Download or read book Conversations on Cardiac Physiology written by Mark Noble and published by Cambridge Scholars Publishing. This book was released on 2023-12-08 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses and corrects widespread misconceptions regarding heart physiology. Such misconceptions include: the voltage in cells is attributed to potassium ion concentration differences between the extracellular and intracellular compartments, which are the same in all organs of the body, whereas the voltage in cells of these same organs vary widely. This book argues that depolarisation and repolarisation can be explained by electron outflow and mitochondrial production, respectively; and that the trigger for internal calcium ion release is calcium ions bound to the inner leaflet of the cell membrane. In the book, Starling’s Law is contrasted with contractility increase, and it is posited that hypertension is not caused by salty diet, coronary artery disease risk is not correlated with total cholesterol (rather, only with some specific cholesterols), and that drug administration should be titrated.

Download or read book Cardiovascular Physiology 8 E written by David E. Mohrman and published by McGraw Hill Professional. This book was released on 2014-02-05 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The best cardiovascular physiology text for USMLE and exam review Cardiovascular Physiology is a concise and enjoyable way for you to gain a fundamental knowledge of the basic operating principles of the intact cardiovascular system and how those principles apply to clinical medicine. Succinct but thorough, it focuses on the facts and concepts you must know to get a solid "big picture" overview of how the cardiovascular system operates in normal and abnormal situations. No other text will prove more valuable in enhancing your ability to evaluate the myriad new information you will be exposed to throughout your career, than Cardiovascular Physiology. FEATURES NEW Includes a "Perspectives" section in each chapter that identifies important unresolved issues Clarifies the details of physiologic mechanisms and their role in pathologic states Links cardiovascular physiology to diagnosis and treatment Summarizes key concepts at the end of each chapter Highlights must-know information with chapter objectives Reinforces learning with study questions at the end of each chapter

Download or read book Handbook of Cardiac Anatomy Physiology and Devices written by Paul A. Iaizzo and published by Springer. This book was released on 2015-11-13 with total page 817 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices.

Download or read book Excitation Contraction Coupling and Cardiac Contractile Force written by Donald Bers and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: How is the heartbeat generated? What controls the strength of contraction of heart muscle? What are the links between cardiac structure and function? How does our understanding of skeletal and smooth muscle and non-muscle cells influence our thinking about force development in the heart? Are there important species differences in how contraction is regulated in the heart? How do the new molecular data fit together in understanding the heart beat? What goes wrong in ischemia, hypertrophy, and heart failure? This book paints a modern `portrait' of how the heart works and in this picture the author shows a close-up of the structural, biochemical, and physiological links between excitation and contraction. The author takes the reader through a series of important, interrelated topics with great clarity and continuity and also includes many useful illustrations and tables. The book starts by considering the cellular structures involved in excitation-contraction coupling and then described the characteristics of the myofilaments as the end effector of excitation-contraction coupling. A general scheme of calcium regulation is described and the possible sources and sinks of calcium are discussed in simple, but quantitative terms. The cardiac action potential and its many underlying currents are reviewed. Then the characteristics of some key calcium transport systems (calcium channels, sodium/calcium exchange and SR calcium uptake and release) are discussed in detail. This is then built into a more integrated picture of calcium regulation in succeeding chapters by detailed discussions of excitation-calcium coupling mechanisms (in skeletal, cardiac, and smooth muscle), the interplay between calcium regulatory processes, and finally mechanisms of cardiac inotropy, calcium overload, and dysfunction (e.g., ischemia, hypertrophy, and heart failure). Excitation-Contraction Coupling and Cardiac Contractile Force – Second Edition is an invaluable source of information for anyone who is interested in how the heart beat is controlled and especially suited for students of the cardiovascular system at all levels from medical/graduate students through senior investigators in related fields.

Download or read book Perioperative Hemodynamic Monitoring and Goal Directed Therapy written by Maxime Cannesson and published by Cambridge University Press. This book was released on 2014-09-04 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book provides clinicians and administrators with a comprehensive understanding of perioperative hemodynamic monitoring and goal directed therapy, emphasizing practical guidance for implementation at the bedside. Successful hemodynamic monitoring and goal directed therapy require a wide range of skills. This book will enable readers to: • Detail the rationale for using perioperative hemodynamic monitoring systems and for applying goal directed therapy protocols at the bedside • Understand the physiological concepts underlying perioperative goal directed therapy for hemodynamic management • Evaluate hemodynamic monitoring systems in clinical practice • Learn about new techniques for achieving goal directed therapy • Apply goal directed therapy protocols in the perioperative environment (including emergency departments, operating rooms and intensive care units) • Demonstrate clinical utility of GDT and hemodynamic optimization using case presentations. Illustrated with diagrams and case examples, this is an important resource for anesthesiologists, emergency physicians, intensivists and pneumonologists as well as nurses and administrative officers.

Download or read book Essentials of Cardiac Anesthesia E Book written by Joel A. Kaplan and published by Elsevier Health Sciences. This book was released on 2008-08-15 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by the same stellar editors and contributors responsible for Kaplan's Cardiac Anesthesia, this title presents today's most essential clinical knowledge in cardiac anesthesia in a practical, user-friendly format. A manageable size and affordable price makes this an ideal purchase for every clinician who would like an economical yet dependable resource in cardiac anesthesia. Provides the key cardiac anesthesia information you need to know by authorities you trust. Uses a concise, user-friendly format that helps you locate the answers you need quickly. Features key points boxes in each chapter to help you quickly access the most crucial information. Includes annotated references that guide you to the most practical additional resources. Features a portable size and clinical emphasis that facilitates and enhances bedside patient care. Contains the authoritative guidance of larger reference books without the expense.

Download or read book Essential Concepts of Electrophysiology through Case Studies Intracardiac EGMs written by Roderick Tung, MD, FACC, FHRS and published by Cardiotext Publishing. This book was released on 2015-05-15 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of intracardiac tracings builds on our first book, Essential Concepts of Electrophysiology and Pacing through Case Studies, that guides the reader in developing and refining the key skill of analyzing electrophysiologic recordings. Over 60 cases with a focus on intracardiac EGMs are presented as board exam cases and questions. Tracings are framed by a question, followed by annotated tracings, and a discussion of the correct and potential answers. Cases present a full range of difficulty from simple to advanced. This book will provide a valuable review for a wide variety of professionals — physicians, associated professionals, nurses and technicians — preparing for certification and re-certification examinations in electrophysiology.

Download or read book Current Concepts in Cardiovascular Physiology written by Oscar Garfein and published by Elsevier. This book was released on 2012-12-02 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Concepts in Cardiovascular Physiology examines seven different areas related to the field of cardiac physiology. In addition to the biochemistry and receptor pharmacology of the heart, this book explores coronary physiology, cardiovascular function, and neural and reflex control of the circulation. The electrophysiology and biophysics of cardiac excitation are also considered, along with humoral control of the circulation. This monograph consists of seven chapters and opens with an overview of the biochemistry of the heart, with emphasis on cardiac energy metabolism and the ways in which metabolism and the biochemical pathways are controlled. The mechanisms whereby physiological events influence biochemical activities and vice versa are also discussed. The following chapters look at the chemistry and physiology of myocardial receptors; the complex interplay between the nervous and cardiovascular systems; and the chemical and hormonal factors that regulate, modify, and modulate the cardiovascular system. The influence of humoral, neural, intrinsic, vascular, and myocardial factors on coronary blood flow is also examined, along with muscle mechanics; the biochemical basis of contraction; cardiac function; and the factors determining the heart's electrophysiologic behavior. This text is directed primarily at clinical cardiologists, cardiovascular surgeons, and trainees in their disciplines, as well as internists, medical students, and house officers.

Download or read book Physiology of the Heart written by Arnold M. Katz and published by Lippincott Williams & Wilkins. This book was released on 2010-11-09 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Arnold Katz's internationally acclaimed classic, Physiology of the Heart, is now in its thoroughly revised Fifth Edition, incorporating the latest molecular biology research and extensively exploring the clinical applications of these findings. In the single authored, expert voice that is this book's unique strength, Dr. Katz provides a comprehensive overview of the physiological and biophysical basis of cardiac function, beginning with structure and proceeding to biochemistry, biophysics, and pathophysiology in arrhythmias, ischemia, and heart failure. Emphasis is on the interrelationships of basic processes among the cell, cardiac muscle function, and the biophysics of contractile and electrical behavior. This edition includes new material on cell signaling and molecular biology.

Download or read book Hemodynamic Rounds written by Morton J. Kern and published by John Wiley & Sons. This book was released on 2018-02-09 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The essential resource on cardiac hemodynamics—now in a new edition Hemodynamic Rounds, Fourth Edition is intended to help cardiologists, cardiovascular fellowship trainees, residents and other members of the medical community enhance their understanding of cardiac physiology and its associated hemodynamic presentations in health and disease. This includes the basic principles of flow and pressure measurements, systemic as well as coronary hemodynamics in normal and diseased states, and changes in hemodynamics following interventional procedures ranging from TAVI and valvuloplasty to stent placement. Like its popular predecessors, this new edition draws on case studies to illustrate characteristic cardiac hemodynamic findings and discusses the essential methods used in interpreting pressure waveforms as a diagnostic and monitoring tool. The text is organized into chapters on specific areas of the heart, common cardiac pathophysiologic conditions, and hemodynamic situations resulting from different therapeutic procedures. It includes discussions of both normal and abnormal pressure waveforms. This new edition has been revised throughout to include brand new content on aortic and mitral valve stenosis and regurgitation as well as TAVI and mitral clip hemodynamics. Highlights include: Essential and easy to understand resource for those required to interpret cardiac blood flow and blood pressure tracings Covers hemodynamic assessment by cardiac disorder, plus the bedside applications of hemodynamics Revised throughout and includes brand new content on valve stenosis and regurgitation and TAVI and mitral clip hemodynamics Hemodynamic Rounds: Interpretation of Cardiac Pathophysiology from Pressure Waveform Analysis, Fourth Edition is an indispensable tool for all physicians, nurses, and students responsible for measuring and interpreting cardiac waveforms in cardiac diagnosis and monitoring.

Download or read book Regulation of Cardiac Contractility written by R. John Solaro and published by Biota Publishing. This book was released on 2011-04-01 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contractility describes the relative ability of the heart to eject a stroke volume (SV) at a given prevailing afterload (arterial pressure) and preload (end-diastolic volume; EDV). Various measures of contractility are related to the fraction as the SV/EDV or the ejection fraction, and the dynamics of ejection as determined from maximum pressure rise in the ventricles or arteries or from aortic flow velocities determined by echocardiography. At the cellular level, the ultimate determinant of contractility is the relative tension generation and shortening capability of the molecular motors (myosin cross-bridges) of the sarcomeres as determined by the rates and extent of Ca activation, the turnover kinetics of the cross-bridges, and the relative Ca responsiveness of the sarcomeres. Engagement of the regulatory signaling cascades controlling contractility occurs with occupancy and signal transduction by receptors for neurohumors of the autonomic nervous system as well as growth and stress signaling pathways. Contractility is also determined by the prevailing conditions of pH, temperature, and redox state. Short-term control of contractility is fully expressed during exercise. In long-term responses to stresses on the heart, contractility is modified by cellular remodeling and altered signaling that may compensate for a time but which ultimately may fail, leading to disorders.

Download or read book Practical Pediatric Cardiology written by Alan G. Magee and published by Springer. This book was released on 2015-11-02 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heart disease in children has a number of diagnostic traps for the unwary, and all of us involved in the specialty have been caught at one time or another. For example, it is sometimes very difficult to differentiate between respiratory and cardiac disease in infants and between neurological and cardiac conditions in older children, and the consequences of taking the wrong path can be significant. This book is a collection of cases highlighting situations which can ensnare even the best cardiologist. Although they illustrate the importance of taking a good history and performing a thorough examination, the most important lesson is learning to keep an open mind and develop the ability to think laterally. As clinicians we need to have the confidence to make a decision for our patients but also the humility to be able to acknowledge that we don’t always get it right first time, and it is imperative that we learn from the experience. We hope the reader will find these short chapters interesting and while they are not evidence-based medicine in the true sense, they do represent a wide range of clinical experience from which we can all learn. ​

Download or read book Heart A History written by Sandeep Jauhar and published by Farrar, Straus and Giroux. This book was released on 2018-09-18 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bestselling author of Intern and Doctored tells the story of the thing that makes us tick For centuries, the human heart seemed beyond our understanding: an inscrutable shuddering mass that was somehow the driver of emotion and the seat of the soul. As the cardiologist and bestselling author Sandeep Jauhar shows in Heart: A History, it was only recently that we demolished age-old taboos and devised the transformative procedures that have changed the way we live. Deftly alternating between key historical episodes and his own work, Jauhar tells the colorful and little-known story of the doctors who risked their careers and the patients who risked their lives to know and heal our most vital organ. He introduces us to Daniel Hale Williams, the African American doctor who performed the world’s first open heart surgery in Gilded Age Chicago. We meet C. Walton Lillehei, who connected a patient’s circulatory system to a healthy donor’s, paving the way for the heart-lung machine. And we encounter Wilson Greatbatch, who saved millions by inventing the pacemaker—by accident. Jauhar deftly braids these tales of discovery, hubris, and sorrow with moving accounts of his family’s history of heart ailments and the patients he’s treated over many years. He also confronts the limits of medical technology, arguing that future progress will depend more on how we choose to live than on the devices we invent. Affecting, engaging, and beautifully written, Heart: A History takes the full measure of the only organ that can move itself.

Download or read book An Introduction to Cardiovascular Physiology written by J R Levick and published by Butterworth-Heinemann. This book was released on 2013-10-22 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Cardiovascular Physiology is designed primarily for students of medicine and physiology. This introductory text is mostly didactic in teaching style and it attempts to show that knowledge of the circulatory system is derived from experimental observations. This book is organized into 15 chapters. The chapters provide a fuller account of microvascular physiology to reflect the explosion of microvascular research and include a discussion of the fundamental function of the cardiovascular system involving the transfer of nutrients from plasma to the tissue. They also cover major advances in cardiovascular physiology including biochemical events underlying Starling's law of the heart, nonadrenergic, non-cholinergic neurotransmission, the discovery of new vasoactive substances produced by endothelium and the novel concepts on the organization of the central nervous control of the circulation. This book is intended to medicine and physiology students.

Download or read book How Tobacco Smoke Causes Disease written by and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Download or read book Postoperative Critical Care for Cardiac Surgical Patients written by Ali Dabbagh and published by Springer Science & Business Media. This book was released on 2013-11-29 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac surgical procedures are among the most common and most complicated forms of surgery worldwide and the postoperative period is characterized by complex challenges. Among the factors determining ultimate clinical outcome, postoperative critical care is of major importance. This book adopts a clinical approach in explaining and analyzing the course of clinical care in patients undergoing cardiac surgery. Since the postoperative clinical status is directly influenced by preoperative and intraoperative factors, the early chapters briefly examine preoperative issues and the intraoperative course of cardiac surgery, with particular attention to anesthesia and the process of cardiopulmonary bypass. Subsequent chapters primarily address the critical care of patients by means of an organ-oriented approach, which will enable the reader to use the text as a "cookbook" of cardiac intensive care. This book is intended for use in daily practice by cardiac surgeons, cardiac anesthesiologists, intensivists and cardiac intensive care nurses.

Download or read book Clinical Methods written by Henry Kenneth Walker and published by Butterworth-Heinemann. This book was released on 1990 with total page 1128 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the techniques and analysis of clinical data. Each of the seventeen sections begins with a drawing and biographical sketch of a seminal contributor to the discipline. After an introduction and historical survey of clinical methods, the next fifteen sections are organized by body system. Each contains clinical data items from the history, physical examination, and laboratory investigations that are generally included in a comprehensive patient evaluation. Annotation copyrighted by Book News, Inc., Portland, OR