Download or read book Computational And Mathematical Methods In Cardiovascular Physiology written by Liang Zhong and published by World Scientific. This book was released on 2019-04-26 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular diseases (CVD) including heart diseases, peripheral vascular disease and heart failure, account for one-third of deaths throughout the world. CVD risk factors include systolic blood pressure, total cholesterol, high-density lipoprotein cholesterol, and diabetic status. Clinical trials have demonstrated that when modifiable risk factors are treated and corrected, the chances of CVD occurring can be reduced. This illustrates the importance of this book's elaborate coverage of cardiovascular physiology by the application of mathematical and computational methods.This book has literally transformed Cardiovascular Physiology into a STEM discipline, involving (i) quantitative formulations of heart anatomy and physiology, (ii) technologies for imaging the heart and blood vessels, (iii) coronary stenosis hemodynamics measure by means of fractional flow reserve and intervention by grafting and stenting, (iv) fluid mechanics and computational analysis of blood flow in the heart, aorta and coronary arteries, and (v) design of heart valves, percutaneous valve stents, and ventricular assist devices.So how is this mathematically and computationally configured landscape going to impact cardiology and even cardiac surgery? We are now entering a new era of mathematical formulations of anatomy and physiology, leading to technological formulations of medical and surgical procedures towards more precise medicine and surgery. This will entail reformatting of (i) the medical MD curriculum and courses, so as to educate and train a new generation of physicians who are conversant with medical technologies for applying into clinical care, as well as (ii) structuring of MD-PhD (Computational Medicine and Surgery) Program, to train competent medical and surgical specialists in precision medical care and patient-specific surgical care.This book provides a gateway for this new emerging scenario of (i) science and engineering based medical educational curriculum, and (ii) technologically oriented medical and surgical procedures. As such, this book can be usefully employed as a textbook for courses in (i) cardiovascular physiology in both the schools of engineering and medicine of universities, as well as (ii) cardiovascular engineering in biomedical engineering departments worldwide.

Download or read book Mathematical Modelling of the Human Cardiovascular System written by Alfio Quarteroni and published by Cambridge University Press. This book was released on 2019-05-09 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addresses the mathematical and numerical modelling of the human cardiovascular system, from patient data to clinical applications.

Download or read book Mathematical Modeling of Cardiovascular Systems From Physiology to the Clinic written by Julius Guccione and published by Frontiers Media SA. This book was released on 2020-01-13 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Computational Hemodynamics Theory Modelling and Applications written by Jiyuan Tu and published by Springer. This book was released on 2015-02-24 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses geometric and mathematical models that can be used to study fluid and structural mechanics in the cardiovascular system. Where traditional research methodologies in the human cardiovascular system are challenging due to its invasive nature, several recent advances in medical imaging and computational fluid and solid mechanics modelling now provide new and exciting research opportunities. This emerging field of study is multi-disciplinary, involving numerical methods, computational science, fluid and structural mechanics, and biomedical engineering. Certainly any new student or researcher in this field may feel overwhelmed by the wide range of disciplines that need to be understood. This unique book is one of the first to bring together knowledge from multiple disciplines, providing a starting point to each of the individual disciplines involved, attempting to ease the steep learning curve. This book presents elementary knowledge on the physiology of the cardiovascular system; basic knowledge and techniques on reconstructing geometric models from medical imaging; mathematics that describe fluid and structural mechanics, and corresponding numerical/computational methods to solve its equations and problems. Many practical examples and case studies are presented to reinforce best practice guidelines for setting high quality computational models and simulations. These examples contain a large number of images for visualization, to explain cardiovascular physiological functions and disease. The reader is then exposed to some of the latest research activities through a summary of breakthrough research models, findings, and techniques. The book’s approach is aimed at students and researchers entering this field from engineering, applied mathematics, biotechnology or medicine, wishing to engage in this emerging and exciting field of computational hemodynamics modelling.

Download or read book Mathematical and Numerical Modeling of the Cardiovascular System and Applications written by Daniele Boffi and published by Springer. This book was released on 2018-11-03 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. It covers a wide range of topics, from the assimilation of clinical data to the development of mathematical and computational models, including with parameters, as well as their efficient numerical solution, and both in-vivo and in-vitro validation. It also considers applications of relevant clinical interest. This book is intended for graduate students and researchers in the field of bioengineering, applied mathematics, computer, computational and data science, and medicine wishing to become involved in the highly fascinating task of modeling the cardiovascular system.

Download or read book Introduction to Computational Cardiology written by Boris Ja. Kogan and published by Springer Science & Business Media. This book was released on 2009-12-09 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Computational Cardiology provides a comprehensive, in-depth treatment of the fundamental concepts and research challenges involved in the mathematical modeling and computer simulation of dynamical processes in the heart, under normal and pathological conditions. About this textbook: - Presents descriptions of models used in both biology and medicine for discovering the mechanisms of heart function and dysfunction on several physiological scales across different species. - Provides several examples throughout the textbook and exercises at the end which facilitate understanding of basic concepts and introduces, for implementation, treated problems to parallel supercomputers. Introduction to Computational Cardiology serves as a secondary textbook or reference book for advanced-level students in computer science, electrical engineering, biomedical engineering, and cardiac electrophysiology. It is also suitable for researchers employing mathematical modeling and computer simulations of biomedical problems.

Download or read book Applied Mathematical Models in Human Physiology written by Johnny T. Ottesen and published by SIAM. This book was released on 2004-02-01 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces mathematicians to real applications from physiology. Using mathematics to analyze physiological systems, the authors discuss models reflecting current research in cardiovascular and pulmonary physiology. In particular, they present models describing blood flow in the heart and the cardiovascular system, as well as the transport of oxygen and carbon dioxide through the respiratory system and a model for baroreceptor regulation. This is the only book available that analyzes up-to-date models of the physiological system at several levels of detail; both simple 'real-time' models that can be directly used in larger systems, and more detailed 'reference' models that show the underlying physiological mechanisms and provide parameters for and validation of simpler models. The book also covers two-dimensional modeling of the fluid dynamics in the heart and its ability to pump, and includes a discussion of modeling wave-propagation throughout the systemic arteries.

Download or read book Computational Cardiology written by Frank B. Sachse and published by Springer. This book was released on 2005-01-12 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to computer-based modeling in cardiology, by taking an educational point of view, and by summarizing knowledge from several, commonly considered delimited areas of cardiac research in a consistent way. First, the foundations and numerical techniques from mathematics are provided, with a particular focus on the finite element and finite differences methods. Then, the theory of electric fields and continuum mechanics is introduced with respect to numerical calculations in anisotropic biological media. In addition to the presentation of digital image processing techniques, the following chapters deal with particular aspects of cardiac modeling: cardiac anatomy, cardiac electro physiology, cardiac mechanics, modeling of cardiac electro mechanics. This book was written for researchers in modeling and cardiology, for clinical cardiologists, and for advanced students.

Download or read book Biomedical Engineering of Pancreatic Pulmonary and Renal Systems and Applications to Medicine written by Dhanjoo N. Ghista and published by Elsevier. This book was released on 2023-05-15 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Engineering Modeling of Pancreatic, Respiratory, and Renal Regulatory Systems, and their Medical Assessments addresses the need for biomedical engineering to provide physiological analysis of organ systems and their medical applications to help enable quantitative formulation of physiological systems and defining their functions and dysfunctions, leading to precision diagnostics of diabetes, lung diseases, and kidney failure, often in the form of non-dimensional indices. The book chapters also deal with treatment systems, namely automated insulin infusion systems, hemodialysis, and peritoneal dialysis. The book is formulated to solve many physiological, bioengineering, and medical problems. Covers foundational concepts of the emerging fields of quantitative physiology and computational medicine, developing the biomedical engineering modeling of three important organ systems: pancreas, lungs, and kidneys Provides readers with detailed understanding of novel biomedical engineering strategies in key areas, such as pancreatic system engineering, glucose-insulin regulatory system engineering, pulmonary system engineering, and renal system engineering Provides in-depth technical coverage of computational modeling techniques and applied mathematics for these important physiological systems, including differential equations and the associated MATLAB datasets for all applied diagnostic and treatment examples

Download or read book Computational Hemodynamics written by Jiyuan Tu and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses geometric and mathematical models that can be used to study fluid and structural mechanics in the cardiovascular system. Where traditional research methodologies in the human cardiovascular system are challenging due to its invasive nature, several recent advances in medical imaging and computational fluid and solid mechanics modelling now provide new and exciting research opportunities. This emerging field of study is multi-disciplinary, involving numerical methods, computational science, fluid and structural mechanics, and biomedical engineering. Certainly any new student or researcher in this field may feel overwhelmed by the wide range of disciplines that need to be understood. This unique book is one of the first to bring together knowledge from multiple disciplines, providing a starting point to each of the individual disciplines involved, attempting to ease the steep learning curve. This book presents elementary knowledge on the physiology of the cardiovascular system; basic knowledge and techniques on reconstructing geometric models from medical imaging; mathematics that describe fluid and structural mechanics, and corresponding numerical/computational methods to solve its equations and problems. Many practical examples and case studies are presented to reinforce best practice guidelines for setting high quality computational models and simulations. These examples contain a large number of images for visualization, to explain cardiovascular physiological functions and disease. The reader is then exposed to some of the latest research activities through a summary of breakthrough research models, findings, and techniques. The book?s approach is aimed at students and researchers entering this field from engineering, applied mathematics, biotechnology or medicine, wishing to engage in this emerging and exciting field of computational hemodynamics modelling.

Download or read book Computational Methods in Cardiac Electrophysiology written by Matthijs Cluitmans and published by Frontiers Media SA. This book was released on 2023-07-06 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mathematical and Computational Methods in Physiology written by L. Fedina and published by Elsevier. This book was released on 2013-10-22 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical and Computational Methods in Physiology discusses the importance of quantitative description of physiological phenomena and for quantitative comparison of experimental data. An article explains the homeostasis of the body with a focus on the controlling aspects. This section evaluates the concepts of modern physiology and biocybernetics. The canal-ocular reflex and the otolith-ocular reflex in man stimulates eye rotations compensatory for head angular and linear displacements. The book enumerates some modelling and simulation to observe the visual-vestibular interaction during angular and linear body acceleration. A section on the determination of cardiovascular control is given. The text reviews the mathematical models of the biological age of the rat. A numerical simulation of water transport in epithelial junctions is explained comprehensively. A chapter analyzing the computer simulation of drug-receptor interaction is presented. The book will provide useful information to zoologists, doctors, ophthalmologists, students and researchers in the field of medicine.

Download or read book Cardiovascular Mathematics written by Luca Formaggia and published by Springer Science & Business Media. This book was released on 2010-06-27 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical models and numerical simulations can aid the understanding of physiological and pathological processes. This book offers a mathematically sound and up-to-date foundation to the training of researchers and serves as a useful reference for the development of mathematical models and numerical simulation codes.

Download or read book Mathematical Cardiac Electrophysiology written by Piero Colli Franzone and published by Springer. This book was released on 2014-10-30 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the main mathematical and numerical models in computational electrocardiology, ranging from microscopic membrane models of cardiac ionic channels to macroscopic bidomain, monodomain, eikonal models and cardiac source representations. These advanced multiscale and nonlinear models describe the cardiac bioelectrical activity from the cell level to the body surface and are employed in both the direct and inverse problems of electrocardiology. The book also covers advanced numerical techniques needed to efficiently carry out large-scale cardiac simulations, including time and space discretizations, decoupling and operator splitting techniques, parallel finite element solvers. These techniques are employed in 3D cardiac simulations illustrating the excitation mechanisms, the anisotropic effects on excitation and repolarization wavefronts, the morphology of electrograms in normal and pathological tissue and some reentry phenomena. The overall aim of the book is to present rigorously the mathematical and numerical foundations of computational electrocardiology, illustrating the current research developments in this fast-growing field lying at the intersection of mathematical physiology, bioengineering and computational biomedicine. This book is addressed to graduate student and researchers in the field of applied mathematics, scientific computing, bioengineering, electrophysiology and cardiology.

Download or read book Computational Biology of the Heart written by Alexander V. Panfilov and published by Wiley-Blackwell. This book was released on 1997-03-28 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modelling the genesis and propagation of electrical activity in the heart in quantitative terms is one of the most important recent applications of mathematical modelling in biology. The main research direction, and the most important for biological and medical applications, is the development of realistic models of electrical activity in cardiac tissue and the whole mammalian heart. Recent progress in nonlinear dynamics, advances in computer technology and experiments on cardiac tissue have made feasible the construction of such models. Computational Biology of the Heart is the first book to provide a comprehensive survey of recent research together with a systematic overview of the subject. The contributions, all written by experts in the different areas of the subject, cover all main aspects of whole heart modelling: from excitation in single cells, to two and three dimensional models of cardiac tissue and the whole heart. Various computational models and techniques are described and then applied to reconstruct and visualise modelled activity in both normal and pathological heart tissues. The models are nonlinear and use techniques of ordinary differential equations, partial differential equations and eikonal equations. The book also provides a review of modelling cardiac contraction, mapping electrical activity from electrocardiograms, and recent experimental observations of wave propagation in the whole heart. Graduate students and researchers in such areas as applied mathematical biology, clinical physiology and cardiology will find this book to be an invaluable resource for their work.

Download or read book Assessing Complexity in Physiological Systems through Biomedical Signals Analysis written by Paolo Castiglioni and published by MDPI. This book was released on 2021-03-02 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complexity is a ubiquitous phenomenon in physiology that allows living systems to adapt to external perturbations. Fractal structures, self-organization, nonlinearity, interactions at different scales, and interconnections among systems through anatomical and functional networks, may originate complexity. Biomedical signals from physiological systems may carry information about the system complexity useful to identify physiological states, monitor health, and predict pathological events. Therefore, complexity analysis of biomedical signals is a rapidly evolving field aimed at extracting information on the physiological systems. This book consists of 16 contributions from authors with a strong scientific background in biomedical signals analysis. It includes reviews on the state-of-the-art of complexity studies in specific medical applications, new methods to improve complexity quantifiers, and novel complexity analyses in physiological or clinical scenarios. It presents a wide spectrum of methods investigating the entropic properties, multifractal structure, self-organized criticality, and information dynamics of biomedical signals touching upon three physiological areas: the cardiovascular system, the central nervous system, the heart-brain interactions. The book is aimed at experienced researchers in signal analysis and presents the latest trends in the complexity methods in physiology and medicine with the hope of inspiring future works advancing this fascinating area of research.

Download or read book Computational Cardiovascular Mechanics written by Julius M. Guccione and published by Springer Science & Business Media. This book was released on 2010-01-08 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Cardiovascular Mechanics provides a cohesive guide to creating mathematical models for the mechanics of diseased hearts to simulate the effects of current treatments for heart failure. Clearly organized in a two part structure, this volume discusses various areas of computational modeling of cardiovascular mechanics (finite element modeling of ventricular mechanics, fluid dynamics) in addition to a description an analysis of the current applications used (solid FE modeling, CFD). Edited by experts in the field, researchers involved with biomedical and mechanical engineering will find Computational Cardiovascular Mechanics a valuable reference.