Download or read book Cooley s Anemia written by Elliott P. Vichinsky and published by Wiley-Blackwell. This book was released on 2005-11-29 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cooley's anemia, or thalassemia major, is a blood disorder characterized by a marked increase in F hemoglobin and a decrease in the production of certain oxygen-carrying proteins in red blood cells. Thalassemia major is the most severe form of the chronic familial anemias that result from the premature destruction of red blood cells and is inherited as an autosomal recessive trait. In the years since the Seventh Cooley's Anemia Symposium, held in 1997, major advances have taken place in the understanding and treatment of the disease. The molecular mechanisms responsible for the switch from fetal hemoglobin to adult hemoglobin production have been further clarified, while new drugs to enhance the production of fetal hemoglobin and relieve the anemia of thalassemia have been introduced and studied. Understanding of the relationship between molecular genotype and clinical phenotype has been advanced, and the techniques for molecular diagnosis, including prenatal diagnosis, have been vastly improved. Most importantly, there have been dramatic improvements in the treatment and prevention of complications of thalassemia. As a result, patients are now living longer, albeit with more disability. Problems such as osteoporosis, heart failure, growth hormone deficiency, pulmonary hypertension, and infertility can now be detected early and treated. This volume not only focuses on the advances over the last six or seven years, but also illuminates many unsolved but critically important issues in the understanding and treatment of thalassemia, thus offering the scientific, clinical, care-giving, and patient communities the most up-to-date exchange on the current and future perspectives of the disease. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Download or read book Cooley s Anemia written by Elliott P. Vichinsky and published by . This book was released on 2005 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cooley's anemia, or thalassemia major, is a blood disorder characterized by a marked increase in F hemoglobin and a decrease in the production of certain oxygen-carrying proteins in red blood cells. Thalassemia major is the most severe form of the chronic familial anemias that result from the premature destruction of red blood cells and is inherited as an autosomal recessive trait. In the years since the Seventh Cooley's Anemia Symposium, held in 1997, major advances have taken place in the understanding and treatment of the disease. The molecular mechanisms responsible for the switch from fetal hemoglobin to adult hemoglobin production have been further clarified, while new drugs to enhance the production of fetal hemoglobin and relieve the anemia of thalassemia have been introduced and studied. Understanding of the relationship between molecular genotype and clinical phenotype has been advanced ...

Download or read book Turning Blood Red written by Arthur Bank and published by World Scientific. This book was released on 2009 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: disorders, and heart disease. It also provides new insights which may lead to new therapies." --Book Jacket.

Download or read book Cooley s Anemia written by Elliott P. Vichinsky and published by Wiley-Blackwell. This book was released on 2010-08-30 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This volume presents manuscripts stemming from the 'Ninth Cooley's Anemia Symposium,' held October 21-24, 2009 at the New York Academy of Sciences, and sponsored by the Cooley's Anemia Foundation and the New York Academy of Sciences"--Contents p.

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