released on 2016-09-20 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focuses on the effects of natural products and their active components on brain function and neurodegenerative disease prevention. Phytochemicals such as alkaloids, terpenes, flavanoids, isoflavones, saponins etc are known to possess protective activity against many neurological diseases. The molecular mechanisms behind the curative effects rely mainly on the action of phytonutrients on distinct signaling pathways associated with protein folding and neuro-inflammation. The diverse array of bioactive nutrients present in these natural products plays a pivotal role in prevention and cure of various neurodegenerative diseases, disorders, or insults, such as Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, traumatic brain injury, and other neuronal dysfunctions. However, the use of these antioxidants in the management of neurodegenerative conditions has so far been not well understood. This is a comprehensive collection addressing the effects on the brain of natural products and edible items such as reservatrol, curcumin, gingerol, fruits, vegetables, nuts, and marine products.
