Download or read book Crossroads Between Innate and Adaptive Immunity IV written by Peter D. Katsikis and published by Springer Science & Business Media. This book was released on 2013-03-01 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents a collection of reviews derived from work presented at the Aegean Conference: “4th Crossroads between innate and adaptive immunity”. This meeting was the fourth in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity. The importance of the crosstalk between innate immunity and the adaptive immune response has only recently started to be appreciated. Although it is well recognized that dendritic cells, NK cells, NK-T cells and T cells are all critical for the host response to pathogens, the respective fields that study the biology of these immune cells tend to exist in parallel worlds with minimum exchange of information and ideas. This fragmentation hinders the integration of these fields towards a unified theory of host response. The Aegean Conference “Crossroads between Innate and Adaptive Immunity” brought together leading international scientists and experts to address critical areas of Innate and Adaptive immunity something necessary for the development of more efficient scientific exchange and crosspollination between these fields. This conference attracted scientists from all over the world to discuss their latest findings on the various aspects of Innate and Adaptive immunity. The conference had limited participation and a scientific and social program that maximized scientific interchange through lecture presentations, poster sessions and informal discussions.
Download or read book Crossroads between Innate and Adaptive Immunity written by Peter D. Katsikis and published by Springer Science & Business Media. This book was released on 2007-12-08 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This compilation presents mini-reviews derived from work presented at the Aegean Conference: "First Crossroads between Innate and Adaptive Immunity," which occurred in October, 2005 at the Hilton Conference Center on the island of Rhodes, Greece. The conference included sessions dedicated to host recognition of and response to pathogens, innate immune networks, antigen presentation, and adaptive immune responses, each headlined by a leading scientist.
Download or read book Crossroads between Innate and Adaptive Immunity III written by Bali Pulendran and published by Springer Science & Business Media. This book was released on 2011-08-19 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents a collection of reviews derived from work presented at the Aegean Conference: “3rd Crossroads between innate and adaptive immunity” which occurred during September 27 - October 2, 2009 at the Minoa Palace Conference Center in Chania, Crete, Greece. This meeting was the third in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity. The various facets of the innate response, including dendritic cells, T cells, B cells, NK cells, NK-T cells and the complement cascade during the host response to pathogens and tumors is only now starting to be elucidated. The respective fields that focus on these immune cells and molecules have tended to be relatively compartmentalized, and yet emerging evidence points to the interconnectedness of these facets in coordinating the innate response, and its subsequent impact on the adaptive response. The goal of this conference was to initiate cross-talk between these diverse immunological fields, and promote and facilitate discussion on the interactions between the innate immune response and the adaptive immune response and ultimately facilitate collaboration between these areas of study. Following on the footsteps of the outstanding success of its precursors, the “3rd Crossroads between Innate and Adaptive Immunity” Aegean Conference was highly successful in bringing together and connecting scientists and experts from around the world to address critical areas of Innate and Adaptive immunity.
Download or read book Crossroads Between Innate and Adaptive Immunity V written by Stephen P. Schoenberger and published by Springer. This book was released on 2015-08-31 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents a collection of reviews derived from work presented at the Aegean Conference: “5th Crossroads Between Innate and Adaptive Immunity”. This meeting was the fifth in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity. The importance of the crosstalk between innate immunity and the adaptive immune response has only recently started to be appreciated. Although it is well recognized that dendritic cells, NK cells, NK-T cells and T cells are all critical for the host response to pathogens, the respective fields that study the biology of these immune cells tend to exist in parallel worlds with minimum exchange of information and ideas. This fragmentation hinders the integration of these fields towards a unified theory of host response. The Aegean Conference “Crossroads between Innate and Adaptive Immunity” brought together leading international scientists and experts to address critical areas of Innate and Adaptive Immunity, a necessary step in the development of more efficient scientific exchange and crosspollination between these fields. This conference attracted scientists from all over the world to discuss their latest findings on the various aspects of Innate and Adaptive Immunity, and maximized scientific interchange through lecture presentations, poster sessions and informal discussions.
Download or read book Crossroads between Innate and Adaptive Immunity II written by Stephen P. Schoenberger and published by Springer Science & Business Media. This book was released on 2008-12-10 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aegean Conferences is an independent, nonprofit, educational organization directed and managed by the scientific community. The board is made up of nine researchers/scientists in various disciplines from Harvard, Brown, University of Pennsylvania, UCSD, Princeton, Biovista and the Foundation for Biomedical Research Academy of Athens. The board both invites and approves unsolicited proposals for Conferences in all fields of Science, Engineering, Arts, and Humanities. The purpose of the Conferences is to bring together individuals with common interests to examine the emerging and most advanced aspects of their particular field. This volume will include mini-reviews derived from work to be presented at the Aegean Conference: Second Crossroads between Innate and Adaptive Immunity, in Crete, Greece, June 17-22, 2007. This meeting is designed to serve as a forum to discuss the most recent progress in complement research as it pertains to human disease pathogenesis and therapeutics. The rapid pace of development in complement basic research and the advent and application of new experimental approaches in this field have now allowed us to take an integrated view of the in vivo biology of the complement system. The availability of new reagents (e.g. synthetic and recombinant inhibitors) and animal models (e.g. transgenic and knockout mice) has enabled us to address, in an in vivo setting, its involvement in various pathophysiological conditions. Such studies are shedding new light on the pathogenetic mechanism of complement-related diseases such as autoimmune diseases and inflammatory tissue damage as well as defining new areas of high interest such as the developmental biology of complement. They also provide the basis for developing new therapeutic strategies for these diseases through manipulation of in vivo complement activity. This volume will serve as a resource where the latest development in these specific areas will be discussed in a more focused and detailed manner.
Download or read book Janeway s Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Download or read book Advances in Immunology written by and published by Academic Press. This book was released on 2018-05-03 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Immunology, Volume 138, the latest in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this release including chapters on Eosinophil Development, Disease Involvement, and Therapeutic Suppression, Immunoglobulin A responses to the microbiota, Unexpected roles for intracellular complement in the regulation of TH1 responses, Magnesium in T cell signaling, and immunological synapse and T cell signaling. Contains contributions from leading authorities in immunology Informs and updates on the latest developments in the field of immunology
Download or read book Ecological Genomics written by Christian R. Landry and published by Springer Science & Business Media. This book was released on 2013-11-25 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers in the field of ecological genomics aim to determine how a genome or a population of genomes interacts with its environment across ecological and evolutionary timescales. Ecological genomics is trans-disciplinary by nature. Ecologists have turned to genomics to be able to elucidate the mechanistic bases of the biodiversity their research tries to understand. Genomicists have turned to ecology in order to better explain the functional cellular and molecular variation they observed in their model organisms. We provide an advanced-level book that covers this recent research and proposes future development for this field. A synthesis of the field of ecological genomics emerges from this volume. Ecological Genomics covers a wide array of organisms (microbes, plants and animals) in order to be able to identify central concepts that motivate and derive from recent investigations in different branches of the tree of life. Ecological Genomics covers 3 fields of research that have most benefited from the recent technological and conceptual developments in the field of ecological genomics: the study of life-history evolution and its impact of genome architectures; the study of the genomic bases of phenotypic plasticity and the study of the genomic bases of adaptation and speciation.
Download or read book Viral Entry into Host Cells written by Stefan Pöhlmann and published by Springer Science & Business Media. This book was released on 2013-07-24 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: For a virus to invade a host cell it needs to penetrate the physical barrier imposed by the plasma membrane. Viruses have evolved specialized surface proteins to meet this challenge. These proteins facilitate delivery of the viral genetic information into the host cell by either fusing the viral envelope with a host cell membrane or by forming membrane pores. Membrane fusion and pore formation critically depend on the engagement of host cell receptors and receptor choice is a key determinant of viral tropism. The multi-faceted interplay between viral and cellular factors during virus entry is a fascinating field of study, which can provide important insight into viral pathogenesis and define new targets for intervention. This book provides a comprehensive overview of this exciting field of research.
Download or read book barrel Channel Proteins as Tools in Nanotechnology written by Marco Fioroni and published by Springer Science & Business Media. This book was released on 2013-11-04 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: ß-barrel outer membrane channel proteins (OMP) are useful as robust and flexible models or components in nanotechnology. Over the last decade biotechnological techniques allowed to expand the natural characteristics of OMPs by modifying their geometry and properties. The present book is oriented towards a broad group of readers including graduate students and advanced researchers. It gives a general introduction to the field of OMP based nano-component development as well as the state of the art of the involved research. On the example of the E. coli FhuA the transformation of an OMP into a tailored nano-channel will be outlined. An exhaustive description of the scientific strategy, including protein selection, analytical methods and “in-silico” tools to support the planning of protein modifications for a targeted application, consideration on the production of a custom made OMP, and an overview on technological applications including membrane/polymersome technology, will be provided.
Download or read book Cellular and Molecular Control of Neuronal Migration written by Laurent Nguyen and published by Springer Science & Business Media. This book was released on 2013-11-18 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Molecular Control of Neuronal Migration provides an up-to-date collection of reviews on the molecular and cellular principles of neuronal migration in the mammalian brain. Over the last decades a rich catalogue of signaling molecules controlling neuronal migration has been compiled, and within this book an international panel of experts provides up-to-date discussions of the state of knowledge how these distinct signaling pathways regulate various aspects of neuronal migration. This book introduces the reader to the latest discoveries and concepts of neuronal migration enabled through the application of most sophisticated methods and cutting edge experimental approaches. Cellular and Molecular Control of Neuronal Migration also provides an update on the underlying cellular and molecular basis of neurodevelopmental migration disorders in human patients for all interested neuroscientists and clinicians.
Download or read book Innate Lymphoid Cells in Cancer Friends or Foes written by Nicolas Jacquelot and published by Frontiers Media SA. This book was released on 2022-01-10 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Principles of Immunopharmacology written by Frans P. Nijkamp and published by Springer Science & Business Media. This book was released on 2011-09-01 with total page 743 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a unique support in gaining essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The first section of the book, covering a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts. The second section on immunodiagnostics has been further expanded to describe widely used molecular techniques and is followed by a systematic coverage of drugs affecting the immune system, revised to cover recent developments. The book concludes with a chapter on immunotoxicology. This third edition continues the unique format dealing with four related topics in a single volume, obviating the need to refer to several different textbooks. New aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first edition.
Download or read book Antibody Fc written by Margaret Ackerman and published by Academic Press. This book was released on 2013-08-06 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibody Fc is the first single text to synthesize the literature on the mechanisms underlying the dramatic variability of antibodies to influence the immune response. The book demonstrates the importance of the Fc domain, including protective mechanisms, effector cell types, genetic data, and variability in Fc domain function. This volume is a critical single-source reference for researchers in vaccine discovery, immunologists, microbiologists, oncologists and protein engineers as well as graduate students in immunology and vaccinology. Antibodies represent the correlate of protection for numerous vaccines and are the most rapidly growing class of drugs, with applications ranging from cancer and infectious disease to autoimmunity. Researchers have long understood the variable domain of antibodies, which are responsible for antigen recognition, and can provide protection by blocking the function of their target antigen. However, recent developments in our understanding of the protection mediated by antibodies have highlighted the critical nature of the antibody constant, or Fc domain, in the biological activity of antibodies. The Fc domain allows antibodies to link the adaptive and innate immune systems, providing specificity to a wide range of innate effector cells. In addition, they provide a feedback loop to regulate the character of the immune response via interactions with B cells and antigen-presenting cells. - Clarifies the different mechanisms of IgG activity at the level of the different model systems used, including human genetic, mouse, and in vitro - Covers the role of antibodies in cancer, infectious disease, and autoimmunity and in the setting of monoclonal antibody therapy as well as naturally raised antibodies - Color illustrations enhance explanations of the immune system
Download or read book Trends in Fisheries and Aquatic Animal Health written by Panagiotis Berillis and published by Bentham Science Publishers. This book was released on 2017-11-11 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fish and other seafood have always been considered as an important part of human diet and have also long been recognized as a health-promoting food for human nutrition. However, managing aquatic food resources remains a challenge as the human population is expanding and overfishing poses a threat to fishing reserves in several areas. Aquaculture is the alternative solution for food production from the sea. According to the FAO, aquaculture is probably the fastest growing food-producing sector and can be a sustainable solution for fish production. In order to maximize marine food production and achieving sustainable management of the aquatic environment, knowledge about aspects of fisheries and aquatic animal health is very important. Trends in Fisheries and Aquatic Animal Health covers some basic and applied topics in fishery management and fish health with a focus on European regions. The textbook is a combination of reviews and research articles. Topics covered in the book include challenges in fishery management, environmental impacts on fisheries, fish health (pharmacology, histopathology, stress response), telemetry techniques in fisheries research, and specific case studies of regional marine species in localized fisheries. This textbook is a useful resource for graduates and professionals involved in advanced training courses for aquaculture and fishery management.
Download or read book Essential Immunology for Surgeons written by Oleg Eremin and published by OUP Oxford. This book was released on 2011-04-28 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been a huge increase in the knowledge and understanding of the immunological processes involved in surgical practice in recent years. Anaesthesiologists and intensive care physicians are increasingly recognising the significant derangements of immune function in the critically ill patient and the possible therapeutic approaches to manage such patients (including new approaches in transplantation rejections, novel vaccination strategies in cancer treatment, as well as a better understanding of the beneficial effects of standard chemotherapy). Written by recognised experts in their field from both the UK and the US, and extensively referenced for further reading, Essential Immunology for Surgeons provides a concise, up-to-date, and readable account of immunology in general and its translation into key areas of clinical practice. It provides the necessary foundation for a critical understanding of this essential and rapidly expanding area of biological science that underpins and explains the modern concepts of a range of diseases and conditions, encompassing autoimmunity, infection, trauma, cancer, nutrition, organ transplantation, and various forms of therapy. Previously published as Immunological Basis for Surgical Science and Practice, this fully-updated textbook is aimed predominantly at the surgical trainee, but will also be of value to undergraduate and postgraduate clinicians of any discipline who wish to have a better understanding and knowledge of the subject, as well as to researchers studying the various core topics discussed in the book.
Download or read book Antibody Fc written by Luisa Martinez-Pomares and published by Elsevier Inc. Chapters. This book was released on 2013-08-06 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: This chapter offers an overview of the basic biology of phagocytes, macrophages, dendritic cells, and neutrophils and how it is affected by receptors for the Fc portion of antibodies (FcRs), particularly FcγRs. We focus on important processes such as phagocytosis and antigen presentation but it must be considered that these occur within the context of inflammation, where the complementary roles of the different phagocyte populations are clearly exposed. For this purpose, a brief description of the inflammatory response has also been included. Finally, research in innate immunity is coming to terms with the wide range of responses that can be achieved by selective engagement of pattern-recognition receptors, and we provide examples of how receptors not normally associated with responses to immunocomplexes modulate cellular activation mediated by FcRs.
