Download or read book Computer Simulations of Antimicrobial Peptides written by Himanshu Khandelia and published by . This book was released on 2006 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Design of Highly Active Antimicrobial Peptides Using Mathematical and Computer Modeling written by Naveen Pathak and published by . This book was released on 1994 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Antimicrobial Peptides written by Andrea Giuliani and published by Methods in Molecular Biology. This book was released on 2010-03-23 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, leading investigators present a broad, up-to-date collection of current research and experimental methods for the isolation, characterization, production, and optimization of AMPs. The book covers a rapidly expanding field of research.
Download or read book Simulations of Antimicrobial Peptides written by Allison A. Langham and published by . This book was released on 2008 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: An additional method for predicting toxicity of protegrin mutants was developed based on a quantitative structure-activity relationship using properties from short simulations of protegrins in water was developed. When tested against new sequences, the model was able to predict toxicity with high accuracy. In the methods employed, the level of detail from the simulations enabled us to hone in on specific amino acids that play important roles in activity and toxicity and will allow for the design of new peptides.
Download or read book Antimicrobial Peptides written by and published by Academic Press. This book was released on 2022-02-12 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial Peptides, Volume 663 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on Unifying the classification of antimicrobial peptides in the Antimicrobial Peptide Database, Optimizing peptide library creation for PepSAVI-MS (RP libraries, etc.), Discovery of novel Antimicrobial peptides using BioProspecting, Screening for cysteine-stabilized scaffolds for developing protelytic-resistant AMPs, Exploring synergy and its role in antimicrobial peptide biology, Colorimetric assays for the rapid and high-throughput screening of antimicrobial peptide activity against diverse bacterial pathogens, and much more. Other chapters cover Liquid chromatography-mass spectrometry-based analysis of naturally occurring neuropeptide diastereomers, Multiplexed Quantitative Neuropeptidomics via DiLeu Isobaric Tagging, In vitro evaluation of antibiotic resistance via proteomics, Molecular networking-based strategies in mass spectrometry, Development of Macrocyclic antimicrobial peptides and peptoids, and a host of other timely topics. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Methods in Enzymology serials Updated release includes the latest information on Antimicrobial Peptides
Download or read book Advances in Computational Biology written by Luis F. Castillo and published by Springer Science & Business Media. This book was released on 2013-08-04 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume compiles accepted contributions for the 2nd Edition of the Colombian Computational Biology and Bioinformatics Congress CCBCOL, after a rigorous review process in which 54 papers were accepted for publication from 119 submitted contributions. Bioinformatics and Computational Biology are areas of knowledge that have emerged due to advances that have taken place in the Biological Sciences and its integration with Information Sciences. The expansion of projects involving the study of genomes has led the way in the production of vast amounts of sequence data which needs to be organized, analyzed and stored to understand phenomena associated with living organisms related to their evolution, behavior in different ecosystems, and the development of applications that can be derived from this analysis.
Download or read book Design Characterization and Molecular Dynamics Simulations of Antimicrobial Peptides written by 蔡政育 and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Parallel Molecular Dynamics Simulations of Antimicrobial Peptides written by Svetlana Oard and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biomolecular Simulation written by Wilfred F. van Gunsteren and published by . This book was released on 1996 with total page 757 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computer Applications -- Physical Sciences and Engineering.
Download or read book Antimicrobial Peptides written by K. Ajesh and published by Academic Press. This book was released on 2022-11-23 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial Peptides: Challenges and Future Perspectives covers the latest developments about antimicrobial peptides in the scenario of drug resistance. The book is divided into 16 chapters arranged in sequence and preceded by chapters on historical developments and their role as regulatory molecules in innate defense mechanism. Emphasis is given to purification techniques and characterization suitable for interdisciplinary research. Chapters provide an inventory of various antimicrobial peptides, from a diverse array of organisms such as bacteria, fungi, insects, amphibians, plants and mammals. A section on marine ecosystem broadens readers understanding on marine based antimicrobial peptides. Additional sections provide an informative overview on peptides with antiviral properties and those targeting multi-drug resistant bacteria. Recent reports and mechanism on resistance against antimicrobial peptides are also provided, along with key insights into the challenges and future perspectives of peptide drug development. Emphasizes antimicrobial peptides targeting various human viruses and multidrug resistant bacteria Written by internationally recognized experts who provide readers with a wide and useful perspective Provides in-depth resources for undertaking a research work in antimicrobial peptides with the inclusion of chapters on purification techniques and structural details Addresses the possibility and availability of peptide antibiotics in the global drug market Serves as a complete resource from the discovery to drug development of peptide antibiotics
Download or read book Computer Aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates written by Jujjvarapu Satya Eswari and published by CRC Press. This book was released on 2019-09-24 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increase in antibiotic resistance has forced researchers to develop new drugs against microorganisms. Lipopeptides are produced as secondary metabolites by some microorganisms. Computer-aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates provides the identification of novel ligands for different antimicrobial lipopeptides. Along with identification, it also provides some of the in silico drug design processes, namely homology modelling, molecular docking, QSAR studies, drug ADMET studies and pharmacophore studies to check the ligand-lipopeptide interaction. Some lipopeptides have shown anti-cancerous properties too, and this book discusses the required templates to design new drugs using computational techniques. Key Features: Focuses on the use lipopeptides as new antimicrobial compounds Presents the basics of in silico modelling for design and development of new drug molecules, and is therefore of interest to beginners in the field Provides a step-by-step process for identification of drug molecules and testing its efficacy in silico Couples with courses on patents and intellectual property rights
Download or read book Computer Simulations of Cell penetrating Peptides written by Lauren Marie Reid and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Development of Computer designed and Naturally Occurring Antimicrobial Peptides to Target Methicillin resistant Staphylococcus Aureus MRSA Using SPOT Peptide Synthesis written by Martin Ashby and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Computational Peptide Science written by Thomas Simonson and published by . This book was released on 2022 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details current and new computational methodologies to study peptides. Chapters guide readers through antimicrobial peptides, foldability, amyloid sheet formation, membrane-active peptides, organized peptide assemblies, protein-peptide interfaces, prediction of peptide-MHC complexes, advanced free energy simulations for peptide binding, and methods for high throughput peptide or miniprotein design. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials, software, and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Computational Peptides Science: Methods and Protocols aims to provide concepts, methods, and guidelines to help both novices and experienced workers benefit from today's new opportunities and challenges.
Download or read book Antimicrobial Peptides written by Katsumi Matsuzaki and published by Springer. This book was released on 2019-04-12 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application. Divided into four major parts, the book begins with a general overview of AMPs (Part I), and subsequently discusses the various mechanisms of antimicrobial action and methods for researching them (Part 2). It then addresses a range of activities other than antimicrobial action, such as cell penetration, antisepsis, anticancer, and immunomodulatory activities (Part 3), and explores the prospects of clinical application from various standpoints such as the selective toxicity, design, and discovery of AMPs (Part 4). A huge number of AMPs have been discovered in plants, insects, and vertebrates including humans, and constitute host defense systems against invading pathogenic microorganisms. Consequently, many attempts have been made to utilize AMPs as antibiotics. AMPs could help to solve the urgent problem of drug-resistant bacteria, and are also promising with regard to sepsis and cancer therapy. Gathering a wealth of information, this book will be a bible for all those seeking to develop antibiotics, anti-sepsis, or anticancer agents based on AMPs.
Download or read book Peptide Lipid Interactions written by Sidney A. Simon and published by Academic Press. This book was released on 2002-11-13 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains a comprehensive overview of peptide-lipid interactions by leading researchers. The first part covers theoretical concepts, experimental considerations, and thermodynamics. The second part presents new results obtained through site-directed EPR, electron microscopy, NMR, isothermal calorimetry, and fluorescence quenching. The final part covers problems of biological interest, including signal transduction, membrane transport, fusion, and adhesion. Key Features * world-renowned experts * state-of-the-art experimental methods * monolayers, bilayers, biological membranes * theoretical aspects and computer simulations * rafts * synaptic transmission * membrane fusion * signal transduction
Download or read book Antimicrobial Peptides written by David A. Phoenix and published by John Wiley & Sons. This book was released on 2012-12-27 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this text, the small team of expert authors presents the field in a comprehensive and accessible manner that is well suited for students and junior researchers. The result is a highly readable and systematically structured introduction to antimicrobial peptides, their structure, biological function and mode of action. The authors point the way towards a rational design of this potentially highly effective new class of clinical antibiotics on the brink of industrial application. They do this by discussing their design principles, target membranes and structure-activity relationships. The final part of the book describes recent successes in the application of peptides as anticancer agents.
