Download or read book Copper Containing Molecules written by Joan S. Valentine and published by Academic Press. This book was released on 2002-11-01 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: A wide range of researchers are currently investigating different properties and applications for copper-containing proteins. Biochemists researching metal metabolism in organisms ranging from bacteria to plants to animals are working in a completely different area of discovery than scientists studying the transportation and regulation of minerals and small molecule nutrients. They are both working with copper-containing proteins, but in very different ways and with differing anticipated outcomes.
Download or read book Copper in Drinking Water written by National Research Council and published by National Academies Press. This book was released on 2000-04-12 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: The safety of the nation's drinking water must be maintained to ensure the health of the public. The U.S. Environmental Protection Agency (EPA) is responsible for regulating the levels of substances in the drinking water supply. Copper can leach into drinking water from the pipes in the distribution system, and the allowable levels are regulated by the EPA. The regulation of copper, however, is complicated by the fact that it is both necessary to the normal functioning of the body and toxic to the body at too high a level. The National Research Council was requested to form a committee to review the scientific validity of the EPA's maximum contaminant level goal for copper in drinking water. Copper in Drinking Water outlines the findings of the committee's review. The book provides a review of the toxicity of copper as well as a discussion of the essential nature of this metal. The risks posed by both short-term and long-term exposure to copper are characterized, and the implications for public health are discussed. This book is a valuable reference for individuals involved in the regulation of water supplies and individuals interested in issues surrounding this metal.
Download or read book Biochemical Aspects of Copper written by Charles Archibald Owen and published by William Andrew. This book was released on 1982 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: An authoritative reference text reviews the current body of knowledge concerning the isolation, characterization, and biochemical function of in vivo copper-containing species as related to copper metabolism and in vivo copper complexes for clinical biochemists and nutrition researchers. The material is organized among 3 principal categories: copper proteins and other copper-containing compounds (identified copper proteins (including enzymes) ill- defined copper proteins, possible copper enzymes, and copper porphyrins and other complexes), with references given for each of the 35 proteins and other compounds covered; the chemistry, isolation, function, assay, metabolism, and therapeutic use of ceruloplasmin, including deficiency and excess disorders; and the related topics of copper-protein binding and copper transport. (wz).
Download or read book Copper Oxygen Chemistry written by Kenneth D. Karlin and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers the vastly expanding subject of oxidative processes mediated by copper ions within biological systems Copper-mediated biological oxidations offer a broad range of fundamentally important and potentially practical chemical processes that cross many chemical and pharmaceutical disciplines. This newest volume in the Wiley Series on Reactive Intermediates in Chemistry and Biology is divided into three logical areas within the topic of copper/oxygen chemistry— biological systems, theory, and bioinorganic models and applications—to explore the biosphere for its highly evolved and thus efficient oxidative transformations in the discovery of new types of interactions between molecular oxygen and copper ion. Featuring a diverse collection of subject matter unified in one complete and comprehensive resource, Copper-Oxygen Chemistry probes the fundamental aspects of copper coordination chemistry, synthetic organic chemistry, and biological chemistry to reveal both the biological and chemical aspects driving the current exciting research efforts behind copper-oxygen chemistry. In addition, Copper-Oxygen Chemistry: Addresses the significantly increasing literature on oxygen-atom insertion and carbon-carbon bond-forming reactions as well as enantioselective oxidation chemistries Progresses from biological systems to spectroscopy and theory, and onward to bioinorganic models and applications Covers a wide array of reaction types such as insertion and dehydrogenation reactions that utilize the cheap, abundant, and energy-containing O2 molecule With thorough coverage by prominent authors and researchers shaping innovations in this growing field, this valuable reference is essential reading for bioinorganic chemists, as well as organic, synthetic, and pharmaceutical chemists in academia and industry.
Download or read book Trace Elements and Minerals in Health and Longevity written by Marco Malavolta and published by Springer. This book was released on 2018-11-13 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the role of trace elements in health and longevity, pursuing a biogerontological approach. It offers essential information on the impact of trace elements on molecular and physiological processes of aging, and on their impact on health in connection with aging. The major topics covered in its 11 chapters, each dedicated to a specific trace element or mineral, are: a) Role of the element in species longevity, b) Recommended intake for longevity in animal species and in the elderly, c) Deficiency and age-related disease, d) Excess/toxicity and age-related disease, and e) Interactions with drugs prescribed in the elderly. Clinical, animal and other laboratory models of interest in aging are included, which enable a more in-depth analysis to be made. The respective chapters are a mixture of overviews and more in-depth reviews in which the mechanisms of aging are described from the point of view of their specific interactions with trace elements and minerals.
Download or read book Handbook of Copper Compounds and Applications written by H. Wayne Richardson and published by CRC Press. This book was released on 1997-01-16 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing the utility of copper-related compounds, this text illustrates the numerous current and potential uses from agricultural bactericides and wood preservatives to colourants and solar cells. It discusses the properties and behaviour of the copper ion, copper compounds' employment in organic polymerization and isomerization reactions, the enhancement of feed efficiencies and additives in plant and animal nutrition, and more.
Download or read book Molecular and Structural Studies on Copper Containing Oxidases written by Christian Richard Paul Kurtis and published by . This book was released on 2001 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Copper Bioinorganic Chemistry From Health To Bioinspired Catalysis written by Jalila Simaan and published by World Scientific. This book was released on 2023-07-26 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinorganic chemistry is an interdisciplinary research field which centers on metals in biology. Over the past few decades, advances in chemistry, biology as well as in spectroscopic methods have shed light on the role of copper in human pathologies and allowed the growing discovery of copper-containing biological systems. Following this trend, much effort is being constantly chanelled towards understanding these fundamental biological processes or enzymes. In addition, chemists are developing molecules to target copper or copper enzymes as therapeutic tools. On the other hand, inspired by the function of biological systems, small molecular weight complexes inspired by the active site of copper enzymes are being prepared and studied. These bioinspired complexes can function both as mechanistic tools and as functional catalysts for oxidative transformations.The seven chapters in this book, contributed by internationally recognized authors cover recent developments on these aspects illustrated by interdisciplinary fields from biology, chemistry, spectroscopy to bioinspired catalysis. It contains aspects ranging from human health issues (copper homeostasis in bacteria and the development of molecules as anticancer or antibacterial agents) to bioinspired catalysis.
Download or read book The Chemistry of Copper Silver and Gold written by A. G. Massey and published by Elsevier. This book was released on 2017-01-31 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Chemistry of Copper, Silver and Gold deals with the chemistry of copper, silver, and gold and covers topics ranging from the occurrence and metallurgy of copper to copper compounds and compounds containing copper-metal bonds, compounds of silver, and gold alloys. Hydrides and halides, cyanides and oxides, hydroxides and oxyacids, and thiocyanates and selenocyanates are also discussed. This volume is comprised of three chapters and opens with a brief history of copper, along with its occurrence and metallurgy, analysis, and compounds. The next chapter is devoted to silver and its compounds, while the last chapter describes gold, its isotopes and alloys, chemistry, and gold hydrides and halides, cyanides and oxides, hydroxides and oxyacids. Gold sulfides, selenides and tellurides, and nitrates are also considered, along with nitrides, azides, phosphides, and arsenides; and thiosulfates, selenates, selenites, thiocyanates, and selenocyanates. The final sections look at gold complexes and the organometallic and analytical chemistry of gold. This book will be a valuable source of information for inorganic chemists.
Download or read book Metal Containing Enzymes written by and published by Academic Press. This book was released on 2014-11-24 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series is the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics. Describes advances in metal-containing enzymes Chapters are written by authorities in their field Targeted to a wide audience of researchers, specialists, and students The information provided in the volume is well supported by a number of high quality illustrations, figures, and tables
Download or read book Spectroscopy of Biological Molecules Modern Trends written by P. Carmona and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 1997 European Conference on Spectroscopy of Biological Molecules (ECSBM) is the seventh in a biennial series of conferences devoted to the applications of molecular spectroscopy to biological molecules and related systems. The interest of these conferences rests mainly on the relationship between the structure and physiological activity of biological molecules and related systems of which these molecular species form part. This volume ofECSBM contains articles prepared by the invited lecturers and those making poster presentations at the seventh ECSBM. The reader will find mainly applications of vibrational spectroscopy to protein structure and dynamics, biomembranes, molecular recognition, nucleic acids and other biomolecules and biological systems containing specific chromophors. Biomedical applications of vibrational spectroscopy are expanding rapidly. On the other hand, a significant number of the papers describe applications of other methods, such as NMR, circular dichroism, optical absorption and fluorescence, X-ray absorption and diffraction and other theoretical methods. One aim has been to achieve a well balanced, critically comparative review of recent progress in the field of biomolecular structure, bonding and dynamics based on applications of the above spectroscopic methods. A great part of the contributions included in this volume are devoted to biomedical and biotechnological applications and provide a broadly based account of recent applicationS in this field. The content of this book has been organized in sections corresponding mainly to the different types of biological molecules investigated. This book includes also another section related to theoretical methods where MO calculations of vibrational frequencies dominate clearly the topic.
Download or read book The Prion Protein written by Jorg Tatzelt and published by . This book was released on 2010 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: A conformational transition of the cellular prion protein (PrPC) into an aberrantly folded isoform designated scrapie prion protein (PrPSc) is the hallmark of a variety of neurodegenerative disorders collectively called prion diseases. They include Creutzfeldt-Jakob disease and Gerstmann-Stäussler-Scheinker syndrome in humans, scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle and chronic wasting disease (CWD) in free-ranging deer. In contrast to the deadly properties of misfolded PrP, PrPC seems to possess a neuroprotective activity. More-over, animal models indicated that the stress-protective activity of PrPC and the neurotoxic effects of PrPSc are somehow interconnected. In this timely book, leading scientists in the field have come together to highlight the apparently incongruous activities of different PrP conformers. The articles outline current research on celluar pathways implicated in the formation and signaling of neurotoxic and physiological PrP isoforms and delineate future research direction. Topics covered include the physiologcial activity of PrPC and its possible role as a neurotrophic factor, the finding that aberrant PrP conformers can cause neurodegeneration in the absence of infectious prion propagation, the requirement of the GPI anchor of PrPC for the neurotoxic effects of scrapie prions, the pathways implicated in the formation and neurotoxic properties of cytosolically localized PrP, the impact of metal ions on the processing of PrP, and the role of autophagy in the propagation and clearance of PrPSc. The book is fully illustrated and chapters include comprehensive reference sections. Essential reading for scientists involved in prion research.
Download or read book Biochemistry of Copper written by Maria C. Linder and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Copper has long been known as essential to living systems, in part through its fundamental role in electron transport and respiration. Over the years into the present, its involvement in an ever increasing number of processes in all kinds of organisms has become apparent, and new and exciting vistas of its roles in such areas as the central nervous system, and in humoral functions, are appearing on the horizon. Although the biochemistry of this element has not been studied nearly as much as that of many others, a for midable amount of work has been carried out. It has thus been a challenge to produce a summary of what has been found that provides both breadth and depth. My goal has been to try to be as comprehensive as possible, within some limitations. I have tried to provide basic information and basic data that should continue to be useful for a long time. The goal has also been to interpret where we currently stand in our knowledge of the structure, function, regulation, and metabolism of Cu-dependent processes and sub stances, especially proteins. Thus, I have tried to make this a source book for historic as well as current information on all aspects of copper bio chemistry, and a summary of our current knowledge of copper-dependent proteins and processes. Most of the research on copper has been carried out on vertebrates, especially mammals. This has played a role in the organization of the book.
Download or read book Clinical and Translational Perspectives on Wilson Disease written by Nanda Kerkar and published by Academic Press. This book was released on 2018-10-15 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Wilson Disease: A Worldwide Perspective and Translational Approach brings together the genetics & cell and structural biology of Wilson Disease into one contemporary, easy to navigate handbook. Aimed to meet the needs of the diverse clinical and research communities of Wilson Disease, this reference provides a worldwide approach that is concise and translational. Specifically, it provides a basis for clinicians to appreciate 'basic science' aspects of Wilson disease and similarly a basis for researchers to understand the clinical disorder on which their research is focused, fostering constructive dialogue and progress for this puzzling disorder. Offers a contemporary worldwide perspective with contributions from international experts in the field Delivers numerous succinct expert chapters with summaries designed for quick reference Includes a "How-to" appendix for diagnosis and management tips Contains access to a companion website with a self-help teaching module, links to key resources, and an extended reference list
Download or read book Tietz Fundamentals of Clinical Chemistry Passcode Only written by Carl A. Burtis and published by W B Saunders Company. This book was released on 2007-11-06 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a Pageburst digital textbook; the product description may vary from the print textbook. A condensed, student-friendly version of Tietz Textbook of Clinical Chemistry, this text uses a laboratory perspective to provide you with the chemistry fundamentals you need to work in a real-world, clinical lab. Accurate chemical structures are included to explain the key chemical features of relevant molecules. Offering complete, accurate coverage of key topics in the field, it's everything that you expect from the Tietz name! More than 500 illustrations and easy-to-read tables help you understand and remember key concepts. Key words, learning objectives, and other student-friendly features reinforce important material. Chapter review questions are included in an appendix to test your knowledge. A two-color design makes it easier to read and easy to find important topics. In-depth, reader-friendly content is appropriate for MT/CLS and MLT/CLT students and may also be used by laboratory practitioners, pathology residents, and others. A new chapter on newborn screening discusses the basic principles, screening recommendations, inborn errors, methods, and interpretation of results. A comprehensive glossary provides easy-to-find definitions of key terms. An Evolve website provides regular updates of content, answers to review questions, and web links to related sites for further research and study.
Download or read book Diet and Health written by National Research Council and published by National Academies Press. This book was released on 1989-01-01 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.
Download or read book Enzyme Engineering and Evolution General Methods written by and published by Academic Press. This book was released on 2020-09-05 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series
