Download or read book Coronary Artery Disease and the Myocardial Ischemic Cascade An Issue of Radiologic Clinics of North America written by U. Joseph Schoepf and published by Elsevier Health Sciences. This book was released on 2015-04-07 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: State of the Art CT and MR Imaging of Coronary Artery Disease and the Myocardial Ischemic Cascade is covered extensively in this issue of Radiologic Clinics. Articles will include: Imaging Coronary Artery Disease and the Myocardial Ischemic Cascade; CT Imaging of Coronary Artery Plaque; Coronary CT Angiography in Clinical Practice; Beyond Stenosis Detection: CT Approaches for Determining the Functional Relevance of Coronary Artery Disease; CT Assessment of Coronary Artery Disease; Cardiac CT for the Evaluation of the Acute Chest Pain Syndrome; Current State of the Art Cardiovascular MRI Techniques for Assessment of Ischemic Heart Disease; Global and Regional Functional Assessment of Ischemic Heart Disease with Cardiac MRI; MRI of the Coronary Vasculature: Imaging the Lumen, Wall and Beyond; Delayed Enhanced Viability Imaging: Techniques and Clinical Applications; Tissue Characterization of the Left Ventricular Myocardium: State of the Art Techniques and Emerging Clinical Utility; Stress Cardiac MRI: the Role of Stress Functional Assessment and Perfusion Imaging in the Evaluation of Ischemic Heart Disease, and much more!

Download or read book Coronary Artery Disease and the Myocardial Ischemic Cascade written by U. Joseph Schoepf and published by . This book was released on 2015 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Silent Myocardial Ischemia written by W. Rutishauser and published by . This book was released on 1984-05-01 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Diseases of the Chest Breast Heart and Vessels 2019 2022 written by Juerg Hodler and published by Springer. This book was released on 2019-02-19 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As such, it presents a comprehensive review of current knowledge on imaging of the heart and chest, as well as thoracic interventions and a selection of "hot topics". The book is intended for radiologists, however, it is also of interest to clinicians in oncology, cardiology, and pulmonology.

Download or read book New Paradigms of Coronary Artery Disease written by G. Heusch and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Detailed analyses of regional myocardial blood flow, function, metabolism and morphology in ischemic and reperfused myocardium have led to the identifi cation of important phenomena, i. e. , myocardial hibernation, myocardial stun ning and ischemic preconditioning. Both the hibernating and the stunned myocardium characterize viable though dysfunctional as distinguished from necrotic tissue. With the advent of reperfusion procedures, the distinction between reversibly injured, hypofunctional myocardium from irreversibly injured, hypofunctional myocardium is of utmost clinical importance. The pathophysiological distinction of hibernating and stunned myocardium is con troversial, but reperfusion is mandatory anyway. Ischemic preconditioning is the most powerful maneuver known so far to delay infarct development. Its clinical significance has been suggested from retrospective analyses of data from patients suffering a myocardial infarction as well as from controlled PTCA studies. Whether or not preconditioning can be achieved pharmacologically in the clinical setting remains to be established. The mechanisms and signal cascade underlying myocardial hibernation, myocardial stunning and ischemic preconditioning are not clear in detail. Over the last year, focussed issues on myocardial hibernation, myocardial stunning and ischemic preconditioning were published in Basic Research in Car diology; they have received great interest and a good response. Therefore, these focussed issues are now combined and published as a separate monograph. We express our gratitude once more to all our colleagues who contributed to this monograph, to Ms. Ibkendanz of Steinkopff, and to Ms. Philipp and Mr. Heinrichs from Bayer AG Germany, who supported this additional publication.

Download or read book Stress Echocardiography written by Eugenio Picano and published by Springer Nature. This book was released on 2023-10-19 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the seventh edition of a long-selling book (first edition 1991) that was translated into Italian, French, Chinese, Portuguese, Spanish, English. In the last ten years, stress echocardiography has exploded in its breadth and variety of applications. From a one-fits-all approach (wall motion by 2D-echo in the patient with known or suspected coronary artery disease), the field has progressed to an omnivorous, next-generation laboratory employing a variety of technologies (from M-Mode to 2D, from pulsed, continuous, color and tissue Doppler to lung ultrasound) on patients covering the entire spectrum of severity (from elite athletes to patients with end-stage heart failure) and ages (from children with congenital heart disease to the elderly with aortic stenosis). This new edition is enriched with over 300 figures, 150 tables and video-clips. In a societal and economic climate of increasing pressure for appropriate, justified and optimized imaging, stress echocardiography offers the great advantages of being radiation-free, relatively low cost, with minimal environmental impact, and with a staggering versatility: we can get more (information) with less (cost and risk). The volume will be a tremendous aid to current best practices for all health operators who intend to use stress echocardiography and ultrasound for diagnosis and guidance of optimal management in their patients.

Download or read book Clinical Guide to Cardiology written by Christian Fielder Camm and published by John Wiley & Sons. This book was released on 2016-03-07 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Guide to Cardiology is a quick-reference resource, packed full of bullet points, diagrams, tables and algorithms for the key concepts and facts for important presentations and conditions within cardiology. It provides practical, evidence-based information on interventions, investigations, and the management of clinical cardiology. Key features include: A clear evidence-base providing key guidelines and clinical trials in each chapter Coverage of examination techniques, common conditions, imaging modalities (including ECGs, chest X-rays, MRI and CT), interventional therapies, and pharmacology A companion website at www.wiley.com/go/camm/cardiology featuring audio clips, developed for differing levels of knowledge, that explain key concepts or an area in greater detail, as well as numerous additional clinical case studies, audio scripts, and self-assessment material

Download or read book Ischemic Heart Disease written by Erling Falk and published by CRC Press. This book was released on 2007-03-28 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This straightforward guide to the recognition and management of ischemic heart disease provides clinically relevant information needed by today's medical practitioners. The book covers the disease's epidemiology, pathogenesis, clinical presentation, diagnostic tests, differential diagnosis, treatment, and prognosis. Topics include detection of myoc

Download or read book Comprehensive Insights into Acute Coronary Syndrome Pathways Interventions and Holistic Recovery written by Dr. Spineanu Eugenia and published by Dr. Spineanu Eugenia. This book was released on 2024-07-01 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Comprehensive Insights into Acute Coronary Syndrome: Pathways, Interventions, and Holistic Recovery" delves deep into the multifaceted landscape of Acute Coronary Syndrome (ACS), offering a meticulous exploration of its intricate pathways, comprehensive interventions, and the crucial journey towards holistic recovery. This treatise serves as an exhaustive guide, meticulously crafted by medical experts and biochemistry scholars, unraveling the complexities of ACS with precision and depth. The treatise meticulously dissects the pathophysiology behind ACS, unraveling the intricate mechanisms of atherosclerosis, plaque rupture, thrombosis formation, and the ensuing ischemic cascade. It illuminates the epidemiology, risk factors, and underlying genetic predispositions while exploring the interconnected role of lifestyle factors, comorbidities, and the structural intricacies of the heart and coronary arteries.

Download or read book Pathophysiology and Rational Pharmacotherapy of Myocardial Ischemia written by G. Heusch and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ischemie heart disease is still the most frequent cause of death in the western world. There have been significant achievements in diagnostic procedures as well as in the medical, invasive, and surgiealtreatment ofischemieheart disease inrecent years. A variety ofdrugs are availablefor the pharmacotherapyofischemieheart disease, par ticularly nitrates, ß-blockers, and calcium-antagonists which are used as mono therapy or in various combinations. However, the selection of patients for a certain treatment, as weIl as the optimization of an individual treatment are still largely empirical. On the other hand, the recent advances in experimental cardiology emphasize the extremely complex and dynamie scenario of ischemic heart disease, involving endothelial damage, coagulation processes, metabolie and morphologie derangements, coronary constrictor mechanisms, blood flow redistribution, arrhythmogenesis, contraetile dysfunction during ischemia and reperfusion, and finally lack or presence of pain perception. Therefore, it appears desirable to close the gap between experimental and clinical cardiology and, thus, to provide a pathophysiologieal basis for rational cliniealdecisions with respect to diagnostic and therapeutic procedures. The idea for this book arose during the preparation of a seminar series on experi mental cardiology, when I found it diffieultto collect the pertinentinformation from textbooks of cardiology, physiology, pathology, and pharmacology, as well as from numerous review and original artieies on specifictopies. I am now very grateful that expert cliniealand experimental colleagues from around the world have joined me in the effort to provide a comprehensive textbook on the pathophysiology of myocar dial ischemia and its rational pharmacotherapy.

Download or read book Stress Echocardiography written by Eugenio Picano and published by Springer. This book was released on 2015-10-06 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: This sixth edition is enriched by over 300 figures, 150 tables and a video-companion collecting more than 100 cases also presented in the format of short movies and teaching cartoons. This extensively revised and enlarged edition of this long-seller documents the very significant advances made since the fifth (2009) edition and is entirely written by Eugenio Picano, a pioneer in the field sharing his lifetime experience with the help of an international panel of 50 contributors from 22 countries representing some of the best available knowledge and expertise in their respective field. In a societal and economic climate of increasing pressure for appropriate, justified and optimized imaging, stress echocardiography offers the great advantages of being radiation-free, relatively low cost, and with a staggering versatility: we can get more (information) with less (cost and risk). For a long time, the scope and application of stress echo remained focused on coronary artery disease. In the last ten years, it has exploded in its breadth and variety of applications. From a black-and-white, one-fits-all approach (wall motion by 2D-echo in the patient with known or suspected coronary artery disease) now we have moved on to a omnivorous, next-generation laboratory employing a variety of technologies (from M-Mode to 2D and pulsed, continuous, color and tissue Doppler, to lung ultrasound and real time 3D echo, 2D speckle tracking and myocardial contrast echo) on patients covering the entire spectrum of severity (from elite athletes to patients with end-stage heart failure) and ages (from children with congenital heart disease to the elderly with low-flow, low-gradient aortic stenosis).

Download or read book Magnetic Resonance Imaging of Myocardial Deformation and Scarring in Coronary Artery Disease written by Johan Kihlberg and published by Linköping University Electronic Press. This book was released on 2017-11-15 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although improved treatments have reduced the rates of acute complications from myocardial infarction, sequelae such as heart failure and sudden death threaten the future wellbeing of those patients. Secondary prevention after myocardial infarction is related to cardiovascular risk factors and the effect of the infarct on left ventricular function. Cardiovascular magnetic resonance imaging (CMR) is necessary to determine the size of the infarct scar and can with great precision determine left ventricular volumes, left ventricular ejection fraction, and deformation (strain and torsion). The purpose of this thesis was to improve on CMR methods to facilitate image acquisition and post processing in patients with high risk of coronary artery disease (CAD). In Paper 1, a three-dimensional phase-sensitive inversion-recovery (3D PSIR) sequence was modified to measure T1 during a single breath hold. The measured T1 values were used to extrapolate a map of T1 relaxation, which avoided the time-consuming manual determination of the inversion time. The data collection consisted of phantom experiments, Monte Carlo simulations of the effect of various heart rates, and clinical investigation of 18 patients with myocardial infarction. Scar images created with the modified sequence were compared to those created with the standard sequence. The 3D PSIR sequence was able to measure T1 relaxation with a high accuracy up to 800 ms, which is in the suitable range for scar imaging. Simulated arrhythmias showed that the method was robust and able to tolerate some variation in heart rate. The modified sequence provides measurements of inversion time that can be used to facilitate standard scar imaging or to reconstruct synthetic scar images. Images of infarct scar obtained with the 3D PSIR sequence bore striking similarity to images obtained with the standard sequence. In Paper 2, 125 patients with high risk of CAD were investigated using the displacement encoding with stimulated echoes (DENSE) sequence. Image segments with infarct scar area >50% (transmurality) could be identified with a sensitivity of 95% and a specificity of 80% based on circumferential strain calculated from the DENSE measurements. The DENSE sequence was also applied in other directions, but its sensitivity and specificity to detect scar was lower than when used for circumferential strain. In Paper 3, 90 patients with high risk of CAD were examined by DENSE, tagging with harmonic phase (HARP) imaging and cine imaging with feature tracking (FT), to detect cardiac abnormalities as manifested in end-systolic circumferential strain. Circumferential strain calculated with DENSE had higher sensitivity and specificity than the competing methods to detect infarction with transmurality >50%. Global circumferential strain measured by DENSE correlated better with global parameters such as left ventricular ejection fraction, myocardial wall mass, left ventricular end-diastolic and end-systolic volume; than strain measured by FT or HARP. In Paper 4, myocardial torsion was investigated using DENSE, HARP, and FT in 48 patients with high risk of CAD. Torsion measured by each of the three methods was correlated with other global measures such as left ventricular ejection fraction, left ventricular mass, and left ventricular end-diastolic and end-systolic volumes. The torsion measurements obtained with DENSE had a stronger relationship with left ventricular ejection fraction, left ventricular mass, and volumes than those obtained with HARP or FT. DENSE was superior to the other methods for strain and torsion measurement and can be used to describe myocardial deformation quantitatively and objectively.

Download or read book Coronary Microvascular Dysfunction written by Filippo Crea and published by Springer Science & Business Media. This book was released on 2013-08-15 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, thus becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection and management of CMD in their everyday activity.

Download or read book Bioresorbable Scaffolds written by Yoshinobu Onuma and published by CRC Press. This book was released on 2017-10-02 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the coronary bioresorbable scaffold, a new interventional treatment for coronary artery disease, differentiated from a permanent metallic stent. The book provides an overview of the technology including non-clinical studies and clinical evidences in order to help clinicians understand the appropriate application of the technology and the optimal techniques of implantation. It covers the basics of bioresorbable scaffolds; bench test results; preclinical studies; clinical evidences; and tips and tricks of implantation.

Download or read book Echocardiography in Acute Coronary Syndrome written by Eyal Herzog and published by Springer Science & Business Media. This book was released on 2009-12-19 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronary artery disease is the most commonly encountered problem in adult cardiology in the world. Echocardiography is the most commonly used imaging modality encountered in cardiology practice in the world. Even though there are many Acute Coronary Syndrome (ACS) reference books and echocardiography reference books, there is no single practical book so far in the literature with focus on the combined topics. The authors believe that this will be the first book to provide information on how echocardiography can be used in, prevention, diagnosis and treatment of ACS.

Download or read book Silent Myocardial Ischemia written by J. Morganroth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although some investigators have questioned the importance and even the existence of silent myocardial ischemia, documentation presented at this two day symposium leaves little doubt about its existence and importance. It has been estimated that about 3 million of the estimated 4 million angina sufferers in the United states have frequent episodes of silent myocardial ischemia. Although it is not possible to define how many Americans die due to silent ischemia, it has been suggested that the mortality rate may exceed hundreds of thousands of victims annually. Unfortunately, there still remains a lack of definitive information as to why some ischemic events are painless. Some suggest the concept that the location and size of the myocardium at jeopardy relates to pain, that the pain threshold varies from patient to patient or that there are neurological deficits in the myocardium of some patients with silent ischemia. Abnormalities in myocardial perfusion and function can occur without pain. An interesting observation presented by several investigators has been that when a coronary artery is occluded in man, no ischemic pain is perceived for the first 30 seconds. Only after a 30 second period or so of occlusion does angina occur. An even more confusing observation is that some 30 second periods of occlusion of the same vessel in the same patient results in angina while the next occlusion can be a totally silent event.

Download or read book Myocardial Ischemia and Preconditioning written by Naranjan S. Dhalla and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current evidence suggests that the ischemic preconditioning response is a multi-factorial process consisting of an initial early trigger, an intermediate mediator, and an end effector. Each of these steps in is now its own intense area of investigation. The need to render the heart ischemic for a brief period to invoke the preconditioning response is currently the major factor limiting clinical application of this powerful cardioprotective strategy. Recent research efforts have utilized brief exposures to pharmacological agents, in lieu of a brief preconditioning ischemia, to trigger/mimic the ischemic preconditioning-induced response. The World Heart Congress held in Winnipeg in July 2001 provided a forum for the presentation of new insights into the basic mechanisms of ischemia and reperfusion injury, as well as novel strategies to protect the heart from cell death, ventricular arrhythmias, and contractile dysfunction. Many pioneers in the fields of ischemia-reperfusion injury and preconditioning-induced protection presented there and the chapters in this book represent selected papers from these symposia.