Download or read book Clopidogrel and the Newer P2Y12 Antiplatelet Agents written by Michael P. Savage and published by . This book was released on 2019-02-22 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular disease remains the leading cause of death in the developed world. By preventing thromboembolic events such as heart attacks and strokes, antiplatelet drugs have become a cornerstone in the treatment of cardiovascular disease. Clopidogrel is a member of the thienopyridine family which inhibit ADP-induced platelet activation by irreversibly binding to the P2Y12 receptor. Clopidogrel is one of the most commonly used medications with over 9 million prescriptions written annually. It is utilized in the treatment of a wide variety of cardiovascular disorders including acute coronary syndromes (ACS), percutaneous coronary intervention (PCI) with stents, cerebrovascular disease, peripheral vascular disease, and structural heart interventions. Most often, clopidogrel is used in combination with low dose aspirin, providing dual antiplatelet therapy (DAPT). Newer, more potent P2Y12 inhibitors, prasugrel and ticagrelor, are now available as alternatives to clopidogrel. These newer agents have been shown to be more effective than clopidogrel in reducing ischemic events in patients with ACS. Recently a novel intravenous P2Y12 inhibitor, cangrelor, has become available for use during PCI in patients who have not been pretreated with an oral P2Y12 inhibitor. This book examines virtually all aspects of P2Y12 inhibitors pharmacology, clinical uses, randomized trial results, guideline recommendations, and adverse drug effects. Important fundamental issues are reviewed including comparative pharmacology of P2Y12 inhibitors, randomized trials of clopidogrel in patients with coronary artery disease, DAPT duration after PCI, and role of platelet function testing. The newer P2Y12 inhibitors (prasugrel, ticagrelor, and cangrelor) receive special focus. Use of antiplatelet therapy in specific patient populations is discussed including patients with coronary bypass graft surgery, peripheral vascular disease, cerebrovascular disease, and structural heart disease. Management of antiplatelet therapy in patients who require anticoagulation is a particularly challenging clinical setting and is the topic of a featured review. Finally, adverse drug effects and reactions are examined in a section highlighting clopidogrel resistance, clopidogrel hypersensitivity, and bleeding complications. This book is designed to provide a comprehensive review of clopidogrel and the newer P2Y12 inhibitors. Towards that end, the authors have enlisted an internationally renowned group of experts as contributors. It is intended to be a resource for clinicians, scientists, pharmacologists, and all healthcare professionals involved in the management of cardiovascular disease.

Download or read book Antiplatelet Therapy in ACS and A Fib written by Victor L. Serebruany and published by Karger Medical and Scientific Publishers. This book was released on 2012 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by top experts in the field Platelets play a critical role in the pathophysiology of acute coronary syndromes (ACS) and thromboembolic complications associated with atrial fibrillation. Anticoagulant and antiplatelet therapies are central to the treatment of ACS and atrial fibrillation. Over the last several decades, a better understanding of the pathogenesis of coronary heart disease and atrial fibrillation has led to refinements in antithrombotic strategies and clinical outcomes. With this in mind, some of the issues outlined in this book are new insights in genetic testing and modification of individualized antiplatelet therapy based on rapid bedside platelet analyzers. Most importantly, the current update of pros and cons of novel antiplatelet agents such as prasugrel and ticagrelor are provided in detail. Conventional antiplatelet strategies with aspirin and clopidogrel are also discussed. Special attention is devoted to experimental antiplatelet agents like PAR-1 thrombin receptor antagonists or aptamers. The ability to focus on different diseases beyond ACS, including heart failure and atrial fibrillation, distinguishes this publication. Each chapter was written by top experts in the field and scientists with the utmost authority and expertise to provide cardiologists, internists, and clinical pharmacologists with the latest updates.

Download or read book Primary Angioplasty written by Timothy J Watson and published by Springer. This book was released on 2018-07-13 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. This quick-reference handbook offers a concise and practical review of key aspects of the treatment of ST-segment elevation myocardial infarction (STEMI) in the era of primary percutaneous coronary intervention (PPCI). In the context of STEMI, PPCI is the preferred mode of emergency revascularization. Access to PPCI is rapidly increasing and is now routinely practiced in both general and specialist hospitals and there has been a recent emphasis on developing STEMI networks to enhance and expedite the referral pathway. This coupled with concurrent developments to enhance the safety and efficacy of the PPCI procedure has heralded an era where STEMI interventions are increasingly considered an important subspecialty within interventional cardiology. Written by leading cardiologists who have been instrumental in the adoption of PPCI in their respective institutions, the book provides junior and senior cardiologists alike with insightful and thought-provoking tips and tricks to enhance the success of PPCI procedures, which may in turn translate into direct improvements in outcomes. The book is also relevant for healthcare providers and emergency department physicians.

Download or read book Cardiology Secrets written by Glenn N. Levine and published by Elsevier Health Sciences. This book was released on 2014 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get quick answers to the most important clinical questions with Cardiology Secrets! Using the popular and trusted Secret Series(R) Q&A format, this easy-to-read cardiology book provides rapid access to the practical, "in-the-trenches" know-how you need to succeed both in practice, and on cardiology board and recertification exams. Get the evidence-based guidance you need to provide optimal care for your patients with cardiac heart diseases. Explore effective solutions to a full range of clinical issues including the general examination, diagnostic procedures, arrhythmias, symptoms and disease states, valvular heart disease, cardiovascular pharmacology, and other medical conditions with associated cardiac involvement. Zero in on key information with bulleted lists, mnemonics, practical tips from the leading cardiologists, and "Key Points" boxes that provide a concise overview of important board-relevant content. Review essential material efficiently with the "Top 100 Secrets in Cardiology" - perfect for last-minute study or self-assessment. Apply all the latest advances in clinical cardiology techniques, technology, and pharmacology. Access the complete text and illustrations online at Expert Consult, fully searchable.

Download or read book Practical Manual of Interventional Cardiology written by Annapoorna Kini and published by Springer. This book was released on 2014-11-26 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical handbook is based on an internal working manual developed by staff and fellows at Mount Sinai Heart Cardiovascular Catheterization Laboratory, renowned for its high-volume and low complication complex coronary procedures. The Practical Handbook of Interventional Cardiology captures the knowledge and methodological know-how from leaders in interventional cardiology, it intends to guide users in a stepwise, methodical and practical approach through various cardiac interventional procedures in order to achieve maximum patient safety and improved outcomes. From patient selection, preoperative work-up, setting up equipment to step-by-step illustrations of various procedural details and troubleshooting, this handbook captures all the details necessary to perform the simplest to the most complex cardiac interventions. The book is designed for cardiologists and trainees who desire an efficient way to review the steps of various cardiac interventional procedures and a quick, reliable reference for everyday use.

Download or read book Consultative Hemostasis and Thrombosis E Book written by Craig S. Kitchens and published by Elsevier Health Sciences. This book was released on 2013-02-20 with total page 843 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique clinical focus makes Consultative Hemostasis and Thrombosis, 3rd Edition your go-to guide for quick, practical answers on managing the full range of bleeding and clotting disorders. Emphasizing real-world problems and solutions, Dr. Craig S. Kitchens, Dr. Barbara A. Konkle, and Dr. Craig M. Kessler provide all the clinical guidance you need to make optimal decisions on behalf of your patients and promote the best possible outcomes. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Efficiently look up concise descriptions of each condition, its associated symptoms, laboratory findings, diagnosis, differential diagnosis, and treatment. Get the latest information on hot topics such as Disseminated Intravascular Coagulation, Thrombophilia, Clinical and Laboratory Assessment and Management, Thrombotic -Thrombocytopenic Purpura, and Heparin-Induced Thrombocytopenia. Apply today’s newest therapies, including those that are quickly becoming standard in this fast-changing field. Meet the needs of specific patient groups with a new chapter on Bleeding and the Management of Hemorrhagic Disorders in Pregnancy and an extensively updated chapter on Thrombosis and Cancer. Zero in on key information with a new user-friendly design, and all-new full-color format, abundant laboratory protocols, and at-a-glance tables and charts throughout.

Download or read book Pharmacology of Purine and Pyrimidine Receptors written by and published by Academic Press. This book was released on 2011-07-13 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an overview of the fast-moving field of purinergic signalling through adenosine and ATP receptors. Authors are the leading authorities in their fields Subject matter is important for understanding tissue protection Subject matter is of intense interest for new drug development

Download or read book Cardiac Intensive Care E Book written by David L. Brown and published by Elsevier Health Sciences. This book was released on 2018-07-19 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a multidisciplinary, team-oriented approach, this unique title expertly covers all the latest approaches to the assessment, diagnosis, and treatment of patients with critical cardiac illness. Led by Dr David L. Brown, a stellar team of authoritative writers guides you through cardiac pathophysiology, disease states presenting in the CICU, and state-of-the-art advanced diagnosis and therapeutic techniques. A visually appealing format, new chapters, and thorough updates ensure that you stay on the cutting edge of this rapidly advancing field. Discusses recent changes in cardiac intensive care, including new care paradigms, new mechanical support modalities, and new therapies and interventions. Contains 11 new chapters: Palliative Care, Temporary Pacemaker Insertion, Pericardiocentesis, Distributive Shock, Electrical Storm, Cardiopulmonary Cerebral Resuscitation after Cardiac Arrest, Temporary Mechanical Circulatory Support Devices, Cardiorenal Syndrome, Fulminant Myocarditis, Stress-Induced Cardiomyopathy, Diagnosis and Treatment of Unstable Supraventricular Tachycardia. Concisely yet thoroughly covers acute and severe heart failure, chronic pulmonary hypertension, life-threatening dysrhythmias, aortic dissection, and other cardiac conditions as they relate to intensive care. Explains drug therapy for key cardiac drugs, such as inotropes, vasodilators, anti-arrhythmics, diuretics, anticoagulants, and anti-platelets, and discusses important drug interactions. Ideal for all healthcare professionals involved in cardiac intensive care, including intensivists, cardiologists, cardiac surgeons, residents, fellows, cardiac nurses, respiratory therapists, physical therapists, and nutritionists.

Download or read book Platelets in Thrombotic and Non Thrombotic Disorders written by Paolo Gresele and published by Springer. This book was released on 2017-03-08 with total page 1445 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.

Download or read book Interventional Cardiology written by George D. Dangas and published by John Wiley & Sons. This book was released on 2016-11-28 with total page 2479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expert guidance from internationally recognized authorities, who provide clear and current updates on all aspects of interventional cardiology. This new edition; Contains a radically expanded chapter contents list presented in four clear sections; coronary interventions, interventional pharmacology, structural heart interventions, and endovascular therapy Includes 46 new chapters, including the latest advances in bioresorbable coronary stents, advanced transcatheter aortic valve replacement, MitraClip, new transcatheter mitral valve interventions, and more Chapters are templated for rapid referral, beginning with pathophysiological background and relevant pathology, moving to mechanisms of treatment, device description, procedural techniques, follow-up care, and ending with risks, contraindications and complications Multiple choice questions at the end of each chapter for self-assessment, a total of more than 400 MCQs in the book Features 19 procedural videos, hosted on a companion website

Download or read book Anesthetic Pharmacology written by Alex S. Evers and published by Cambridge University Press. This book was released on 2011-03-10 with total page 2902 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Download or read book Management of Cerebrovascular Disorders written by Alejandro M. Spiotta and published by Springer. This book was released on 2019-03-06 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important title brings together a distinguished panel of thought-leaders, known for their insights into the development and application of minimally-invasive surgical and endovascular techniques, to provide a comprehensive and discerning compendium of our most current knowledge and state-of-the-art procedures in the management of cerebral vascular diseases. Written in a style that is accessible to students and experienced practitioners alike, the book covers all the important recent advances that have reshaped the field in dramatic ways. Emphasizing how surgical and endovascular techniques are complementary, the volume includes illuminating chapters on the nexus of endovascular and conventional “open” cerebrovascular surgery, including patient assessment and practice in a hybrid operating environment, utilizing the best methods to achieve optimal outcomes. A major addition to the clinical literature, Management of Cerebrovascular Disorders: A Comprehensive, Multidisciplinary Approach will be of significant interest to neurosurgeons, neurologists, neuroradiologists, neurointensivists, students, residents, fellows, and specialized attending physicians.

Download or read book The ESC Textbook of Intensive and Acute Cardiovascular Care written by Marco Tubaro and published by Oxford University Press. This book was released on 2021-03-08 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ESC Textbook of Intensive and Acute Cardiovascular Care is the official textbook of the Acute Cardiovascular Care Association (ACVC) of the ESC. Cardiovascular diseases (CVDs) are a major cause of premature death worldwide and a cause of loss of disability-adjusted life years. For most types of CVD early diagnosis and intervention are independent drivers of patient outcome. Clinicians must be properly trained and centres appropriately equipped in order to deal with these critically ill cardiac patients. This new updated edition of the textbook continues to comprehensively approach all the different issues relating to intensive and acute cardiovascular care and addresses all those involved in intensive and acute cardiac care, not only cardiologists but also critical care specialists, emergency physicians and healthcare professionals. The chapters cover the various acute cardiovascular diseases that need high quality intensive treatment as well as organisational issues, cooperation among professionals, and interaction with other specialities in medicine. SECTION 1 focusses on the definition, structure, organisation and function of ICCU's, ethical issues and quality of care. SECTION 2 addresses the pre-hospital and immediate in-hospital (ED) emergency cardiac care. SECTIONS 3-5 discuss patient monitoring, diagnosis and specific procedures. Acute coronary syndromes (ACS), acute decompensated heart failure (ADHF), and serious arrhythmias form SECTIONS 6-8. The main other cardiovascular acute conditions are grouped in SECTION 9. Finally SECTION 10 is dedicated to the many concomitant acute non-cardiovascular conditions that contribute to the patients' case mix in ICCU. This edition includes new chapters such as low cardiac output states and cardiogenic shock, and pacemaker and ICDs: troubleshooting and chapters have been extensively revised. Purchasers of the print edition will also receive an access code to access the online version of the textbook which includes additional figures, tables, and videos to better to better illustrate diagnostic and therapeutic techniques and procedures in IACC. The third edition of the ESC Textbook of Intensive and Acute Cardiovascular Care will establish a common basis of knowledge and a uniform and improved quality of care across the field.

Download or read book Side Effects of Drugs Annual written by Jeffrey K. Aronson and published by Elsevier. This book was released on 2011-08-19 with total page 715 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Side Effects of Drugs Annual was first published in 1977. It has been continually published since then, as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs. Each new Annual continues to provide clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of Adverse Drug Reactions and Interactions. An international team of specialists has contributed to the Annuals by selecting critically from each year's writing all that is truly new and informative, by critically interpreting it, and by pointing to whatever is misleading. Provides a critical yearly survey of new data and trends Includes an essay that describes the modern approach to classifying adverse drug reactions Special reviews in this Annual include, among other topics: Antipsychotic drugs and now-onset diabetes mellitus, Treating asthma during pregnancy, and MMR vaccine and autism

Download or read book Acute Stroke Management in the Era of Thrombectomy written by Edgar A. Samaniego and published by Springer. This book was released on 2019-06-22 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​This book contains a compilation of the revolution of mechanical thrombectomy (MT) in the treatment of strokes. The initial chapters summarize information about the best medical management of acute ischemic stroke, imaging modalities and patient selection for MT. The book then focuses on the nuances of MT, providing detailed information about the best approaches for anesthesia during MT, access, intra-arterial thrombolysis, recent devices and catheters and technical pitfalls of MT. A specific chapter is dedicated to MT in the venous system. This is followed by a chapter about the most common complications of MT and post-procedural care of these patients. The last chapter covers different aspects of acute stroke care and MT in the developing world. The authors of this book comprise of a multidisciplinary group of world experts in the field and were encouraged to include teaching cases to deliver a book with a practical approach. Acute Stroke Management in the Era of Thrombectomy is intended for all healthcare providers who care for patients with stroke; with special emphasis for the proceduralists who are interested in technical tips to improve outcomes and minimize complications.

Download or read book The Interventional Cardiac Catheterization Handbook E Book written by Morton J. Kern and published by Elsevier Health Sciences. This book was released on 2017-05-02 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Packed with useful information, The Interventional Cardiac Catheterization Handbook, 4th Edition, by Drs. Morton J. Kern, Michael J. Lim, and Paul Sorajja, is the perfect hands-on resource for physicians, nurses, and technicians who need to understand and perform these complex procedures. Easy-to-read text, hundreds of clear images, and narrated videos from Dr. Kern ensure that health care workers at all levels have quick access to easily accessible guidelines on procedures and patient care. Features a wealth of quick-reference tables, and more than 500 images – making this handbook a must-have reference for physicians and staff members in every cath lab. Includes a chapter dedicated to interventional pharmacology. Includes new content on correction of mitral regurgitation with Mitra ClipTM, enhanced coverage of aortic valve stenosis with TAVR, expansion of biodegradable and drug-eluting stents, enhanced descriptions of lesion assessment, chronic total occlusion intervention, and radial access approach to intervention. Covers the latest treatment of mitral valve regurgitation and mitral stenosis, new procedural enhancements for the treatment of aortic valve stenosis, and chronic total occlusion intervention technique updates.

Download or read book Patient Blood Management in Cardiac Surgery written by Christian von Heymann and published by Springer. This book was released on 2019-06-03 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a multidisciplinary approach to the maintenance of hemostasis and minimisation of blood loss in patients undergoing cardiac surgery. All aspects of patient blood management are covered that may contribute to a reduction in perioperative bleeding and transfusion requirements in cardiac surgery. This is achieved through practical cases and a theoretical background that gives a better understanding of patient hemostasis and the occurrence of bleeding complications. This book is relevant to cardiac surgeons, anesthesiologists, clinical perfusionists, hematologists and intensivists.