Download or read book Welcome to the United States written by and published by . This book was released on 2007 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Translational Medicine written by Joy A. Cavagnaro and published by CRC Press. This book was released on 2021-11-26 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.

Download or read book Global Environmental Constitutionalism written by James R. May and published by Cambridge University Press. This book was released on 2015 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting a global trend, scores of countries have affirmed that their citizens are entitled to healthy air, water, and land and that their constitution should guarantee certain environmental rights. This book examines the increasing recognition that the environment is a proper subject for protection in constitutional texts and for vindication by constitutional courts. This phenomenon, which the authors call environmental constitutionalism, represents the confluence of constitutional law, international law, human rights, and environmental law. National apex and constitutional courts are exhibiting a growing interest in environmental rights, and as courts become more aware of what their peers are doing, this momentum is likely to increase. This book explains why such provisions came into being, how they are expressed, and the extent to which they have been, and might be, enforced judicially. It is a singular resource for evaluating the content of and hope for constitutional environmental rights.

Download or read book Sustainable procurement written by Luciana Stocco Betiol and published by Public Administration and Citizenship Program. This book was released on 2015-12-15 with total page 69 pages. Available in PDF, EPUB and Kindle. Book excerpt: “It's a fight against time." That is how the book begins, presenting a historical background of how the topic of sustainable production and consumption was included in the global agenda and reached Brazil. It is clear in the work who and what the potential actors and instruments that interact for that purpose are. In a fun way, thematic infographics show the impact from consumption and production, inspired by Life Cycle Assessment (LCA). In Chapters 2 and 3, readers will find inspiring examples of institutional procurement collected through exclusive interviews, news articles, corporate reports and scientific articles describing successful experiences in the public and private sectors, highlighting which institutions broke the resistance and became protagonists in the use of transformation potential through sustainable consumption and production. In Chapter 4, under a guidance perspective, two tools are recommended for continuously improving management of public and business procurement - the former was developed by ICLEI, for the Procura+ campaign, and the latter by the UN Global Compact. Also, propositions are presented in order to incorporate sustainability attributes in the procurement and supply management systems. Based on our experiences with consultancies and projects in partnership with governments, business platforms and academic researches, a survey was conducted with about 50 institutions, among public bodies and businesses, organizing lessons learnt and calling attention for facilitators and barriers of institutional consumption aimed at sustainability. Among the institutions we surveyed, we picked up the examples described in this work. Finally, in Chapter 5, under an integrated perspective of sectors and actors, including individual consumers, we made a critical analysis of the advancements and challenges faced in the past years, and point to guidelines for the future of the so-wanted 'inclusive green economy', considering institutional procurement as an essential tool to (re)build a global scenario that is more favorable to sustainable development.

Download or read book Corrupt Cities written by and published by World Bank Publications. This book was released on 2000 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Much of the devastation caused by the recent earthquake in Turkey was the result of widespread corruption between the construction industry and government officials. Corruption is part of everyday public life and we tend to take it for granted. However, preventing corruption helps to raise city revenues, improve service delivery, stimulate public confidence and participation, and win elections. This book is designed to help citizens and public officials diagnose, investigate and prevent various kinds of corrupt and illicit behaviour. It focuses on systematic corruption rather than the free-lance activity of a few law-breakers, and emphasises practical preventive measures rather than purely punitive or moralistic campaigns.

Download or read book Patrons Clients and Policies written by Herbert Kitschelt and published by Cambridge University Press. This book was released on 2007-03-29 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: A study of patronage politics and the persistence of clientelism across a range of countries.

Download or read book Historical Dictionary of the Dirty Wars written by David Kohut and published by Scarecrow Press. This book was released on 2010-02-18 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of Historical Dictionary of 'The Dirty Wars' focuses on the period 1954-1990 in South America, when authoritarian regimes waged war on subversion, both real and imagined. This is done through a chronology, an introductory essay, a bibliography, and over 400 cross-referenced dictionary entries on the countries; guerrilla and political movements; prominent guerrilla, human-rights, military, and political figures; local, regional, and international human-rights organizations; and artistic figures (filmmakers, novelists, and playwrights) whose works attempt to represent or resist the period of repression.

Download or read book Doing Business 2019 written by World Bank and published by World Bank Publications. This book was released on 2018-11-30 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sixteenth in a series of annual reports comparing business regulation in 190 economies, Doing Business 2019 measures aspects of regulation affecting areas of everyday business activity.

Download or read book Sediment Toxicity Assessment written by G.Allen Burton and published by CRC Press. This book was released on 2018-05-04 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sediment Toxicity Assessment provides the latest information regarding how to evaluate sediment contamination and its effects on aquatic ecosystems. It presents an integrated ecosystem approach by detailing effective assessment methods, considerations, and effects to each major component of marine and freshwater systems, including the benthos, plankton, and fish communities. The approaches emphasize defining habitat conditions (physical and chemical), toxicant bioavailability, factors influencing toxicity (lab and field), biomarkers, acute and chronic toxicity, study design, collection methods, and EPA management strategies. The book also explains how to integrate the assessments. Sediment Toxicity Assessment will be useful to to all environmental managers, environmental scientists, ecotoxicologists, environmental regulators, aquatic ecologists, environmental contractors and consultants, instructors, students, conservation commissions, and environmental activist organizations.

Download or read book European Archaeology Abroad written by S.J. van der Linde and published by Sidestone Press. This book was released on 2013-10-01 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: What are European archaeologists doing abroad? What have they been doing there for the past three to four centuries? Are they doing things differently nowadays? To address these questions, this book explores the scope, impact and ethics of European archaeological policies and practices in the Mediterranean area, the Near East, sub-Saharan Africa, Asia and Latin America. Acknowledging that international and transcultural projects have a range of different stakeholders, the first part of this book aims to identify some of the values and motivations behind different European archaeologies abroad. This is done by providing thorough historical overviews on a range of European countries, including France, Spain, Germany, Belgium, the Netherlands and Poland. But how are these values translated, through socio-political, theoretical and administrative frameworks, unto local circumstances in host countries? And how are these archaeological activities received locally? The second part of this book attempts to answer these questions through a range of historical and contemporary case studies, in Africa, in Asia, in South America, in the Near East and in Europe. The third part of the book offers several critical reflections on European values, motivations and collaboration projects, as perceived by archaeological heritage professionals based in, and/or working in Senegal, Sudan, Somaliland, Colombia, and the Near East. This collection of historical overviews, contemporary case studies and critical reflections focuses on the challenging relationships between archaeological practices and policies, including the requirements and wishes of archaeologists, of local communities and of other stakeholders in Europe and in the host countries. In addition to researchers and students, this book should be of interest to practicing archaeologists, heritage professionals and policy makers the world over, as they seek to reach better informed decisions regarding archaeological projects and international collaboration. This publication was produced in the framework of the ACE project – “Archaeology in Contemporary Europe. Professional Practices and Public Outreach”, with the support of the Culture 2007-2013 programme of the European Commission.

Download or read book Water and Sanitation Services written by Jose Esteban Castro and published by Earthscan. This book was released on 2012 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on how to provide clean water for all - one of the key Millennium Development Goals, this book integrates technical and social perspectives. A broad, international range of case studies are provided, from developed, middle income and developing countries, in Europe, Asia, Africa, and the Americas.

Download or read book Risk Habitat Megacity written by Dirk Heinrichs and published by Springer Science & Business Media. This book was released on 2011-10-09 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Megacity development and the inherent risks and opportunities for humans and the environment is a theme of growing urgency in the 21st century. Focusing on Latin America where urbanization is most advanced, this book studies the complexity of a ‘mega-urban system’ and explores interrelations between sectors and issues by providing an in-depths study of one particular city, Santiago de Chile. The book attempts to (i) focus on the emergence of risk in megacities by analyzing risk elements, (ii) evaluate the extent and severity of risks, (iii) develop strategies to cope with adverse risks, and (iv) to guide urban development by combining concepts with empirical evidence. Drawing on the work of an interdisciplinary and international consortium of academic and professional partners, the book is written for scholars in cross-cutting areas of urban, sustainability, hazard, governance and planning research as well as practitioners from local, regional and international organizations.

Download or read book Tourism and Entrepreneurship written by Jovo Ateljevic and published by Routledge. This book was released on 2017-12-04 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tourism and Entrepreneurship: International Perspectives provides an innovative, interdisciplinary approach. This book takes as its central theme the role of entrepreneurship in the context of regional, local and national tourism development. By engaging with top academics in both tourism and entrepreneurship this book delivers a cohesive, interdisciplinary examination of the most recent developments in both tourism and entrepreneurship. Several key themes are explored and articulated through the following concepts and issues: tourism, innovation and entrepreneurship; the role and nature of individual and collective entrepreneurship in different contexts; the role of tourism in responding to development opportunities created by global forces; and finally, issues associated with tourism strategies and policies. Divided into four parts, the book reflects on the most relevant areas of tourism entrepreneurship: * Understanding the conceptual basis of tourism entrepreneurship * Creative use of entrepreneurship and processes of social innovation * Tourism entrepreneurship mediating the global–local divide * Sectoral strategies and policy issues of tourism entrepreneurship Tourism and Entrepreneurship: International Perspective: * Explains the impact of tourism entrepreneurship on places and overall regional and destination development * Examines the role of the public sector in facilitating the need for sustainable tourism development * Examines the effects and implications of funding schemes and support programmes * Takes the owner, manager and entrepreneur as the starting point of analysis to explore specific issues * Allows practitioners and policy-makers to explore practical applications and best practice of theory through a diverse range of international case studies * Contributed to by an international team of leading scholars in tourism and entrepreneurship This book is a unique combination of theory, case studies and discussion highlighting the importance of entrepreneurial tourism activity for economic success. It is essential reading for students and researchers in both tourism and entrepreneurship.

Download or read book Key World Energy Statistics written by Agencia Internacional de la Energía and published by . This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Social Policies and Institutional Reform in Post COVID Cuba written by Bert Hoffmann and published by . This book was released on 2021-08-09 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: The economic crisis in the wake of the COVID pandemic is putting Cuba's socialism to a severe test. The government in Havana has added a fundamental reform of the economy, institutional structure and social policies to the agenda. This volume brings together contributions from leading international experts as well as from the island itself, analysing the economic, political and social challenges Cuba is facing today.

Download or read book Combating Corruption in Latin America written by Joseph S. Tulchin and published by . This book was released on 2000-08-17 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shihata, and Laurence Whitehead.

Download or read book World Energy Outlook 2015 written by International Energy Agency and published by . This book was released on 2015-11-25 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: The precipitous fall in oil prices, continued geopolitical instability and the ongoing global climate negotiations are witness to the dynamic nature of energy markets. In a time of so much uncertainty, understanding the implications of the shifting energy landscape for economic and environmental goals and for energy security is vital. The World Energy Outlook 2015 (WEO-2015) will present updated projections for the evolution of the global energy system to 2040, based on the latest data and market developments, as well as detailed insights on the prospects for fossil fuels, renewables, the power sector and energy efficiency and analysis on trends in CO2 emissions and fossil-fuel and renewable energy subsidies.