Download or read book Valuation in Life Sciences written by Boris Bogdan and published by Springer Science & Business Media. This book was released on 2010-04-19 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Valuation is a hot topic among life sciences professionals. There is no clear understanding on how to use the different valuation approaches and how to determine input parameters. Some do not value at all, arguing that it is not possible to get realistic and objective numbers out of it. Some claim it to be an art. In the following chapters we will provide the user with a concise val- tion manual, providing transparency and practical insight for all dealing with valuation in life sciences: project and portfolio managers, licensing executives, business developers, technology transfer managers, entrep- neurs, investors, and analysts. The purpose of the book is to explain how to apply discounted cash flow and real options valuation to life sciences p- jects, i.e. to license contracts, patents, and firms. We explain the fun- mentals and the pitfalls with case studies so that the reader is capable of performing the valuations on his own and repeat the theory in the exercises and case studies. The book is structured in five parts: In the first part, the introduction, we discuss the role of the players in the life sciences industry and their p- ticular interests. We describe why valuation is important to them, where they need it, and the current problems to it. The second part deals with the input parameters required for valuation in life sciences, i.e. success rates, costs, peak sales, and timelines.

Download or read book Reference Manual for Magnetic Resonance Safety Implants and Devices written by Frank G. Shellock and published by . This book was released on 2013-01-01 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Reference Manual for Magnetic Resonance Safety, Implants, and Devices: 2013 Edition is an indispensable textbook for radiologists, MRI technologists, facility managers, and other healthcare professionals. This internationally acclaimed, annually revised, and fully updated textbook series is a comprehensive information resource that includes guidelines and recommendations for MRI safety and patient management. The content is based on the latest peer-reviewed publications, labeling information from medical device companies, findings from recent investigations, as well as documents developed by professional and governmental organizations. Importantly, this textbook is a vital source of information for implants and devices evaluated for MRI-related issues. "The List" contains tabulated data for thousands of objects, including products tested at 3-Tesla. Coverage spans the full range of implants and devices encountered in patients referred for MRI procedures.

Download or read book Science Business written by Gary P. Pisano and published by Harvard Business Press. This book was released on 2006 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why has the biotechnology industry failed to perform up to expectations? This book attempts to answer this question by providing a critique of the industry. It reveals the causes of biotech's problems and offers an analysis on how the industry works. It also provides prescriptions for companies, seeking ways to improve the industry's performance.

Download or read book Oncologic Critical Care written by Joseph L. Nates and published by Springer. This book was released on 2019-10-30 with total page 2099 pages. Available in PDF, EPUB and Kindle. Book excerpt: This major reference work is the most comprehensive resource on oncologic critical care. The text reviews all significant aspects of oncologic ICU practices, with a particular focus on challenges encountered in the diagnosis and management of the critically ill cancer patient population. Comprised of over 140 chapters, the text explores such topics as the organization and management of an oncologic ICU, diseases and complications encountered in the oncologic ICU, multidisciplinary care, surgical care, transfusion medicine, special patient populations, critical care procedures, ethics, pain management, and palliative care. Written by worldwide experts in the field, Oncologic Critical Care is a valuable resource for intensivists, advance practice providers, nurses, and other healthcare providers, that will help close significant knowledge and educational gaps within the realm of medical care for critically ill cancer patients.

Download or read book Common Sense on Mutual Funds written by John C. Bogle and published by John Wiley & Sons. This book was released on 1999 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A critical look at the mutual fund industry and how we invest, and ... a compelling course for change."--Jacket.

Download or read book Inorganic Frameworks as Smart Nanomedicines written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2018-04-09 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inorganic Frameworks as Smart Nanocarriers for Drug Delivery brings together recent research in the area of inorganic frameworks for drug delivery. Different types of nanocarriers are presented and discussed in detail, providing an up-to-date overview on inorganic nanoparticles with pharmaceutical applications. Written by a diverse range of international academics, this book is a valuable reference resource for researchers in biomaterials, the pharmaceutical industry, and those who want to learn more about the current applications of inorganic smart nanocarriers. - Includes assembly methods for a variety of smart nanocarrier systems, also showing how they are applied - Highlights how metal-oxide nanoparticles are effectively used in drug delivery - Assesses the pros and cons of different metallic nanomaterials as drug carriers

Download or read book The Australian Official Journal of Trademarks written by and published by . This book was released on 1906 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The History of Oncology written by D. J. Th. Wagener and published by Bohn Stafleu van Loghum. This book was released on 2009-07-13 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: ‘The story of oncology is not only fascinating but also contains many accounts of dead ends, chance discoveries, illusions, mistakes and disappointments alongside the few successes.’These words are taken from the introduction to this book. The author, professor emeritus of Medical Oncology, reviews all aspects of the problem of cancer from a historical perspective, from the oldest existing records to the latest scientific and medical advances. It will interest the many people engaged in the treatment of cancer to read how the current therapeutic methods came about, and the book may also provide inspiration for cancer researchers, and for all those directly or indirectly involved with cancer. The layman looking for background information on a particular treatment may find it useful too. The various chapters can be read independently. A glossary and a few explanatory diagrams augment the text.This book grew out of an invitation the author received to lecture on the history of oncology. During his background reading, he discovered that there was no single volume dealing with the entire history of the subject. Fortunately, however, a great deal of information could be found here and there in the literature. As he read, he was struck by the fascinating stories behind many discoveries, and felt impelled to put them together in a single comprehensive account. The results of his labors are presented in this remarkable volume.The author, Prof. D.J.Th. (Theo) Wagener, was head of the department of Medical Oncology at the Radboud University Nijmegen Medical Centre in the Netherlands from 1982 to 2001, chairman of the Educational Committee of the European Society of Medical Oncology (ESMO), a member of the Educational Committee of the American Society of Clinical Oncology (ASCO) and a member of various international scientific working groups, mainly of the European Organization for Research and Treatment of Cancer (EORTC).

Download or read book Imaging of Head and Neck Cancer written by A. T. Ahuja and published by Cambridge University Press. This book was released on 2003-01-06 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise integrated handbook looks at all available imaging methods for head and neck cancer, highlighting the strengths and weaknesses of each method. The information is provided in a clinical context and will guide radiologists as to the information the clinician actually needs when managing a patient with head and neck cancer. It will also provide the clinician with the advantages and limitations of imaging. The text therefore deals with Ultrasound, CT and MRI. The initial chapters aim to give the reader a core knowledge, which can be used in imaging by the various methods described. The subsequent chapters are directed towards clinical problems and deal with the common cancers in a logical order.

Download or read book Porous Silicon in Practice written by M. J. Sailor and published by John Wiley & Sons. This book was released on 2012-01-09 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: By means of electrochemical treatment, crystalline silicon can be permeated with tiny, nanostructured pores that entirely change the characteristics and properties of the material. One prominent example of this can be seen in the interaction of porous silicon with living cells, which can be totally unwilling to settle on smooth silicon surfaces but readily adhere to porous silicon, giving rise to great hopes for such future applications as programmable drug delivery or advanced, braincontrolled prosthetics. Porous silicon research is active in the fields of sensors, tissue engineering, medical therapeutics and diagnostics, photovoltaics, rechargeable batteries, energetic materials, photonics, and MEMS (Micro Electro Mechanical Systems). Written by an outstanding, well-recognized expert in the field, this book provides detailed, step-by-step instructions to prepare and characterize the major types of porous silicon. It is intended for those new to the fi eld. Sampling of topics covered: * Principles of Etching Porous Silicon * Etch Cell Construction and Considerations * Photonic Crystals, Microcavities, and Bragg Stacks Etched in Silicon * Preparation of Free-standing Films and Particles of Porous Silicon * Preparation of Photoluminescent Nanoparticles from Porous Silicon * Preparation of Silicon Nanowires by Electrochemical Etch of Silicon * Surface Modifi cation Chemistry and Biochemistry * Measurement of Optical Properties * Measurement of Pore Size, Porosity, Thickness, Surface Area The whole is backed by a generous use of color photographs to illustrate the described procedures in detail, plus a bibliography of further literature pertinent to a wide range of application fi elds. For materials scientists, chemists, physicists, optical physicists, biomaterials scientists, neurobiologists, bioengineers, and graduate students in those fields, as well as those working in the semiconductor industry.

Download or read book Ultrasonography of the Pancreas written by Mirko D'Onofrio and published by Springer Science & Business Media. This book was released on 2012-03-08 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultrasonography (US) has long been considered an important diagnostic imaging modality for investigation of the pancreas despite certain significant and well-known limitations. Indeed, in many countries US represents the first step in the diagnostic algorithm for pancreatic pathologies. Recent years have witnessed major advances in conventional, harmonic, and Doppler imaging. New technologies, softwares, and techniques, such as volumetric imaging, enhancement quantification, and fusion imaging, are increasing the diagnostic capabilities of US. The injection of microbubble contrast agents allows better tissue characterization with definitive differentiation between solid and cystic lesions. Contrast-enhanced US improves the characterization of pancreatic tumors, assists in local and liver staging, and can offer savings in both time and money. Acoustic radiation force impulse (ARFI) imaging is a promising new US method to test, without manual compression, the mechanical strain properties of deep tissues. Furthermore, the applications and indications for interventional, endoscopic, and intraoperative US have undergone significant improvement and refinement. This book provides a complete overview of all these technological developments and their impact on the assessment of pancreatic pathologies. Percutaneous, endoscopic, and intraoperative US of the pancreas are discussed in detail, with precise description of findings and with informative imaging (CT and MRI) and pathologic correlations.

Download or read book Immunotherapy of Hepatocellular Carcinoma written by Tim F. Greten and published by Springer. This book was released on 2018-08-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.

Download or read book Brachytherapy Physics written by Bruce Thomadsen and published by Medical Physics Publishing Corporation. This book was released on 2005 with total page 965 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is organized into 6 sections: Fundamentals; Dosimetry; Interstitial Fundamentals; Interstitial Applications; Intercavitary Applications for Gynecological Cancer, and Unconventiional Delivery Systems. The book includes a CD-ROM containing an electronic version of the book (with many illustrations in full color) plus a compiled list of references.

Download or read book Science Lessons written by Gordon M. Binder and published by Harvard Business Review Press. This book was released on 2008 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Under Gordon Binder's leadership, Amgen became the world's largest and most successful biotech company in the world. This text describes what it really takes to manage risk, financing, creative employees, and intellectual property on the international stage.

Download or read book MRI Bioeffects Safety and Patient Management written by Frank G. Shellock, Ed. and published by . This book was released on 2013-09-01 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: MRI Bioeffects, Safety, and Patient Management is a comprehensive, authoritative textbook on the health and safety concerns of MRI technology that contains contributions from more than forty internationally respected experts in the field. This textbook includes both theoretical and practical information and serves as the definitive resource for radiologists and other physicians, MRI technologists, physicists, scientists, MRI facility managers, and others. The text begins with a discussion of basic MRI physics and then proceeds to a description of the bioeffects of static, gradient, and radiofrequency electromagnetic fields as well as the risks associated with acoustic noise. It then discusses the use of MRI during pregnancy, the design of an MRI facility to support safety, the procedures to screen patients and other individuals, and the management of patients with claustrophobia, anxiety, or emotional distress. Other chapters cover the safety of MRI contrast agents, the use of ferromagnetic detection systems, techniques for physiological monitoring, the unique safety needs of interventional MRI centers, and the administration of sedation and anesthesia during MRI. Detailed descriptions covering the proper management of patients with metallic implants and complex electronically activated devices, such as cardiac pacemakers and neuromodulation systems, are included. MRI safety policies and procedures are presented for hospitals/medical centers, outpatient facilities, children's hospitals, and research facilities. Finally, MRI standards and guidelines are provided for the United States, Europe, Canada, and Australia.

Download or read book Porous Silicon for Biomedical Applications written by Hélder A. Santos and published by Elsevier. This book was released on 2021-10-27 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Porous Silicon for Biomedical Applications, Second Edition, provides an updated guide to the diverse range of biomedical applications of porous silicon, from biosensing and imaging to tissue engineering and cancer therapy. Across biomedical disciplines, there is an ongoing search for biomaterials that are biocompatible, modifiable, structurally sound, and versatile. Porous silicon possesses a range of properties that make it ideal for a variety of biomedical applications, such as controllable geometry, tunable nanoporous structure, large pore volume/high specific surface area, and versatile surface chemistry. This book provides a fully updated and detailed overview of the range of biomedical applications for porous silicon. Part One offers the reader a helpful insight into the fundamentals and beneficial properties of porous silicon, including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein modification, and biocompatibility. The book then builds on the systematic detailing of each biomedical application using porous silicon, from bioimaging and sensing to drug delivery and tissue engineering. This new edition also includes new chapters on in-vivo assessment of porous silicon, photodynamic and photothermal therapy, micro- and nanoneedles, Raman imaging, cancer immunotherapy, and more. With its acclaimed editor and international team of expert contributors, Porous Silicon for Biomedical Applications, Second Edition, is a technical resource and indispensable guide for all those involved in the research, development, and application of porous silicon and other biomaterials, while providing a comprehensive introduction for students and academics interested in this field. Reviews the fundamental aspects of porous silicon, including the fabrication and unique properties of this useful material. Discusses a broad selection of biomedical applications, offering a detailed insight into the benefits of porous silicon in both research and clinical settings. Includes fully updated content from the previous edition, as well as brand new chapters, covering topics such as porous silicon micro- and nanoneedles, and cancer immunotherapy.

Download or read book Image Guided Cancer Therapy written by Damian E. Dupuy and published by Springer. This book was released on 2013-08-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Image-Guided Cancer Therapy: A Multidisciplinary Approach provides clinicians with in-depth coverage of the growing, dynamic field of interventional oncology. Combining the knowledge of expert editors and authors into one powerhouse reference, this book looks at tumor ablation, HIFU, embolic therapies, emerging technologies, and radiation therapy throughout the body (liver, bone, breast, gynecologic and prostate cancers, to name just a few) , and includes discussion of different imaging modalities. In the words of Peter Mueller, MD, author of the book’s Foreword: “... The senior authors are all world renowned experts in interventional oncology, which is another example of the high quality authorship and experience that is brought to this book. The later chapters discuss therapies that are simply not covered in any other source. Everyone who is doing or wants to do ablation therapies and interventional oncology will face a time when they will be asked to use their expertise in less used and less investigated areas. There is nowhere else where the reader can get information on the prostate, breast, and gynecologic areas, and especially pediatrics....This book is an outstanding contribution to the literature and will become a ‘must read’ for all physicians who are interested in Interventional Oncology.”