Download or read book Contribution of Extended Family History in Assessment of Risk for Breast and Colon Cancer written by Newark Newark Press and published by . This book was released on 2017-07-25 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt: Family history is important for identifying candidates for high risk cancer screening and referral for genetic counseling. We sought to determine the percentage of individuals who would be eligible for high risk cancer screening or genetic referral and testing if family history includes an extended (vs limited) family history. Proceeds from the sale of this book go to support an elderly disabled person.
Download or read book Medical Genetics of Colorectal Cancer written by Garden Grove Garden Grove Press and published by . This book was released on 2017-03-25 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: This article collection reviews the medical genetics of colorectal cancer and includes 25 papers by various authors. Topics include: The genetic basis of colonic adenomatous polyposis syndromes; Familial Adenomatous Polyposis (FAP) and Other Polyposis Syndromes; HNPCC (Lynch Syndrome): Differential Diagnosis, Molecular Genetics and Management - a Review; How does genetic risk information for Lynch syndrome translate to risk management behaviours?; Obesity and colorectal cancer: molecular features of adipose tissue; Molecular genetics of microsatellite-unstable colorectal cancer for pathologists; Genetic instability and increased mutational load: which diagnostic tool best direct patients with cancer to immunotherapy?; Novel germline MSH2 mutation in lynch syndrome patient surviving multiple cancers; Predictors of patient uptake of colorectal cancer gene environment risk assessment; EPHB2 germline variants in patients with colorectal cancer or hyperplastic polyposis; Molecular profile and copy number analysis of sporadic colorectal cancer in Taiwan; The multidrug resistance 1 (MDR1) gene polymorphism G-rs3789243-A is not associated with disease susceptibility in Norwegian patients with colorectal adenoma and colorectal cancer; a case control study; Cost-utility analysis of genetic screening in families of patients with germline MUTYH mutations; Microsatellite instability analysis in hereditary non-polyposis colon cancer using the Bethesda consensus panel of microsatellite markers in the absence of proband normal tissue; Contribution of extended family history in assessment of risk for breast and colon cancer; Genomic landscape of colorectal cancer in Japan: clinical implications of comprehensive genomic sequencing for precision medicine; Colorectal Cancer in the Family: Psychosocial Distress and Social Issues in the Years Following Genetic Counselling; Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases; A Comparison Between Denaturing Gradient Gel Electrophoresis and Denaturing High Performance Liquid Chromatography in Detecting Mutations in Genes Associated with Hereditary Non-Polyposis Colorectal Cancer (HNPCC) and the Identification of 9 New Mutations Previously Unidentified by DGGE; Molecular pathogenesis of sporadic colorectal cancers; Aberrant DNA methylation profiles of inherited and sporadic colorectal cancer; A genome wide association study on Newfoundland colorectal cancer patients' survival outcomes; mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancer; Mutation spectrum in human colorectal cancers and potential functional relevance; Altered pathways and colorectal cancer prognosis. Proceeds from the sale of this book go to the support of an elderly disabled person.
Download or read book Colorectal Cancer Screening An Issue of Gastrointestinal Endoscopy Clinics written by Douglas K. Rex and published by Elsevier Health Sciences. This book was released on 2020-06-21 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Together with Consulting Editor, Dr. Charles Lightdale, Dr. Doug Rex has put together an issue of Gastrointestinal Endoscopy Clinics that provides state-of-the-art clinical coverage of colorectal screening. Expert authors from all over the world have contributed clinical reviews that will be a staple for all practicing endoscopists. The articles are devoted to the following topics: What is organized screening and what is its value; Screening decisions in the opportunistic setting; The National Colorectal Cancer Round Table: Past performance and current and future goals; Proven strategies for increasing screening adherence; Colorectal cancer in persons under age 50: Seeking causes and solutions; Risk stratification strategies: From logistic regression to artificial intelligence; Cost-effectiveness of current screening tests; Quality in colorectal cancer screening; Screening for the serrated pathway; FIT: The world's colorectal cancer screening test; Fecal DNA testing: What has it accomplished and where is it headed; Is bowel preparation without complete colon clearing a viable concept: Update on flexible sigmoidoscopy, CTC, and capsule colonoscopy; Evidenced based screening strategies for a positive family history; Aspirational ADR and ideal colonoscopy performance: How long can we go between colonoscopies; and How Artificial Intelligence will impact colonoscopy and colorectal cancer screening. Readers will come away with the clinical knowledge they need to improve outcomes in colon cancer screening and prevention.
Download or read book Contribution of Family History in Women with High Risk Breast Cancer written by Ariela D. Ostrovsky and published by . This book was released on 1998 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genetics of Colorectal Cancer written by John D. Potter and published by Springer. This book was released on 2008-12-08 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic susceptibility refers to how variations in a person’s genes increase or decrease his or her susceptibility to environmental factors, such as chemicals, radiation and lifestyle (diet and smoking). This volume will explore the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers. Topics will include germline susceptibility, including Mendelian patterns of inheritance and gene-environment interactions that lead to cancer etiology.
Download or read book Collection and Use of Cancer Family History in Primary Care written by Nadeem Qureshi and published by DIANE Publishing. This book was released on 2009-05 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: This systematic review was undertaken to: (1) evaluate the accuracy of patient reporting of cancer family history; (2) identify and evaluate tools designed to capture cancer family history that are applicable to the primary care setting; and (3) identify and evaluate risk assessment tools (RATs) in promoting appropriate management of familial cancer risk in primary care settings. For family history tools (FHxTs) and RATs, studies were limited to those applicable to primary care settings. Conclusions: Informants reporting their cancer family history have greater accuracy for relatives free of cancer than those with cancer. Reporting accuracy may vary among different cancer types. Charts and tables.
Download or read book Hereditary Breast Ovarian and Colon Cancer written by and published by . This book was released on 1995 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fulfilling the Potential of Cancer Prevention and Early Detection written by National Research Council and published by National Academies Press. This book was released on 2003-05-07 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer ranks second only to heart disease as a leading cause of death in the United States, making it a tremendous burden in years of life lost, patient suffering, and economic costs. Fulfilling the Potential for Cancer Prevention and Early Detection reviews the proof that we can dramatically reduce cancer rates. The National Cancer Policy Board, part of the Institute of Medicine, outlines a national strategy to realize the promise of cancer prevention and early detection, including specific and wide-ranging recommendations. Offering a wealth of information and directly addressing major controversies, the book includes: A detailed look at how significantly cancer could be reduced through lifestyle changes, evaluating approaches used to alter eating, smoking, and exercise habits. An analysis of the intuitive notion that screening for cancer leads to improved health outcomes, including a discussion of screening methods, potential risks, and current recommendations. An examination of cancer prevention and control opportunities in primary health care delivery settings, including a review of interventions aimed at improving provider performance. Reviews of professional education and training programs, research trends and opportunities, and federal programs that support cancer prevention and early detection. This in-depth volume will be of interest to policy analysts, cancer and public health specialists, health care administrators and providers, researchers, insurers, medical journalists, and patient advocates.
Download or read book The Role of Family Organization in Family Health History Communication about Cancer written by Vivian M. Rodríguez and published by . This book was released on 2013 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Family health history (FHH) has been recognized as an important tool in cancer prevention and health promotion. To date, literature on FHH discussions about cancer have largely focused on patient-physician communication or the dissemination of cancer-specific genetic tests results within the family. Fewer studies have sought to identify family factors that may promote FHH discussions, yet this type of information could be used to identify families needing support in having these conversations. Thus, the present study examined relations between family organization (cohesion and flexibility), communication openness, and FHH communication about cancer within a diverse group of women recruited from an urban, safety-net women's health clinic. Participants were enrolled in a randomized control trial examining the effects of an educational intervention on family communication about hereditary breast and colon cancers (Kin Fact Study). For the present study, baseline survey data for 472 women were analyzed. Participants completed measures on demographics, family organization, communication openness, and FHH communication. Average age was 34 years and 59% reported being Black. Thirty-one percent had graduated high school and 28% reported having commercial health insurance. Seventy-five percent of women reported a family history of cancer in a first or second degree relative. Descriptive statistics, correlations, and multiple linear regression and hierarchical logistic regressions, adjusting for key factors, were performed. Nineteen percent of women actively collected FHH information about cancer and 11% reported actively sharing cancer risk information with relatives. Being older, having a greater educational attainment, and having a family history of cancer was associated with having collected FHH; while being older and reporting higher levels of cohesion/flexibility was associated with sharing cancer risk information. Adjusting for demographic variables, cohesion, flexibility, and openness were not significant predictors of collecting or sharing FHH. Family history of cancer did not moderate the relationship between family organization and FHH. Cohesion and flexibility levels did significantly predict communication openness. This study contributes to a small but emergent literature in the field of FHH communication about cancer as it explores family context factors that may aid in the development of prevention interventions. Clinical implications and directions for future research are discussed.
Download or read book Oncological Surgical Pathology written by Cesar A. Moran and published by Springer Nature. This book was released on 2020-01-29 with total page 2209 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides the necessary tools and up-to-date information on the morphological approach and most current use of ancillary techniques in the diagnosis and treatment of malignant tumors. The work is divided by sub specialty areas so that the reader can easily obtain the information desired. Features of histopathological lesions are presented in each area, as well as an up-to-date use of the different immunohistochemical stains and molecular biology features, when applicable, which are commonly used to determine treatment modalities. All sub specialty sections are written by sub specialty pathologists with experience in tumor pathology and who work in a cancer center. Each chapter is richly illustrated and properly referenced. Oncological Surgical Pathology will be of use not only for pathologists (including pathology residents and fellows), but also for oncological surgeons, oncologists and interventional radiologists.
Download or read book Colorectal Cancer Screening written by Joseph Anderson, MD and published by Springer Science & Business Media. This book was released on 2011-04-23 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal Cancer Screening provides a complete overview of colorectal cancer screening, from epidemiology and molecular abnormalities, to the latest screening techniques such as stool DNA and FIT, Computerized Tomography (CT) Colonography, High Definition Colonoscopes and Narrow Band Imaging. As the text is devoted entirely to CRC screening, it features many facts, principles, guidelines and figures related to screening in an easy access format. This volume provides a complete guide to colorectal cancer screening which will be informative to the subspecialist as well as the primary care practitioner. It represents the only text that provides this up to date information about a subject that is continually changing. For the primary practitioner, information on the guidelines for screening as well as increasing patient participation is presentedd. For the subspecialist, information regarding the latest imaging techniques as well as flat adenomas and chromoendoscopy are covered. The section on the molecular changes in CRC will appeal to both groups. The text includes up to date information about colorectal screening that encompasses the entire spectrum of the topic and features photographs of polyps as well as diagrams of the morphology of polyps as well as photographs of CT colonography images. Algorithms are presented for all the suggested guidelines. Chapters are devoted to patient participation in screening and risk factors as well as new imaging technology. This useful volume explains the rationale behind screening for CRC. In addition, it covers the different screening options as well as the performance characteristics, when available in the literature, for each test. This volume will be used by the sub specialists who perform screening tests as well as primary care practitioners who refer patients to be screened for colorectal cancer.
Download or read book Managing Health in the Genomic Era written by Vincent Henrich and published by Academic Press. This book was released on 2020-06-27 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Managing Health in the Genomic Era: A Guide to Family Health History and Disease Risk, Drs. Vincent C. Henrich, Lori A. Orlando, and Brian H. Shirts discuss the practical considerations surrounding the use of genomic and genetic tests to manage patient health, to provide adult disease risk assessment, to improve diagnosis, and to support effective interventions and treatment. In 10 chapters, evidence-based information and case studies are described and examine the central place of family health history (FHH) in genomic medicine, tools and strategies for compiling and analyzing family health history, how to identify existing and novel genetic markers, how to identify lineage specific (or rare) variants within families, and how to find effective interventions based on genetic testing results and FHH. Factors that influence clinical practice, including gene-environment interactions, FHH social networking, direct to consumer (DTC) genetic testing and data sharing, algorithms for analyzing genetic data, and patient counseling are discussed from the standpoint of clinical practice. Here, frontline healthcare providers will discover succinct commentary and key examples to assist with their local needs. Relevant principles of genetic biology and inheritance are explored and guidance on available support networks and online resources is also provided. - 2021 PROSE Awards - Winner: Category: Clinical Medicine: Association of American Publishers - Presents a practical, accessible resource for primary care providers, allied health professionals, pharmacologists, public health professionals, students and clinical researchers - Addresses genetic and genomic approaches in managing patient health, conducting and analyzing family health histories, and assessing adult disease risk - Features an expert author team with direct experience integrating genetics and genomics in primary care and family medicine settings - Examines the attributes and limitations of family health history, genetic testing, and genomic testing in clinical practice - Includes detailed explanations following practice-based examples
Download or read book Hereditary Colorectal Cancer written by Miguel A. Rodriguez-Bigas and published by Springer Science & Business Media. This book was released on 2010-09-10 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. The national annual incidence rate of colorectal cancer is approximately 148,000+, striking slightly more females than males. The lifetime risk of colorectal cancer is 5-6%, however patients with a familial risk (with two or more first or second degree relatives) make up 20% of the patients. Persons who carry genetic mutations linked to hereditary colorectal cancer are the most likely to develop the disease.
Download or read book Prevention and Early Detection of Colorectal Cancer written by Graeme P. Young and published by W.B. Saunders Company. This book was released on 1996 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an overview of the issues involved in prevention and early detection of colorectal cancer providing up-to-date, practical advice for clinicians. Possible management strategies for those at risk are provided, taking into account the biological principles of colorectal cancer development, epidemiological data and emerging genetic information, as well as social and environmental factors.
Download or read book Clinical Case Studies for the Family Nurse Practitioner written by Leslie Neal-Boylan and published by John Wiley & Sons. This book was released on 2011-11-28 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Case Studies for the Family Nurse Practitioner is a key resource for advanced practice nurses and graduate students seeking to test their skills in assessing, diagnosing, and managing cases in family and primary care. Composed of more than 70 cases ranging from common to unique, the book compiles years of experience from experts in the field. It is organized chronologically, presenting cases from neonatal to geriatric care in a standard approach built on the SOAP format. This includes differential diagnosis and a series of critical thinking questions ideal for self-assessment or classroom use.
Download or read book Hereditary Colorectal Cancer written by Laura Valle and published by Springer. This book was released on 2018-05-04 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides information on a wide variety of issues ranging from genetics to clinical description of the syndromes, genetic testing and counseling, and clinical management including surveillance, surgical and prophylactic interventions, and chemoprevention. Moreover, current hot issues, such as the identification of novel causal genes and the challenges we face, and the relevance of cancer risk modifiers, both genetic and environmental, are also discussed. This reference book is great for geneticists, oncologists, genetic counselors, researchers, clinicians, surgeons and nurses dedicated to, or interested in, hereditary cancer. The best and most recognized experts in the field have contributed to this project, guaranteeing updated information, accuracy and the discussion of topical issues.
Download or read book Cancer Associated Thrombosis written by Alok A. Khorana and published by CRC Press. This book was released on 2007-09-26 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides
