Download or read book Advances in Structure and Activity Relationship of Coumarin Derivatives written by Santhosh Penta and published by Academic Press. This book was released on 2015-08-07 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Structure and Activity Relationship of Coumarin Derivatives covers the structural behavior of various coumarin derivatives for various potential pharmaceutical applications. Based on substitution targeted for active sites, the book takes a rational approach for designing new and specific potent drugs, optimizing existing ones, and developing novel reactions. This focused primer describes the chemical structure and activity of coumarin derivatives to explore the effects of different substituents at specific positions, and their properties for effective bioactivity. - Accessible and current coverage of coumarin derivatives from structure to potential applications - Application of SAR technology to predict bioactivity of the derivatives based on its chemical structure - Information for researchers in medicinal chemistry, pharmaceutical sciences, and related fields

Download or read book Coumarins written by Richard O'Kennedy and published by Wiley. This book was released on 1997-04-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coumarins: Biology, Applications and Mode of Action predominantly focuses on the parent compound, coumarin, and its main metabolite in humans, 7-hydroxycoumarin. It describes in detail every facet of these compounds including history, toxicology, chemistry, metabolism, analysis, clinical, veterinary and other applications, their roles as immunomodulatory agents and speculates on their mode of action.

Download or read book Coumarin and Its Derivatives written by Maria João Matos and published by Mdpi AG. This book was released on 2021-12-29 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coumarins are widely distributed in nature and can be found in a large number of naturally occurring and synthetic bioactive molecules. The unique and versatile oxygen-containing heterocyclic structure makes them a privileged scaffold in Medicinal Chemistry. Many coumarin derivatives have been extracted from natural sources, designed, synthetized, and evaluated on different pharmacological targets. In addition, coumarin-based ion receptors, fluorescent probes, and biological stains are growing quickly and have extensive applications to monitor timely enzyme activity, complex biological events, as well as accurate pharmacological and pharmacokinetic properties in living cells. The extraction, synthesis, and biological evaluation of coumarins have become extremely attractive and rapidly developing topics. A large number of research and review papers have compiled information on this important family of compounds in 2020. Research articles, reviews, communications, and concept papers focused on the multidisciplinary profile of coumarins, highlighting natural sources, most recent synthetic pathways, along with the main biological applications and theoretical studies, were the main focus of this book. The huge and growing range of applications of coumarins described in this book is a demonstration of the potential of this family of compounds in Organic Chemistry, Medicinal Chemistry, and different sciences related to the study of natural products. This book includes 23 articles: 17 original papers and six review papers.

Download or read book The Introduction of Coumarin written by Jigar L P and published by Blue Rose Publishers. This book was released on with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Coumarin is a well known naturally occurring organic compound. It is utilised in various fields like medicine, dyes, and fluorescence. Around the world more and more research is being conducted on this compound due to its properties. This book is introduced to give concise information for initial knowledge on coumarin. The salient features of this book are as under: Complete introduction of coumarin through important references from around the world. First time detailed presentation of isolation and natural occurrence of coumarin in a detailed chapter. Proper citation of references in each chapter which helps researcher to design their work more easily. Chapters include formats to help researchers get ideas for development of their work. Each chapter provides specific information aimed clearly at students and researchers. Special Feature: An additional chapter on Organic Synthesis Approach which helps to design routes of synthesis via retro analysis."

Download or read book The Natural Coumarins written by Robert Douglas Hutton Murray and published by Chichester ; Toronto : Wiley. This book was released on 1982 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Coumarin Anticoagulant Research Progress written by Joseph P. Edardes and published by Nova Publishers. This book was released on 2008 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Warfarin (also known under the brand names of Coumadin, Jantoven, Marevan, and Waran) is an anticoagulant medication that is administered orally or, very rarely, by injection. It is used for the prophylaxis of thrombosis and embolism in many disorders. Its activity has to be monitored by frequent blood testing for the international normalised ratio (INR). It is named for the Wisconsin Alumni Research Foundation. Warfarin is a synthetic derivative of coumarin, a chemical found naturally in many plants, notably woodruff (Galium odoratum, Rubiaceae), and at lower levels in liquorice, lavender and various other species. Warfarin was originally developed as a rat poison; however, more modern poisons are much more potent and toxic (e.g., brodifacoum). Warfarin and contemporary rodenticides belong to the same class of drugs (coumarins) and both decrease blood coagulation by interfering with vitamin K metabolism. For this reason, drugs in this class are also referred to as vitamin K antagonists.

Download or read book Phytochemicals written by Venketeshwer Rao and published by BoD – Books on Demand. This book was released on 2015-09-30 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global dietary recommendations emphasize the consumption of plant-based foods for the prevention and management of chronic diseases. Plants contain many biologically active compounds referred to as phytochemicals or functional ingredients. These compounds play an important role in human health. Prior to establishing the safety and health benefits of these compounds, they must first be isolated, purified, and their physico-chemical properties established. Once identified, their mechanisms of actions are studied. The chapters are arranged in the order from isolation, purification and identification to in vivo and clinical studies, there by covering not only the analytical procedures used but also their nutraceutical and therapeutic properties.

Download or read book Sclerotherapy written by Mitchel P. Goldman and published by Mosby. This book was released on 2007 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 4th edition continues to provide the comprehensive coverage you've come to expect, of all aspects of sclerotherapy and surgical treatment of varicose and telangiectatic leg veins. It has been completely revised, with all figures and drawings now in full color. Packed with everything you need to know about sclerotherapy, this classic reference provides extensive discussions of the latest techniques, solutions, and possible complications. The practical instructions contained in the book are now complimented by a professionally produced DVD which demonstrates all of the techniques.

Download or read book Coumarins and Indandiones Advances in Research and Application 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coumarins and Indandiones—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Coumarins and Indandiones in a concise format. The editors have built Coumarins and Indandiones—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Coumarins and Indandiones in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Coumarins and Indandiones—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Fortschritte Der Chemie Organischer Naturstoffe written by László Zechmeister and published by . This book was released on 1938 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Herbal Biomolecules in Healthcare Applications written by Subhash C. Mandal and published by Academic Press. This book was released on 2021-10-05 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: Herbal Biomolecules in Healthcare Applications presents extensive detailed information on all the vital principles, basics and fundamental aspects of multiple herbal biomolecules in the healthcare industry. This book examines important herbal biomolecules including alkaloids, glycosides, flavonoids, anthraquinones, steroids, polysaccharides, tannins and polyphenolic compounds, terpenes, fats and waxes, proteins and peptides, and vitamins. These herbal biomacromolecules are responsible for different bioactivities as well as pharmacological potentials. A systematic understanding of the extraction, purification, characterization, applications of these herbal biomolecules and their derivatives in healthcare fields is developed in this comprehensive book. Chapters explore the key topics along with an emphasis on recent research and developments in healthcare fields by leading experts. They include updated literature review of the relevant key topics, good quality illustrations, chemical structures, flow charts, well-organized tables and case studies. Herbal Biomolecules in Healthcare Applications will be useful for researchers working on natural products and biomolecules with bioactivity and nutraceutical properties. Professionals specializing in scientific areas such as biochemistry, pharmacology, analytical chemistry, organic chemistry, clinics, or engineering focused on bioactive natural products will find this book useful. - Provides a study of different type of biomolecules from herbal extracts and their bioactivities as well as their application in the healthcare industry - Contributions by global leaders and experts from academia, industry and regulatory agencies, who have been considered as pioneers in the application of herbal biomolecules in the diverse healthcare fields - Includes updated literature review along with practical examples and research case studies

Download or read book Discovery and Development of Neuroprotective Agents from Natural Products written by Goutam Brahmachari and published by Elsevier. This book was released on 2017-05-18 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discovery and Development of Neuroprotective Agents from Natural Products draws together global research on medicinal agents from natural sources as starting points for the design of neuroprotective drugs. From the prediction of promising leads and identification of active agents to the extraction of complex molecules, the book explores a range of important topics to support the development of safer, more economical therapeutics for these increasingly prevalent diseases. Beginning with an overview of current developments in the field, the book goes on to explore the identification, extraction and phytochemistry of such neuroprotective agents as antioxidants, biophenols and naturally occurring anti-inflammatory steroid analogues. Specific natural sources of bioactive agents are reviewed, and the development of these agents into therapeutics for a number of specific neurological disorders, including Alzheimer's disease, Parkinson's disease and ischemic brain stroke, are discussed. Combining the expertise of specialists from around the world, this in the Natural Products Drug Discovery series aims to support and encourage researchers in the investigation of natural sources as starting points for the development of standardized, safe and effective neuroprotective drugs. - Features chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery - Includes comprehensive coverage of cutting-edge research advances in the design of drugs from natural products targeted at different kinds of neurodegenerative diseases - Offers a practical review of identification, isolation and extraction techniques to support medicinal chemists in the lab

Download or read book Plant Secondary Metabolism written by David S. Seigler and published by Springer Science & Business Media. This book was released on 1998-12-31 with total page 774 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant Secondary Metabolism presents a basic understanding of the origin of the compounds, the nature of the precursors involved, and the basic reactions, mechanisms, and stereochemistry. The origin of groups of secondary metabolites is linked to evolutionary principles, and their biological activity is viewed in a context of chemical ecology. Topics are treated comprehensively, enabling the reader to understand not only a particular group of compounds, but also how each group fits into the whole. In addition, the text allows readers to systematically survey various secondary metabolites and gain a quick working knowledge, which can be applied to problems in a particular field. Those researchers and students who will be most intrigued by this publication's broad overview on plant secondary metabolites come from a diverse range of disciplines, including agronomy, anthropology, biochemistry, biology, botany, chemistry, ecology, entomology, food science, forestry, geology, horticulture, pharmacognosy, plant biology, plant sciences, toxicology, and zoology.

Download or read book Encyclopedia of Chromatography Print written by Jack Cazes and published by CRC Press. This book was released on 2001-06-29 with total page 970 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical, single-volume source collects up-to-date information on chromatographic techniques and methodologies for the solution of analytical and preparative problems applicable across a broad spectrum of disciplines including biotechnology, pharmaceuticals, environmental sciences, polymers, food additives and nutrients, pathology, toxicology, fossil fuels, and nuclear chemistry. It highlights real-world applications, easy-to-read fundamentals of problem solving and material identification methods, and detailed references. Written by over 180 esteemed international authorities and containing over 300 chapters, 2600 works cited, and 1000 drawings, equations, tables, and photographs, the Encyclopedia of Chromatography covers high-performance liquid, thin-layer, gas, affinity, countercurrent, supercritical fluid, gel permeation, and size exclusion chromatographies as well as capillary electrophoresis, field-flow fractionation, hyphenated techniques, and more. PRINT/ONLINE PRICING OPTIONS AVAILABLE UPON REQUEST AT [email protected]

Download or read book Bacterial Metabolism written by H. W. Doelle and published by Academic Press. This book was released on 2014-06-28 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial Metabolism focuses on metabolic events that occur in microorganisms, as well as photosynthesis, oxidation, polysaccharide formation, and homofermentation. The book first discusses the thermodynamics of biological reactions, photosynthesis and photometabolism, and chemosynthesis. Free energy, photosynthesis, enzymes, and terminology in bacterial metabolism are elaborated. The manuscript then examines acetic acid bacteria and lactic acid bacteria. Discussions focus on lactate, ethanol, glucose, and glycerol metabolism, glycol oxidation, homofermentation, polysaccharide formation, and electron transport systems. The publication takes a look at pseudomonadaceae and nitrogen metabolism as an energy source for anaerobic microorganisms. Topics include metabolism of pairs of amino acids, single amino acid metabolism, oxidation of glycolate and malonate, and oxygenases. The book is a dependable source of information for readers interested in bacterial metabolism.

Download or read book Phytochemicals in Human Health written by Venketeshwer Rao and published by BoD – Books on Demand. This book was released on 2020-02-12 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Naturally present bioactive compounds in plants are referred to as "Phytochemicals" and are being studied extensively for their role in human health. Studies have shown that they can have an important role to play in the prevention and management of several human diseases. Recognizing the increasing interest in this area, this book is being published in response to the need for more current information globally about phytochemicals and their role in human health. Chapters of the book are authored by internationally recognized authors who are experts in their respective field of expertise. The chapters represent both original research as well as up-to-date and comprehensive reviews. We are sure that the book will be an important reference source meeting the needs of a wide range of interest groups.

Download or read book Plant Growth written by Everlon Rigobelo and published by BoD – Books on Demand. This book was released on 2016-11-16 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last few decades, the prevalence of studies about plant growth has dramatically grown in most regions of the world. Many aspects have been investigated related to this phenomenon. If we can gain understanding of how plants grow, then we may be able to manipulate it to reduce both chemical fertilizer use and its environmental impact without decreasing the yield. This book provides information about the use of bio-agents, plant health, plant pathogen, property of melanin, and the influence of rootstock and root growth. We hope this information will be useful for all the people who work with this hot topic.