Download or read book Comprehensive Two dimensional Chromatographic Techniques for Ultra trace Quantitative Analysis of Chlorinated Dioxins in South Africa written by Betty-Jayne de Vos and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) are toxic environmental pollutants formed as by-products of industrial and thermal processes. They are chlorinated compounds that have similar structures and chemical properties that were included in the original United Nations Environment Programme’s ‘dirty dozen’ and now form part of the Stockholm Convention (SC) on Persistent Organic Pollutants (POPs). As a signatory to the Stockholm Convention, South Africa has the obligation to undertake appropriate research, monitoring, and cooperation pertaining to POPs, and more particularly, PCDD/Fs. Currently there is no established PCDD/F laboratory in South Africa capable of these demanding measurements and alternative approaches must be considered that are more affordable, more robust and more user friendly for a developing economy. PCDD/Fs are highly toxic, causing a myriad of negative human health effects such as chloracne, carcinogenicity, hepatotoxicity, teratogenicity, endocrine disruption and alterations in neural development. The toxicity of PCDD/Fs is mediated through the aryl hydrocarbon receptor (AhR). PCDD/Fs bind to the AhR and elicit an AhR-mediated biochemical and toxic response. The in-depth information available on the mechanism of toxicity also allows for PCDD/Fs to be analysed using the AhR receptor mediated response in genetically modified cell lines. This led to the development of a bio-analytical screening technique using in vitro H4IIE-luc reporter gene bio-assay for AhR active compounds for the initial screening of PCDD/Fs in soil and sediment. The intension in this study was to develop an integrated approach to the analysis of PCDD/Fs in the South African environment, considering the associated cost as well as the available instrumentation, expertise and relevance within a developing economy. Historically, the quantitative confirmatory analysis of these compounds has been achieved by targeted analysis using gas chromatography coupled with high-resolution magnetic sector mass spectrometry instruments (GC-HRMS), the accepted benchmark technology used for determining the level of trace organic environmental contaminants such as PCDD/Fs. However, these methods are time consuming and expensive. Advances in technology have led to comprehensive two-dimensional gas chromatography - time-of-flight mass spectrometry (GC×GC-TOFMS) methodology that can be used for the analysis of PCDD/Fs in samples with different matrices. This approach is well suited for application in developing economies where access to GC-HRMS and highly skilled personnel is limited. This thesis describes the bio-analytical technique and the method development and analysis of the seventeen toxic PCDD/F congeners using GC×GC-TOFMS methodology. The technique provides the selectivity (added peak capacity of GC×GC) and the sensitivity (focusing effect of the modulator) needed to meet the requirements as mandated for analysis in US EPA Method 1613B. Extracted samples analysed on a GC-HRMS instrument, were re-analyzed using the low-resolution GC×GC-TOFMS instrument and the results confirmed using a high resolution TOF mass spectrometer (HRT). The quantitative results obtained compare well with those obtained using GC-HRMS. Because GC×GC-TOFMS is not a target compound analytical technique (as is GC-HRMS), it is possible to obtain information on numerous other classes of organic pollutants present in the samples in one analytical run, although this information can be sample clean-up dependant. Preliminary validation of the GC×GC-TOFMS method is investigated using a certified reference material and real South African soil samples. The South African soil samples studied showed extremely high levels of PAHs, aliphatic hydrocarbons and sulphur. The organic content and matrix interference of South African soil samples (and the NIST standard reference material sediment; SRM 1944) provided significant challenges for the validation study. This study has shown that GC×GC-TOFMS provides a quick, convenient screen for numerous pollutant classes which may be present in environmental samples. Retrospective data mining of archived data (extraction dependant) is possible and has provided key information on other chlorinated and brominated contaminants present in South African waste, soil and sediment samples. NMISA now has a viable GC×GC-TOFMS dioxin analytical method for low level (ultra-trace) quantitative screening of chlorinated compounds that can be offered to South African analytical laboratories for routine dioxin analysis. The work is relevant scientifically and is a definitive contribution to the growing compilation of GC×GC methodology, providing efficient methods for this demanding environmental application.
Download or read book Recent Advances in Ultratrace Analysis of Dioxins and Related Halogenated Hydrocarbons written by B. K. Afghan and published by . This book was released on 1986 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Comprehensive Two dimensional Gas Chromatography with Selective Detection for the Trace Analysis of Organohalogenated Contaminants written by Peter Korytár and published by . This book was released on 2006 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Comprehensive Two dimensional Liquid Chromatography and High Throughput Effect directed Analysis in Environmental Research written by and published by . This book was released on 2016 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Comprehensive Environmental Mass Spectrometry written by Albert Lebedev and published by ILM Publications. This book was released on 2012 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In full colour throughout, this book describes the power of mass spectrometry in resolving environmental issues, demonstrating how real-world complex problems can be solved in a simple and elegant way."--Worldcat.
Download or read book Some Chemicals Present in Industrial and Consumer Products Food and Drinking water written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by IARC Monographs on the Evaluat. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.
Download or read book Handbook of Solid Phase Microextraction written by Janusz Pawliszyn and published by Elsevier. This book was released on 2011-12-01 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: The relatively new technique of solid phase microextraction (SPME) is an important tool to prepare samples both in the lab and on-site. SPME is a "green" technology because it eliminates organic solvents from analytical laboratory and can be used in environmental, food and fragrance, and forensic and drug analysis. This handbook offers a thorough background of the theory and practical implementation of SPME. SPME protocols are presented outlining each stage of the method and providing useful tips and potential pitfalls. In addition, devices and fiber coatings, automated SPME systems, SPME method development, and In Vivo applications are discussed. This handbook is essential for its discussion of the latest SPME developments as well as its in depth information on the history, theory, and practical application of the method. Practical application of Solid Phase Microextraction methods including detailed steps Provides history of extraction methods to better understand the process Suitable for all levels, from beginning student to experienced practitioner
Download or read book Applications of Gas Chromatography written by Adrianna Coty and published by . This book was released on 2016-04-01 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gas chromatography is a term used to describe the group of analytical separation techniques used to analyze volatile substances in the gas phase. In gas chromatography, the components of a sample are dissolved in a solvent and vaporized in order to separate the analyses by distributing the sample between two phases: a stationary phase and a mobile phase. The mobile phase is a chemically inert gas that serves to carry the molecules of the analyze through the heated column. Gas chromatography is one of the sole forms of chromatography that does not utilize the mobile phase for interacting with the analyze. The stationary phase is either a solid adsorbent, termed gas-solid chromatography (GSC), or a liquid on an inert support, termed gas-liquid chromatography (GLC). Helium remains the most commonly used carrier gas in about 90% of instruments although hydrogen is preferred for improved separations. This inert gas goes through a glass column packed with silica that is coated with a liquid. Materials that are less soluble in the liquid will increase the result faster than the material with greater solubility. The purpose of this book entitled Applications of Gas Chromatography is to provide a better understanding on its separation and measurement techniques and its application. Since chromatography techniques are separating and analyzing methods, this book will help other researchers and young scientists to choose a suitable chromatography technique. Furthermore, this book illustrates the newest challenges in this area. This valuable book aims to provide a connection between various chromatography techniques and different processes.
Download or read book TECHNEAU written by Christian Kazner and published by IWA Publishing. This book was released on 2009-06-14 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: The best papers from the three-day conference on Safe Drinking Water from Source to Tap June 2009 in Maastricht are published in this book covering the themes of challenges of the water sector and adaptive strategies, treatment, distribution, risk assessment and risk management, sensors and monitoring, small scale systems, simulation, alternative water supply & sources, consumer involvement, and future drinking water. Worldwide, the water supply sector is facing tremendous challenges. Every new emerging contaminants and pathogens and aging infrastructures that are vulnerable for deliberate contamination pose a threat to the quality of water supplies. Shortage of good quality and readily treatable resources is increasing due to global warming, urbanisation and pollution from agriculture and industry. Regulators and consumers are becoming more demanding. Techneau - the largest European project on drinking water - addresses these challenges by developing adaptive supply system options and new and improved treatment and monitoring technologies. Future system options to be studied are flexible, small scale and multi-source supplies, utilising non conventional resources like brackish ground water, treated wastewater and urban groundwater.
Download or read book Toxicological Profile for Pyrethrins and Pyrethroids written by and published by . This book was released on 2003 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Water Quality Assessments written by Deborah V Chapman and published by CRC Press. This book was released on 1996-08-22 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guidebook, now thoroughly updated and revised in its second edition, gives comprehensive advice on the designing and setting up of monitoring programmes for the purpose of providing valid data for water quality assessments in all types of freshwater bodies. It is clearly and concisely written in order to provide the essential information for all agencies and individuals responsible for the water quality.
Download or read book Environmental Forensics for Persistent Organic Pollutants written by Gwen O'Sullivan and published by Newnes. This book was released on 2013-11-20 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Forensics for Persistent Organic Pollutants represents the state-of-the-art in environmental forensics in relation to persistent organic pollutants (POPs). The book is a complete reference for practitioners and students, covering a range of topics from new analytical techniques to regulatory and legal status in the global community. Through case studies from leading international experts, real-world issues — including the allocation of responsibility for release into the environment — are resolved through the application of advanced analytical and scientific techniques. This book introduces and assesses the development of new techniques and technologies to trace the source and fate of newly emerging and classic POPs (perfluoroalkyl substances, brominated flame retardants, organochlorine pesticides, perfluorinated chemicals, polycyclic aromatic hydrocarbons, and polychlorinated biphenyls) in environmental media, including atmospheric, marine, freshwater, and urban environments. Real-world case studies show the application of advanced analytical and scientific techniques Discussion of GC*GC provides an introduction and assessment of a novel technique from leaders in the field Introduces the development of new analytical techniques (such as 2-D GC*HC and LC*LC) to trace the source and fate Raises awareness about the health and environmental impact of persistent organic pollutants (POPs) Outlines the development of international measures to control POPs so that chemists can understand the legal issues
Download or read book The Chemical Scythe written by Alastair Hay and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Chemical Scythe is the first book in a projected series to be published by Plenum Press in association with the International Disaster Institute. The aim of the series, Disaster Research in Practice, is to provide scientific and readable accounts on the most urgent areas of disaster research. It is fitting, therefore, that Dr. Hay's investigation into the nature and effects of dioxins heralds the new series. The problem of chemical hazards is one that we will have to learn to live with in future decades. Dr. Hay's book is an authoritative account of the chemistry and proven and potential effects of dioxins, and of the impli cations for safety planning. He concludes with a cautious, yet optimistic note-that indeed we can learn to live with such hazards, providing that we are prepared to understand and plan for the unexpected. The accident at Seveso in 1976 alerted the world to an imperfectly un derstood but immensely alarming environmental hazard. Public debate and argument as to the implications of dioxins and, indeed, the use of herbicides as aggressive weapons in Vietnam, rage on. And yet it is only through the painstaking research exemplified in this book that it will eventually be pos sible to promote the vital accountability on the part of industrialists and governments.
Download or read book Advanced Oxidation Processes for Water and Wastewater Treatment written by Simon Parsons and published by IWA Publishing. This book was released on 2004-03-01 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: The suitability of Advanced Oxidation Processes (AOPs) for pollutant degradation was recognised in the early 1970s and much research and development work has been undertaken to commercialise some of these processes. AOPs have shown great potential in treating pollutants at both low and high concentrations and have found applications as diverse as ground water treatment, municipal wastewater sludge destruction and VOCs control. Advanced Oxidation Processes for Water and Wastewater Treatment is an overview of the advanced oxidation processes currently used or proposed for the remediation of water, wastewater, odours and sludge. The book contains two opening chapters which present introductions to advanced oxidation processes and a background to UV photolysis, seven chapters focusing on individual advanced oxidation processes and, finally, three chapters concentrating on selected applications of advanced oxidation processes. Advanced Oxidation Processes for Water and Wastewater Treatment will be invaluable to readers interested in water and wastewater treatment processes, including professionals and suppliers, as well as students and academics studying in this area. Dr Simon Parsons is a Senior Lecturer in Water Sciences at Cranfield University with ten years' experience of industrial and academic research and development.
Download or read book Advanced Gas Chromatography written by Mustafa Ali Mohd and published by BoD – Books on Demand. This book was released on 2012-03-21 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in agricultural, biomedical and industrial applications' is a compilation of recent advances and developments in gas chromatography and its applications. The chapters cover various aspects of applications ranging from basic biological, biomedical applications to industrial applications. Book chapters analyze new developments in chromatographic columns, microextraction techniques, derivatisation techniques and pyrolysis techniques. The book also includes several aspects of basic chromatography techniques and is suitable for both young and advanced chromatographers. It includes some new developments in chromatography such as multidimensional chromatography, inverse chromatography and some discussions on two-dimensional chromatography. The topics covered include analysis of volatiles, toxicants, indoor air, petroleum hydrocarbons, organometallic compounds and natural products. The chapters were written by experts from various fields and clearly assisted by simple diagrams and tables. This book is highly recommended for chemists as well as non-chemists working in gas chromatography.
Download or read book Treatment of Micropollutants in Water and Wastewater written by Jurate Virkutyte and published by IWA Publishing. This book was released on 2010-08-14 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last few years there has been a growing concern over the increasing concentration of micropollutants originating from a great variety of sources including pharmaceutical, chemical engineering and personal care product industries in rivers, lakes, soil and groundwater. As most of the micropollutants are polar and persistent compounds, they are only partially or not at all removed from wastewater and thus can enter the environment posing a great risk to the biota. It is hypothesized that wastewater is one of the most important point sources for micropollutants. Treatment of Micropollutants in Water and Wastewater gives a comprehensive overview of modern analytical methods and will summarize novel single and hybrid methods to remove continuously emerging contaminants - micropollutants from the aqueous phase. New trends (e.g. sensor technology, nanotechnology and hybrid treatment technologies) are described in detail. The book is very timely because the new techniques are still in the development phase and have to be realized not only in the laboratory but also on a larger scale. The content of the book is divided into chapters that present current descriptive and analytical methods that are available to detect and measure micropollutants together with detailed information on various chemical, biological and physicochemical methods that have evolved over the last few decades. Treatment of Micropollutants in Water and Wastewater will also enable readers to make well informed choices through providing an understanding of why and how micropollutants must be removed from water sources, and what are the most appropriate and available techniques for providing a cost and technologically effective and sustainable solutions for reaching the goal of micropollutant-free water and wastewater. The book will be suitable for water and wastewater professionals as well for students and researchers in civil engineering, environmental engineering and process engineering fields.
Download or read book Methods and Techniques for Cleaning up Contaminated Sites written by Michael D. Annable and published by Springer Science & Business Media. This book was released on 2008-01-29 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication comprises the presentations made at the NATO Advanced Research Workshop held in Sinaia, Romania 9 – 11 October, 2006. The contributions represent a unique cross section of issues and challenges related to contaminated site management. These range from low cost solutions to petroleum contaminated sites to advances in biological treatment methods. The publication is meant to foster links between groups facing challenges cleaning up contaminated sites.
