Download or read book D marche d optimisation des proc d s de nettoyage manuel des quipements de production en vue de la validation written by Lala Khyra Mokhtari and published by . This book was released on 2011 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Le nettoyage des équipements de production permet de lutter contre la contamination. Afin de garantir la reproductibilité et l’efficacité du procédé de nettoyage appliqué à l’équipement, celui-ci fait l’objet d’une validation. Parmi les différentes méthodes de nettoyage, le nettoyage manuel est une méthode de nettoyage complexe à valider étant donné le degré de variabilité d’un technicien à l’autre mais également d’un nettoyage à l’autre. L’objectif de ce travail a consisté à proposer une démarche d’optimisation des procédés de nettoyage manuel dans un site de fabrication de formes sèches. La première partie de cette thèse se consacre à la contamination dans l’industrie pharmaceutique. En effet, y sont présentées les différents contaminants rencontrés ainsi que les moyens permettant de maitriser cette contamination. La seconde partie traite du nettoyage des équipements de production ; elle décrit les paramètres influençant le nettoyage, les agents de nettoyage utilisés ainsi que les différentes méthodes de nettoyage employées en industrie. La troisième partie développe la validation du nettoyage d’un point de vue réglementaire et pratique. Enfin, la dernière partie expose un exemple de démarche pour optimiser des procédures de nettoyage manuel d’équipements de production dans un site de fabrication de formes sèches.

Download or read book Validation de nettoyage des quipements d un atelier de fabrication et de conditionnement de comprim s written by Magali Alvarez and published by . This book was released on 2014 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Le nettoyage des équipements de production est une étape de fabrication à considérer comme critique, car elle peut avoir un impact direct sur la qualité, l'efficacité et la sécurité des médicaments. Valider cette étape critique est aujourd'hui incontournable et nécessaire pour garantir la maîtrise des opérations de nettoyage lors de la fabrication des médicaments. Malgré sa consommation en ressources importante (humaines et matérielles), mais aussi en terme de temps, elle peut être considérée comme un tremplin afin de faire évoluer les pratiques pour améliorer la performance industrielle et optimiser les coûts et les délais alloués à ces opérations de nettoyage, mais elle peut également représenter un gain en terme d'hygiène et de sécurité industrielle. Le projet de validation de nettoyage initié à l'usine de WPS à Dakar Sénégal s'inscrit dans une volonté d'amélioration significative de la conformité aux règles des BPF. Lors de cet exercice de validation, certaines erreurs, limites et difficultés n'ont pu permettre d'aboutir à un projet concluant. La validation de nettoyage est un processus qualité qui se doit de s'inscrire dans une démarche d'amélioration continue.

Download or read book Validation de nettoyage des quipements de production written by Anne Burtin and published by . This book was released on 2014 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Les exigences en termes de nettoyage des équipements de production sont de plus en plus strictes, suite à un défaut de nettoyage, des lots de médicaments peuvent être rappelés, ce qui peut affecter l'image de marque d'une entreprise. Suivant le type d'équipement, le nettoyage peut ne pas être effectué de la même façon mais l'objectif principal est d'obtenir un équipement propre d'un point de vue microbiologique et physico-chimique. Pour vérifier l'efficacité du nettoyage une validation doit être mise en place. Cette validation a pour but de garantir l'efficacité du nettoyage. Toute une démarche de validation existe mais les normes d'acceptation sont propres à chaque laboratoire puisqu'elles dépendent des équipements et du type de produits. Ce rapport illustre la validation de la partie microbiologique du nettoyage des équipements de fabrication de lyophilisats oraux.

Download or read book Validation de proc d s de nettoyage d quipements de production appliqu e aux formes non obligatoirement st riles written by Denisa Ebermann and published by . This book was released on 1999 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Optimisation et validation du nettoyage des pi ces machines des ateliers de production written by Nathalie Gaudin and published by . This book was released on 1999 with total page 29 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book VALIDATION DU NETTOYAGE DES EQUIPEMENTS EN PRODUCTION written by CHRISTOPHE.. BRUHL and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nettoyage du mat riel de production written by N'drin Fernande Yace and published by . This book was released on 1999 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Validation de nettoyage en production industrielle written by Laure Voisin and published by . This book was released on 2008 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: La validation de nettoyage des équipements de production dans l’industrie pharmaceutique contribue à la garantie de la qualité des médicaments fabriqués, c’est pourquoi une stratégie de management doit être adoptée. Actuellement, de nombreux travaux permettent d’orienter la réflexion mais chaque site industriel doit adapter une stratégie de management à ses propres besoins et objectifs. L’aspect économique, la politique qualité de l’entreprise et les différents paramètres techniques associés sont autant de points à aborder en validation de nettoyage. Un exemple de validation de nettoyage par dosage du carbone organique total illustre la mise en place de cette stratégie de management.

Download or read book Mise en conformit et validation des proc dures de nettoyage des ateliers et des quipements de production Sucres cuits et gommes written by Christine CHAUBELL MOTOS and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Validation chimique de nettoyage written by Benjamin Vallet and published by . This book was released on 2002 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Organisation et validation du nettoyage d quipements de fabrication du Service production vaccins bact riens de PMsv written by Sophie Legrand Luxembourger and published by . This book was released on 1994 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Faecal Sludge Management written by Linda Strande and published by IWA Publishing. This book was released on 2014-08-15 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is estimated that literally billions of residents in urban and peri-urban areas of Africa, Asia, and Latin America are served by onsite sanitation systems (e.g. various types of latrines and septic tanks). Until recently, the management of faecal sludge from these onsite systems has been grossly neglected, partially as a result of them being considered temporary solutions until sewer-based systems could be implemented. However, the perception of onsite or decentralized sanitation technologies for urban areas is gradually changing, and is increasingly being considered as long-term, sustainable options in urban areas, especially in low- and middle-income countries that lack sewer infrastructures. This is the first book dedicated to faecal sludge management. It compiles the current state of knowledge of the rapidly evolving field of faecal sludge management, and presents an integrated approach that includes technology, management, and planning based on Sandecs 20 years of experience in the field. Faecal Sludge Management: Systems Approach for Implementation and Operation addresses the organization of the entire faecal sludge management service chain, from the collection and transport of sludge, and the current state of knowledge of treatment options, to the final end use or disposal of treated sludge. The book also presents important factors to consider when evaluating and upscaling new treatment technology options. The book is designed for undergraduate and graduate students, and engineers and practitioners in the field who have some basic knowledge of environmental and/or wastewater engineering.

Download or read book Global Burden of Disease and Risk Factors written by Alan D. Lopez and published by World Bank Publications. This book was released on 2006-04-02 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: Strategic health planning, the cornerstone of initiatives designed to achieve health improvement goals around the world, requires an understanding of the comparative burden of diseases and injuries, their corresponding risk factors and the likely effects of invervention options. The Global Burden of Disease framework, originally published in 1990, has been widely adopted as the preferred method for health accounting and has become the standard to guide the setting of health research priorities. This publication sets out an updated assessment of the situation, with an analysis of trends observed since 1990 and a chapter on the sensitivity of GBD estimates to various sources of uncertainty in methods and data.

Download or read book How to Design Wastewater Systems for Local Conditions in Developing Countries written by David M. Robbins and published by IWA Publishing. This book was released on 2014-03-15 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a practical handbook providing a step-by-step approach to the techniques used for characterizing wastewater sources and investigating sites where collection, treatment and reuse/disposal technologies will be installed. It is intended to help enable local implementation of on-site and decentralized wastewater management system (DWMS)for wide scale use in development settings. How to Design Wastewater Systems for Local Conditions in Developing Countries helps local service providers and regulatory officials make informed decisions through the use of tools, checklists and case studies. It includes a link to a web based community of on-site and decentralized wastewater professionals, which contains related tools and case studies. This handbook serves as a reference for training classes, certification programs, and higher education programs in civil and sanitary engineering. There is an increasing interest on the part of local government officials and private sector service providers to implement wastewater treatment systems to solve sanitation problems. The model presented in this handbook promotes activities that first generate data related to source and site conditions that represent critical inputs, and then applies this information to the technology selection process. Matching the most appropriate technologies to the specific needs of the wastewater project is the key that leads to long term sustainability. How to Design Wastewater Systems for Local Conditions in Developing Countries is an invaluable resource for public sector decision makers and private sector service providers in developing countries. It is also a useful text for students at engineering colleges in developing countries interested in taking a class that teaches the methods of decentralized wastewater management system (DWMS) development.

Download or read book Compendium of Sanitation Systems and Technologies written by Elizabeth Tilley and published by . This book was released on 2014 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Metamorphoses written by Emanuele Coccia and published by John Wiley & Sons. This book was released on 2021-06-09 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are all fascinated by the mystery of metamorphosis – of the caterpillar that transforms itself into a butterfly. Their bodies have almost nothing in common. They don’t share the same world: one crawls on the ground and the other flutters its wings in the air. And yet they are one and the same life. Emanuele Coccia argues that metamorphosis – the phenomenon that allows the same life to subsist in disparate bodies – is the relationship that binds all species together and unites the living with the non-living. Bacteria, viruses, fungi, plants, animals: they are all one and the same life. Each species, including the human species, is the metamorphosis of all those that preceded it – the same life, cobbling together a new body and a new form in order to exist differently. And there is no opposition between the living and the non-living: life is always the reincarnation of the non-living, a carnival of the telluric substance of a planet – the Earth – that continually draws new faces and new ways of being out of even the smallest particle of its disparate body. By highlighting what joins humans together with other forms of life, Coccia’s brilliant reflection on metamorphosis encourages us to abandon our view of the human species as static and independent and to recognize instead that we are part of a much larger and interconnected form of life.

Download or read book Tribal Wisdom for Business Ethics written by Grace Ann Rosile and published by Emerald Group Publishing Limited. This book was released on 2016-11-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, leading native and non-native scholars present a fascinating view of American Indian tribal values and indigenous cultures. This 'Tribal Wisdom' offers an ethic of business practice that is relationship-based and community-oriented, fostering a harmonious web of life which includes the natural environment.