Download or read book Clinical Trials in Rheumatoid Arthritis and Osteoarthritis written by David M. Reid and published by Springer Science & Business Media. This book was released on 2008-03-20 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed to be a practical handbook on clinical trial management in these key therapeutic areas, 'Clinical Trials in Rheumatoid Arthritis and Osteoarthritis' is aimed at principal investigators pharmaceutical physicians and other pharmaceutical staff involved in the design, conduct and monitoring of these increasingly complex diseases. In the last several years a new classes of biologic agents have emerged and changed the treatment paradigm for patients, not only with classically defined rheumatoid arthritis, but also with other related diseases such as ankylosing spondylitis and psoriatic arthritis. Furthermore, osteoarthritis is a major disease state that is often treated by the rheumatologist, but is one where patient management programs are currently limited with a need for new therapeutic approaches. In both inflammatory and non-inflammatory arthritic conditions, clinical trials have become both large and complex due to the nature of the diseases, with ever-challenging new surrogate end-points being employed. Topics covered in this title will therefore include study design, clinical endpoints, technical issues, data collection, use of centralized medical image reading facilities and biochemical marker laboratories, as well as data analysis and future therapies. This book takes the user through the process step-by-step from start to finish, also providing a background on the regulatory guidelines, ethical implications, endpoints, and current therapies.
Download or read book Clinical Trials in Rheumatoid Arthritis and Osteoarthritis 2008 written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Modern Therapeutics in Rheumatic Diseases written by George C. Tsokos and published by Springer Science & Business Media. This book was released on 2001-11-08 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading clinicians and clinical researchers discuss in practical detail the newest treatments used in rheumatic diseases, emphasizing-without neglecting current standard treatments-those experimental therapies now undergoing clinical trials and poised for early introduction into the rheumatology armamentarium. The diseases and therapeutic regimes examined here range from rheumatoid arthritis and its treatment by gene therapy, to osteoarthritis and systemic autoimune diseases. Each chapter is organized so that the busy clinician can quickly obtain all the information needed optimal patient treatment. This includes an analysis of the pathogenic mechanisms that explain the molecular basis of the newer therapeutics, reviews of animal data and the results of clinical trials, and recommendations concerning use, side effects, and precautions.
Download or read book Clinical Trials in Rheumatology written by Ruediger Mueller and published by Springer Science & Business Media. This book was released on 2010-12-01 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: A huge number of therapeutic studies has been published in rheumatology and clinical immunology. This number grows substantially by the year. As such, it becomes increasingly difficult to keep track of this multitude of studies and the ensuing therapeutic trends. Further to this, a particular study can be referred to in a variety of ways, either as a shortened version of the title or an acronym, adding to the confusion. The book Clinical Trials in Rheumatology provides a summary of the important studies in the field for easy reference. Every study is shown with name, acronym (if in existence), authors, complete citation, study design, results, and summary. An acronym finder is supplied at the beginning of the book. This book is a valuable reference tool for rheumatologists and other clinical specialties, as well as for research scientists interested in immunomodulatory and selected other drug therapies in rheumatologic diseases.
Download or read book The Arthritis Breakthrough written by Henry Scammell and published by M Evans & Company. This book was released on 1993-01 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most important news in half a century. DSThe Midwest Book Review
Download or read book The New Arthritis Breakthrough written by Henry Scammell and published by Rowman & Littlefield. This book was released on 1998 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines the minocycline in rheumatoid arthritis clinical trials in dramatic detail.
Download or read book Arthritis Research written by Frank H. Columbus and published by Nova Publishers. This book was released on 2005 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arthritis is an inflammatory disease affecting the joints and surrounding tissues. As the disease develops it can cause severe pain and disability. The two most common types of arthritis are osteoarthritis and rheumatoid arthritis. Osteoarthritis (OA) is a painful, degenerative joint disease that often involves the hips, knees, neck, lower back, or the small joints of the hands. Treatment usually includes analgesics, topical creams, or non-steroidal anti-inflammatory medications (known as NSAIDs); appropriate exercises or physical therapy; joint splinting; or joint replacement surgery for seriously damaged larger joints, such as the knee or hip. Rheumatoid arthritis (RA) is an autoimmune inflammatory disease that usually involves the hands, wrists, elbows, shoulders, knees, feet, or ankles. This new book brings together leading research in the field.
Download or read book Integrative Rheumatology written by Randy Horwitz and published by Oxford University Press. This book was released on 2011 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume, the authors describe a rational and evidence-based approach to the integrative therapy of rheumatologic, allergic, and autoimmune disorders, integrating the principles of alternative and complementary therapies into the principles and practice of conventional medical therapy.
Download or read book Landmark Papers in Rheumatology written by Richard A. Watts and published by OUP Oxford. This book was released on 2015-06-25 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rheumatic disease is a major cause of morbidity and disability in the Western world. There have been major developments in our understanding of the causes of rheumatic disease and in their treatment during the last half-century, and there are relatively few papers which can be regarded as truly 'landmark' in their construction and subsequent findings. Part of the Landmark Papers in series, this book provides a detailed review of the seminal papers that have paved the way for breakthroughs in the clinical management of the entire spectrum of rheumatic diseases.
Download or read book Arthritis Survey of current programs written by United States. National Commission on Arthritis and Related Musculoskeletal Diseases and published by . This book was released on 1976 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Rheumatoid Arthritis written by Hechmi Toumi and published by BoD – Books on Demand. This book was released on 2022-01-19 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rheumatoid arthritis (RA) is a chronic autoimmune disease generating joint pain and damage in which inflammation plays a major role. RA joints are inflamed and stiff. Symptoms include joint swelling and warmth causing fatigue affecting life’s health-related quality. Still, there are many other medical conditions that can also be associated with your symptoms and signs. This book is not a substitute for a diagnosis from a healthcare provider. Yet, understanding your symptoms and signs and educating yourself about health conditions is important and can contribute to having the healthiest possible life. Herein, Professor Hechmi Toumi offers an edited volume with detailed new information on RA pathogenesis and explains both approaches and treatment options: recent clinical research and traditional methods.
Download or read book Management of Rheumatoid Arthritis and Osteoarthritis written by Stephen M. Krane and published by . This book was released on 1983 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Innovation in Rheumatology written by Jason Liebowitz and published by CRC Press. This book was released on 2022-10-04 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tremendous advances have been made in the field of rheumatology, profoundly changing our understanding of many rheumatologic conditions and creating a new frontier for effective treatments. This book explains the most significant advances in research and care and speculates as to what will be the future of rheumatology over the next several decades, including challenges and lessons learned from past experiences in the field. It highlights landmark research articles and scientific discoveries, discusses how big data, personalized medicine, new biomarkers for disease, and other technological revolutions will shape the future, making it a must-have resource for physicians from all regions of the world. Key Features • Includes concise yet thorough description of the landmark studies and scientific breakthroughs coupled with easy-to-follow organizational structure of chapters that are accessible to readers at different levels of training. • Brings together world-leading experts to provide a fresh perspective to trainees such as residents and fellows-in-training, as well as more senior clinicians and researchers across the field of rheumatology and in specialties such as cardiology, dermatology, pulmonology, nephrology, and neurology, all of whom care for patients with rheumatologic conditions. • Allows the authors to imagine and speculate about the evolution of the field of rheumatology in the coming decades. Examples of such speculative possibilities include use of synovial biopsy to predict response to treatment in rheumatoid arthritis, replacement of renal biopsy with urinary proteomics in diagnosing and classifying lupus nephritis, use of new therapeutics to obviate the need for steroids in the treatment of ANCA-associated vasculitis, and the use of machine learning to evaluate subtle changes in imaging for management of inflammatory arthritis.
Download or read book A Clinician s Pearls Myths in Rheumatology written by John H. Stone and published by Springer Science & Business Media. This book was released on 2009-10-03 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Important strides have been made in understanding the pathophysiologic basis of many inflammatory conditions in recent years, but rheumatology remains a discipline in which diagnosis is rooted in the medical history skillfully extracted from the patient, the careful physical examination, and the discriminating use of laboratory tests and imaging. Moreover, selection of the most appropriate therapy for patients with rheumatic diseases also remains heavily reliant upon clinical experience. Medical disciplines such as rheumatology that depend significantly upon clinical wisdom are prone to the development of systems of ‘Pearls’ and ‘Myths,’ related to the diseases they call their own, a ‘Pearl’ being a nugget of truth about the diagnosis or treatment of a particular disease that has been gained by dint of clinical experience and a ‘Myth’ being a commonly held belief that influences the practice of many clinicians – but is false. This book will pool together the clinical wisdom of seasoned, expert rheumatologists who participate in the care of patients with autoimmune diseases, systemic inflammatory disorders, and all other rheumatic conditions.
Download or read book Outcome Measures in Rheumatoid Arthritis Clinical Trials written by and published by . This book was released on 1993 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Health disparities in rheumatic diseases Part II An Issue of Rheumatic Disease Clinics of North America E Book written by Candace H Feldman and published by Elsevier Health Sciences. This book was released on 2020-11-20 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Rheumatic Disease Clinics, guest edited by Dr. Candace Feldman, is Part II of a two-part issue covering Health Disparities in Rheumatic Diseases. This issue is one of four selected each year by series Consulting Editor, Dr. Michael Weisman. Topics discussed in this issue include, but are not limited to: Disparities in Lupus Care and Outcomes among U.S. Medicaid Beneficiaries, Understanding Risk Factors for Poor Outcomes in a Multiethnic Longitudinal Cohort, Impact of Psychosocial Factors on RA and Lupus Health Disparities, Racial/ethnic and geographic disparities in knee and hip osteoarthritis, Racial/ethnic Disparities in Osteoarthritis Management, Challenges and Strategies to Achieve Equitable Rheumatologic Care Across the World, Strategies to Reduce Disparities, Understanding and Addressing the Provider Biases and the Lack of Diversity in Lupus Clinical Trials, Community-engaged Research: Lupus Conversations, Leveraging Telemedicine as an Approach to Address Rheumatic Disease Health Disparities, and Understanding the Role and Challenges of Patient Preferences in Disparities in Rheumatic Disease Care.
Download or read book Early Rheumatoid Arthritis written by Paul Emery and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue covers the latest developments in the understanding of rheumatoid arthritis at the early stage. Treatments such as with newer biologic agents and conventional disease-modifying antirheumatic drugs are reviewed. Also included are articles on imaging modalities as a means of identifying those in the early stages and monitoring response to treatment.
