Download or read book Continuous Microfluidic Reactors for Polymer Particles written by Minseok Seo and published by . This book was released on 2008 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this thesis, we present a versatile new method for preparing highly monodisperse droplets, polymer particles, double emulsions, and self-assemblies of droplets in continuous microfluidic reactors. Recently, microfluidic systems are significantly being used in many areas of chemistry and biotechnology to achieve improved performance. Microfluidics provides the ability to automate highly repetitive laboratory tasks by replacing huge cumbersome equipment with miniaturized and integrated systems, and it enables the handling of small amounts, e.g., from microliters to femtoliters of fluids, reactants and products. These methods have the following useful features: (1) the generation of extremely monodisperse droplets, (2) the generation and control of both the shape and the size of the droplets, (3) the use of a wide variety of materials, including: gels, monomers, polymers, copolymers, and polymers doped with functional additives, (4) a possibility of in situ solidification of the droplets by means of photopolymerization and/or thermopolymerization, and (5) the ability to scale up the production of large quantities of particles. We focus on the effect of the properties of the disperse and continuous phases on the emulsification process, the effect of the polymerization rate on the production of high-quality particles, the role of the material and geometry of the microfluidic device in droplet formation, and the synthesis of particles with different shapes and compositions.
Download or read book Microfluidic Reactors for Polymer Particles written by Eugenia Kumacheva and published by John Wiley & Sons. This book was released on 2011-02-14 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: The manipulation of fluids in channels with dimensions in the range from tens to hundreds of micrometers – microfluidics – has recently emerged as a new field of science and technology. Microfluidics has applications spanning analytical chemistry, organic and inorganic synthesis, cell biology, optics and information technology. One particularly promising application is the microfluidic synthesis of polymer particles with precisely controlled dimensions, and a variety of shapes, morphologies and compositions. Written as a comprehensive introduction for scientists and engineers working in microfabrication and microfluidics, Microfluidic Reactors for Polymer Particles covers topics such as: Applications and methods of generation of polymer particles Physics of microfluidic emulsification Formation of droplets in microfluidic systems High-throughput microfluidic systems for formation of droplets Microfluidic production of polymer particles and hydrogel particles Polymer capsules Synthesis of polymer particles with non-conventional shapes This book is intended for a broad audience, including students, researchers and engineers in industry, with interests in physics, chemistry, materials science, engineering or biotechnology.
Download or read book Microchemical Engineering in Practice written by Thomas Dietrich and published by John Wiley & Sons. This book was released on 2011-11-18 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microchemical Engineering in Practice provides the information chemists and engineers need to evaluate the use of microreactors, covering the technical, operational, and economic considerations for various applications. It explains the systems needed to use microreactors in production and presents examples of microreactor use in different chemistries, including larger scale production processes. There are guidelines on calculating the costs and the risks of production using continuous flow microreactors. Complete with case studies, this is an essential guide for chemists and engineers interested in investigating the advantages of chemical microreactors.
Download or read book Polymer Reaction Engineering of Dispersed Systems written by Werner Pauer and published by Springer. This book was released on 2018-11-19 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Advances in Polymer Science presents critical reviews of the present and future trends in polymer and biopolymer science. It covers all areas of research in polymer and biopolymer science including chemistry, physical chemistry, physics, material science.The thematic volumes are addressed to scientists, whether at universities or in industry, who wish to keep abreast of the important advances in the covered topics.Advances in Polymer Science enjoys a longstanding tradition and good reputation in its community. Each volume is dedicated to a current topic, and each review critically surveys one aspect of that topic, to place it within the context of the volume. The volumes typically summarize the significant developments of the last 5 to 10 years and discuss them critically, presenting selected examples, explaining and illustrating the important principles, and bringing together many important references of primary literature. On that basis, future research directions in the area can be discussed. Advances in Polymer Science volumes thus are important references for every polymer scientist, as well as for other scientists interested in polymer science - as an introduction to a neighboring field, or as a compilation of detailed information for the specialist.Review articles for the individual volumes are invited by the volume editors. Single contributions can be specially commissioned.Readership: Polymer scientists, or scientists in related fields interested in polymer and biopolymer science, at universities or in industry, graduate students
Download or read book Nanotechnologies for Solubilization and Delivery in Foods Cosmetics and Pharmaceuticals written by Nissim Garti and published by DEStech Publications, Inc. This book was released on 2012 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beginning with the basics of surfactant chemistry and micellization, this book presents a range of nanotechnology strategies for controlling colloidal and polymeric structures for the solubilization and targeted delivery of food nutrients and pharmaceuticals.
Download or read book Nanoscience written by Victor M. Starov and published by CRC Press. This book was released on 2011-06-03 with total page 1610 pages. Available in PDF, EPUB and Kindle. Book excerpt: The common perception is that nanoscience is something entirely new, that it sprung forth whole and fully formed like some mythological deity. But the truth is that like all things scientific, nanoscience is the natural result of the long evolution of scientific inquiry. Following a historical trail back to the middle of the 19th century, nanoscience is the inborn property of colloid and interface science. What’s important today is for us to recognize that nanoparticles are small colloidal objects. It should also be appreciated that over the past decades, a number of novel nanostructures have been developed, but whatever we call them, we cannot forget that their properties and behavior are still in the realm of colloid and interface science. However one views it, the interest and funding in nano-science is a tremendous opportunity to advance critical research in colloid chemistry. Nanoscience: Colloidal and Interfacial Aspects brings together a prominent roster of 42 leading investigators and their teams, who detail the wide range of theoretical and experimental knowledge that can be successfully applied for investigating nanosystems, many of which are actually well-known colloidal systems. This international grouping of pioneering investigators from academia and industry use these pages to provide researchers of today and tomorrow with a full examination of nano-disperse colloids, homogeneous and heterogeneous nano-structured materials (and their properties), and shelf-organization at the nano-scale. This cutting-edge reference provides information on investigations into non-linear electrokinetic phenomena in nano-sized dispersions and nano-sized biological systems. It discusses application aspects of technological processes in great detail, providing scientists and engineers across all fields with authoritative commentary on colloid and interface science operating at the nanoscale. Nano-Science: Colloidal and Interfacial Aspects provides an authoritative resource for those wanting to familiarize themselves with current progress as well as for those looking to make their own impact on the development of new technologies and practical applications in fields as diverse as medicine, materials, and environmental science to name but a few. Whether you call the technology nano or colloids, the field continues to be ripe with opportunity.
Download or read book Micro Drops and Digital Microfluidics written by Jean Berthier and published by William Andrew. This book was released on 2012-12-31 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this 2nd edition of Micro-Drops and Digital Microfluidics, Jean Berthier explores the fundamentals and applications of digital microfluidics, enabling engineers and scientists to design this important enabling technology into devices and harness the considerable potential of digital microfluidics in testing and data collection. This book describes the most recent developments in digital microfluidics, with a specific focus on the computational, theoretical and experimental study of microdrops. Unique in its emphasis on digital microfluidics and with diverse applications ranging from drug delivery to point-of-care diagnostic chips, organic synthesis to microreactors, Micro-Drops and Digital Microfluidics meets the needs of audiences across the fields of bioengineering and biotechnology, and electrical and chemical engineering. Authoritative reporting on the latest changes in microfluidic science, where microscopic liquid volumes are handled as ""microdrops"" and separately from ""nanodrops." A methodical examination of how liquid microdrops behave in the complex geometries of modern miniaturized systems and interact with different morphological (micro-fabricated, textured) solid substrates A thorough explanation of how capillary forces act on liquid interfaces in contact with micro-fabricated surfaces Analysis of how droplets can be manipulated, handled, or transported using electric fields (electrowetting), acoustic actuation (surface acoustic waves), or by a carrier liquid (microflow) A fresh perspective on the future of microfluidics
Download or read book Accounts on Sustainable Flow Chemistry written by Timothy Noël and published by Springer Nature. This book was released on 2020-01-23 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
Download or read book Microdroplet Technology written by Philip Day and published by Springer Science & Business Media. This book was released on 2012-07-28 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microdroplet technology has recently emerged to provide new and diverse applications via microfluidic functionality, especially in various areas of biology and chemistry. This book, then, gives an overview of the principle components and wide-ranging applications for state-of-the-art of droplet-based microfluidics. Chapter authors are internationally-leading researchers from chemistry, biology, physics and engineering that present various key aspects of micrdroplet technology -- fundamental flow physics, methodology and components for flow control, applications in biology and chemistry, and a discussion of future perspectives. This book acts as a reference for academics, post-graduate students, and researcher wishing to deepen their understand of microfluidics and introduce optimal design and operation of new droplet-based microfluidic devices for more comprehensive analyte assessments.
Download or read book Microfluidic Devices in Nanotechnology written by Challa S. S. R. Kumar and published by John Wiley & Sons. This book was released on 2010-11-29 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explores the latest applications arising from the intersection of nanotechnology and microfluidics In the past two decades, microfluidics research has seen phenomenal growth, with many new and emerging applications in fields ranging from chemistry, physics, and biology to engineering. With the emergence of nanotechnology, microfluidics is currently undergoing dramatic changes, embracing the rising field of nanofluidics. This volume reviews the latest devices and applications stemming from the merging of nanotechnology with microfludics in such areas as drug discovery, bio-sensing, catalysis, electrophoresis, enzymatic reactions, and nanomaterial synthesis. Each of the ten chapters is written by a leading pioneer at the intersection of nanotechnology and microfluidics. Readers not only learn about new applications, but also discover which futuristic devices and applications are likely to be developed. Topics explored in this volume include: New lab-on-a-chip systems for drug delivery Integration of microfluidics with nanoneuroscience to study the nervous system at the single-cell level Recent applications of nanoparticles within microfluidic channels for electrochemical and optical affinity biosensing Novel microfluidic approaches for the synthesis of nanomaterials Next-generation alternative energy portable power devices References in each chapter guide readers to the primary literature for further investigation of individual topics. Overall, scientists, researchers, engineers, and students will not only gain a new perspective on what has been done, but also the nanotechnology tools they need to develop the next generation of microfluidic devices and applications. Microfluidic Devices for Nanotechnology is a two-volume publication, the first ever to explore the synergies between microfluidics and nanotechnology. The first volume covers fundamental concepts; this second volume examines applications.
Download or read book Nano and Microfabrication Techniques in Drug Delivery written by Dimitrios Lamprou and published by Springer Nature. This book was released on 2023-04-27 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: New materials and manufacturing techniques are evolving with the potential to address the challenges associated with the manufacture of medicinal products that will teach new tricks to old drugs. Nano- and microfabrication techniques include manufacturing methods such as additive manufacturing, lithography, micro-moulding, spray drying, and supercritical fluids among many others. The increasing resolution of new techniques allow researchers to produce objects with micrometric resolutions. This book follows a consecutive order, beginning with a background in the current field and limitations in the manufacturing of different pharmaceutical products, moving on the classification of each method by providing recent examples, and future prospective on a variety of traditional and new Nano and microfabrication techniques. A focus on the materials used to prepare these systems and their biocompatibility, including applied topics such as clinical applications and regulatory aspects also covered, offering the reader a holistic view of this rapidly growing field.
Download or read book Multiple Emulsion written by Abraham Aserin and published by John Wiley & Sons. This book was released on 2007-11-12 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Comprehensive, Single-Source Reference on Multiple Emulsions In theory, multiple emulsions have significant potential for breakthrough applications in food, agricultural, pharmaceutical, nutraceutical, and cosmetic industries in which they can facilitate the sustained release and transport of active material. However, in practice, multiple emulsions are thermodynamically unstable. This book presents recent findings that can help formulators understand how to enhance their stability. With chapters contributed by leading experts from around the world, it covers the definition and properties of multiple emulsions, their formation and stability, and potential applications, with an emphasis on medical and pharmaceutical applications. In one definitive resource, it presents recent findings and achievements in the field, including: New theoretical approaches and modeling to characterize the transport mechanism Droplet size reduction and increased shelf life stability through the use of polymeric amphiphiles and complex adducts The use of new emulsification techniques to enhance the monodispersibility of the droplets Potential applications in drug delivery systems where clinical studies have proven their efficacy This is a core, hands-on reference for surface and colloid scientists, physical chemists, chemical engineers, soft materials scientists, food chemists, controlled release scientists, and pharmaceutical scientists in drug delivery applications, as well as for graduate students in these disciplines. The editor and contributors hope this logical consolidation of current information will further the understanding of multiple emulsions and lead to new, practical applications.
Download or read book The Delivery of Nanoparticles written by Abbass A. Hashim and published by BoD – Books on Demand. This book was released on 2012-05-16 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoparticle is a general challenge for today's technology and the near future observations of science. Nanoparticles cover mostly all types of sciences and manufacturing technologies. The properties of this particle are flying over today scientific barriers and have passed the limitations of conventional sciences. This is the reason why nanoparticles have been evaluated for the use in many fields. InTech publisher and the contributing authors of this book in nanoparticles are all overconfident to invite all scientists to read this new book. The book's potential was held until it was approached by the art of exploring the most advanced research in the field of nano-scale particles, preparation techniques and the way of reaching their destination. 25 reputable chapters were framed in this book and there were alienated into four altered sections; Toxic Nanoparticles, Drug Nanoparticles, Biological Activities and Nano-Technology.
Download or read book Encapsulation and Controlled Release Technologies in Food Systems written by Dr Jamileh M. Lakkis and published by John Wiley & Sons. This book was released on 2016-03-09 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence of the discipline of encapsulation and controlled release has had a great impact on the food and dietary supplements sectors; principally around fortifying food systems with nutrients and health-promoting ingredients. The successful incorporation of these actives in food formulations depends on preserving their stability and bioavailability as well as masking undesirable flavors throughout processing, shelf life and consumption. This second edition of Encapsulation and Controlled Release Technologies in Food Systems serves as an improvement and a complement companion to the first. However, it differentiates itself in two main aspects. Firstly, it introduces the reader to novel encapsulation and controlled release technologies which have not yet been addressed by any existing book on this matter, and secondly, it offers an in-depth discussion on the impact of encapsulation and controlled release technologies on the bioavailability of health ingredients and other actives. In common with the first edition the book includes chapters written by distinguished authors and researchers in their respective areas of specialization. This book is designed as a reference for scientists and formulators in the food, nutraceuticals and consumer products industries who are looking to formulate new or existing products using microencapsulated ingredients. It is also a post-graduate text designed to provide students with an introduction to encapsulation and controlled release along with detailed coverage of various encapsulation technologies and their adaptability to specific applications.
Download or read book Microfluidic assisted Synthesis and Release Properties of Multi domain Polymer Microparticles Drug Carriers written by Ikram Ullah Khan and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Characteristics and release properties of drug loaded microparticles depend upon material used and choice of production method. Conversely to most of the conventional ones, microfluidic methods give an edge by improving the control over droplet generation, size and size distribution. Capillary-based microfluidic devices were successfully used to obtain monodisperse drug(s) loaded microbeads, janus, core-shell and trojan particles using UV initiated free radical polymerization while keeping activity of active loaded molecules. These devices can be assembled in a short period of time and a slight change in design gives completely different microparticles morphologies. These particles were developed with the aim to address different issues experienced in oral drug delivery. For instance microbeads can be used to deliver NASIDs in a sustained release manner while janus particles can release two APIs with completely different properties (solubility, compatibility) also in a sustained release manner. Core-shell particles were designed to target colonic region of human intestine for dual drug delivery. Trojan particles were synthesized in a new semi-continuous microfluidic process, thus improving nanoparticles safety handling and release in simulated gastric fluid. Each system was fully characterized to insure batch to batch consistency and reproducibility. In general, the release of active ingredients was controlled by tuning the operating and material parameters like phases flow rates, nature and concentration of drug, (co)monomers, surfactant and crosslinker, pH of release media with the result of different particle morphologies, sizes and shapes or matrix crosslinking density.
Download or read book Biomedical Nanomaterials written by Yuliang Zhao and published by John Wiley & Sons. This book was released on 2016-12-12 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book discusses in a detailed manner various nanomaterials used for biomedical applications, including clinical applications, diagnosis and tissue engineering. After the presentation of an overview of biomedical nanomaterials, including their classification and applications, the first part of the book is devoted to biomedical nanomaterials for therapy applications. For example, polymer micelles, dendrimers, polymer-drug conjugates as well as antibody-drug conjugates are discussed with respect to their cancer drug delivery properties. The next parts discuss biomedical nanomaterials that are used for imaging, diagnosis and sensors, as well as for tissue engineering. In the final section, the safety of biomedical nanomaterials is elaborated.
Download or read book Microfluidics for Advanced Functional Polymeric Materials written by Liang-Yin Chu and published by John Wiley & Sons. This book was released on 2017-06-19 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and systematic treatment of our current understanding of the microfluidic technique and its advantages in the controllable fabrication of advanced functional polymeric materials. Introducing and summarizing recent advances and achievements in the field, the authors cover the design and fabrication of microfluidic devices, the fundamentals and strategies for controllable microfluidic generation of multiphase liquid systems, and the use of these liquid systems with an elaborate combination of their structures and compositions for generating novel polymer materials, such as microcapsules, microfibers, valves, and membranes. Clear diagrams and illustrations throughout the text make the relevant theory and technologies more readily accessible. The result is a specialist reference for materials scientists, organic, polymer and physical chemists, and chemical engineers.