Download or read book Cold Atmospheric Plasmas Their Use In Biology And Medicine written by Spencer P Kuo and published by World Scientific. This book was released on 2019-01-25 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cold atmospheric plasma (CAP) generators have been actively developed as a new device for medical treatment. The applications of plasma treatment include 1) disinfection, sterilization, and decontamination, which inactivates or kills bacteria, fungi, viruses and spores; 2) bleeding control, which coagulates blood swiftly; 3) wound healing, which shortens the healing period and benefits the regeneration of the epithelization of tissue to avoid scar formation; etc.Biomedical applications of CAPs are explored via either in-vitro assays, or in-vivo tests using pigs as animal models; tests include sterilization of oral pathogens and biofilm, decontamination of biological warfare agent, blood clotting and rapid control of active life-threatening hemorrhage, and post-operative observation of wound healing after plasma treatment. The conventional approaches in each application are first introduced, then the advantages of plasma treatments are discussed and demonstrated by the test results. The mechanisms of CAPs' biocidal effect, blood clotting effect, and wound healing effect are presented and discussed.
Download or read book Cold Plasma written by MDPI and published by MDPI. This book was released on 2021-01-20 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-equilibrium plasma (or low-temperature plasma, LTP) offers a chemically rich medium without the need for high power and elevated temperatures. This unique characteristic has made LTP very useful for various industrial and biomedical applications where thermal effects are not desirable. In addition, the relative simplicity of the design of sources capable of generating non-equilibrium plasma at atmospheric pressure makes LTP a very attractive technology that can accomplish the same or better results than much more complex and expensive approaches. This book describes various low-temperature plasma sources and some of their environmental and biomedical applications. The plasma sources covered in this book include low-temperature plasma jets which are novel devices that can launch low-power, low-temperature plasma plumes in ambient air. These plasma plumes can accurately and reliably be aimed at a surface to be treated or at a biological target such as cells and tissues. The application of these plasma jets in medicine, including in cancer therapy, are thoroughly discussed in this book. The contents of this book will appeal to engineers, medical experts, academics, and students who work with plasma technology.
Download or read book Plasma for Bio Decontamination Medicine and Food Security written by Zdenko Machala and published by Springer Science & Business Media. This book was released on 2012-02-03 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-thermal (cold) plasmas at atmospheric pressure have recently found many breakthrough applications in biology, medicine, and food security. Plasmas can efficiently kill bacteria, yeasts, moulds, spores, biofilms and other hazardous microorganisms, including potential bio-terrorism agents. They can be employed for bio-decontamination and sterilization of surfaces, medical instruments, water, air, food, even of living tissues without causing their damage. Direct or indirect plasma interaction with living cells of microorganisms or even humans enables novel bio-medical applications, e.g. treatment of skin diseases and ulcers. Plasma-enhanced blood coagulation coupled with its antiseptic properties proved success in wound healing and opens new possibilities in surgery, emergency medicine and military applications. Plasma treatment allows cell manipulations, their removal and targeted transfer into the injured area, which can accelerate wound healing. Plasma induced apoptosis (programmed cell death) of tumor cells brings forth a great potential for cancer treatment. Besides, plasma enables painless treatment of dental caries, root canal disinfection, and other dentistry applications. This book is a selection of reviewed manuscripts issuing from the NATO Advanced Research Workshop Plasma for bio-decontamination, medicine and food security held in Jasná, Slovakia, on 15-18 March 2011. It provides a comprehensive overview of the current knowledge and research activities focused at the plasma applications in areas such as bio-decontamination, water chemistry, effects on cells; biofilm inactivation, UV sterilization, and medicine, especially tissue treatment and wound healing, as well as dentistry and food security.
Download or read book Plasma Medicine written by Alexander Fridman and published by John Wiley & Sons. This book was released on 2012-12-19 with total page 629 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive text is suitable for researchers and graduate students of a ‘hot’ new topic in medical physics. Written by the world’s leading experts, this book aims to present recent developments in plasma medicine, both technological and scientific, reviewed in a fashion accessible to the highly interdisciplinary audience consisting of doctors, physicists, biologists, chemists and other scientists, university students and professors, engineers and medical practitioners. The book focuses on major topics and covers the physics required to develop novel plasma discharges relevant for medical applications, the medicine to apply the technology not only in-vitro but also in-vivo testing and the biology to understand complicated bio-chemical processes involved in plasma interaction with living tissues.
Download or read book Plasma Medicine written by M. Laroussi and published by Cambridge University Press. This book was released on 2012-05-24 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book dedicated exclusively to plasma medicine for graduate students and researchers in physics, engineering, biology, medicine and biochemistry.
Download or read book Plasma Technology for Biomedical Applications written by Emilio Martines and published by MDPI. This book was released on 2020-05-29 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing interest in the use of physical plasmas (ionized gases) for biomedical applications, especially in the framework of so-called “plasma medicine”, which exploits the action of low-power, atmospheric pressure plasmas for therapeutic purposes. Such plasmas are “cold plasmas”, in the sense that only electrons have a high temperature, whereas ions and the neutral gas particles are at or near room temperature. As a consequence, the “plasma flame” can be directly applied to living matter without appreciable thermal load. Reactive chemical species, charged particles, visible and UV radiation, and electric fields are interaction channels of the plasma with pathogens, cells, and tissues, which can trigger a variety of different responses. Possible applications include disinfection, wound healing, cancer treatment, non-thermal blood coagulation, just to mention some. The understanding of the mechanisms of plasma action on living matter requires a strongly interdisciplinary approach, with competencies ranging from plasma physics and technology to chemistry, to biology and finally to medicine. This book is a collection of work that explores recent advances in this field.
Download or read book Plasma Medicine written by Yusuf Tutar and published by BoD – Books on Demand. This book was released on 2018-05-16 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasma can be defined as the extracellular matrix of blood cells. Plasma components, their role in human health risk evaluation, and their functional and clinical analyses are covered in this book. Furthermore, physical plasma-ionized gas is one of the four fundamental states of matter. This homonym has begun to emerge because it can interact with living systems. The physical plasma biomedical applications are reviewed in drug delivery and wound healing medical applications. This approach revolutionizes the therapeutic approaches in medicine and may open up new concepts and clinical applications. The book is an essential source for researchers in the field and provides a platform for different professions.
Download or read book Biomedical Applications of the Cold Atmospheric Plasma written by Olga Volotskova and published by . This book was released on 2015 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current breakthrough research on cold atmospheric plasma (CAP) demonstrates that CAP has great potential in various areas, including medicine and biology, thus providing a new tool for living tissue treatment. Depending on the configuration the cold plasma sources can be used in the following areas: wound healing, skin diseases, hospital hygiene, sterilization, antifungal treatments, dental care, cosmetics targeted cell/tissue removal, and cancer treatments. This dissertation is focused on the studies of biomedical applications of cold atmospheric plasma jet based on helium flow and resultant cell responses to the cold plasma treatment. The studies were carried out on extra-cellular and intra-cellular levels in vitro. The main practical applications are wound healing and alternative to existing cancer therapy methods, areas of great interest and significant challenges. The CAP jet was built in the Micropropulsion and Nanotechnology Laboratory of Dr. Michael Keidar, as a part of multidisciplinary collaboration with the GW Medical School (Dr. M.A. Stepp) concerned with plasma medicine and bioengineering studies. Normal and cancer cells have two fundamental behavioral properties, proliferation and motility, which can be evaluated through cell migration rates and cell cycle progression. Various microscopic, spectroscopic and flow cytometry techniques were used to characterize cell responses to the cold plasma treatment. It was found that CAP effect on the cells is localized within the area of the treatment (of around [approximately] 5mm in diameter). The migration rates of the normal skin cells can be reduced up to [approximately] 40%. However, depending on the cell type the required treatment time is different, thus differential treatment of various cells presented in tissue is possible. The CAP effect on the migration was explained through the changes of the cell surface proteins/integrins. It was also found that normal and cancer cells respond differently to the CAP treatment under the same experimental conditions. CAP is currently being evaluated as a new highly selective alternative addition to existing cancer therapies. It was shown that the increased sensitivity of cancer cells to CAP treatment is caused by differences in the distribution of cancer cells and normal cells within the cell cycle. It was also shown that the expression of [Upsilon]H2A.X (pSer139), an oxidative stress reporter indicating S-phase damage, is enhanced specifically within CAP treated cells in the S phase of the cell cycle together with significant decrease in EdU-signal of DNA-replicating cells. Thus, newly developed CAP technology was proven to be of a great interest for practical applications in the areas of wound healing and cancer treatment. The identification and explanation of the mechanisms by which CAP affects the cells was presented.
Download or read book Comprehensive Clinical Plasma Medicine written by Hans-Robert Metelmann and published by Springer. This book was released on 2018-05-04 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the state of the art in clinical plasma medicine and outlines translational research strategies. Written by an international group of authors, it is divided into four parts. Part I is a detailed introduction and includes basic and recent research information on plasma sciences, plasma devices and mechanisms of biological plasma effects. Parts II and III provide valuable clinical insights f.e. into the treatment of superficial contaminations, ulcerations, wounds, treatment of cells in cancer, special indications like in heart surgery, dentistry, palliative treatment in head and neck cancer or the use of plasma in hygiene. Part IV offers information on how and where to qualify in plasma medicine and which companies produce and supply medical devices and is thus of particular interest to medical practitioners. This comprehensive book offers a sciences based practical to the clinical use of plasma and includes an extended selection of scientific medical data and translational literature.
Download or read book Plasma Biosciences and Medicine written by Eun Ha Choi and published by Springer Nature. This book was released on 2023-03-25 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the updates that have been made in the field of Plasma Biosciences and Medicine over the past few years. This book provides detailed introduction and includes recent research information on plasma sources and their biological and medical applications. The opening chapters discuss plasmas physics and chemistry and plasma-activated liquids. The later part of the book discusses emerging application in medicine and biology. This book also provides valuable clinical insights into the treatment of ulcerations, wounds, cancer, dentistry, or the use of cold plasma in health and hygiene. Main target audience of this book are researchers, graduate and undergraduate students, government agencies, academicians’, engineers, biologists, medical doctor, biochemists, and industries.
Download or read book Cold Plasma Cancer Therapy written by Michael Keidar and published by Morgan & Claypool Publishers. This book was released on 2019-04-01 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cold atmospheric plasma (CAP) emerges as a possible new modality for cancer treatment. This book provides a comprehensive introduction into fundamentals of the CAP and plasma devices used in plasma medicine. An analysis of the mechanisms of plasma interaction with cancer and normal cells including description of possible mechanisms of plasma selectivity is included. Recent advances in the field, the primary challenges and future directions are presented.
Download or read book Applications of Cold Plasma in Food Safety written by Tian Ding and published by Springer Nature. This book was released on 2021-11-08 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with a comprehensive overview of cold plasma technology for tackling the various food-related hazards in a wide range of food sectors. The principles and characteristics of cold plasma generation in gas and its interaction with liquids, as well as its combating modes of action for common hazards (e.g., bacteria, spores, biofilms, fungi, and fungal toxins) are emphasized in this book. It also presents the applications of cold plasma or its hurdles with other techniques to assure the microbiological safety of the key food classifications, including fruits, vegetables, cereals, grains, meat, aquatic products, liquid food products (e.g., juices, milk), nuts, spices, herbs, and food packaging. This book is useful for researchers to grasp the comprehensive understandings of how food safety can be controlled with cold plasma technology. This book also provides adequate information for engineers in food industry for better development and optimization of the plasma-generating systems. Government institutions that are responsible for food safety regulations can understand more knowledge about the intricacies and influencing factors, which should be considered for regulating the applications of cold plasma technology in food.
Download or read book Cold Plasma in Food and Agriculture written by NN Misra and published by Academic Press. This book was released on 2016-07-15 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cold Plasma in Food and Agriculture: Fundamentals and Applications is an essential reference offering a broad perspective on a new, exciting, and growing field for the food industry. Written for researchers, industry personnel, and students interested in nonthermal food technology, this reference will lay the groundwork of plasma physics, chemistry, and technology, and their biological applications. Food scientists and food engineers interested in understanding the theory and application of nonthermal plasma for food will find this book valuable because it provides a roadmap for future developments in this emerging field. This reference is also useful for biologists, chemists, and physicists who wish to understand the fundamentals of plasma physics, chemistry, and technology and their biological interactions through applying novel plasma sources to food and other sensitive biomaterials. Examines the topic of cold plasma technology for food applications Demonstrates state-of-the-art developments in plasma technology and potential solutions to improve food safety and quality Presents a solid introduction for readers on the topics of plasma physics and chemistry that are required to understand biological applications for foods Serves as a roadmap for future developments for food scientists, food engineers, and biologists, chemists, and physicists working in this emerging field
Download or read book Redox Biology in Plasma Medicine written by Sander Bekeschus and published by CRC Press. This book was released on 2024-07-12 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasma medicine uses non-equilibrium plasmas generated under atmospheric-pressure conditions. Therapeutical plasmas can stimulate tissue regeneration or inactivate cancer cells. This book reviews the interrelation between plasma chemistry and biochemistry complemented by discussion of the ways plasmas inactivate various pathogens. Focus is on the plasma effects on mammalian cells, subsequent consequences for cell-biological processes, and plasma applicability specific medical therapies. Contributions illustrate the ways cold atmospheric-pressure plasma can be used as a controllable source of redox-active species and as a useful tool for research in redox biology. Key Features Summarizes plasma chemistry, biochemistry, and microbiology Documents the ways plasmas interact with lipids, membranes, and cells Reviews therapeutic uses of plasmas in medicine Focuses on uses of plasmas as cancer treatment
Download or read book Plasma Medical Science written by Shinya Toyokuni and published by Academic Press. This book was released on 2018-07-06 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasma Medical Science describes the progress that has been made in the field over the past five years, illustrating what readers must know to be successful. As non-thermal, atmospheric pressure plasma has been applied for a wide variety of medical fields, including wound healing, blood coagulation, and cancer therapy, this book is a timely resource on the topics discussed. Provides a dedicated reference for this emerging topic Discusses the state-of-the-art developments in plasma technology Introduces topics of plasma biophysics and biochemistry that are required to understand the application of the technology for plasma medicine Brings together diverse experience in this field in one reference text Provides a roadmap for future developments in the area
Download or read book Textbook of Good Clinical Practice in Cold Plasma Therapy written by Hans-Robert Metelmann and published by Springer Nature. This book was released on 2022-02-25 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook addresses the growing international need for a practical manual that teaches physicians how to apply cold atmospheric pressure plasma (CAP) in the day‐to‐day provision of patient healthcare. The book introduces readers to the concept of CAP, how it works, and how safe it is, before describing several diseases and other medical indications for its application. The book subsequently provides guidelines for daily clinical practice, e.g. for treating chronic wounds, decontaminating infected skin lesions, and rendering multi-resistant bacteria inert, as well as a detailed overview of plasma devices. In closing, it addresses organizational aspects, which are essential to cultivating and maintaining quality standards in the application of cold medical plasma. This textbook offers a unique educational resource and provides relevant information on plasma medicine as an emerging multidisciplinary discipline. Practitioners will appreciate this integrated, comprehensive guide, which is also suitable for advanced students of medicine and dentistry, and for nurses serving on plasma-assisted medical teams.
Download or read book Cold Atmospheric Plasmas in Medicine written by Julia L. Zimmermann and published by . This book was released on 2013 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt:
