Download or read book Combinatorial Problems from Mapping and Reading DNA Sequences written by Daniela Renate Martin and published by . This book was released on 1995 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Introduction to Computational Biology written by Michael S. Waterman and published by CRC Press. This book was released on 2018-05-02 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology is in the midst of a era yielding many significant discoveries and promising many more. Unique to this era is the exponential growth in the size of information-packed databases. Inspired by a pressing need to analyze that data, Introduction to Computational Biology explores a new area of expertise that emerged from this fertile field- the combination of biological and information sciences. This introduction describes the mathematical structure of biological data, especially from sequences and chromosomes. After a brief survey of molecular biology, it studies restriction maps of DNA, rough landmark maps of the underlying sequences, and clones and clone maps. It examines problems associated with reading DNA sequences and comparing sequences to finding common patterns. The author then considers that statistics of pattern counts in sequences, RNA secondary structure, and the inference of evolutionary history of related sequences. Introduction to Computational Biology exposes the reader to the fascinating structure of biological data and explains how to treat related combinatorial and statistical problems. Written to describe mathematical formulation and development, this book helps set the stage for even more, truly interdisciplinary work in biology.
Download or read book Mapping and Sequencing the Human Genome written by National Research Council and published by National Academies Press. This book was released on 1988-01-01 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
Download or read book Very Large Scale Computation in the 21st Century written by Jill P. Mesirov and published by SIAM. This book was released on 1991-01-01 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text on very large scale computation in the 21st century covers such topics as: challenges in the natural sciences and physics; chemistry; fluid dynamics; astrophysics; biology; challenges in engineering; challenges in algorithm design; and challenges in system design.
Download or read book Handbook of Combinatorics written by R.L. Graham and published by Elsevier. This book was released on 1995-12-11 with total page 2404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Combinatorics
Download or read book String Processing and Information Retrieval written by Mario A. Nascimento and published by Springer Science & Business Media. This book was released on 2003-09-29 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 10th International Symposium on String Processing and Information Retrieval, SPIRE 2003, held in Manaus, Brazil, in October 2003. The 21 revised full papers and 6 revised short papers presented together with 2 invited papers were carefully reviewed and selected from 54 submissions. The papers are organized in topical sections on Web algorithms, bit-parallel algorithms, compression, categorization and ranking, music retrieval, multilingual information retrieval, subsequences and distributed algorithms, and algorithms on strings and trees.
Download or read book Computational Methods for Next Generation Sequencing Data Analysis written by Ion Mandoiu and published by John Wiley & Sons. This book was released on 2016-09-12 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces readers to core algorithmic techniques for next-generation sequencing (NGS) data analysis and discusses a wide range of computational techniques and applications This book provides an in-depth survey of some of the recent developments in NGS and discusses mathematical and computational challenges in various application areas of NGS technologies. The 18 chapters featured in this book have been authored by bioinformatics experts and represent the latest work in leading labs actively contributing to the fast-growing field of NGS. The book is divided into four parts: Part I focuses on computing and experimental infrastructure for NGS analysis, including chapters on cloud computing, modular pipelines for metabolic pathway reconstruction, pooling strategies for massive viral sequencing, and high-fidelity sequencing protocols. Part II concentrates on analysis of DNA sequencing data, covering the classic scaffolding problem, detection of genomic variants, including insertions and deletions, and analysis of DNA methylation sequencing data. Part III is devoted to analysis of RNA-seq data. This part discusses algorithms and compares software tools for transcriptome assembly along with methods for detection of alternative splicing and tools for transcriptome quantification and differential expression analysis. Part IV explores computational tools for NGS applications in microbiomics, including a discussion on error correction of NGS reads from viral populations, methods for viral quasispecies reconstruction, and a survey of state-of-the-art methods and future trends in microbiome analysis. Computational Methods for Next Generation Sequencing Data Analysis: Reviews computational techniques such as new combinatorial optimization methods, data structures, high performance computing, machine learning, and inference algorithms Discusses the mathematical and computational challenges in NGS technologies Covers NGS error correction, de novo genome transcriptome assembly, variant detection from NGS reads, and more This text is a reference for biomedical professionals interested in expanding their knowledge of computational techniques for NGS data analysis. The book is also useful for graduate and post-graduate students in bioinformatics.
Download or read book Combinatorial Pattern Matching written by Amihood Amir and published by Springer Science & Business Media. This book was released on 2010-06 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: The LNCS series reports state-of-the-art results in computer science research, development, and education, at a high level and in both printed and electronic form. Enjoying tight cooperation with the R&D community, with numerous individuals, as well as with prestigious organizations and societies, LNCS has grown into the most comprehensive computer science research forum available. The scope of LNCS, including its subseries LNAI and LNBI, spans the whole range of computer science and information technology including interdisciplinary topics in a variety of application fields. The type of material published traditionally includes -proceedings (published in time for the respective conference) -post-proceedings (consisting of thoroughly revised final full papers) -research monographs (which may be based on outstanding PhD work, research projects, technical reports, etc.) More recently, several color-cover sublines have been added featuring, beyond a collection of papers, various added-value components; these sublines include -tutorials (textbook-like monographs or collections of lectures given at advanced courses) -state-of-the-art surveys (offering complete and mediated coverage of a topic) -hot topics (introducing emergent topics to the broader community)
Download or read book Algorithms and Hardness Results for DNA Physical Mapping Protein Identification and Related Combinatorial Problems written by Mark Cieliebak and published by . This book was released on 2003 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Computing and Combinatorics written by Dingzhu Du and published by Springer Science & Business Media. This book was released on 1995 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the proceedings of the First Annual International Conference on Computing and Combinatorics, COCOON '95, held in Xi'an, China in August 1995. The 52 thoroughly refereed full papers and the 22 short presentations included in this volume were selected from a total of 120 submissions. All current aspects of theoretical computer science and combinatorial mathematics related to computing are addressed; in particular, there are sections on complexity theory, graph drawing, computational geometry, databases, graph algorithms, distributed programming and logic, combinatorics, machine models, combinatorial designs, algorithmic learning, algorithms, distributed computing, and scheduling.
Download or read book Combinatorial Optimization and Application to DNA Sequence Analysis written by Kapil Gupta and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: With recent and continuing advances in bioinformatics, the volume of sequence data has increased tremendously. Along with this increase, there is a growing need to develop efficient algorithms to process such data in order to make useful and important discoveries. Careful analysis of genomic data will benefit science and society in numerous ways, including the understanding of protein sequence functions, early detection of diseases, and finding evolutionary relationships that exist among various organisms. Most sequence analysis problems arising from computational genomics and evolutionary biology fall into the class of NP-complete problems. Advances in exact and approximate algorithms to address these problems are critical. In this thesis, we investigate a novel graph theoretical model that deals with fundamental evolutionary problems. The model allows incorporation of the evolutionary operations ``insertion', ``deletion', and ``substitution', and various parameters such as relative distances and weights. By varying appropriate parameters and weights within the model, several important combinatorial problems can be represented, including the weighted supersequence, weighted superstring, and weighted longest common sequence problems. Consequently, our model provides a general computational framework for solving a wide variety of important and difficult biological sequencing problems, including the multiple sequence alignment problem, and the problem of finding an evolutionary ancestor of multiple sequences. In this thesis, we develop large scale combinatorial optimization techniques to solve our graph theoretical model. In particular, we formulate the problem as two distinct but related models: constrained network flow problem and weighted node packing problem. The integer programming models are solved in a branch and bound setting using simultaneous column and row generation. The methodology developed will also be useful to solve large scale integer programming problems arising in other areas such as transportation and logistics.
Download or read book Algorithms on Strings Trees and Sequences written by Dan Gusfield and published by Cambridge University Press. This book was released on 1997-05-28 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes a range of string problems in computer science and molecular biology and the algorithms developed to solve them.
Download or read book String Processing and Information Retrieval written by and published by . This book was released on 2003 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Applied Combinatorics written by Fred Roberts and published by CRC Press. This book was released on 2009-06-03 with total page 889 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now with solutions to selected problems, Applied Combinatorics, Second Edition presents the tools of combinatorics from an applied point of view. This bestselling textbook offers numerous references to the literature of combinatorics and its applications that enable readers to delve more deeply into the topics.After introducing fundamental counting
Download or read book A Bibliography on Computational Molecular Biology and Genetics written by Sarah Barron and published by DIANE Publishing. This book was released on 1991 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a definitive bibliographic review of the literature related to DNA mapping and sequence analysis, with a focus on computer and mathematical aspects of molecular biology and genetics. Over 2200 entries, arranged by author's name.
Download or read book Some Combinatorial Problems Concerning DNA Arrays written by Earl Hubbell and published by . This book was released on 2001 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mathematical Support for Molecular Biology written by Martin Farach-Colton and published by American Mathematical Soc.. This book was released on 1999 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume features highlights from the DIMACS Special Year on "Mathematical Support for Molecular Biology". Top researchers presented both new research results and comprehensive overviews on the use of mathematics (especially discrete mathematics) and theoretical computer science in molecular biology. The book provides a unique "snapshot" of this growing area of study. It will be of interest to both experts and novices seeking information on the state of the research.
