Download or read book Contemporary Metabolism written by Norbert Freinkel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite a new title, Contemporary Metabolism, Volume 1 is actually the third volume in a continuing series and succeeds The Year in Metabolism 1975- 1976 and The Year in Metabolism 1977. As in the earlier volumes, the same internationally recognized authorities review the noteworthy recent devel opments in their areas of expertise. In many instances they also address aspects that have not been considered previously. In this volume, Dr. J. Edwin Seegmiller again updates progress in understanding disorders of purine and pyrimidine metabolism. However, particular emphasis is placed on the emerging relationships with immune mechanisms. Dr. Charles S. Lieber is joined by Dr. Enrique Baraona in a continuing review of metabolic actions of ethanol. This chapter examines effects of ethanol on protein metabolism and selected features of lipid metabolism-two areas that were not included in the earlier volumes. Dr. DeWitt S. Goodman's review of disorders oflipid and lipoprotein metabo lism builds on his previous chapters, but much additional attention is directed to a critical analysis of recent advances in epidemiology and lipoprotein structures. In collaboration with Dr. Brian L. G. Morgan, Dr. Myron Winick devotes his entire chapter to a detailed review of the impact of nutrition upon brain development-an overview that has now been rendered possible by the burgeoning recent developments in this area.
Download or read book Kenzo Tange and the Metabolist Movement written by Zhongjie Lin and published by Routledge. This book was released on 2010-02-25 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolism, the Japanese architectural avant-garde movement of the 1960s, profoundly influenced contemporary architecture and urbanism. This book focuses on the Metabolists’ utopian concept of the city and investigates the design and political implications of their visionary planning in the postwar society. At the root of the group’s urban utopias was a particular biotechical notion of the city as an organic process. It stood in opposition to the Modernist view of city design and led to such radical design concepts as marine civilization and artificial terrains, which embodied the metabolists’ ideals of social change. Tracing the evolution of Metabolism from its inception at the 1960 World Design Conference to its spectacular swansong at the Osaka World Exposition in 1970, this book situates Metabolism in the context of Japan’s mass urban reconstruction, economic miracle, and socio-political reorientation. This new study will interest architectural and urban historians, architects and all those interested in avant-garde design and Japanese architecture.
Download or read book Bioinformatics of Genome Evolution from Ancestral to Modern Metabolism Phylogenomics and Comparative Genomics to Understand Microbial Evolution written by Marco Fondi and published by Firenze University Press. This book was released on 2011 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics, that is the interdisciplinary field that blends computer science and biostatistics with biological and biomedical sciences, is expected to gain a central role in next feature. Indeed, it has now affected several fields of biology, providing crucial hints for the understanding of biological systems and also allowing a more accurate design of wet lab experiments. In this work, the analysis of sequence data has be used in different fields, such as evolution (e.g. the assembly and evolution of metabolism), infections control (e.g. the horizontal flow of antibiotic resistance), ecology (bacterial bioremediation).
Download or read book Contemporary Metabolism written by Norbert Freinkel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is abundantly clear that a number of subtle abnormalities in hypothalamic function are associated with human obesity. Some hormonal abnormalities-the diminished growth hormone responses, for example-are critically dependent on increased caloric intake and are quickly reversible with weight loss. Others, such as the blunted prolactin response to acute hypoglycemia, may persist in the reduced-obese state. Still others (e. g. , the blunted ACTH responses to insulin induced hypoglycemia) may, in some patients, first appear in the reduced-obese state. It remains uncertain whether any of these abnormalities is ever antecedent to the presence of obesity. Obviously, it is difficult to plan experiments in which the amounts of stored triglyceride, the level of caloric intake, and the state or his tory of obesity can all be individually evaluated. The issue is made even more complex by the fact that there may be subgroups of obese in whom hypothalamic function may be abnormal, whereas many obese may have nearly normal hypo thalamic function. It should be remembered that for years clinicians and investigators, working with available research tools, have ruled out pituitary or hypothalamic abnor malities as a cause of human obesity. These tools have oftentimes been no more sophisticated than skull roentgenograms and samples of excreted steroid hormones in 24-hr urine. The advent of radioimmunoassays for peptide hormones and the availability of synthetic releasing hormones have offered possibilities of studying hypothalamic function undreamed of just a few years ago.
Download or read book New Urban Metabolism written by Josep Antoni Acebillo and published by ACTAR Publishers. This book was released on 2012 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The iCUP (Institute for Contemporary Urban Project) is the institute, directed by ... Acebillo and coordinated by ... Enrico Sassi, within which this book has been produced and it is part of the Accademia di architettura, USI (Universita della Svizzera Italiana), Mendrisio"--Page 6.
Download or read book Contemporary Metabolism written by and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Insulin Resistance written by Gerald M. Reaven and published by Springer Science & Business Media. This book was released on 1999-04 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Insulin Resistance: The Metabolic Syndrome X, outstanding investigators thoughtfully summarize our current understanding of how insulin resistance and its compensating hyperinsulinemia (Syndrome X) play a major role in the pathogenesis and clinical course of high blood pressure and cardiovascular disease-the so-called diseases of Western civilization-as well as polycystic ovary disease. Under the aegis of Gerald Reaven, the discoverer of Syndrome X, the distinguished authorities writing here detail for the first time the pathophysiological consequences and the clinical syndromes, excluding Type 2 diabetes, related to insulin resistance. They also examine the genetic and lifestyle factors that contribute to the wide differences in insulin action that exist in the population at large. Each author has been encouraged to present a point of view that reflects their unique insights. The first authoritative book on the subject, Insulin Resistance: The Metabolic Syndrome X illuminates the special importance of insulin resistance as a major cause of hypertension, heart disease, and polycystic ovary syndrome. Its thoughtful and detailed approach will make it an essential reference for basic and clinical researchers seeking to understand these critical phenomena.
Download or read book Metabolism in Architecture written by Kishō Kurokawa and published by . This book was released on 1977 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Even in a country where outstanding achievements have become almost a commonplace, the Japanese architect, Kisho Kurokawa, appears as both a remarkable and a remarkably successful man. With buildings in the United States and Eastern and Western Europe as well as in Japan, he has established an international reputation as a leading figure amongst the younger generation of architects. At the age of forty he already had thirty-five major buildings and seventeen books to his credit; four new towns are being built to his designs; he heads a company of over a hundred employees, he runs a think-tank and an urban design bureau and for variety he has his own television programme with a regular audience of some 30 million. Behind these statistics lies a prodigious vitality expressed in original and stimulating buildings. -- from book jacket.
Download or read book The Metabolist Imagination written by William O. Gardner and published by U of Minnesota Press. This book was released on 2020-04-14 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Japan’s postwar urban imagination through the Metabolism architecture movement and visionary science fiction authors The devastation of the Second World War gave rise to imaginations both utopian and apocalyptic. In Japan, a fascinating confluence of architects and science fiction writers took advantage of this space to begin remaking urban design. In The Metabolist Imagination, William O. Gardner explores the unique Metabolism movement, which allied with science fiction authors to foresee the global cities that would emerge in the postwar era. This first comparative study of postwar Japanese architecture and science fiction builds on the resurgence of interest in Metabolist architecture while establishing new directions for exploration. Gardner focuses on how these innovators created unique versions of shared concepts—including futurity, megastructures, capsules, and cybercities—making lasting contributions that resonate with contemporary conversations around cyberpunk, climate change, anime, and more. The Metabolist Imagination features original documentation of collaborations between giants of postwar Japanese art and architecture, such as the landmark 1970 Osaka Expo. It also provides the most sustained English-language discussion to date of the work of Komatsu Sakyō, considered one of the “big three” authors of postwar Japanese science fiction. These studies are underscored by Gardner’s insightful approach—treating architecture as a form of speculative fiction while positioning science fiction as an intervention into urban design—making it a necessary read for today’s visionaries.
Download or read book Contemporary Metabolism written by 3Island Press and published by . This book was released on 1982-06-30 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Project Japan written by Rem Koolhaas and published by . This book was released on 2011 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolism was a movement launched in Japan that took inspiration for buildings and cities from biological systems. With interviews and commentary and hundreds of images, Project Japan unearths a history that casts new light on the key issues that both enervate and motivate architecture today.
Download or read book Contemporary Japanese Architecture written by James Steele and published by Taylor & Francis. This book was released on 2017-03-16 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contemporary Japanese Architecture presents a clear and comprehensive overview of the historical and cultural framework that informs the work of all Japanese architects, as an introduction to an in-depth investigation of the challenges now occupying the contemporary designers who will be the leaders of the next generation. It separates out the young generation of Japanese architects from the crowded, distinguished, multi-generational field they seek to join, and investigates the topics that absorb them, and the critical issues they face within the new economic reality of Japan and a shifting global order. Salient points in the text are illustrated by beautiful, descriptive images provided by the architects and from the extensive collection of the author. By combining illustrations with timelines and graphics to explain complex ideas, the book is accessible to any student seeking to understand contemporary Japanese architecture.
Download or read book Handbook of Infrastructures and Cities written by Olivier Coutard and published by Edward Elgar Publishing. This book was released on 2024-04-12 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contributing towards a thriving research area, this comprehensive Handbook presents a broad discussion of infrastructure as social phenomena. It compiles diverse perspectives to delineate the current ‘infrastructural turn’ and assess policy and research challenges relating to contemporary forms of infrastructural development.
Download or read book Drug Metabolism in Drug Design and Development written by Donglu Zhang and published by John Wiley & Sons. This book was released on 2007-11-16 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: The essentials of drug metabolism vital to developing new therapeutic entities Information on the metabolism and disposition of candidate drugs is a critical part of all aspects of the drug discovery and development process. Drug metabolism, as practiced in the pharmaceutical industry today, is a complex, multidisciplinary field that requires knowledge of sophisticated analytical technologies and expertise in mechanistic and kinetic enzymology, organic reaction mechanism, pharmacokinetic analysis, animal physiology, basic chemical toxicology, preclinical pharmacology, and molecular biology. With chapters contributed by experts in their specific areas, this reference covers: * Basic concepts of drug metabolism * The role of drug metabolism in the pharmaceutical industry * Analytical techniques in drug metabolism * Common experimental approaches and protocols Drug Metabolism in Drug Design and Development emphasizes practical considerations such as the data needed, the experiments and analytical methods typically employed, and the interpretation and application of data. Chapters highlight facts, common protocols, detailed experimental designs, applications, and limitations of techniques. This is a comprehensive, hands-on reference for drug metabolism researchers as well as other professionals involved in pre-clinical drug discovery and development.
Download or read book Comparative Animal Nutrition and Metabolism written by Peter R. Cheeke and published by CABI. This book was released on 2010 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrition is a very broad discipline, encompassing biochemistry, physiology, endocrinology, immunology, microbiology and pathology. Presenting the major principles of nutrition of both domestic and wild animals, this book takes a comparative approach, recognising that there are considerable differences in nutrient digestion, metabolism and requirements among various mammalian and avian species. Explaining species differences in food selection, food-seeking and digestive strategies and their significance to nutritional needs, chapters cover a broad range of topics including digestive physiology, metabolic disorders and specific nutrients such as carbohydrates proteins and lipids, with particular attention being paid to nutritional and metabolic idiosyncrasies. It is an essential text for students of animal and veterinary sciences.
Download or read book Self Production of Supramolecular Structures written by Gail R. Fleischaker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: How did life begin on the Earth? The units of life are cells, which can be defined as bounded systems of molecules that capture energy and nutrients from the environment -- systems that expand, reproduce, and evolve over time, often into more complex systems. This book is the proceedings of a unique meeting, sponsored by NATO and held in Maratea, Italy, that brought together for the first time an international group of investigators who share an interest in how molecules self-assemble into supramolecular structures, and how those structures may have contributed to the origin of life. The book is written at a moderately technical level, appropriate for use by researchers and by students in upper-level undergraduate and graduate courses in biochemistry and molecular biology. The overall interest of its subject matter provides an excellent introduction for students who wish to understand how the foundational knowledge of chemistry and physics can be applied to one of the most fundamental questions now facing the scientific community. The editors are pioneers in defining what we mean by the living state, particularly the manner in which simple molecular systems can assume complex associations and functions, including the ability to reproduce. Each chapter of the book presents an up-to-date report of highly significant research. Two of the authors received medals from the National Academy of Science USA in 1994, and other research reported in the book has been featured in internationally recognized journals such Scientific American, Time, and Discover.
Download or read book Contemporary Treatment of Erectile Dysfunction written by Kevin T. McVary and published by Springer Science & Business Media. This book was released on 2010-12-17 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Erectile dysfunction can affect all age groups. Numerous physical and emotional risk factors may contribute to the problem. These risk factors can range from chronic diseases and medications to psychological factors. In the U.S. alone, it has been estimated that 18 to 30 million men suffer from erectile dysfunction. This number has increased significantly as awareness of the disorder has heightened. Researchers and health care professionals now have a better understanding of what causes erectile dysfunction and the effective medications and non-medication treatments used to treat the condition. Comprehensive and state-of-the-art, Contemporary Treatment of Erectile Dysfunction: A Clinical Guide synthesizes the literature and covers all aspects of treating erectile dysfunction and other related male sexual dysfunctions. This invaluable title offers all physicians, residents, and fellows -- and even medical students and other health professionals such as nurse practitioners and physician assistants – an essential reference for enhancing diagnosis and treatment of this debilitating disorder.
