Download or read book Current Concepts in Medical Research and Practice written by Mieczyslaw Pokorski and published by Springer. This book was released on 2018-01-15 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Change is an inherent feature of all aspects of clinical practice and patient management. This book seeks to contribute to presenting novel knowledge in various fields of clinical work. The articles tackle transdisciplinary topics and focus on the underlying mechanisms of clinical disorders, their prevention and management. The themes addressed include allergy and pseudoallergy in the pediatric population, influenza-related infections and their sequelae, which continues to be a scourge in the developing world, the risk of lung cancer repeats and their management, viral hepatitis that may lead to hepatocarcinoma, respiratory consequences of diaphragmatic hernias, disorders of steroid hormone metabolism, and others. The articles bring the updated strategies, research, and best practices to improve outcomes and to deliver state-of-the-art clinical care to patients. The book will be of interest to physicians, academic scientists, and researchers who are keen in sharing the latest medical practice developments.

Download or read book Basic Science Methods for Clinical Researchers written by Morteza Jalali and published by Academic Press. This book was released on 2017-03-31 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow’s clinician scientists and future leaders in discovery science. Serves as a helpful guide for clinical researchers who lack a conventional science background Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)

Download or read book Clinical Practice Guidelines We Can Trust written by Institute of Medicine and published by National Academies Press. This book was released on 2011-06-16 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in medical, biomedical and health services research have reduced the level of uncertainty in clinical practice. Clinical practice guidelines (CPGs) complement this progress by establishing standards of care backed by strong scientific evidence. CPGs are statements that include recommendations intended to optimize patient care. These statements are informed by a systematic review of evidence and an assessment of the benefits and costs of alternative care options. Clinical Practice Guidelines We Can Trust examines the current state of clinical practice guidelines and how they can be improved to enhance healthcare quality and patient outcomes. Clinical practice guidelines now are ubiquitous in our healthcare system. The Guidelines International Network (GIN) database currently lists more than 3,700 guidelines from 39 countries. Developing guidelines presents a number of challenges including lack of transparent methodological practices, difficulty reconciling conflicting guidelines, and conflicts of interest. Clinical Practice Guidelines We Can Trust explores questions surrounding the quality of CPG development processes and the establishment of standards. It proposes eight standards for developing trustworthy clinical practice guidelines emphasizing transparency; management of conflict of interest ; systematic review-guideline development intersection; establishing evidence foundations for and rating strength of guideline recommendations; articulation of recommendations; external review; and updating. Clinical Practice Guidelines We Can Trust shows how clinical practice guidelines can enhance clinician and patient decision-making by translating complex scientific research findings into recommendations for clinical practice that are relevant to the individual patient encounter, instead of implementing a one size fits all approach to patient care. This book contains information directly related to the work of the Agency for Healthcare Research and Quality (AHRQ), as well as various Congressional staff and policymakers. It is a vital resource for medical specialty societies, disease advocacy groups, health professionals, private and international organizations that develop or use clinical practice guidelines, consumers, clinicians, and payers.

Download or read book Principles and Practice of Clinical Research written by John I. Gallin and published by Elsevier. This book was released on 2011-04-28 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers. *Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research*Delves into data management and addresses how to collect data and use it for discovery*Contains valuable, up-to-date information on how to obtain funding from the federal government

Download or read book Foundations of Clinical Research written by Leslie Gross Portney and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Draw upon the foundations necessary for finding and interpreting research evidence across all healthcare professions. Revised to reflect the most current changes in the field of clinical research in rehabilitation and medicine, you'll find a growing emphasis on evidence-based practice (EBP) as well as new vocabulary that is being integrated into research and practice across disciplines.

Download or read book Essential Concepts in Clinical Research written by Kenneth Schulz and published by Elsevier Health Sciences. This book was released on 2018-07-19 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical guide speaks to two audiences: those who read and those who conduct research. Clinicians are medical detectives by training. For each patient, they assemble clinical clues to establish causes of signs and symptoms. The task involves both clinical acumen and knowledge of medical research. This book helps guide clinicians through this detective work, by enabling them to make sense of research and to review medical literature critically. It will also be invaluable to researchers who conduct clinical research, particularly randomized controlled trials. Building on previously published, peer-reviewed articles from The Lancet, this handbook is essential for busy clinicians and active researchers interested in research methods. Written by leaders in the field of clinical research who have published extensively with authorship of hundreds of articles in medical journals. The authorship includes one of the three authors of the CONSORT guidelines for the reporting of randomized controlled trials. The book presents the essential concepts to a wide array of topics including randomized control trials, descriptive studies, cohort studies, case-control studies, bias, and screening tests. The book utilises a readable and humorous prose style, lightening what can be a difficult area for clinical readers. Derived from decades of teaching clinical research in seminar settings the book will empower clinicians to make sense of, and critically appraise, current medical research and will enable researchers to enrich the quality of their work. The updated new edition includes six new chapters: Surrogate endpoints Limitations of observational epidemiology Participant recruitment Practicalities of double-blinding Randomized trials in the context of a prospective meta-analysis Reporting studies in medical journals: CONSORT

Download or read book Medicine as a Scholarly Field An Introduction written by O.S. Miettinen and published by Springer. This book was released on 2015-08-03 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book exposes, and fills, a notable void in the educational content generally covered in modern schools of medicine. It provides an introduction to the field at large in terms of content that is relevant for each of the specialties and subspecialties of medicine; and to this end, it addresses the modern counterpart of the Hippocratic philosophy that was at the root of the genesis of modern medicine. The much-needed but still-missing introductory content for the interdisciplinary 'medical common,' provided in this book, addresses mainly the most elementary concepts and principles of medicine. Those concepts flow, hierarchically, from the essence of (health and) ill-health/illness for one and that of medicine for another, both of these critically formulated; and those principles are dictates of logic and ethics, both specific to medicine. While a modern physician is expected to be competent as a scholar in his/her particular discipline of medicine, study of this book is essential for the development of that competence -- for learning, for example, to make a tenable distinction between scientific medicine and medical science, and between knowledge-based medicine (scientific and other) and its opinion-based substitutes ('evidence-based' and other). "To me it is astonishing and to medicine actually shameful that it has taken up to year 2015 before there is a work in which the essence of medicine is described and discussed." -- J. Steurer, University of Zurich "[In this book], Miettinen beautifully elucidates the concepts and principles of knowledge-based diagnosis, and prognosis, within medicine. Now, after six decades of keen observation and study, and critical reflection on medicine and medical research, Miettinen, in this book, shares the fundamental understandings he has reached; ..." -- T. J. VanderWeele, Harvard University "The aim of this book ... is admirable. The composition of the book -- from the key concepts to logical and ethical principles -- is very clear and systematic. I am convinced that this kind of book is needed." -- I. Niiniluoto, University of Helsinki

Download or read book Critical Thinking in Clinical Research written by Felipe Fregni and published by Oxford University Press. This book was released on 2018 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critical Thinking in Clinical Research explains the fundamentals of clinical research in a case-based approach. The core concept is to combine a clear and concise transfer of information and knowledge with an engagement of the reader to develop a mastery of learning and critical thinking skills. The book addresses the main concepts of clinical research, basics of biostatistics, advanced topics in applied biostatistics, and practical aspects of clinical research, with emphasis on clinical relevance across all medical specialties.

Download or read book Acupuncture Research written by Hugh MacPherson and published by Elsevier Health Sciences. This book was released on 2007-10-12 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to set out a full range of research strategies for evaluating the clinical practice of acupuncture. Leading acupuncturists and researchers with international reputations share their expertise. They illustrate their descriptions with practical examples of what has worked and what has not. It outlines many of the key challenges in the field. These challenges relate to the nature of acupuncture and the gap between current research evidence and the actual experiences of acupuncturists in the field. By focusing the chapters on key research questions, rather than methods, the book has a user-friendly feel. Each chapter is easily accessible with brief explanations of research designs as well as vignettes of relevant past research. The book is based on a deep understanding of acupuncture, with its inherent complexity in practice, whether based on traditional principles or more modern concepts. By incorporating a more sophisticated understanding of the field, this book details a range of strategies aiming to develop the evidence base with the utmost rigour. It is the first book on acupuncture research to take this unique view, integrating the very best of evidence-based medicine with a genuine sensitivity to the discipline of acupuncture, from its traditional and holistic roots to its more modern interpretations.

Download or read book Philosophy of Medicine written by Fred Gifford and published by Elsevier. This book was released on 2011-08-23 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers a wide range of conceptual, epistemological and methodological issues in the philosophy of science raised by reflection upon medical science and practice. Several chapters examine such general meta-scientific concepts as discovery, reduction, theories and models, causal inference and scientific realism as they apply to medicine or medical science in particular. Some discuss important concepts specific to medicine (diagnosis, health, disease, brain death). A topic such as evidence, for instance, is examined at a variety of levels, from social mechanisms for guiding evidence-based reasoning such as evidence-based medicine, consensus conferences, and clinical trials, to the more abstract analysis of experimentation, inference and uncertainty. Some chapters reflect on particular domains of medicine, including psychiatry, public health, and nursing. The contributions span a broad range of detailed cases from the science and practice of medicine, as well as a broad range of intellectual approaches, from conceptual analysis to detailed examinations of particular scientific papers or historical episodes. Chapters view philosophy of medicine from quite different angles Considers substantive cases from both medical science and practice Chapters from a distinguished array of contributors

Download or read book Encyclopaedic Companion to Medical Statistics written by Brian S. Everitt and published by John Wiley & Sons. This book was released on 2011-06-20 with total page 753 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical methodology is of great importance to medical research and clinical practice. The Encyclopaedic Companion to Medical Statistics contains readable accounts of the key topics central to current research and practice. Each entry has been written by an individual chosen for both their expertise in the field and their ability to communicate statistical concepts successfully to medical researchers. Real examples from the biomedical literature and relevant illustrations feature in many entries and extensive cross–referencing signposts the reader to related entries. Key Features: Contains accounts of over 400 statistical topics central to current medical research. 80% of first edition entries updated and revised. Presents the latest techniques used at the cutting edge of medical research. Covers common errors in statistical analyses in medicine. Real examples from the biomedical literature and relevant illustrations feature throughout. Contains contributions from over 70 experts in the field. Medical researchers, researchers and practitioners in medical research and statistics will benefit greatly from this book.

Download or read book Faculty Development in the Health Professions written by Yvonne Steinert and published by Springer Science & Business Media. This book was released on 2014-01-31 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume addresses all facets of faculty development, including academic and career development, teaching improvement, research capacity building, and leadership development. In addition, it describes a multitude of ways, ranging from workshops to the workplace, in which health professionals can develop their knowledge and skills. By providing an informed and scholarly overview of faculty development, and by describing original content that has not been previously published, this book helps to ensure that research and evidence inform practice, moves the scholarly agenda forward, and promotes dialogue and debate in this evolving field. It will prove an invaluable resource for faculty development program planning, implementation and evaluation, and will help to sustain faculty members’ vitality and commitment to excellence. Kelley M. Skeff, M.D., Ph.D., May 2013: In this text, Steinert and her colleagues have provided a significant contribution to the future of faculty development. In an academic and comprehensive way, the authors have both documented past efforts in faculty development as well as provided guidance and stimuli for the future. The scholarly and well-referenced chapters provide a compendium of methods previously used while emphasizing the expanding areas deserving work. Moreover, the writers consistently elucidate the faculty development process by highlighting the theoretical underpinnings of faculty development and the research conducted. Thus, the book provides an important resource for two major groups, current providers and researchers in faculty development as well as those desiring to enter the field. Both groups of readers can benefit from a reading of the entire book or by delving into their major area of interest and passion. In so doing, they will better understand our successes and our limitations in this emerging field. Faculty development in the health professions has now received attention for 6 decades. Yet, dedicated faculty members trying to address the challenges in medical education and the health care delivery system do not have all the assistance they need to achieve their goals. This book provides a valuable resource towards that end.

Download or read book How to Practice Academic Medicine and Publish from Developing Countries written by Samiran Nundy and published by Springer Nature. This book was released on 2021-10-23 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an open access book. The book provides an overview of the state of research in developing countries – Africa, Latin America, and Asia (especially India) and why research and publications are important in these regions. It addresses budding but struggling academics in low and middle-income countries. It is written mainly by senior colleagues who have experienced and recognized the challenges with design, documentation, and publication of health research in the developing world. The book includes short chapters providing insight into planning research at the undergraduate or postgraduate level, issues related to research ethics, and conduct of clinical trials. It also serves as a guide towards establishing a research question and research methodology. It covers important concepts such as writing a paper, the submission process, dealing with rejection and revisions, and covers additional topics such as planning lectures and presentations. The book will be useful for graduates, postgraduates, teachers as well as physicians and practitioners all over the developing world who are interested in academic medicine and wish to do medical research.

Download or read book Research for Advanced Practice Nurses Second Edition written by Magdalena A. Mateo, PhD, RN, FAAN and published by Springer Publishing Company. This book was released on 2013-10-28 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book should provide graduate nursing students with the knowledge to evaluate research evidence and use it in practice. With the increasing focus on EBP, this book should serve as a useful resource." Score: 100, 5 stars.--Doody's "This book would be useful for both graduate nursing students and practicing nurses."--Doody's Medical Reviews The second edition of this award-winning reference on formulating, achieving, and sustaining evidence-based practice (EBP) through clinical research updates all prior content and includes two new chapters on establishing and sustaining an evidence-based practice and environment, and how a research question drives the selection of research design, measurement, and analysis. Also featured are cutting-edge discussions of translational science and interprofessional research plus the contributions of several new authors. Designed for use by graduate students, clinical administrators, and managers and in DNP programs and in-service education, the text offers practical methods to translate evidence into practice by effectively using and appraising clinical studies. It presents research concepts in a clear, conversational tone and addresses the most current knowledge about how nurses can learn to formulate and achieve EBP as clinicians. From a single study to a meta-analysis, EBP concepts related to patient care are integrated throughout. Clinically relevant examples present ways students and staff can apply knowledge to daily clinical practice through the development, implementation, and evaluation of clinical protocols. Text boxes and web references reinforce information. Taken together, the content of the Second Edition will help the nursing profession in its move toward the forefront of institutional management, research, policy decisions, and ethical considerationsóall to enhance safe patient care and health. The book also includes interactive PDF with fill-in, reusable templates, and is available in enhanced eBook format that includes audio/video Q & A. New to the Second Edition: Presents new content on translational science and inter-professional research. Updates all content from the first edition. Includes two new chapters on establishing and sustaining EBT and how a research question drives the selection of a research design, measurement and analysis. Presents the contributions of several new authors. Features psychosocial and physical data collection and analysis methods. Includes guidelines on evaluating research articles, including ethical components. Suggests strategies for establishing and sustaining an organizational evidence-based practice. Presents primary ways of evaluating cost as a dimension of evidence-based practice. Offers appendices with evidence-based practice activities and protocols, and a resource list of relevant websites. Features interactive PDF with fill-in, reusable templates. Available as enhanced eBook that includes audio/video Q & A

Download or read book Finding What Works in Health Care written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-20 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.

Download or read book Designing Clinical Research written by Stephen B. Hulley and published by Lippincott Williams & Wilkins. This book was released on 2011-11-30 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designing Clinical Research sets the standard for providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology—including molecular and genetic clinical research—and offers an updated syllabus for conducting a clinical research workshop. Emphasis is on common sense as the main ingredient of good science. The book explains how to choose well-focused research questions and details the steps through all the elements of study design, data collection, quality assurance, and basic grant-writing. All chapters have been thoroughly revised, updated, and made more user-friendly.

Download or read book Issues in Clinical Medicine Research and Practice 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 1212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Clinical Medicine Research and Practice: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Clinical Medicine Research and Practice. The editors have built Issues in Clinical Medicine Research and Practice: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Clinical Medicine Research and Practice in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Clinical Medicine Research and Practice: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.