Download or read book Inflammation in Heart Failure written by Matthijs Blankesteijn and published by Academic Press. This book was released on 2014-12-05 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation in Heart Failure, edited by W. Matthijs Blankesteijn and Raffaele Altara, is the first book in a decade to provide an in-depth assessment on the causes, symptoms, progression and treatments of cardiac inflammation and related conditions. This reference uses two decades of research to introduce new methods for identifying inflammatory benchmarks from early onset to chronic heart failure and specifically emphasizes the importance of classifying at-risk subgroups within large populations while determining the patterns of cytokines in such classifications. Further, the book details clinical applications of the pathophysiological mechanisms of heart failure, diagnosis and therapeutic strategies. Inflammation in Heart Failure’s breadth of subject matter, easy-to-follow structure, portability, and high-quality illustrations create an accessible benefit for researchers, clinicians and students. Presents updated information and research on the relevant inflammatory mediators of heart failure to aid in targeting future translational research as well as the improvement of early diagnosis and treatment Provides research into better understanding the different inflammatory mediators that signal the underlying diseases that potentially lead to heart failure Contains 20 years of research, offering a brief overview of the topic leading to current opinions on, and treatment of, heart failure Provides a structured, systematic and balanced overview of the role of inflammation in heart failure making it a useful resource for researchers and clinicians, as well as those studying cardiovascular diseases
Download or read book Cytokines and the Heart written by Ursula Müller-Werdan and published by Landes Bioscience. This book was released on 1996 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Oxidative Stress in Heart Diseases written by Sajal Chakraborti and published by Springer Nature. This book was released on 2019-11-06 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.
Download or read book The Role of Inflammatory Mediators in the Failing Heart written by Douglas L. Mann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although clinicians have recognized the importance of inflammatory mediators in the pathogenesis of heart disease for well over 200 years, it has taken nearly as many years for clinicians and scientists to focus on the basic biological mechanisms by which inflammatory mediators contribute to the pathogenesis of cardiac disease states. Over the past decade there has been increasing interest in the potential role that inflammatory mediators, play in a variety of cardiac disease states, including chronic heart failure. The Role of Inflammatory Mediators in the Failing Heart provides a state-of-the-art review on inflammatory mediators and the failing heart. This book will serve both as a useful introduction to the field, as well as an update for those interested in the role of inflammatory mediators and the failing heart.
Download or read book Metabolic Cardiomyopathy written by H. Böhles and published by CRC Press. This book was released on 2004 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.
Download or read book Cytokines Novel Cell Death Models and Pathways in Cardiovascular Diseases written by Yuli Huang and published by Frontiers Media SA. This book was released on 2023-09-26 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cytokines are soluble proteins secreted by a wide variety of cells in the body, playing crucial roles in many physiological responses and are involved in the pathophysiology of cardiovascular diseases (CVDs). Recently, there is great progress in discoveries that some novel cytokines, including secreted frizzled-related proteins (SFRPs), adiponectin, and C1q/TNF-Related Proteins (CTRPs), can perform a protective effect in cardiometabolic diseases, heart failure and coronary heart disease. However, the mechanisms underlying the molecular and pathophysiological actions of these cytokines in CVDs are still vague. Novel mechanisms of cell death including pyroptosis, autophagy, ferroptosis, cuproptosis, and PANoptosis have been considered novel therapeutic targets for CVDs. Some cytokines have been shown to regulate the cell death pathway in the incidence and development of CVDs. Further investigations are needed to understand the link between these novel cytokines and novel cell death models and pathways in CVDs.
Download or read book Cardioimmunology Inflammation and Immunity in Cardiovascular Disease written by Mohamed Boutjdir and published by Frontiers Media SA. This book was released on 2020-01-30 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Role of Cytokines in the Regulation of Cardiac BNP written by Yael Fanny Meirovich and published by . This book was released on 2007 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension written by Toshio Nakanishi and published by Springer Nature. This book was released on 2020-02-28 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.
Download or read book Lipids in Health and Disease written by Peter Quinn and published by Springer Science & Business Media. This book was released on 2008-08-27 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsaturated fatty acids and their derivatives. New insights into the role of fatty acid synthesis and eicosenoid function in tumour progression and metastasis are presented.
Download or read book The Failing Heart written by Naranjan S. Dhalla and published by Lippincott Williams & Wilkins. This book was released on 1995 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Diabetic Heart written by Makoto Nagano and published by New York : Raven Press. This book was released on 1991 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cytokines and the Heart written by Ursula Müller-Werdan and published by Springer. This book was released on 1996-02 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the molecular mechanisms underlying septic cardiomyopathy, a main feature of septic shock and multiple organ dysfunction syndrome, which are the leading causes of death in intensive care patients. Cytokines play a very prominent pathogenetic role in this myocardial depression, with septic cardiomyopathy being the cardiac disease entity, where knowledge about cytokine action on the heart has most accumulated.
Download or read book SIDS Sudden Infant and Early Childhood Death written by Roger W. Byard and published by . This book was released on 2018-04 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers aspects of sudden infant and early childhood death, ranging from issues with parental grief, to the most recent theories of brainstem neurotransmitters. It also deals with the changes that have occurred over time with the definitions of SIDS (sudden infant death syndrome), SUDI (sudden unexpected death in infancy) and SUDIC (sudden unexpected death in childhood). The text will be indispensable for SIDS researchers, SIDS organisations, paediatric pathologists, forensic pathologists, paediatricians and families, in addition to residents in training programs that involve paediatrics. It will also be of use to other physicians, lawyers and law enforcement officials who deal with these cases, and should be a useful addition to all medical examiner/forensic, paediatric and pathology departments, hospital and university libraries on a global scale. Given the marked changes that have occurred in the epidemiology and understanding of SIDS and sudden death in the very young over the past decade, a text such as this is very timely and is also urgently needed.
Download or read book Cardioprotection written by Derek Hausenloy and published by Oxford University Press. This book was released on 2009-08-20 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronary heart disease (CHD) is the leading cause of death worldwide. Cardioprotection refers to the prevention of CHD and the clinical improvement in patients suffering from cardiovascular problems.
Download or read book Smart at Heart written by Dr. Malissa Wood and published by Celestial Arts. This book was released on 2011-12-27 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: A breakthrough mind-body program to build a strong, healthy, and happy heart, for women at risk for or diagnosed with heart disease, from the Harvard-trained cardiologist behind the Women’s Heart Health Program at Massachusetts General Hospital. Heart disease is the number-one killer of American women, and prevention and healing require integrative approaches to address the whole heart—physical, emotional, and spiritual. Smart at Heart’s holistic program includes strategies to improve heart health by addressing ten bridges that link the physical and emotional hearts, including the mental health, relationship, and communication bridges. This book guides readers through evaluating their current state of physical and emotional health and then empowers them with solutions to strengthen each bridge to create a healthy, whole heart.
Download or read book Cytokines and Pain written by L.R. Watkins and published by Springer. This book was released on 2013-03-08 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the past few years, it has become recognized that the immune system communicates to the brain. Substances released from activated immune cells (cytokines) stimulate peripheral nerves, thereby signaling the brain and spinal cord that infection/inflammation has occurred. Additionally, peripheral infection/inflammation leads to de novo synthesis and release of cytokines within the brain and spinal cord. Thus, cytokines effect neural activation both peripherally and centrally. Through this communication pathway, cytokines such as interleukin-1, interleukin-6 and tumor necrosis factor markedly alter brain function, physiology and behavior. One important but underrecognized aspect of this communication is the dramatic impact that immune activation has on pain modulation. The purpose of this book is to examine, for the first time, immune-to-brain communication from the viewpoint of its effect on pain processing. It is aimed both at the basic scientist and health care providers, in order to clarify the major role that substances released by immune cells play in pain modulation. This book contains chapters contributed by all of the major laboratories focused on understanding how cytokines modulate pain. These chapters provide a unique vantage point from which to examine this question, as the summarized work ranges from evolutionary approaches across diverse species, to the basics of the immune response, to the effect of cytokines on peripheral and central nervous system sites, to therapeutic potential in humans.
