Download or read book Combinatorial Materials Science written by Marc D. Porter and published by John Wiley & Sons. This book was released on 2007-08-17 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combinatorial Materials Science describes new developments and research results in catalysts, biomaterials, and nanomaterials, together with informatics approaches to the analysis of Combinatorial Science (CombiSci) data. CombiSci has been used extensively in the pharmaceutical industry, but there is enormous potential in its application to materials design and characterization. Addressing advances and applications in both fields, Combinatorial Materials Science: Integrates the scientific fundamentals and interdisciplinary underpinnings required to develop and apply CombiSci concepts Discusses the development and use of CombiSci for the systematic and accelerated investigation of new phenomena and of the complex structure-function interplay in materials Covers the development of new library design strategies for materials processing and for high-throughput tools for rapid sampling Uses a unique, unified approach of applying combinatorial methods to unravel the non-linear structure-function relationships in diverse materials (both hard and soft), together with advances in informatics With chapters written by leading researchers in their specialty areas, this authoritative guide is a must-have resource for scientists and engineers in materials science research, biochemists, chemists, immunologists, cell biologists, polymer scientists, chemical and mechanical engineers, statisticians, and computer scientists. It is also a great text for graduate-level courses in materials science/engineering, polymer science, chemical engineering, and chemistry.
Download or read book High Throughput Analysis written by Radislav A. Potyrailo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, edited by Potyrailo and Amis, addresses a new paradigm-shifting approach in the search for new materials-Combinatorial Materials Science. One way to consider such an approach is to imagine an adventurous chef who decides to look for new entrees by cooking food ingredients in many pots using different combinations in every pot, and boil ing, steaming, or frying them in various ways. Although most of the pots will not have the tastiest food ever devised, some recipes will taste intriguing, and some eventually will lead to a discovery of a new fascinating cuisine. Of course, having a skilled chef design the com binatorial formulation will certainly be helpful in ensuring a successful outcome. Similar to food, each engineering material is a complex product of its chemical composition, structure, and processing. Generally, each of these components matters---change one and you get another material. Most of these "new" materials will be less good than ones we use now since existing materials have been refined with the extensive work of scientists and engi neers. At the same time if one prepares diverse materials like our adventurous chef, chang ing material composition, processing conditions and time, etc. , some of these materials will be superior to existing ones and a few might represent breakout technology.
Download or read book Combinatorial Materials Synthesis written by Xiao-Dong Xiang and published by CRC Press. This book was released on 2003-08-19 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pioneered by the pharmaceutical industry and adapted for the purposes of materials science and engineering, the combinatorial method is now widely considered a watershed in the accelerated discovery, development, and optimization of new materials. Combinatorial Materials Synthesis reveals the gears behind combinatorial materials chemistry and thin-film technology, and discusses the prime techniques involved in synthesis and property determination for experimentation with a variety of materials. Funneling historic innovations into one source, the book explores core approaches to synthesis and rapid characterization techniques for work with combinatorial materials libraries.
Download or read book Dynamic Combinatorial Chemistry written by Benjamin L. Miller and published by John Wiley & Sons. This book was released on 2009-12-30 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Effective techniques for applying Dynamic Combinatorial Chemistry In a relatively short period, Dynamic Combinatorial Chemistry (DCC) has grown from proof-of-concept experiments in a few isolated labs to a broad conceptual framework with applications to an exceptional range of problems in molecular recognition, lead compound identification, catalyst design, nanotechnology, polymer science, and others. Bringing together a group of respected experts, this overview explains how chemists can apply DCC and fragment-based library methods to lead generation for drug discovery and molecular recognition in bioorganic chemistry and materials science. Chapters cover: Basic theory Approaches to binding in proteins and nucleic acids Molecular recognition Self-sorting Catalyst discovery Materials discovery Analytical chemistry challenges A comprehensive, single-source reference about DCC methods and applications including aspects of fragment-based drug discovery, this is a core reference that will spark the development of new solutions and strategies for chemists building structure libraries and designing compounds and materials.
Download or read book Combinatorial and High Throughput Discovery and Optimization of Catalysts and Materials written by Radislav A. Potyrailo and published by CRC Press. This book was released on 2006-07-19 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of parallel synthesis and high-throughput characterization tools offer scientists a time-efficient and cost-effective solution for accelerating traditional synthesis processes and developing the structure-property relationships of multiple materials under variable conditions. Written by renowned contributors to the field, Combina
Download or read book Handbook of Combinatorial Chemistry written by K. C. Nicolaou and published by Wiley-VCH. This book was released on 2002-04-29 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: In two volumes, this comprehensive handbook provides coverage of the whole area of combinatorial synthetic chemistry, including compound library design and synthesis.
Download or read book Materials Science and Engineering written by Radislav Potyrailo and published by Elsevier Inc. Chapters. This book was released on 2013-07-10 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sensing materials play a critical role in advancing selectivity, response speed, and sensitivity of gas determinations with sensors. The desirable capabilities of sensing materials originate from their numerous functional parameters, which can be tailored to meet specific sensing needs. By increasing the structural and functional complexity of sensing materials, the ability to rationally define the precise requirements that will result in desired materials properties becomes increasingly limited. Combinatorial experimentation methodologies impact all areas of sensing materials research. This chapter demonstrates the broad applicability of combinatorial technologies in discovery and optimization of new sensing materials for gas detection. We discuss general principles of combinatorial materials screening, followed by the discussion of the opportunities facilitated by combinatorial technologies for discovery and optimization of new sensing materials. We further critically analyze results of sensing materials development using discrete and gradient materials arrays. The emphasis of this chapter is on the analysis of results focused on the improvements of sensor selectivity and long-term stability of sensing materials. Examples from a wide variety of sensors based on various energy-transduction principles that involve radiant, mechanical, and electrical types of energy demonstrate the impact of combinatorial methodologies across diverse kinds of sensing materials.
Download or read book Materials Science and Engineering written by James N. Cawse and published by Elsevier Inc. Chapters. This book was released on 2013-07-10 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design of combinatorial and high-throughput experiments has continued to build on the progress of the last two decades. New variations of factorial and mixture designs have expanded their capability. Increasing attention is being paid to adapting designs to the constraints of the physical apparatus, in the form of split-plot methods or conscious understanding of the statistical penalties to be paid. Rapidly increasing computer power has allowed the use of more sophisticated algorithmic designs and evolutionary methods. Finally, descriptor-based design and analysis of data is making steady progress and there are hopes of its reaching a mature state in the coming decade.
Download or read book Combinatorial Geometry written by János Pach and published by John Wiley & Sons. This book was released on 2011-10-18 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete, self-contained introduction to a powerful and resurgingmathematical discipline . Combinatorial Geometry presents andexplains with complete proofs some of the most important resultsand methods of this relatively young mathematical discipline,started by Minkowski, Fejes Toth, Rogers, and Erd???s. Nearly halfthe results presented in this book were discovered over the pasttwenty years, and most have never before appeared in any monograph.Combinatorial Geometry will be of particular interest tomathematicians, computer scientists, physicists, and materialsscientists interested in computational geometry, robotics, sceneanalysis, and computer-aided design. It is also a superb textbook,complete with end-of-chapter problems and hints to their solutionsthat help students clarify their understanding and test theirmastery of the material. Topics covered include: * Geometric number theory * Packing and covering with congruent convex disks * Extremal graph and hypergraph theory * Distribution of distances among finitely many points * Epsilon-nets and Vapnik--Chervonenkis dimension * Geometric graph theory * Geometric discrepancy theory * And much more
Download or read book Materials Research to Meet 21st Century Defense Needs written by National Research Council and published by National Academies Press. This book was released on 2003-03-25 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: In order to achieve the revolutionary new defense capabilities offered by materials science and engineering, innovative management to reduce the risks associated with translating research results will be needed along with the R&D. While payoff is expected to be high from the promising areas of materials research, many of the benefits are likely to be evolutionary. Nevertheless, failure to invest in more speculative areas of research could lead to undesired technological surprises. Basic research in physics, chemistry, biology, and materials science will provide the seeds for potentially revolutionary technologies later in the 21st century.
Download or read book Combinatorial and High throughput Methods in Materials Science written by J. B. Miller and published by . This book was released on 2012 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Combinatorial and Artificial Intelligence Methods in Materials Science written by and published by . This book was released on 2003 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Electron Backscatter Diffraction in Materials Science written by Adam J. Schwartz and published by Springer Science & Business Media. This book was released on 2010-03-11 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electron backscatter diffraction is a very powerful and relatively new materials characterization technique aimed at the determination of crystallographic texture, grain boundary character distributions, lattice strain, phase identification, and much more. The purpose of this book is to provide the fundamental basis for electron backscatter diffraction in materials science, the current state of both hardware and software, and illustrative examples of the applications of electron backscatter diffraction to a wide-range of materials including undeformed and deformed metals and alloys, ceramics, and superconductors. The text has been substantially revised from the first edition, and the authors have kept the format as close as possible to the first edition text. The new developments covered in this book include a more comphrensive coverage of the fundamentals not covered in the first edition or other books in the field, the advances in hardware and software since the first edition was published, and current examples of application of electron backscatter diffraction to solve challenging problems in materials science and condensed-matter physics.
Download or read book Combinatorial Library written by Lisa B. English and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: The continued successes of large- and small-scale genome sequencing projects are increasing the number of genomic targets available for drug d- covery at an exponential rate. In addition, a better understanding of molecular mechanisms—such as apoptosis, signal transduction, telomere control of ch- mosomes, cytoskeletal development, modulation of stress-related proteins, and cell surface display of antigens by the major histocompatibility complex m- ecules—has improved the probability of identifying the most promising genomic targets to counteract disease. As a result, developing and optimizing lead candidates for these targets and rapidly moving them into clinical trials is now a critical juncture in pharmaceutical research. Recent advances in com- natorial library synthesis, purification, and analysis techniques are not only increasing the numbers of compounds that can be tested against each specific genomic target, but are also speeding and improving the overall processes of lead discovery and optimization. There are two main approaches to combinatorial library production: p- allel chemical synthesis and split-and-mix chemical synthesis. These approaches can utilize solid- or solution-based synthetic methods, alone or in combination, although the majority of combinatorial library synthesis is still done on solid support. In a parallel synthesis, all the products are assembled separately in their own reaction vessels or microtiter plates. The array of rows and columns enables researchers to organize the building blocks to be c- bined, and provides an easy way to identify compounds in a particular well.
Download or read book Combinatorial Methods and Informatics in Materials Science Volume 894 written by M. J. Fasolka and published by . This book was released on 2006-05-17 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combinatorial and high-throughput experimental approaches and related informatics, modeling and data-mining methods have permitted researchers to accelerate the pace at which new, complex materials and device systems are discovered, optimized and understood. Today, the development and application of these revolutionary approaches continue to grow and diversify. This book offers an international, interdisciplinary perspective for scientists and engineers interested in combinatorial, high-throughput and advanced informatics approaches to materials research. The range of disciplines includes materials science; chemistry; physics; electrical, chemical and mechanical engineering; materials modeling; and data systems engineering. Presentations share successful studies, and illuminate current and emerging challenges in areas including: the design and fabrication of combinatorial libraries for materials and devices; high-throughput characterization methods for such systems; automation of instrumentation and data analysis; advanced modeling and data mining techniques for rapid materials design and properties prediction; and data system design and software for combinatorial workflows.
Download or read book Combinatorial Methods for High throughput Materials Science written by and published by Curran Associates Incorporated. This book was released on 2008 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Combinatorial and Artificial Intelligence Methods in Materials Science II Volume 804 written by Radislav A. Potyrailo and published by . This book was released on 2004-03-22 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: The MRS Symposium Proceeding series is an internationally recognised reference suitable for researchers and practitioners.
