Download or read book Common Statistical Methods for Clinical Research with SAS Examples Third Edition written by Glenn Walker and published by SAS Institute. This book was released on 2010-02-15 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glenn Walker and Jack Shostak's Common Statistical Methods for Clinical Research with SAS Examples, Third Edition, is a thoroughly updated edition of the popular introductory statistics book for clinical researchers. This new edition has been extensively updated to include the use of ODS graphics in numerous examples as well as a new emphasis on PROC MIXED. Straightforward and easy to use as either a text or a reference, the book is full of practical examples from clinical research to illustrate both statistical and SAS methodology. Each example is worked out completely, step by step, from the raw data. Common Statistical Methods for Clinical Research with SAS Examples, Third Edition, is an applications book with minimal theory. Each section begins with an overview helpful to nonstatisticians and then drills down into details that will be valuable to statistical analysts and programmers. Further details, as well as bonus information and a guide to further reading, are presented in the extensive appendices. This text is a one-source guide for statisticians that documents the use of the tests used most often in clinical research, with assumptions, details, and some tricks--all in one place. This book is part of the SAS Press program.
Download or read book Common Statistical Methods for Clinical Research with SAS Examples Third Edition written by Glenn A. Walker and published by SAS Institute. This book was released on 2010-02-15 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glenn Walker and Jack Shostak's Common Statistical Methods for Clinical Research with SAS Examples, Third Edition, is a thoroughly updated edition of the popular introductory statistics book for clinical researchers. This new edition has been extensively updated to include the use of ODS graphics in numerous examples as well as a new emphasis on PROC MIXED. Straightforward and easy to use as either a text or a reference, the book is full of practical examples from clinical research to illustrate both statistical and SAS methodology. Each example is worked out completely, step by step, from the raw data. Common Statistical Methods for Clinical Research with SAS Examples, Third Edition, is an applications book with minimal theory. Each section begins with an overview helpful to nonstatisticians and then drills down into details that will be valuable to statistical analysts and programmers. Further details, as well as bonus information and a guide to further reading, are presented in the extensive appendices. This text is a one-source guide for statisticians that documents the use of the tests used most often in clinical research, with assumptions, details, and some tricks--all in one place. This book is part of the SAS Press program.
Download or read book Common Statistical Methods for Clinical Research with SAS Examples written by Glenn A. Walker and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Common Statistical Methods for Clinical Research with SAS Examples written by Glenn A. Walker and published by Sas Inst. This book was released on 2002 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated edition provides clinical researchers with an invaluable aid for understanding the statistical methods cited most frequently in clinical protocols, statistical analysis plans, clinical and statistical reports, and medical journals. The text is written in a way that takes the non-statistician through each test using examples, yet substantive details are presented that benefit even the most experienced data analysts.
Download or read book Introduction to Statistical Methods for Clinical Trials written by Thomas D. Cook and published by CRC Press. This book was released on 2007-11-19 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials have become essential research tools for evaluating the benefits and risks of new interventions for the treatment and prevention of diseases, from cardiovascular disease to cancer to AIDS. Based on the authors’ collective experiences in this field, Introduction to Statistical Methods for Clinical Trials presents various statistical topics relevant to the design, monitoring, and analysis of a clinical trial. After reviewing the history, ethics, protocol, and regulatory issues of clinical trials, the book provides guidelines for formulating primary and secondary questions and translating clinical questions into statistical ones. It examines designs used in clinical trials, presents methods for determining sample size, and introduces constrained randomization procedures. The authors also discuss how various types of data must be collected to answer key questions in a trial. In addition, they explore common analysis methods, describe statistical methods that determine what an emerging trend represents, and present issues that arise in the analysis of data. The book concludes with suggestions for reporting trial results that are consistent with universal guidelines recommended by medical journals. Developed from a course taught at the University of Wisconsin for the past 25 years, this textbook provides a solid understanding of the statistical approaches used in the design, conduct, and analysis of clinical trials.
Download or read book Analysis of Clinical Trials Using SAS written by Alex Dmitrienko and published by SAS Institute. This book was released on 2017-07-17 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analysis of Clinical Trials Using SAS®: A Practical Guide, Second Edition bridges the gap between modern statistical methodology and real-world clinical trial applications. Tutorial material and step-by-step instructions illustrated with examples from actual trials serve to define relevant statistical approaches, describe their clinical trial applications, and implement the approaches rapidly and efficiently using the power of SAS. Topics reflect the International Conference on Harmonization (ICH) guidelines for the pharmaceutical industry and address important statistical problems encountered in clinical trials. Commonly used methods are covered, including dose-escalation and dose-finding methods that are applied in Phase I and Phase II clinical trials, as well as important trial designs and analysis strategies that are employed in Phase II and Phase III clinical trials, such as multiplicity adjustment, data monitoring, and methods for handling incomplete data. This book also features recommendations from clinical trial experts and a discussion of relevant regulatory guidelines. This new edition includes more examples and case studies, new approaches for addressing statistical problems, and the following new technological updates: SAS procedures used in group sequential trials (PROC SEQDESIGN and PROC SEQTEST) SAS procedures used in repeated measures analysis (PROC GLIMMIX and PROC GEE) macros for implementing a broad range of randomization-based methods in clinical trials, performing complex multiplicity adjustments, and investigating the design and analysis of early phase trials (Phase I dose-escalation trials and Phase II dose-finding trials) Clinical statisticians, research scientists, and graduate students in biostatistics will greatly benefit from the decades of clinical research experience and the ready-to-use SAS macros compiled in this book.
Download or read book Statistical Analysis of Designed Experiments written by Helge Toutenburg and published by Springer Science & Business Media. This book was released on 2006-05-09 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unique in commencing with relatively simple statistical concepts and ideas found in most introductory statistical textbooks, this book goes on to cover more material useful for undergraduates and graduate in statistics and biostatistics.
Download or read book Understanding Advanced Statistical Methods written by Peter Westfall and published by CRC Press. This book was released on 2013-04-09 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a much-needed bridge between elementary statistics courses and advanced research methods courses, Understanding Advanced Statistical Methods helps students grasp the fundamental assumptions and machinery behind sophisticated statistical topics, such as logistic regression, maximum likelihood, bootstrapping, nonparametrics, and Bayesian methods. The book teaches students how to properly model, think critically, and design their own studies to avoid common errors. It leads them to think differently not only about math and statistics but also about general research and the scientific method. With a focus on statistical models as producers of data, the book enables students to more easily understand the machinery of advanced statistics. It also downplays the "population" interpretation of statistical models and presents Bayesian methods before frequentist ones. Requiring no prior calculus experience, the text employs a "just-in-time" approach that introduces mathematical topics, including calculus, where needed. Formulas throughout the text are used to explain why calculus and probability are essential in statistical modeling. The authors also intuitively explain the theory and logic behind real data analysis, incorporating a range of application examples from the social, economic, biological, medical, physical, and engineering sciences. Enabling your students to answer the why behind statistical methods, this text teaches them how to successfully draw conclusions when the premises are flawed. It empowers them to use advanced statistical methods with confidence and develop their own statistical recipes. Ancillary materials are available on the book’s website.
Download or read book Implementing CDISC Using SAS written by Chris Holland and published by SAS Institute. This book was released on 2019-05-30 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades researchers and programmers have used SAS to analyze, summarize, and report clinical trial data. Now Chris Holland and Jack Shostak have updated their popular Implementing CDISC Using SAS, the first comprehensive book on applying clinical research data and metadata to the Clinical Data Interchange Standards Consortium (CDISC) standards. Implementing CDISC Using SAS: An End-to-End Guide, Revised Second Edition, is an all-inclusive guide on how to implement and analyze the Study Data Tabulation Model (SDTM) and the Analysis Data Model (ADaM) data and prepare clinical trial data for regulatory submission. Updated to reflect the 2017 FDA mandate for adherence to CDISC standards, this new edition covers creating and using metadata, developing conversion specifications, implementing and validating SDTM and ADaM data, determining solutions for legacy data conversions, and preparing data for regulatory submission. The book covers products such as Base SAS, SAS Clinical Data Integration, and the SAS Clinical Standards Toolkit, as well as JMP Clinical. Topics included in this edition include an implementation of the Define-XML 2.0 standard, new SDTM domains, validation with Pinnacle 21 software, event narratives in JMP Clinical, STDM and ADAM metadata spreadsheets, and of course new versions of SAS and JMP software. The second edition was revised to add the latest C-Codes from the most recent release as well as update the make_define macro that accompanies this book in order to add the capability to handle C-Codes. The metadata spreadsheets were updated accordingly. Any manager or user of clinical trial data in this day and age is likely to benefit from knowing how to either put data into a CDISC standard or analyzing and finding data once it is in a CDISC format. If you are one such person--a data manager, clinical and/or statistical programmer, biostatistician, or even a clinician--then this book is for you.
Download or read book Research Design Statistical Analysis written by Arnold D. Well and published by Psychology Press. This book was released on 2003-01-30 with total page 871 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Free CD contains several real and artificial data sets used in the book in SPSS, SYSTAT, and ASCII formats"--Cover
Download or read book SAS Programming in the Pharmaceutical Industry Second Edition written by Jack Shostak and published by SAS Institute. This book was released on 2014-03-01 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive resource provides on-the-job training for statistical programmers who use SAS in the pharmaceutical industry This one-stop resource offers a complete review of what entry- to intermediate-level statistical programmers need to know in order to help with the analysis and reporting of clinical trial data in the pharmaceutical industry. SAS Programming in the Pharmaceutical Industry, Second Edition begins with an introduction to the pharmaceutical industry and the work environment of a statistical programmer. Then it gives a chronological explanation of what you need to know to do the job. It includes information on importing and massaging data into analysis data sets, producing clinical trial output, and exporting data. This edition has been updated for SAS 9.4, and it features new graphics as well as all new examples using CDISC SDTM or ADaM model data structures. Whether you're a novice seeking an introduction to SAS programming in the pharmaceutical industry or a junior-level programmer exploring new approaches to problem solving, this real-world reference guide offers a wealth of practical suggestions to help you sharpen your skills. This book is part of the SAS Press program.
Download or read book A Handbook of Statistical Graphics Using SAS ODS written by Geoff Der and published by CRC Press. This book was released on 2014-08-15 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Easily Use SAS to Produce Your Graphics Diagrams, plots, and other types of graphics are indispensable components in nearly all phases of statistical analysis, from the initial assessment of the data to the selection of appropriate statistical models to the diagnosis of the chosen models once they have been fitted to the data. Harnessing the full graphics capabilities of SAS, A Handbook of Statistical Graphics Using SAS ODS covers essential graphical methods needed in every statistician’s toolkit. It explains how to implement the methods using SAS 9.4. The handbook shows how to use SAS to create many types of statistical graphics for exploring data and diagnosing fitted models. It uses SAS’s newer ODS graphics throughout as this system offers a number of advantages, including ease of use, high quality of results, consistent appearance, and convenient semiautomatic graphs from the statistical procedures. Each chapter deals graphically with several sets of example data from a wide variety of areas, such as epidemiology, medicine, and psychology. These examples illustrate the use of graphic displays to give an overview of data, to suggest possible hypotheses for testing new data, and to interpret fitted statistical models. The SAS programs and data sets are available online.
Download or read book Pharmaceutical Statistics Using SAS written by Alex Dmitrienko, Ph.D. and published by SAS Institute. This book was released on 2007-02-07 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces a range of data analysis problems encountered in drug development and illustrates them using case studies from actual pre-clinical experiments and clinical studies. Includes a discussion of methodological issues, practical advice from subject matter experts, and review of relevant regulatory guidelines.
Download or read book Epidemiology written by Mark Woodward and published by CRC Press. This book was released on 2013-12-19 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highly praised for its broad, practical coverage, the second edition of this popular text incorporated the major statistical models and issues relevant to epidemiological studies. Epidemiology: Study Design and Data Analysis, Third Edition continues to focus on the quantitative aspects of epidemiological research. Updated and expanded, this edition shows students how statistical principles and techniques can help solve epidemiological problems. New to the Third Edition New chapter on risk scores and clinical decision rules New chapter on computer-intensive methods, including the bootstrap, permutation tests, and missing value imputation New sections on binomial regression models, competing risk, information criteria, propensity scoring, and splines Many more exercises and examples using both Stata and SAS More than 60 new figures After introducing study design and reviewing all the standard methods, this self-contained book takes students through analytical methods for both general and specific epidemiological study designs, including cohort, case-control, and intervention studies. In addition to classical methods, it now covers modern methods that exploit the enormous power of contemporary computers. The book also addresses the problem of determining the appropriate size for a study, discusses statistical modeling in epidemiology, covers methods for comparing and summarizing the evidence from several studies, and explains how to use statistical models in risk forecasting and assessing new biomarkers. The author illustrates the techniques with numerous real-world examples and interprets results in a practical way. He also includes an extensive list of references for further reading along with exercises to reinforce understanding. Web Resource A wealth of supporting material can be downloaded from the book’s CRC Press web page, including: Real-life data sets used in the text SAS and Stata programs used for examples in the text SAS and Stata programs for special techniques covered Sample size spreadsheet
Download or read book Statistical and Machine Learning Data Mining written by Bruce Ratner and published by CRC Press. This book was released on 2017-07-12 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in predictive analytics of big data has grown exponentially in the four years since the publication of Statistical and Machine-Learning Data Mining: Techniques for Better Predictive Modeling and Analysis of Big Data, Second Edition. In the third edition of this bestseller, the author has completely revised, reorganized, and repositioned the original chapters and produced 13 new chapters of creative and useful machine-learning data mining techniques. In sum, the 43 chapters of simple yet insightful quantitative techniques make this book unique in the field of data mining literature. What is new in the Third Edition: The current chapters have been completely rewritten. The core content has been extended with strategies and methods for problems drawn from the top predictive analytics conference and statistical modeling workshops. Adds thirteen new chapters including coverage of data science and its rise, market share estimation, share of wallet modeling without survey data, latent market segmentation, statistical regression modeling that deals with incomplete data, decile analysis assessment in terms of the predictive power of the data, and a user-friendly version of text mining, not requiring an advanced background in natural language processing (NLP). Includes SAS subroutines which can be easily converted to other languages. As in the previous edition, this book offers detailed background, discussion, and illustration of specific methods for solving the most commonly experienced problems in predictive modeling and analysis of big data. The author addresses each methodology and assigns its application to a specific type of problem. To better ground readers, the book provides an in-depth discussion of the basic methodologies of predictive modeling and analysis. While this type of overview has been attempted before, this approach offers a truly nitty-gritty, step-by-step method that both tyros and experts in the field can enjoy playing with.
Download or read book Basic Statistics Using SAS Enterprise Guide written by Geoff Der and published by SAS Press. This book was released on 2007 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing the practical aspects of SAS analysis, this example-rich guide shows users how to conduct a wide range of statistical analyses without any SAS programming required. Exercises at the end of each chapter help readers consolidate what they have learned.
Download or read book Theory and Methods of Statistics written by P.K. Bhattacharya and published by Academic Press. This book was released on 2016-06-23 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theory and Methods of Statistics covers essential topics for advanced graduate students and professional research statisticians. This comprehensive resource covers many important areas in one manageable volume, including core subjects such as probability theory, mathematical statistics, and linear models, and various special topics, including nonparametrics, curve estimation, multivariate analysis, time series, and resampling. The book presents subjects such as "maximum likelihood and sufficiency," and is written with an intuitive, heuristic approach to build reader comprehension. It also includes many probability inequalities that are not only useful in the context of this text, but also as a resource for investigating convergence of statistical procedures. Codifies foundational information in many core areas of statistics into a comprehensive and definitive resource Serves as an excellent text for select master’s and PhD programs, as well as a professional reference Integrates numerous examples to illustrate advanced concepts Includes many probability inequalities useful for investigating convergence of statistical procedures
