Download or read book Clusterin written by Saverio Bettuzzi and published by Academic Press. This book was released on 2009 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. In this Part A volume, outstanding and original reviews provide an overview and synthesis of the latest thoughts and findings relating to Clusterin. Chapters include the shifiting balance between CLU Forms during tumor progression, uclear CLU and the fate of the cell, and Oxidative stress in malignant progression.
Download or read book Clusterin Part B written by and published by Academic Press. This book was released on 2009-10-26 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biological function of clusterin (CLU, also known as ApoJ, SGP2, TRPM2, CLI) has been puzzling researchers since its discovery and characterization in the early 1980s. Approaches such as cloning, expression and functional characterization of the different protein products generated by the CLU gene have now produced a critical mass of information of tremendous biological importance that are teaching us an important lesson in molecular biology of gene expression regulation. This volume brings together the contributions of top researchers in the field, providing an overview and synthesis of the latest thought and findings relating to CLU.
Download or read book Clusterin written by Judith A. K. Harmony and published by Springer. This book was released on 1995 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clusterin in Normal Brain Functions and During Neurodegeneration written by Caleb Finch and published by Landes Bioscience. This book was released on 1999 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Alzheimer s Disease Cellular and Molecular Aspects of Amyloid beta written by J. Robin Harris and published by Springer Science & Business Media. This book was released on 2004-12-17 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: To understand Alzheimer's disease (AD) is one of the major thrusts of present-day clinical research, strongly supported by more fimdamental cellular, biochemical, immunological and structural studies. It is these latter that receive attention within this book. This compilation of 20 chapters indicates the diversity of work currently in progress and summarizes the current state of knowledge. Experienced authors who are scientifically active in their fields of study have been selected as contributors to this book, in an attempt to present a reasonably complete survey of the field. Inevitably, some exciting topics for one reason or another have not been included, for which we can only apologize. Standardization of terminology is often a problem in science, not least in the Alzheimer field; editorial effort has been made to achieve standardization between the Chapters, but some minor yet acceptable personal / author variation is still present, i. e. P-amyloid/amyloid-P; Ap42/Apl-42/APi. 42! The book commences with a broad survey of the contribution that the range of available microscopical techniques has made to the study of Alzheimer's amyloid plaques and amyloid fibrillogenesis. This chapter also serves as an Introduction to the book, since several of the topics introduced here are expanded upon in later chapters. Also, it is significant to the presence of this chapter that the initial discovery of brain plaques, by Alois Alzheimer, utilized light microscopy, a technique that continues to be extremely valuable in present-day AD research.
Download or read book Clusterin in the Reproductive Tracts of Bulls and Rams and Its Relationship to Abnormal Sperm and Fertility written by Nasreldin Mohamed Ibrahim and published by . This book was released on 1998 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genetic Variants in Alzheimer s Disease written by Kevin Morgan and published by Springer Science & Business Media. This book was released on 2013-06-22 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s Disease is the most common form of dementia. The disease is characterised by the loss of synapses and neurons in the cerebral cortex and certain subcortical regions. In the last three years, the genetics of Alzheimer’s Disease has made significant advances; in fact, one could argue more than in the previous two decades. This has resulted in the identification of nine new genes and perhaps more importantly the realization that new pathways could be involved in the pathogenesis of Alzheimer’s. These new pathways are now legitimate targets for therapeutic intervention, which can possibly lead to treatment or a possible cure. The aim of this book is to put all of the recent genetic data on these new genes into context. Different genetic variants will be discussed, as well as biomarkers and future possibilities.
Download or read book Update on Dementia written by Davide Moretti and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "The dementia challenge is the largest health effort of the times we live in. The whole society has to move to a realization of the significance of prioritization to make an attempt in the direction of mental health promotion and dementia risk reduction. New priorities for research are needed to go far beyond the usual goal of constructing a disease course-modifying medication. Moreover, a full empowerment and engagement of men and women living with dementia and their caregivers, overcoming stigma and discrimination should be promoted. The common efforts and the final aim will have to be the progress of a ''dementia-constructive'' world, where people with dementia can take advantage of equal opportunities."--Provided by publisher
Download or read book Algorithms for Fuzzy Clustering written by Sadaaki Miyamoto and published by Springer Science & Business Media. This book was released on 2008-04-15 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently many researchers are working on cluster analysis as a main tool for exploratory data analysis and data mining. A notable feature is that specialists in di?erent ?elds of sciences are considering the tool of data clustering to be useful. A major reason is that clustering algorithms and software are ?exible in thesensethatdi?erentmathematicalframeworksareemployedinthealgorithms and a user can select a suitable method according to his application. Moreover clusteringalgorithmshavedi?erentoutputsrangingfromtheolddendrogramsof agglomerativeclustering to more recent self-organizingmaps. Thus, a researcher or user can choose an appropriate output suited to his purpose,which is another ?exibility of the methods of clustering. An old and still most popular method is the K-means which use K cluster centers. A group of data is gathered around a cluster center and thus forms a cluster. The main subject of this book is the fuzzy c-means proposed by Dunn and Bezdek and their variations including recent studies. A main reasonwhy we concentrate on fuzzy c-means is that most methodology and application studies infuzzy clusteringusefuzzy c-means,andfuzzy c-meansshouldbe consideredto beamajortechniqueofclusteringingeneral,regardlesswhetheroneisinterested in fuzzy methods or not. Moreover recent advances in clustering techniques are rapid and we requirea new textbook that includes recent algorithms.We should also note that several books have recently been published but the contents do not include some methods studied herein.
Download or read book Genomics Circuits and Pathways in Clinical Neuropsychiatry written by Thomas Lehner and published by Academic Press. This book was released on 2016-06-07 with total page 798 pages. Available in PDF, EPUB and Kindle. Book excerpt: This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders. - Provides interdisciplinary appeal in psychiatry, neurology, neuroscience, and genetics - Identifies key concepts, methods, and findings - Includes coverage of multiple disorders from autism to schizophrenia - Reviews specific genes associated with disorders - Discusses the genetic architecture of these syndromes - Explains how recent findings are influencing the understanding of biology - Clarifies the promise of these findings for future treatment
Download or read book Proceedings of the National Academy of Sciences of the United States of America written by National Academy of Sciences (U.S.). and published by . This book was released on 2007 with total page 1172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Journal of Rheumatology written by and published by . This book was released on 1999 with total page 1152 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Journal of Cell Science written by and published by . This book was released on 2003 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pathology and Genetics of Head and Neck Tumours written by World Health Organization and published by IARC. This book was released on 2005 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise reference book provides an international standard for pathologists and oncologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all WHO-recognized neoplasms and their variants include new ICD-O codes, incidence, age and sex distribution, location, clinical signs and symptoms, pathology, genetics, and predictive factors. This volume covers tumours of the nasal cavity and paranasal sinuses, of the nasopharynx, of the hypophyranyx, larynx and trachea, of the oral cavity and oropharynx, of salivary glands, as well as odontogenetic tumours, tumours of the ear, the paraganglionic system, and inherited tumour syndromes. Each entity is extensively discussed with information on clinicopathological, epidemiological, immunophenotypic and genetic aspects of these diseases.
Download or read book Biochemistry and Cell Biology written by and published by . This book was released on 1994 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book International Symposium sic on Gonadal Proteins and Peptides and Their Biological Significance written by M. R. Sairam and published by . This book was released on 1984 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Prostate written by and published by . This book was released on 2000 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
