Download or read book Transplantation of Composite Tissue Allografts written by Charles W. Hewitt and published by Springer Science & Business Media. This book was released on 2007-12-20 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brilliant synthesis summarizes all of the recent accomplishments – as well as the ongoing research – in the field of composite tissue transplantation. It includes sections on hand transplantation and vascularized bone marrow transplantation. The volume focuses on immunology and the biotechnology/bioengineering aspects of transplantation surgery, as those two areas have demonstrated the most growth within the last five years in terms of current research.
Download or read book Composite Tissue Allograft written by Hakim Nadey S and published by World Scientific. This book was released on 2006-05-05 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first textbook of its kind dealing with composite tissue allograft and allograft transplantation, provides an excellent overview on the subject. It provides a clear description of the current status of the transplant of every composite tissue allograft already performed and others which are still at the basic experimental level.The editors of the book, who also contribute chapters in their expertise, are world renowned surgeons. This book opens with an introductory chapter on the history of this type of transplantation and then details the clinical experience in each graft such as hand, larynx, face, uterus and the related histopathology, immunosuppression and immunomodulation.A multidisciplinary and comprehensive presentation of the various aspects of this new area of transplantation will allow the reader to understand the complexity and the challenges of composite tissue transplantation. A number of important topics are analyzed and discussed in detail, such as the ethical, medicolegal, psychological and immunological implications. New rehabilitation techniques and strategies, together with innovative tools for the functional evaluation of the transplanted parts, are highlighted. A section on the experimental work underlines what lies ahead of us./a
Download or read book Composite Tissue Allografts written by Jean-Michel Dubernard and published by MIT Press. This book was released on 2002 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transplanting hands -- a model of composite tissue grafting -- began in Lyons in November 1998 with the transplant of one hand and then, in January 2000, of two, both with the support of the Mérieux Foundation. Advances in immunosuppression made possible some unusual transplants of tissue, such as bones, knee-joints, femurs and larynx. From these stemmed the first attempts to transplant hands. This book looks at the long-term results of reattaching hands that have been accidentally amputated. It reviews all the problems -- technical, immunological, nervous, functional and psychological -- that surgeons encountered during and after the transplants. Surgeons, transplant experts, immunologists, dermatologists, psychiatrists, neurophysiologists, physiotherapists and re-education experts will also find here answers to their ethical and legal questions about removing tissue from donors, as well as information about composite tissue grafts in plastic and reconstructive surgery.
Download or read book Atlas of Microsurgical Composite Tissue Transplantation written by Donald Serafin and published by . This book was released on 1995 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a comprehensive discussion of free flap surgery. The author presents an in-depth, technique-oriented review of each flap, including indications, dimensions, vascular and neural anatomy, and dissection. Covers cutaneous, musculocutaneous, septocutaneous, fasciocutaneous and fascial flaps. Each chapter includes a review by selected experts for a unique perspective and alternate surgical techniques.
Download or read book Composite Tissue Transplantation written by Charles W. Hewitt and published by R G Landes Company. This book was released on 1999 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Table of ContentsThe first limb transplant experiments with cyclosporineRelative antigenicity of limb allograft components and differential rejectionInduction of transplantation tolerance in large animal models without long term suppression: strategies to manipulate the immune system of the fetal and adult recipientDendritic cells and alloimmune chimerism in limb transplantationComposite tissue/vascularized bone marrow transplantation: development of donor-host immune chimerism and toleranceVascularized bone marrow transplantation: pathology of composite tissue transplantation-induced tissue a.
Download or read book Atlas of Microsurgical Composite Tissue Transplantation written by and published by . This book was released on 2001 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hand transplantation written by Marco Lanzetta and published by Springer Science & Business Media. This book was released on 2007-03-20 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents international experimental and clinical experience on limb transplantation and other composite tissue allografts, representing the most complete and comprehensive review of this innovative and ground breaking procedure. This book is a milestone in medical literature and an asset for every scientific library.
Download or read book Microsurgical Composite Tissue Transplantation written by and published by . This book was released on 1991 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microsurgical Composite Tissue Transplantation written by Donald Serafin and published by . This book was released on 1979 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book From Auto to Allotransplantation written by F.-C. Wei and published by Karger Medical and Scientific Publishers. This book was released on 2016-06-28 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique publication was written by experts who have made significant contributions to the development of reconstructive microsurgery and vascularized composite allotransplantation and are likely to shape its future. The book is divided into three major sections. The first presents the state-of-the-art of autologous microsurgical reconstruction. It summarizes current achievements, highlights the shortcomings of currently available techniques, and prepares the reader for the next evolutionary step: allotransplantation. Section two is a comprehensive review of allotransplantation, from immunology to surgical techniques. Finally, for those interested in establishing a comprehensive center for vascularized composite allotransplantation, section three provides important lessons from the successful Chang Gung Vascularized Composite Allotransplantation Center. From Auto- to Allotransplantation is indeed the only up-to-date and complete reference available on the topic. Scholars and research fellows interested in transplantation will benefit greatly from this work. It is also an invaluable resource for plastic, orthopedic, hand, ENT, oromaxillofacial, and general surgeons as well as for residents.
Download or read book Overcoming Skin Rejection in Composite Tissue Allotransplantation written by B. Horner and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The application of composite tissue techniques is constrained by the susceptibility of skin to rejection. The aim of this thesis is to improve our understanding of skin rejection and find ways to avoid it, in order to enable expansion of the application of composite tissue transplantation techniques. The first part of the thesis explores the consequences and mechanism of skin rejection in rat models. These studies indicate that in the event of allograft failure, there is minimal damage to the vascular pedicle of a composite tissue allotransplant, even after full rejection, making retransplantation possible. Furthermore, there is only mild damage to the recipient tissues, indicating that the second transplant would not be limited in form or function by recipient tissue bed damage. Finally, the studies indicate that there are significant differences between the mechanism of rejection of skin in composite tissue transplants and conventional skin grafts. This means that much of the historical data relating to skin graft rejection is not necessarily relevant to composite tissue allotransplantation. The second part of the thesis uses swine models to explore ways to overcome skin rejection while avoiding the toxicity of chronic systemic immunosuppression, through tolerance induction, and site specific therapy. Previous experience in organ and composite tissue allotransplantation models are analysed to develop the hypothesis that high-level chimeras are tolerant to vascularised skin allotransplants. In utero and adult chimerism induction models are then used in an attempt to attain moderate-level chimeras. A vascularised skin allotransplant model is developed. Finally, the hypothesis is confirmed with the transplantation of a vascularised skin allotransplant on to moderate-level chimeras with the achievement of tolerance. In addition, site-specific therapy is used in an attempt to avoid the side-effects of chronic high-dose systemic immunosuppression. This led to prolongation of skin survival, but eventual skin rejection.
Download or read book Hand Transplantation An Issue of Hand Clinics E Book written by Gerald Brandacher and published by Elsevier Health Sciences. This book was released on 2011-11-29 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: The History and Evolution of Hand Transplantation, World Experience After More Than a Decade of Clinical Hand Transplantation, How to Establish a Hand Transplant Program, Recipient Selection – Who is the Right Candidate for Hand Transplantation? Donor-related Issues in Hand Transplantation, Surgical and Technical Aspects of Hand Transplantation – Is it Just Another Replant? Functional Outcome After Hand Transplantation – What can be Achieved? Strategies to Enhance Nerve Regeneration, Immunosuppressive Protocols and Immunological Challenges Related to Hand Transplantation, Acute and Chronic Rejection in Hand Transplantation – What have we Learned? Favoring the Risk Benefit Balance for Hand Transplantation – The Pittsburgh Approach Ethical, Financial and Policy Considerations of Hand Transplantation
Download or read book Reconstructive Transplantation and Regenerative Medicine written by Vijay Gorantla and published by CRC Press. This book was released on 2021-11-12 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes rapid progress and innovation in transplantation and regenerative medicine - the merger of reconstructive plastic surgery and transplantation - called Vascularized Composite Allotransplantation. This merger includes face, hand, uteri, larynx, tongue, penis and trachea translplantations as well as other body part transplants using grafts derived from organ donors. These sorts of transplants are now performed more commonly. Cell therapies for immunomodulation are surrogates for immune responses after transplantation to non-invasive imaging of neuroregeneration for improving functional outcomes after transplant.
Download or read book Face Transplantation written by Juan P. Barret and published by Springer. This book was released on 2015-01-21 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together all the relevant available science behind face transplants. It is comprehensive in its coverage, encompassing patient and donor evaluation, ethics, legal issues, psychological issues, types of transplant, surgical technique, issues relating to immunosuppression, follow-up protocols, and current outcomes. Facial transplantation, which allows the replacement of missing anatomy with a perfect match based on transplant medicine principles, has become the most striking innovation in plastic surgery of the twenty-first century as surgeons and scientists progress from reconstructive surgery to restorative surgery. A robust team approach is, however, necessary to produce safe and efficient outcomes, and numerous questions are arising, from technical issues to ethical dilemmas. The reader will discover in this volume all the information required in order to understand this new discipline and to be able to set up a program of facial transplantation.
Download or read book The Know How of Face Transplantation written by Maria Z. Siemionow and published by Springer Science & Business Media. This book was released on 2011-03-29 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is laid out in 6 sections: 1. Preclinical Approaches to Face Transplantation 2. Clinical Aspects in Preparation to Face Transplantation in Humans 3. Approval Process of Face Transplantation in Humans 4. Social and Public Relations in Face Transplantation 5. World Experience with Face Transplantation in Humans 6. Future Directions in Face Transplantation This book spans the entire process of a face transplantation, from detailing the anatomy of the face to considering the social and ethical challenges of the procedure. This rigorous presentation of face transplantation also includes the anesthesia involved, the role of Institutional Review Boards in approving the operation, the financial aspects and media response. Since the authorship is international, the book considers the different perspectives, approaches and responses from across the world.
Download or read book Proceedings of the International Asymposium on Composite Tissue Allotransplantation written by John H. Barker and published by . This book was released on 1998 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Science of Reconstructive Transplantation written by Gerald Brandacher and published by Humana Press. This book was released on 2015-05-13 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents a comprehensive overview of the latest advances in basic and translational research in the field of reconstructive transplantation and its potential therapeutic implications. Dr. Thomas E. Starzl and Dr. Raimund Margreiter, both pioneers in the field of transplantation, have written the foreword for the book. The volume spans such topics as skin rejection, immune monitoring, stem cell-based immunomodulatory strategies, costimulatory blockade, tolerance induction, chronic rejection, ischemia reperfusion injury, nerve regeneration, cortical reintegration, and small and large animal models for reconstructive transplantation. The book is intended for biomedical researchers and basic scientists in the field of reconstructive transplantation, transplant immunology and regenerative medicine, as well as clinicians, surgeons and multidisciplinary specialists, who are practicing or interested in this novel and exciting field. Postgraduate fellows and students will also find it a valuable reference.
