Download or read book Clinical Research Design and Analysis in the Behavioral Sciences written by Eugene Elmer Levitt and published by . This book was released on 2012-03-01 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Clinical Research Design and Analysis in the Behavioral Sciences written by Eugene E Levitt and published by Hassell Street Press. This book was released on 2021-09-09 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Download or read book Clinical research design and analysis in the behavioral sciences with an introd written by Eugene Elmer Levitt and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Clinical Research Design and Analysis in the Behavior Sciences written by Eugene E. Levitt and published by . This book was released on 1961 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Clinical Research Design and Analysis in the Behavioral Sciences With an Introd by John I Nurnberger written by Eugene E. Levitt and published by . This book was released on 1961 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Small Clinical Trials written by Institute of Medicine and published by National Academies Press. This book was released on 2001-01-01 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.

Download or read book Design and Analysis of Clinical Trials written by Shein-Chung Chow and published by John Wiley & Sons. This book was released on 2008-12-04 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the First Edition of Design and Analysis of Clinical Trials "An excellent book, providing a discussion of the clinical trial process from designing the study through analyzing the data, and to regulatory requirement . . . could easily be used as a classroom text to understand the process in the new drug development area." –Statistical Methods in Medicine A complete and balanced presentation now revised, updated, and expanded As the field of research possibilities expands, the need for a working understanding of how to carry out clinical trials only increases. New developments in the theory and practice of clinical research include a growing body of literature on the subject, new technologies and methodologies, and new guidelines from the International Conference on Harmonization (ICH). Design and Analysis of Clinical Trials, Second Edition provides both a comprehensive, unified presentation of principles and methodologies for various clinical trials, and a well-balanced summary of current regulatory requirements. This unique resource bridges the gap between clinical and statistical disciplines, covering both fields in a lucid and accessible manner. Thoroughly updated from its first edition, the Second Edition of Design and Analysis of Clinical Trials features new topics such as: Clinical trials and regulations, especially those of the ICH Clinical significance, reproducibility, and generalizability Goals of clinical trials and target population New study designs and trial types Sample size determination on equivalence and noninferiority trials, as well as comparing variabilities Also, three entirely new chapters cover: Designs for cancer clinical trials Preparation and implementation of a clinical protocol Data management of a clinical trial Written with the practitioner in mind, the presentation assumes only a minimal mathematical and statistical background for its reader. Instead, the writing emphasizes real-life examples and illustrations from clinical case studies, as well as numerous references-280 of them new to the Second Edition-to the literature. Design and Analysis of Clinical Trials, Second Edition will benefit academic, pharmaceutical, medical, and regulatory scientists/researchers, statisticians, and graduate-level students in these areas by serving as a useful, thorough reference source for clinical research.

Download or read book Behavioral Clinical Trials for Chronic Diseases written by Lynda H. Powell and published by Springer Nature. This book was released on 2021-10-13 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive guide to the design of behavioral randomized clinical trials (RCT) for chronic diseases. It includes the scientific foundations for behavioral trial methods, problems that have been encountered in past behavioral trials, advances in design that have evolved, and promising trends and opportunities for the future. The value of this book lies in its potential to foster an ability to “speak the language of medicine” through the conduct of high-quality behavioral clinical trials that match the rigor commonly seen in double-blind drug trials. It is relevant for testing any treatment aimed at improving a behavioral, social, psychosocial, environmental, or policy-level risk factor for a chronic disease including, for example, obesity, sedentary behavior, adherence to treatment, psychosocial stress, food deserts, and fragmented care. Outcomes of interest are those that are of clinical significance in the treatment of chronic diseases, including standard risk factors such as cholesterol, blood pressure, and glucose, and clinical outcomes such as hospitalizations, functional limitations, excess morbidity, quality of life, and mortality. This link between behavior and chronic disease requires innovative clinical trial methods not only from the behavioral sciences but also from medicine, epidemiology, and biostatistics. This integration does not exist in any current book, or in any training program, in either the behavioral sciences or medicine.

Download or read book Clinical Research Design and Analysis in the Behaviorial Sciences Etc written by Eugene Elmer LEVITT and published by . This book was released on 1961 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook for Clinical Research written by Flora Hammond, MD and published by Demos Medical Publishing. This book was released on 2014-08-26 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: With over 80 information-packed chapters, Handbook for Clinical Research delivers the practical insights and expert tips necessary for successful research design, analysis, and implementation. Using clear language and an accessible bullet point format, the authors present the knowledge and expertise developed over time and traditionally shared from mentor to mentee and colleague to colleague. Organized for quick access to key topics and replete with practical examples, the book describes a variety of research designs and statistical methods and explains how to choose the best design for a particular project. Research implementation, including regulatory issues and grant writing, is also covered. The book opens with a section on the basics of research design, discussing the many ways in which studies can be organized, executed, and evaluated. The second section is devoted to statistics and explains how to choose the correct statistical approach and reviews the varieties of data types, descriptive and inferential statistics, methods for demonstrating associations, hypothesis testing and prediction, specialized methods, and considerations in epidemiological studies and measure construction. The third section covers implementation, including how to develop a grant application step by step, the project budget, and the nuts and bolts of the timely and successful completion of a research project and documentation of findings: procedural manuals and case report forms collecting, managing and securing data operational structure and ongoing monitoring and evaluation and ethical and regulatory concerns in research with human subjects. With a concise presentation of the essentials for successful research, the Handbook for Clinical Research is a valuable addition to the library of any student, research professional, or clinician interested in expanding the knowledge base of his or her field. Key Features: Delivers the essential elements, practical insights, and trade secrets for ensuring successful research design, analysis, and implementation Presents the nuts and bolts of statistical analysis Organized for quick access to a wealth of information Replete with practical examples of successful research designs Û from single case designs to meta-analysis - and how to achieve them Addresses research implementation including regulatory issues and grant writing "

Download or read book Principles of Research in Behavioral Science written by Bernard E. Whitley and published by Routledge. This book was released on 2013 with total page 778 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for beginning graduate or advanced undergraduate students, this book provides a comprehensive review of research methods used in psychology and related disciplines. It covers topics that are often omitted in other texts including correlational and qualitative research and integrative literature reviews. Basic principles are reviewed for those who need a refresher. The focus is on conceptual issues ¿ statistics are kept to a minimum. Featuring examples from all fields of psychology, the book addresses laboratory and field research. Chapters are written to be used independently, so instructors can pick and choose those that fit their course needs. Reorganized to parallel the steps of the research process, tips on writing reports are also provided. Each chapter features an outline, key terms, a summary, and questions and exercises that integrate chapter topics and put theory into practice. A glossary and an annotated list of readings are now included. Extensively updated throughout, the new edition features a new co-author, Mary Kite, and: ¿ New chapters on qualitative research and content analysis and another on integrative literature reviews including meta-analysis, critical techniques for today¿s research environment. ¿ A new chapter on exploratory and confirmatory factor analysis that addresses the use of path analysis and structural equation modeling. ¿ A new chapter on how to write a research report using APA style. ¿ Examples from cross-cultural and multi-cultural research, neuroscience, cognitive, and developmental psychology along with ones from social, industrial, and clinical psychology. ¿ More on Internet research and studies. ¿ Greatly expanded Part 3 on research designs with chapters on true experiments, field research, correlational and single-case designs, content analysis, and survey and qualitative research. ¿ A website with PowerPoint slides for each chapter, a test bank with short answer and multiple choice questions, additional teaching resources, and the tables and figures from the book for Instructor¿s and chapter outlines, suggested readings, and links to related web sites for students. Intended as a text for beginning graduate and/or advanced undergraduate courses in research methods or experimental methods or design taught in psychology, human development, family studies, education, or other social and behavioral sciences, a prerequisite of undergraduate statistics and a beginning research methods course is assumed.

Download or read book Single Case Research Methodology written by Jennifer R. Ledford and published by Routledge. This book was released on 2018-01-19 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Single Case Research Methodology, 3rd Edition presents a thorough, technically sound, user-friendly, and comprehensive discussion of single case research methodology. This book can serve as a detailed and complex reference tool for students, researchers, and practitioners who intend to conduct single case research design studies; interpret findings of single case design studies; or write proposals, manuscripts, or reviews of single case methodology research. The authors present a variety of single case research studies with a wide range of participants, including preschoolers, K-12 students, university students, and adults in a variety of childcare, school, clinical, and community settings, making the book relevant across multiple disciplines in social, educational, and behavioral science including special and general education; school, child, clinical, and neuropsychology; speech, occupational, recreation, and physical therapy; and social work.

Download or read book Design and Analysis of Clinical Experiments written by Joseph L. Fleiss and published by John Wiley & Sons. This book was released on 2011-01-25 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1986, this unique reference to clinical experimentation remains just as relevant today. Focusing on the principles of design and analysis of studies on human subjects, this book utilizes and integrates both modern and classical designs. Coverage is limited to experimental comparisons of treatments, or in other words, clinical studies in which treatments are assigned to subjects at random.

Download or read book Becoming a Behavioral Science Researcher Second Edition written by Rex B. Kline and published by Guilford Publications. This book was released on 2019-11-12 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Students and beginning researchers often discover that their introductory statistics and methods courses have not fully equipped them to plan and execute their own behavioral research studies. This indispensable book bridges the gap between coursework and conducting independent research. With clarity and wit, the author helps the reader build needed skills to formulate a precise, meaningful research question; understand the pros and cons of widely used research designs and analysis options; correctly interpret the outcomes of statistical tests; make informed measurement choices for a particular study; manage the practical aspects of data screening and preparation; and craft effective journal articles, oral presentations, and posters. Including annotated examples and recommended readings, most chapters feature theoretical and computer-based exercises; an answer appendix at the back of the book allows readers to check their work.

Download or read book Behavioral Intervention Research written by Laura N. Gitlin, PhD and published by Springer Publishing Company. This book was released on 2015-12-07 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: “ I applaud [this] book for providing a much needed overview of the entire “behavioral intervention pipeline.” It fills a unique niche in its coverage of key theoretical and methodological aspects as well as its case examples and professional development considerations, which makes the content accessible and practical for a broad audience.” -Marcia Ory, PhD From the Foreword This unique text provides comprehensive coverage of one of the most neglected—yet vitally important--areas of public health research: developing, evaluating, and implementing novel behavioral interventions in service and practice settings. Written for Masters- and Doctoral-level courses as well as novice and expert researchers in this area, the book examines the most critical issues surrounding this form of research in order to maximize the ability of intervention researchers to successfully implement current and future evidence-based protocols in practice settings. Expert contributors embrace key challenges —the complexities of health care delivery, disease management and prevention, rising costs, and changing population demographics—in shaping the push toward advancing more efficient and effective behavioral interventions and methodologies. Tackling numerous topics that have been neglected in traditional randomized trial handbooks, methodology texts, and books on dissemination and implementation science, the book addresses: ways to develop and advance an intervention, emerging hybrid trial designs - theories and new models for integrating behavioral interventions with implementation science - - recruitment and retention strategies for inclusion of diverse samples - research designs for different stages of intervention development - treatment fidelity models and measures - novel measurement and analytic strategies - cost analyses - selection of control groups - use of mixed methodology - ethics and informed consent - technology-based intervention approaches – professional considerations. Abundant case examples from successful behavioral intervention trials—both national and international--illustrate key concepts. Key Features: Includes examples of a wide range of interventions including individuals across the life span and of diverse communities and health systems Replete with case examples from successful behavioral intervention trials Presents the challenges of and strategies for advancing behavioral interventions for immediate use in practice Written by world-recognized expert authors and contributors Provides novel coverage of a great variety of important—but previously neglected--topics

Download or read book Research Methods in Applied Behavior Analysis written by Alan Poling and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: The branch of clinical psychology known as behavior modification or, synonymously, applied behavior analysis, has grown substantially from humble beginnings in the 1960s. Many colleges and universities now offer courses in applied behavior analysis, and more than a few grant degrees in the area. Although they remain controversial, behavior mod ification procedures have been used to good advantage in dealing with a range of problem behaviors and are now rather widely employed in schools, residential institutions, and other therapeutic facilities. The two hallmarks of applied behavior analysis are utilization of the principles of operant conditioning to improve human behavior and utilization of scientific research methodology to assess the effectiveness of treatments. The present text provides an overview of several issues peculiar to applied behavior analysis research methodology. Six general areas of concern are (a) trends in applied behavior analysis research, (b) assessment and measurement issues, (c) experimental designs and strategies, (d) interpretation of findings, (e) ethical issues in applied behavior analysis, and (f) the societal impact of studies in the area. As evidenced by a sizable number of recently published articles, these topics are of considerable interest to behavior analysts. They also are relevant for students of scientific epistemology and general psychological research methods.

Download or read book Research Methods for the Behavioral Sciences written by Gregory J. Privitera and published by SAGE Publications. This book was released on 2022-07-07 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Updated Third Edition has been fully revised for the seventh edition of the Publication Manual of the American Psychological Association (2020), both in the APA style sections within content and the references. The language within the text has been updated to be as inclusive as possible regarding all aspects of identity. The APA sections on style, paper preparation, and ethics have been updated and the text itself has been formatted in the 7th edition style to better reflect the latest style guidance. Both comprehensive and clear, Research Methods for the Behavioral Sciences, Third Edition author Gregory J. Privitera employs a problem-focused approach to introduce research methods. A conversational writing tone speaks to learners directly, empowering students to view research methods as something they are capable of understanding and applying. Within each chapter, students draw conclusions by following the scientific process. To do enable this, Privitera fully integrates the research methods decision tree—from choosing a research design to choosing an appropriate statistic—to encourage students to select the most appropriate methodology for the research question they′re seeking to answer. Greg Privitera covers the full scope of methodologies from non-experimental to quasi-experimental to experimental in a straightforward, unbiased manner.