Download or read book Comprehensive Insights into Type 1 Diabetes Mellitus From Molecular Mechanisms to Holistic Management written by Dr. Spineanu Eugenia and published by Dr. Spineanu Eugenia. This book was released on 2024-03-03 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Comprehensive Insights into Type 1 Diabetes Mellitus: From Molecular Mechanisms to Holistic Management" is an exhaustive exploration of Type 1 Diabetes Mellitus (T1DM), a chronic condition affecting millions worldwide. This treatise delves deep into the intricate biochemistry, genetics, and physiology underpinning T1DM, offering readers a detailed understanding of the disease's onset and progression. Beginning with a historical overview, the work traces the evolution of our understanding of diabetes, leading to the latest research and findings. The treatise meticulously examines the pancreatic structure and the pivotal role of insulin and glucagon, elucidating their complex interplay in glucose regulation. It further delves into the cellular mechanisms of glucose uptake and the metabolic pathways of glycolysis and gluconeogenesis. A significant portion is dedicated to the autoimmune aspects of T1DM, discussing the genetic predispositions, environmental triggers, and the autoimmune destruction of pancreatic beta cells. Beyond the cellular and molecular dimensions, this work adopts a holistic approach to T1DM management. It encompasses nutritional therapies, herbal remedies, and the significance of mind-body medicine. Cutting-edge technological advancements in glucose monitoring and insulin delivery systems are thoroughly explored, offering a glimpse into the future of T1DM management. The treatise also underscores the psychological and social challenges faced by individuals with T1DM, emphasizing the importance of mental health, coping mechanisms, and robust support systems. With dedicated sections on pediatric T1DM, global health perspectives, and the latest in diabetes research, this treatise serves as an invaluable resource for medical professionals, researchers, patients, and anyone seeking an in-depth understanding of T1DM. Its comprehensive nature, combined with a clear and accessible writing style, ensures it stands out as a seminal work in the field of endocrinology.
Download or read book Rongo Rkau written by Donna Kerridge and published by . This book was released on 2018-08 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: Donna Kerridge compiled this 68pg workbook for her rongoa Maori students. However due to public requests for copies of the workbook she has decided to make it available to a wider audience. The workbook should be read in conjunction with the beautiful book written by Rob McGowan - Rongoa Maori, a practical guide to traditional Maori medicine
Download or read book Computational Epigenetics and Diseases written by and published by Academic Press. This book was released on 2019-02-06 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Epigenetics and Diseases, written by leading scientists in this evolving field, provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases. In particular, the major computational tools, databases, and strategies for computational epigenetics analysis, for example, DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA, are summarized, in the context of human diseases. This book discusses bioinformatics methods for epigenetic analysis specifically applied to human conditions such as aging, atherosclerosis, diabetes mellitus, schizophrenia, bipolar disorder, Alzheimer disease, Parkinson disease, liver and autoimmune disorders, and reproductive and respiratory diseases. Additionally, different organ cancers, such as breast, lung, and colon, are discussed. This book is a valuable source for graduate students and researchers in genetics and bioinformatics, and several biomedical field members interested in applying computational epigenetics in their research. Provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases Summarizes the major computational tools, databases, and strategies for computational epigenetics analysis, such as DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA Covers the major milestones and future directions of computational epigenetics in various kinds of human diseases such as aging, atherosclerosis, diabetes, heart disease, neurological disorders, cancers, blood disorders, liver diseases, reproductive diseases, respiratory diseases, autoimmune diseases, human imprinting disorders, and infectious diseases
Download or read book Molecular Epidemiology written by Paul A. Schulte and published by Academic Press. This book was released on 2012-12-02 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.
Download or read book Obesity and Lipotoxicity written by Ayse Basak Engin and published by Springer. This book was released on 2017-06-05 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the resultant health consequences and considerable increase in prevalence, obesity has become a major worldwide health problem. “Obesity and Lipotoxicity” is a comprehensive review of the recent researches to provide a better understanding of the lipotoxicity-related mechanisms of obesity and the potential for the development of new treatment strategies. This book overviews the biochemical pathways leading to obesity-related metabolic disorders that occur subsequent to lipotoxicity. Chapters examine the deleterious effects of nutrient excess at molecular level including the cellular and molecular aspects of breast cancer, resistance to leptin, insulin, adiponectin, and interconnection between the circadian clock and metabolic pathways during high-fat feeding. “Lipotoxicity and Obesity” will be a useful resource for clinicians and basic science researchers, such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, cardiologists, as well as students who are thought in this field.
Download or read book Pancreas and Islet Transplantation written by Nadey S. Hakim and published by . This book was released on 2002 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes Mellitus is the principle cause of kidney failure and blindness in adults and leads to more cases of amputation and impotence than any other disease. It is one of the most common chronic diseases in childhood. The aims of pancreas or islet transplantation are to improve the quality of life of patients with insulin dependent diabetes mellitus and to ameliorate secondary complications. This book provides a comprehensive and international review of the recent advances in pancreas and islet transplantation. It covers surgical techniques, issues surrounding organ preservation, immunosuppression and the control of other complications, all of which contribute to the potential for such transplantations to evolve as the treatment of choice for insulin dependent diabetes. The editors have compiled a strong and international team of contribution authors. This book is essential reading for transplant surgeons and all those involved in researching or treating diabetes mellitus.
Download or read book Fast Facts Type 1 Diabetes in Adults written by R. Zaidi and published by Karger Medical and Scientific Publishers. This book was released on 2021-10-07 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Fast Facts: Type 1 Diabetes in Adults' provides a practical overview of this chronic autoimmune condition. Written by and for health professionals working in primary care, this colourful and accessible handbook highlights important practice points that cover: • the identification and management of adults with type 1 diabetes • the prevention and treatment of complications • advances in technology and future treatments An indispensable read for anyone wanting to get up to speed with best practice in primary care. Table of Contents: • Overview • Diagnosis • Management • Hypoglycemia • Education • Special circumstances • Complications • Living with the condition • Technology • Future treatments
Download or read book Mitochondria in Obesity and Type 2 Diabetes written by Beatrice Morio and published by Academic Press. This book was released on 2019-04-26 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key concepts on topics such as the role of mitochondria in adipose tissue, cancer, cardiovascular comorbidities, skeletal muscle, the liver, kidney, and more. This book is a must-have reference for students and educational teams in biology, physiology and medicine, and researchers. Synthesizes actual knowledge on mitochondrial function Provides an integrated vision of each tissue in the etiology of obesity and type 2 diabetes Identifies the interactive networks that involve alteration in mitochondrial mass and function in disease progression Highlights the role played by mitochondria in the prevention and treatment of obesity and type 2 diabetes
Download or read book Genes and Evolution written by and published by Academic Press. This book was released on 2016-06-06 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genes and Evolution, the latest volume in the Current Topics in Developmental Biology series, covers genes and evolution, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as genes and plant domestication, gene networks, phenotypic loss in vertebrates, reproducible evolutionary changes, and epithelial tissue. Covers the area of genes and evolution Contains invaluable contributions from an international board of authors Provides a comprehensive set of reviews covering such topics as genes and plant domestication, gene networks, phenotypic loss in vertebrates, reproducible evolutionary changes and epithelial tissue
Download or read book Network Pharmacology written by Shao Li and published by Springer Nature. This book was released on 2021-09-29 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1996 with total page 1548 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Practical Guide to Diabetes Mellitus written by Nihal Thomas and published by JAYPEE BROTHERS PUBLISHERS. This book was released on 2012-12-15 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Sixth Edition of A Practical Guide to Diabetes Mellitus offers a unique combination of rigorous pathophysiology with very practical approaches to diabetes prevention and control. This outstanding textbook will equip a cadre of doctors and other health care professionals to deliver high quality care to vulnerable populations around India and far beyond. Based on research as well as clinical practice, the text describes diabetes in relation to physiology, ocular, cardiovascular, neuropathy, pregnancy, emergencies, childhood diabetes, etc. Each chapter beings with a brief outline of the disease concerned followed by introduction, definition/terminology, classification, treatment, conclusion and ending with set of question for self-assessment. Covers step wise images describes insulin administration in subcutaneous and using pen devices in the chapter: Insulin therapy: practical aspects. Feet, Footcare and Neuroarthropathy chapter deals with etiology and pathophysiology and is divided into three parts: Ulceration, Neuroarthropathy and Peripheral Artery Occlusive(PAD) diseases. Infection in diabetes chapter focuses on infection related to head and neck, genitourinary, skin and soft tissue, pulmonology and abdominal. Recent advances includes application of new drugs like Taspoglutide, Albiglutide, Lixisenatide, Newer DPP-IV inhibitors, along with new insulin receptor activators, PPAR agonists, new hepatic targets for glycemic control in diabetes. This book contains more than 300 coloured images and illustrations, 40 clinical cases, 50 questions for quick revision along with answers to the self-assessments question given at the end of book."
Download or read book Cellular Transplantation written by Craig Halberstadt and published by Elsevier. This book was released on 2011-10-10 with total page 699 pages. Available in PDF, EPUB and Kindle. Book excerpt: There have been tremendous strides in cellular transplantation in recent years, leading to accepted practice for the treatment of certain diseases, and use for many others in trial phases. The long history of cellular transplantation, or the transfer of cells from one organism or region of the body to another, has been revolutionized by advances in stem cell research, as well as developments in gene therapy. Cellular Transplants: From Lab to Clinic provides a thorough foundation of the basic science underpinning this exciting field, expert overviews of the state-of-the-art, and detailed description of clinical success stories to date, as well as insights into the road ahead. As highlighted by this timely and authoritative survey, scale-up technologies and whole organ transplantation are among the hurdles representing the next frontier. The contents are organized into four main sections, with the first covering basic biology, including transplant immunology, the use of immunosuppressive drugs, stem cell biology, and the development of donor animals for transplantation. The next part looks at peripheral and reconstructive applications, followed by a section devoted to transplantation for diseases of the central nervous system. The last part presents efforts to address the key challenges ahead, such as identifying novel transplantable cells and integrating biomaterials and nanotechnology with cell matrices. Provides detailed description of clinical trials in cell transplantation Review of current therapeutic approaches Coverage of the broad range of diseases addressed by cell therapeutics Discussion of stem cell biology and its role in transplantation
Download or read book The Diabetes Textbook written by Joel Rodriguez-Saldana and published by Springer. This book was released on 2019-06-27 with total page 1040 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes has become a worldwide health problem, the global estimated prevalence approaches ten percent and the burden of this disease in terms of morbidity and mortality is unprecedented. The advances acquired through the knowledge of the mechanisms of the disease and the variety of therapeutic approaches contrast with the inability of private and public health systems in underdeveloped and even developed countries to achieve the goals of treatment. This paradox has been described in many sources: the surge of scientific advances contrast with an unprecedented amount of human suffering. Thus, a patient centered and an evidence based approach with the capacity to produce measurable clinical and economic outcomes is required. The purpose of this textbook is multiple: to offer a comprehensive resource covering all aspects of outpatient management; to address diabetes as a health problem from an epidemiological, economic and clinical perspective; to discuss the role of social determinants of health on the worldwide increase in diabetes; to highlight the challenges and obstacles in providing adequate care; and to outline a multidisciplinary approach to management in which medical visits retain their importance as part of a team comprising the patient, his or her family and a multidisciplinary group of health professionals who are able to move beyond the traditional approach of diabetes as a disease and greatly improve outcomes.
Download or read book Obesity and Diabetes written by Christos S. Mantzoros and published by Springer Science & Business Media. This book was released on 2007-11-16 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: International experts from world-renowned medical schools comprehensively review for practicing clinicians and scientists alike the latest understanding of the epidemiology, causation, and consequences of diabetes and obesity. The authors discuss in detail their diagnosis, clinical manifestations, complications, and best practices for diagnosis and treatment. They also review the history and epidemiology of these conditions, explain their genetics and pathophysiology, and illuminate their known mechanisms and interactions. State-of-the-art survey-chapters critique current approaches (lifestyle and pharmacological) to the treatment of these conditions.
Download or read book Nutrigenomics and Nutrigenetics in Functional Foods and Personalized Nutrition written by Lynnette R. Ferguson and published by CRC Press. This book was released on 2016-04-19 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: While functional foods have become a reasonably well-established concept, personalized nutrition is still treated with skepticism by many. The recognition that people would have different nutrient requirements, or perceive foods in different ways, raises several concerns-some real, some not so real. Nutrigenomics and Nutrigenetics in Functional Foo
Download or read book Relieving Pain in America written by Institute of Medicine and published by National Academies Press. This book was released on 2011-10-26 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic pain costs the nation up to $635 billion each year in medical treatment and lost productivity. The 2010 Patient Protection and Affordable Care Act required the Department of Health and Human Services (HHS) to enlist the Institute of Medicine (IOM) in examining pain as a public health problem. In this report, the IOM offers a blueprint for action in transforming prevention, care, education, and research, with the goal of providing relief for people with pain in America. To reach the vast multitude of people with various types of pain, the nation must adopt a population-level prevention and management strategy. The IOM recommends that HHS develop a comprehensive plan with specific goals, actions, and timeframes. Better data are needed to help shape efforts, especially on the groups of people currently underdiagnosed and undertreated, and the IOM encourages federal and state agencies and private organizations to accelerate the collection of data on pain incidence, prevalence, and treatments. Because pain varies from patient to patient, healthcare providers should increasingly aim at tailoring pain care to each person's experience, and self-management of pain should be promoted. In addition, because there are major gaps in knowledge about pain across health care and society alike, the IOM recommends that federal agencies and other stakeholders redesign education programs to bridge these gaps. Pain is a major driver for visits to physicians, a major reason for taking medications, a major cause of disability, and a key factor in quality of life and productivity. Given the burden of pain in human lives, dollars, and social consequences, relieving pain should be a national priority.
