Download or read book Current Protocols Essential Laboratory Techniques written by Sean R. Gallagher and published by John Wiley & Sons. This book was released on 2012-03-19 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest title from the acclaimed Current Protocols series, Current Protocols Essential Laboratory Techniques, 2e provides the new researcher with the skills and understanding of the fundamental laboratory procedures necessary to run successful experiments, solve problems, and become a productive member of the modern life science laboratory. From covering the basic skills such as measurement, preparation of reagents and use of basic instrumentation to the more advanced techniques such as blotting, chromatography and real-time PCR, this book will serve as a practical reference manual for any life science researcher. Written by a combination of distinguished investigators and outstanding faculty, Current Protocols Essential Laboratory Techniques, 2e is the cornerstone on which the beginning scientist can develop the skills for a successful research career.
Download or read book Current Protocols in Molecular Biology written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Using the Engineering Literature written by Bonnie A. Osif and published by CRC Press. This book was released on 2006-08-23 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of engineering is becoming increasingly interdisciplinary, and there is an ever-growing need for engineers to investigate engineering and scientific resources outside their own area of expertise. However, studies have shown that quality information-finding skills often tend to be lacking in the engineering profession. Using the Engineerin
Download or read book Handbook of Methods and Instrumentation in Separation Science written by and published by Academic Press. This book was released on 2009-11-11 with total page 881 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Methods and Instrumentation in Separation Science, Volume 1 provides concise overviews and summaries of the main methods used for separation. It is based on the Encyclopedia of Separation Science. The handbook focuses on the principles of methods and instrumentation. It provides general concepts concerning the subject matter; it does not present specific procedures. This volume discusses the separation processes including affinity methods, analytical ultracentrifugation, centrifugation, chromatography, and use of decanter centrifuge and dye. Each methodology is defined and compared with other separation processes. It also provides specific techniques, principles, and theories concerning each process. Furthermore, the handbook presents the applications, benefits, and validation of the processes described in this book. This handbook is an excellent reference for biomedical researchers, environmental and production chemists, flavor and fragrance technologists, food and beverage technologists, academic and industrial librarians, and nuclear researchers. Students and novices will also find this handbook useful for practice and learning. - One-stop source for information on separation methods - General overviews for quick orientation - Ease of use for finding results fast - Expert coverage of major separation methods - Coverage of techniques for all sizes of samples, pico-level to kilo-level
Download or read book Protein Ligand Interactions written by Holger Gohlke and published by John Wiley & Sons. This book was released on 2012-04-06 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic understanding of the factors governing protein-ligand interactions, followed by a comparison of key experimental methods (calorimetry, surface plasmon resonance, NMR) used in generating interaction data. The second half of the book is devoted to insilico methods of modeling and predicting molecular recognition and binding, ranging from first principles-based to approximate ones. Here, as elsewhere in the book, emphasis is placed on novel approaches and recent improvements to established methods. The final part looks at unresolved challenges, and the strategies to address them. With the content relevant for all drug classes and therapeutic fields, this is an inspiring and often-consulted guide to the complexity of protein-ligand interaction modeling and analysis for both novices and experts.
Download or read book Biochemical Methods written by Alfred Pingoud and published by Wiley-VCH. This book was released on 2002-10-11 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a profound overview on the relevant biochemical techniques. Moreover, it refers to laboratory equipment and safety aspects and explains how to obtain relevant biochemical information. It provides an introduction into physical-chemical processes and mathematical methods required for the interpretation of data. Principles of expensive instrumental analysis are also explained and a presentation of safety considerations and regulatory issues according to international requirements is given. With its practical approach the book is not only highly useful for professionals - laboratory technicians and scientists - but also for students. Special feature: a CD-ROM on quantitative analysis of biochemical experiments! "... An ideal how-to for those working in biochemistry." CHEMIE in unserer Zeit "... and anyone working in a biochemical laboratory will find it useful. Strongly recommended." Laboratory News
Download or read book Methods in Protein Design written by and published by Academic Press. This book was released on 2013-02-14 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers methods in protein design and it has chapters on such topics as protein switch engineering by domain insertion, evolution based design of proteins, and computationally designed proteins. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers methods in protein design - Contains chapters with such topics as protein switch engineering by domain insertion, evolution-based design of proteins, and computationally designed proteins
Download or read book Research in Computational Molecular Biology written by Minghua Deng and published by Springer. This book was released on 2013-03-12 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 17th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2013, held in Beijing, China, in April 2013. The 32 revised full papers were carefully reviewed and selected from 167 submissions. The papers cover a wide range of topics including molecular sequence analysis; genes and regulatory elements; molecular evolution; gene expression; biological networks; sequencing and genotyping technologies; genomics; epigenomics; metagenomics; population, statistical genetics; systems biology; computational proteomics; computational structural biology; imaging; large-scale data management.
Download or read book Short Protocols in Protein Science written by John E. Coligan and published by Wiley-Blackwell. This book was released on 2003-10-24 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: Short Protocols in Protein Science provides condensed descriptions of more than 500 protocols compiled from Current Protocols in Protein Science. Drawing from both the original "core" manual as well as the quarterly update service, this compendium includes all step-by-step descriptions of the principal methods covered in Current Protocols in Protein Science.
Download or read book Current Protocols in Protein Science written by and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Isotope Labeling of Biomolecules Labeling Methods written by and published by Academic Press. This book was released on 2015-11-26 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: Isotope Labeling of Biomolecules – Labeling Methods, the latest volume of the Methods in Enzymology series contains comprehensive information on stable isotope labeling methods and applications for biomolecules. - Contains contributions from leading authorities in the field of isotope labeling of biomolecules - Informs and updates on the latest developments in the field - Provides comprehensive information on stable isotope labeling methods and applications for biomolecules
Download or read book Therapeutic Proteins and Peptides written by and published by Academic Press. This book was released on 2018-04-18 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Therapeutic Proteins and Peptides, Volume 112 in an ongoing series promotes further research in the discovery of new therapeutic targets that can be affected by therapeutic proteins and peptides to cure or manage symptoms of human diseases, with this release focusing on the Rational Design of Stable Liquid Formulations of Biopharmaceuticals, Formulation strategies for peptides, proteins and antibodies using nanotechnology, the Solution structural dynamics of therapeutic peptides and their adsorption on plasmonic nanoparticles, Enzymatic approaches of protein-polymer conjugation, Chimeric small antibody fragments as a strategy to deliver therapeutic payloads, Smart cell-penetrating peptide-based techniques for cytoplasmic delivery of therapeutic macromolecules, and more. - Describes advances in the discovery and application of therapeutic proteins/peptides which allow better targeting to the site of treatment and cause fewer adverse effects when compared to chemical compounds used for disease treatment - Targeted to a very wide audience of specialists, researchers and students - Written by well-renown authorities in their field - Includes a number of high quality illustrations, figures and tables
Download or read book Metallointercalators written by Janice Aldrich-Wright and published by Springer. This book was released on 2011-04-06 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive treatment of the characterisation techniques used in investigating inorganic and organic molecules that interact with biomolecules is presented to the reader in a clear fashion. The work consists of two parts: (i) synthetic aspects of metallointercalators along with targeting and improving transport and (ii) the various techniques that are used for probing their interactions, such as; DNA-NMR, PGSE-NMR, DNA ESI-MS, Linear and Circular Dichroism, Fluorescence Spectroscopy, Confocal Microscopy, Viscosity, TGA and dialysis, Microarrays, biological analysis. Chapters are devoted to the synthesis and the techniques used to study the interactions of inorganic complexes with biomolecules. Considerably detailed examples are used to help illustrate the application of these techniques. This book is a useful resource for an array of inorganic and organic advanced undergraduate and graduate courses and for researchers in drug discovery.
Download or read book Literature Search Strategies for Interdisciplinary Research written by Linda G. Ackerson and published by Rowman & Littlefield. This book was released on 2007 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: The amount of published literature can be overwhelming for scientists and researchers moving from a broad disciplinary research area to a more specialized one, particularly in fields that use information from more than one discipline. Without a focused inquiry, the researcher may find too little information or may be overcome by too much. Striking the correct balance of information is the focus of Literature Search Strategies for Interdisciplinary Research. This useful reference tool studies diverse interdisciplinary areas revealing the general and individual qualities that dictate the strategies of successful searches. Beginning with a bare-bones search strategy for finding primary research in interdisciplinary areas, the book then goes on to provide hints for research in specific disciplines, as the unique traits of the individual fields compound the difficulties in interdisciplinary research. Individual chapters, written by experts in that particular area, address ten research fields in depth, disclosing the common qualities of interdisciplinary research. The study areas covered include Paleontology, Crystallography, Quaternary Research, Human Factors Engineering, Nanotechnology, Atmospheric Chemistry, Bioethics, Computational Biology, Engineering Entrepreneurship, and Machine Learning. For scientists and engineers new to their fields, as well as librarians whose responsibilities include collecting library materials for newly-emerging interdisciplinary research areas, Linda Ackerson's guide provides all that is needed to develop a successful search strategy.
Download or read book RNA Protein Interaction Protocols written by Susan R. Haynes and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: The molecular characterization of RNA and its interactions with proteins is an important and exciting area of current research. Organisms utilize a variety of RNA–protein interactions to regulate the expression of their genes. This is particularly true for eukaryotes, since newly synthesized messenger RNA must be extensively modified and transported to the cytoplasm before it can be used for protein synthesis. The realization that posttranscriptional processes are critical components of gene regulation has sparked an explosion of interest in both stable ribonucleoprotein (RNP) complexes and transient RNA–protein interactions. RNA is conformationally flexible and can adopt complex structures that provide diverse surfaces for interactions with proteins. The fact that short RNA molecules (aptamers; see Chapter 16) can be selected to bind many different types of molecules is evidence of the structural variability of RNA. RNA molecules are rarely entirely single- or double-stranded, but usually contain multiple short duplexes interrupted by single-stranded loops and bulges; in some RNAs, such as tRNAs, the short duplexes stack on each other. Further variability is generated by the presence of non-Watson-Crick base pairs, modified nucleotides, and more complex structures, such as pseudoknots and triple-strand interactions.
Download or read book Heat Shock Proteins in Veterinary Medicine and Sciences written by Alexzander A. A. Asea and published by Springer. This book was released on 2018-03-21 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This books provides up-to-date reviews on current advances of the role of HSP in veterinary medicine and research. Key basic and clinical research laboratories from major universities, veterinary hospitals and pharmaceutical companies around the world have contributed chapters that review present research activity and importantly project this field into the future. For easy readability, the book is sub divided into sections on HSP in the following aspects of Veterinary Medicine, including, I - Domestic Animals, II - Poultry, III - Aquatic and IV - Parasites. The book is a must read for heat shock protein researchers in general and specifically those involved in clinical and research in veterinary medicine.
Download or read book Protein Protein Interactions written by Krishna Mohan Poluri and published by Springer Nature. This book was released on 2021-05-19 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the fundamental aspects of protein-protein interactions (PPI), including a detailed account of the energetics and thermodynamics involved in these interactions. It also discusses a number of computational and experimental approaches for the prediction of PPI interactions and reviews their principles, advantages, drawbacks, and the recent developments. Further, it offers structural and mechanistic insights into the formation of protein-protein complexes and maps different PPIs into networks to delineate various pathways that operate at the cellular level. Lastly, it describes computational protein-protein docking techniques and discusses their implications for further experimental research. Given its scope, this book is a valuable resource for students, researchers, scientists, entrepreneurs, and medical/healthcare professionals.
