Download or read book Next Generation Sequencing Data Analysis written by Xinkun Wang and published by CRC Press. This book was released on 2016-04-06 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Practical Guide to the Highly Dynamic Area of Massively Parallel SequencingThe development of genome and transcriptome sequencing technologies has led to a paradigm shift in life science research and disease diagnosis and prevention. Scientists are now able to see how human diseases and phenotypic changes are connected to DNA mutation, polymorphi

Download or read book Computational Methods for Next Generation Sequencing Data Analysis written by Ion Mandoiu and published by John Wiley & Sons. This book was released on 2016-10-03 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces readers to core algorithmic techniques for next-generation sequencing (NGS) data analysis and discusses a wide range of computational techniques and applications This book provides an in-depth survey of some of the recent developments in NGS and discusses mathematical and computational challenges in various application areas of NGS technologies. The 18 chapters featured in this book have been authored by bioinformatics experts and represent the latest work in leading labs actively contributing to the fast-growing field of NGS. The book is divided into four parts: Part I focuses on computing and experimental infrastructure for NGS analysis, including chapters on cloud computing, modular pipelines for metabolic pathway reconstruction, pooling strategies for massive viral sequencing, and high-fidelity sequencing protocols. Part II concentrates on analysis of DNA sequencing data, covering the classic scaffolding problem, detection of genomic variants, including insertions and deletions, and analysis of DNA methylation sequencing data. Part III is devoted to analysis of RNA-seq data. This part discusses algorithms and compares software tools for transcriptome assembly along with methods for detection of alternative splicing and tools for transcriptome quantification and differential expression analysis. Part IV explores computational tools for NGS applications in microbiomics, including a discussion on error correction of NGS reads from viral populations, methods for viral quasispecies reconstruction, and a survey of state-of-the-art methods and future trends in microbiome analysis. Computational Methods for Next Generation Sequencing Data Analysis: Reviews computational techniques such as new combinatorial optimization methods, data structures, high performance computing, machine learning, and inference algorithms Discusses the mathematical and computational challenges in NGS technologies Covers NGS error correction, de novo genome transcriptome assembly, variant detection from NGS reads, and more This text is a reference for biomedical professionals interested in expanding their knowledge of computational techniques for NGS data analysis. The book is also useful for graduate and post-graduate students in bioinformatics.

Download or read book Next Generation Sequencing Data Analysis written by Xinkun Wang and published by CRC Press. This book was released on 2023-07-06 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA-seq: both bulk and single-cell (separate chapters) Genotyping and variant discovery through whole genome/exome sequencing Clinical sequencing and detection of actionable variants De novo genome assembly ChIP-seq to map protein-DNA interactions Epigenomics through DNA methylation sequencing Metagenome sequencing for microbiome analysis

Download or read book Deep Sequencing Data Analysis written by Noam Shomron and published by Humana Press. This book was released on 2013-07-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new genetic revolution is fuelled by Deep Sequencing (or Next Generation Sequencing) apparatuses which, in essence, read billions of nucleotides per reaction. Effectively, when carefully planned, any experimental question which can be translated into reading nucleic acids can be applied.In Deep Sequencing Data Analysis, expert researchers in the field detail methods which are now commonly used to study the multi-facet deep sequencing data field. These included techniques for compressing of data generated, Chromatin Immunoprecipitation (ChIP-seq), and various approaches for the identification of sequence variants. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of necessary materials and reagents, step-by-step, readily reproducible protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Deep Sequencing Data Analysis seeks to aid scientists in the further understanding of key data analysis procedures for deep sequencing data interpretation.

Download or read book Cloud Computing written by Jaydip Sen and published by BoD – Books on Demand. This book was released on 2017-06-14 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the era of Internet of Things and with the explosive worldwide growth of electronic data volume, and associated need of processing, analysis, and storage of such humongous volume of data, it has now become mandatory to exploit the power of massively parallel architecture for fast computation. Cloud computing provides a cheap source of such computing framework for large volume of data for real-time applications. It is, therefore, not surprising to see that cloud computing has become a buzzword in the computing fraternity over the last decade. This book presents some critical applications in cloud frameworks along with some innovation design of algorithms and architecture for deployment in cloud environment. It is a valuable source of knowledge for researchers, engineers, practitioners, and graduate and doctoral students working in the field of cloud computing. It will also be useful for faculty members of graduate schools and universities.

Download or read book Fog Computing written by Assad Abbas and published by John Wiley & Sons. This book was released on 2020-04-21 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summarizes the current state and upcoming trends within the area of fog computing Written by some of the leading experts in the field, Fog Computing: Theory and Practice focuses on the technological aspects of employing fog computing in various application domains, such as smart healthcare, industrial process control and improvement, smart cities, and virtual learning environments. In addition, the Machine-to-Machine (M2M) communication methods for fog computing environments are covered in depth. Presented in two parts—Fog Computing Systems and Architectures, and Fog Computing Techniques and Application—this book covers such important topics as energy efficiency and Quality of Service (QoS) issues, reliability and fault tolerance, load balancing, and scheduling in fog computing systems. It also devotes special attention to emerging trends and the industry needs associated with utilizing the mobile edge computing, Internet of Things (IoT), resource and pricing estimation, and virtualization in the fog environments. Includes chapters on deep learning, mobile edge computing, smart grid, and intelligent transportation systems beyond the theoretical and foundational concepts Explores real-time traffic surveillance from video streams and interoperability of fog computing architectures Presents the latest research on data quality in the IoT, privacy, security, and trust issues in fog computing Fog Computing: Theory and Practice provides a platform for researchers, practitioners, and graduate students from computer science, computer engineering, and various other disciplines to gain a deep understanding of fog computing.

Download or read book Clinical Applications for Next Generation Sequencing written by Urszula Demkow and published by Academic Press. This book was released on 2015-09-10 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Applications for Next Generation Sequencing provides readers with an outstanding postgraduate resource to learn about the translational use of NGS in clinical environments. Rooted in both medical genetics and clinical medicine, the book fills the gap between state-of-the-art technology and evidence-based practice, providing an educational opportunity for users to advance patient care by transferring NGS to the needs of real-world patients. The book builds an interface between genetic laboratory staff and clinical health workers to not only improve communication, but also strengthen cooperation. Users will find valuable tactics they can use to build a systematic framework for understanding the role of NGS testing in both common and rare diseases and conditions, from prenatal care, like chromosomal abnormalities, up to advanced age problems like dementia. - Fills the gap between state-of-the-art technology and evidence-based practice - Provides an educational opportunity which advances patient care through the transfer of NGS to real-world patient assessment - Promotes a practical tool that clinicians can apply directly to patient care - Includes a systematic framework for understanding the role of NGS testing in many common and rare diseases - Presents evidence regarding the important role of NGS in current diagnostic strategies

Download or read book Genomics in the Cloud written by Geraldine A. Van der Auwera and published by O'Reilly Media. This book was released on 2020-04-02 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data in the genomics field is booming. In just a few years, organizations such as the National Institutes of Health (NIH) will host 50+ petabytesâ??or over 50 million gigabytesâ??of genomic data, and theyâ??re turning to cloud infrastructure to make that data available to the research community. How do you adapt analysis tools and protocols to access and analyze that volume of data in the cloud? With this practical book, researchers will learn how to work with genomics algorithms using open source tools including the Genome Analysis Toolkit (GATK), Docker, WDL, and Terra. Geraldine Van der Auwera, longtime custodian of the GATK user community, and Brian Oâ??Connor of the UC Santa Cruz Genomics Institute, guide you through the process. Youâ??ll learn by working with real data and genomics algorithms from the field. This book covers: Essential genomics and computing technology background Basic cloud computing operations Getting started with GATK, plus three major GATK Best Practices pipelines Automating analysis with scripted workflows using WDL and Cromwell Scaling up workflow execution in the cloud, including parallelization and cost optimization Interactive analysis in the cloud using Jupyter notebooks Secure collaboration and computational reproducibility using Terra

Download or read book Algorithms for Next Generation Sequencing Data written by Mourad Elloumi and published by Springer. This book was released on 2017-09-18 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 14 contributed chapters in this book survey the most recent developments in high-performance algorithms for NGS data, offering fundamental insights and technical information specifically on indexing, compression and storage; error correction; alignment; and assembly. The book will be of value to researchers, practitioners and students engaged with bioinformatics, computer science, mathematics, statistics and life sciences.

Download or read book Comprehensive Foodomics written by and published by Elsevier. This book was released on 2020-11-12 with total page 2444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Foodomics, Three Volume Set offers a definitive collection of over 150 articles that provide researchers with innovative answers to crucial questions relating to food quality, safety and its vital and complex links to our health. Topics covered include transcriptomics, proteomics, metabolomics, genomics, green foodomics, epigenetics and noncoding RNA, food safety, food bioactivity and health, food quality and traceability, data treatment and systems biology. Logically structured into 10 focused sections, each article is authored by world leading scientists who cover the whole breadth of Omics and related technologies, including the latest advances and applications. By bringing all this information together in an easily navigable reference, food scientists and nutritionists in both academia and industry will find it the perfect, modern day compendium for frequent reference. List of sections and Section Editors: Genomics - Olivia McAuliffe, Dept of Food Biosciences, Moorepark, Fermoy, Co. Cork, Ireland Epigenetics & Noncoding RNA - Juan Cui, Department of Computer Science & Engineering, University of Nebraska-Lincoln, Lincoln, NE Transcriptomics - Robert Henry, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St Lucia, Australia Proteomics - Jens Brockmeyer, Institute of Biochemistry and Technical Biochemistry, University Stuttgart, Germany Metabolomics - Philippe Schmitt-Kopplin, Research Unit Analytical BioGeoChemistry, Neuherberg, Germany Omics data treatment, System Biology and Foodomics - Carlos Leon Canseco, Visiting Professor, Biomedical Engineering, Universidad Carlos III de Madrid Green Foodomics - Elena Ibanez, Foodomics Lab, CIAL, CSIC, Madrid, Spain Food safety and Foodomics - Djuro Josic, Professor Medicine (Research) Warren Alpert Medical School, Brown University, Providence, RI, USA & Sandra Kraljevic Pavelic, University of Rijeka, Department of Biotechnology, Rijeka, Croatia Food Quality, Traceability and Foodomics - Daniel Cozzolino, Centre for Nutrition and Food Sciences, The University of Queensland, Queensland, Australia Food Bioactivity, Health and Foodomics - Miguel Herrero, Department of Bioactivity and Food Analysis, Foodomics Lab, CIAL, CSIC, Madrid, Spain Brings all relevant foodomics information together in one place, offering readers a ‘one-stop,’ comprehensive resource for access to a wealth of information Includes articles written by academics and practitioners from various fields and regions Provides an ideal resource for students, researchers and professionals who need to find relevant information quickly and easily Includes content from high quality authors from across the globe

Download or read book Applying Big Data Analytics in Bioinformatics and Medicine written by Lytras, Miltiadis D. and published by IGI Global. This book was released on 2017-06-16 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many aspects of modern life have become personalized, yet healthcare practices have been lagging behind in this trend. It is now becoming more common to use big data analysis to improve current healthcare and medicinal systems, and offer better health services to all citizens. Applying Big Data Analytics in Bioinformatics and Medicine is a comprehensive reference source that overviews the current state of medical treatments and systems and offers emerging solutions for a more personalized approach to the healthcare field. Featuring coverage on relevant topics that include smart data, proteomics, medical data storage, and drug design, this publication is an ideal resource for medical professionals, healthcare practitioners, academicians, and researchers interested in the latest trends and techniques in personalized medicine.

Download or read book Intelligent and Cloud Computing written by Debahuti Mishra and published by Springer Nature. This book was released on 2022-04-22 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book features a collection of high-quality research papers presented at the International Conference on Intelligent and Cloud Computing (ICICC 2021), held at Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, India, during October 22–23, 2021. The book includes contributions on system and network design that can support existing and future applications and services. It covers topics such as cloud computing system and network design, optimization for cloud computing, networking, and applications, green cloud system design, cloud storage design and networking, storage security, cloud system models, big data storage, intra-cloud computing, mobile cloud system design, real-time resource reporting and monitoring for cloud management, machine learning, data mining for cloud computing, data-driven methodology and architecture, and networking for machine learning systems.

Download or read book Next Generation Sequencing written by Jerzy Kulski and published by BoD – Books on Demand. This book was released on 2016-01-14 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.

Download or read book Delivery and Adoption of Cloud Computing Services in Contemporary Organizations written by Chang, Victor and published by IGI Global. This book was released on 2015-03-31 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ubiquity of technology has not only brought the need for computer knowledge to every aspect of the modern business world; it has also increased our need to safely store the data we are now creating at a rate never experienced before. Delivery and Adoption of Cloud Computing Services in Contemporary Organizations brings together the best practices for storing massive amounts of data. Highlighting ways cloud services can work effectively in production and in real time, this book is an essential reference source for professionals and academics of various disciplines, such as computer science, consulting, information technology, information and communication sciences, healthcare, and finance.

Download or read book Design and Use of Virtualization Technology in Cloud Computing written by Das, Prashanta Kumar and published by IGI Global. This book was released on 2017-08-11 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cloud computing is rapidly expanding in its applications and capabilities through various parts of society. Utilizing different types of virtualization technologies can push this branch of computing to even greater heights. Design and Use of Virtualization Technology in Cloud Computing is a crucial resource that provides in-depth discussions on the background of virtualization, and the ways it can help shape the future of cloud computing technologies. Highlighting relevant topics including grid computing, mobile computing, open source virtualization, and virtualization in education, this scholarly reference source is ideal for computer engineers, academicians, students, and researchers that are interested in learning more about how to infuse current cloud computing technologies with virtualization advancements.

Download or read book Pathology Informatics An Issue of Surgical Pathology Clinics written by Anil V. Parwani and published by Elsevier Health Sciences. This book was released on 2015-08-04 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Surgical Pathology Clinics takes a departure from its presentation of Differential Diagnosis, Histopathology, Staging, and Prognosis of tumors in different anatomic sites. This special issue is devoted to topics in pathology informatics as they relate to the practice of surgical pathology. Topics include: Basics of Information Systems (Hardware, Software); Networks, Interfaces and Communications; Databases; Data Representation, Coding and Communication Standards; Laboratory Information Systems; Enhancing and Customizing Laboratory Information Systems to Improve/Enhance Pathologist Workflow; Laboratory Management and Operations; Specialized Laboratory Information Systems; Middleware and Laboratory Automation; Synoptic Reporting in Anatomical Pathology; Bar Coding and Tracking; Molecular Pathology Informatics; Informatics and Autopsy Pathology; Pathology Informatics and Project Management; Digital Imaging Basics; Use of Digital Images in Clinical Practice; Whole Slide Imaging; Telepathology; Mobile Technologies for the Surgical Pathologist; Image Analysis; Advanced Imaging Techniques; Healthcare Information Systems; Data Security and Reliability; Role of Informatics in Patient Safety and Quality Assurance; Role of Pathology Informatics in IT Leadership; Selection and Implementation of New Information Systems; Biomedical Informatics and Research Informatics; Training in Pathology Informatics; and Building Tools for the Surgical Pathologist: Next Generation Pathologist. Editor of this issue, Dr Anil Parwani, is Professor of Pathology and Biomedical Informatics and Director of Division of Pathology Informatics. Dr. Parwani is well known as expert in the area of Anatomical Pathology Informatics, which includes design of quality assurance tools, tissue banking informatics, clinical and research data integration and mining, synoptic reporting in anatomical pathology, clinical applications of whole slide imaging, digital imaging, telepathology, image analysis and lab automation and workflow processes, such as barcoding and voice recognition.

Download or read book Next generation DNA Sequencing Informatics written by Stuart M. Brown and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Next-generation DNA sequencing (NGS) technology has revolutionized biomedical research, making complete genome sequencing an affordable and frequently used tool for a wide variety of research applications. This book provides a thorough introduction to the necessary informatics methods and tools for operating NGS instruments and analyzing NGS data"