Download or read book Creating a Tradition of Biomedical Research written by Darwin H. Stapleton and published by Rockefeller Univ. Press. This book was released on 2004 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advancing the Nation s Health Needs written by National Research Council and published by National Academies Press. This book was released on 2005-08-13 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report is the twelfth assessment of the National Institutes of Health National Research Service Awards program. The research training needs of the country in basic biomedical, clinical, and behavioral and social sciences are considered. Also included are the training needs of oral health, nursing, and health services research. The report has been broadly constructed to take into account the rapidly evolving national and international health care needs. The past and present are analyzed, and predictions with regard to future needs are presented.
Download or read book Rethinking Health Care Ethics written by Stephen Scher and published by Springer. This book was released on 2018-08-02 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this open access book is to develop an approach to clinical health care ethics that is more accessible to, and usable by, health professionals than the now-dominant approaches that focus, for example, on the application of ethical principles. The book elaborates the view that health professionals have the emotional and intellectual resources to discuss and address ethical issues in clinical health care without needing to rely on the expertise of bioethicists. The early chapters review the history of bioethics and explain how academics from outside health care came to dominate the field of health care ethics, both in professional schools and in clinical health care. The middle chapters elaborate a series of concepts, drawn from philosophy and the social sciences, that set the stage for developing a framework that builds upon the individual moral experience of health professionals, that explains the discontinuities between the demands of bioethics and the experience and perceptions of health professionals, and that enables the articulation of a full theory of clinical ethics with clinicians themselves as the foundation. Against that background, the first of three chapters on professional education presents a general framework for teaching clinical ethics; the second discusses how to integrate ethics into formal health care curricula; and the third addresses the opportunities for teaching available in clinical settings. The final chapter, "Empowering Clinicians", brings together the various dimensions of the argument and anticipates potential questions about the framework developed in earlier chapters.
Download or read book Evidence Ethos and Experiment written by P. Wenzel Geissler and published by Berghahn Books. This book was released on 2011-09-30 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical research has been central to biomedicine in Africa for over a century, and Africa, along with other tropical areas, has been crucial to the development of medical science. At present, study populations in Africa participate in an increasing number of medical research projects and clinical trials, run by both public institutions and private companies. Global debates about the politics and ethics of this research are growing and local concerns are prompting calls for social studies of the "trial communities" produced by this scientific work. Drawing on rich, ethnographic and historiographic material, this volume represents the emergent field of anthropological inquiry that links Africanist ethnography to recent concerns with science, the state, and the culture of late capitalism in Africa.
Download or read book Large Scale Biomedical Science written by National Research Council and published by National Academies Press. This book was released on 2003-07-19 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nature of biomedical research has been evolving in recent years. Technological advances that make it easier to study the vast complexity of biological systems have led to the initiation of projects with a larger scale and scope. In many cases, these large-scale analyses may be the most efficient and effective way to extract functional information from complex biological systems. Large-Scale Biomedical Science: Exploring Strategies for Research looks at the role of these new large-scale projects in the biomedical sciences. Though written by the National Academies' Cancer Policy Board, this book addresses implications of large-scale science extending far beyond cancer research. It also identifies obstacles to the implementation of these projects, and makes recommendations to improve the process. The ultimate goal of biomedical research is to advance knowledge and provide useful innovations to society. Determining the best and most efficient method for accomplishing that goal, however, is a continuing and evolving challenge. The recommendations presented in Large-Scale Biomedical Science are intended to facilitate a more open, inclusive, and accountable approach to large-scale biomedical research, which in turn will maximize progress in understanding and controlling human disease.
Download or read book The Belmont Report written by United States. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research and published by . This book was released on 1978 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toward Precision Medicine written by National Research Council and published by National Academies Press. This book was released on 2012-01-16 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.
Download or read book A History of the Development of Alternatives to Animals in Research and Testing written by John Parascandola and published by Purdue University Press. This book was released on 2024-07-15 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: Growing public interest in animal welfare issues in recent decades has prompted increased attention to the efforts to develop alternative, nonanimal methods for use in biomedical research and product testing. In A History of the Development of Alternatives to Animals in Research and Testing, the first book-length study of the subject, John Parascandola traces the history of the concept of alternatives to the use of animals in research and testing in Britain and the United States from its beginnings until it had become firmly established in the scientific and animal protection communities by the end of the 1980s. This account of the history of alternatives is set within the context of developments within science, animal welfare, and politics. The book covers the key role played by animal welfare advocates in promoting alternatives, the initial resistance to alternatives on the part of many in the scientific community, the opportunity provided by alternatives for compromise and cooperation between these two groups, and the dominance of the “Three Rs”—reduction, refinement, and replacement.
Download or read book A Contagious Cause written by Robin Wolfe Scheffler and published by University of Chicago Press. This book was released on 2019-06-15 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Is cancer a contagious disease? In the late nineteenth century this idea, and attending efforts to identify a cancer “germ,” inspired fear and ignited controversy. Yet speculation that cancer might be contagious also contained a kernel of hope that the strategies used against infectious diseases, especially vaccination, might be able to subdue this dread disease. Today, nearly one in six cancers are thought to have an infectious cause, but the path to that understanding was twisting and turbulent. ? A Contagious Cause is the first book to trace the century-long hunt for a human cancer virus in America, an effort whose scale exceeded that of the Human Genome Project. The government’s campaign merged the worlds of molecular biology, public health, and military planning in the name of translating laboratory discoveries into useful medical therapies. However, its expansion into biomedical research sparked fierce conflict. Many biologists dismissed the suggestion that research should be planned and the idea of curing cancer by a vaccine or any other means as unrealistic, if not dangerous. Although the American hunt was ultimately fruitless, this effort nonetheless profoundly shaped our understanding of life at its most fundamental levels. A Contagious Cause links laboratory and legislature as has rarely been done before, creating a new chapter in the histories of science and American politics.
Download or read book Humane Professions written by Rob Boddice and published by Cambridge University Press. This book was released on 2021-01-28 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rob Boddice explores the transnational defence of medical experimentation in the nineteenth and early twentieth centuries.
Download or read book Legal and Ethical Regulation of Biomedical Research in Developing Countries written by Remigius N. Nwabueze and published by Routledge. This book was released on 2016-04-22 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been a rapid increase in the pace and scope of international collaborative research in developing countries in recent years. This study argues that whilst ethical regulation of biomedical research in Africa and other developing countries has attracted global attention, legal liability issues, such as the application of common law rules and the development of legally enforceable regulations, have been neglected. It examines some of the major research scandals in Africa and suggests a new ethical framework against which clinical trials could be conducted. The development of research guidelines in Uganda, Tanzania, Malawi and Nigeria are also examined as well as the role of ethics committees. Providing a detailed analysis of the law of negligence and its application to research ethics committees and their members, common law and constitutional forms of action and potential negligence claims, the book concludes by suggesting new protocols and frameworks, improved regulation and litigation. This book will be a valuable guide for students, researchers, and policy-makers with an interest in medical law and ethics, bioethics, customary law in Africa and regulation in developing countries.
Download or read book Cancer Associated Viruses written by Erle S. Robertson and published by Springer Science & Business Media. This book was released on 2012-02-14 with total page 869 pages. Available in PDF, EPUB and Kindle. Book excerpt: The acknowledgment that viruses are potent biological factors in driving many cancers have seen a dramatic upsurge in recent years in large part to the success of the human papilloma virus vaccine against invasive cervical carcinomas and followed by the awarding of the noble prize in medicine in 2008 to Dr. Harald zurHausen who identified the link between papilloma virus and cervical cancers. Over the last few years there have been some volumes addressing different aspects of viruses and cancers and to some extent focusing on the DNA viruses, more specifically the human DNA viruses. This proposed volume will attempt to review and address the major gaps in current knowledge in DNA viruses as well as RNA viruses bringing a historical perspective of where studies began to a more recent molecular approach and vaccine successes in tumor viruses. We will also cover other known oncogenic viruses associated cancers in other mammals in addition to humans.
Download or read book Biomedicine in the Twentieth Century Practices Policies and Politics written by C. Hannaway and published by IOS Press. This book was released on 2008-02-11 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedicine in the Twentieth Century: Practices, Policies, and Politics is a testimony to the growing interest of scholars in the development of the biomedical sciences in the twentieth century and to the number of historians, social scientists and health policy analysts now working on the subject. The book is comprised of essays by noted historians and social scientists that offer insights on a range of subjects that should be a significant stimulus for further historical investigation. It details the NIH’s practices, policies and politics on a variety of fronts, including the development of the intramural program, the National Institute of Mental Health and mental health policy, the politics and funding of heart transplantation and the initial focus of the National Cancer Institute. Comparisons can be made with the development of other American and British institutions involved in medical research, such as the Rockefeller Institute and the Medical Research Council. Discussions of the larger scientific and social context of United States’ federal support for research, the role of lay institutions in federal funding of virus research, the consequences of technology transfer and patenting, the effects of vaccine and drug development and the environment of research discoveries all offer new insights and suggest questions for further exploration.
Download or read book From Medical Chemistry to Biochemistry written by Robert E. Kohler and published by Cambridge University Press. This book was released on 1982-05-31 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This penetrating case study of institution building and entrepreneurship in science shows how a minor medical speciality evolved into a large and powerful academic discipline. Drawing extensively on little-used archival sources, the author analyses in detail how biomedical science became a central part of medical training and practice. The book shows how biochemistry was defined as a distinct discipline by the programmatic vision of individual biochemists and of patrons and competitors in related disciplines. It shows how discipline builders used research programmes as strategies that they adapted to the opportunities offered by changing educational markets and national medical reform movements in the United States, Britain and Germany. The author argues that the priorities and styles of various departments and schools of biochemistry reflect systematic social relationships between that discipline and biology, chemistry and medicine. Science is shaped by its service roles in particular local contexts: This is the central theme. The author's view of the political economy of modern science will be of interest to historians and social scientists, scientific and medical practitioners, and anyone interested in the ecology of knowledge in scientific institutions and professions.
Download or read book Reproducibility in Biomedical Research written by Erwin B. Montgomery and published by Academic Press. This book was released on 2019-03-14 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reproducibility in Biomedical Research: Epistemological and Statistical Problems explores the ideas and conundrums inherent in scientific research. It explores factors of reproducibility, including logic, distinguishing productive from unproductive irreproducibility, the scientific method, and the use of statistics. In multiple examples and six detailed case studies, the book demonstrates the misuse of logic resulting in unproductive irreproducibility, allowing researchers to develop their own logic and planning abilities. Biomedical researchers, clinicians, administrators of scientific institutions and funding agencies, journal editors, philosophers of science and medicine will find the arguments and explorations a valuable addition to their libraries. Considers the meaning and purpose of reproducibility to help design research Reviews famous case studies of alleged irreproducibility to determine if these could be reproducible Provides a theoretical aspect to practical issues surrounding research design and conduct
Download or read book Malignant Growth written by Alan I Marcus and published by University of Alabama Press. This book was released on 2018-04-10 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this accessible history of science and medicine, Marcus exposes the complex story of the efforts made from 1875 through 1915 to first conquer and, failing that, to control cancer--a dual approach that remains in force to this day. He reveals the messiness of real-time scientific research, tracing the repeated lurches of promise, discoveries of hope, and the inevitable despair that always followed. Other barriers existed to the research, such as inconsistency in test standards and inter-laboratory competition and mistrust. Researchers approached cancer from such disparate specialties as clinical medicine, zoology, botany, chemistry, nutrition, bacteriology, pathology, and microbiology. Although they came from diverse fields, each steadfastly maintained that cancer operated in an analogous fashion to other bacteriological diseases.
