Download or read book Clinical Interest of Steroid Hormone Receptors in Breast Cancer written by G LeClercq and published by . This book was released on 1984-03-02 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunocytochemistry for Steroid Receptors written by Louis P. Pertschuk and published by CRC Press. This book was released on 1990-08-15 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of the literature on steroid hormone receptor immuncytochemistry. It includes the development of the first monoclonal antireceptor antibody and initial procedures designed to localize steroid receptors in situ up to the present. The step-by-step instructions provide easy reading of topics such as tissue handling, processing, and interpretation. This text places particular emphasis on the studies of human material-especially mammary carcinoma. It presents specific details with chapters on estrogen and progesterone receptors in breast malignancies and benign breast disease. Each section of this outstanding book contains comprehensive photomicrographs that illustrate the most salient features discussed. Detailed graphs pertaining to theoretical particulars concerning technology and the relationship between image analysis and endocrine response are also included. This monograph is an excellent resource for all researchers concerned with hormone-dependent tissues, pathologists who have an interest in working with novel techniques for localizing steroid hormone receptors, and oncologists who must use assay results in the treatment of breast cancer.
Download or read book Localization Of Putative Steroid Receptors written by Pertschuk and published by CRC Press. This book was released on 2018-02-01 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: These volumes represent the "state-of-the-art" in morphological methods for detection of steroid receptors. Some physician authors have applied many of the new methodologies in clinical research projects deisgned to improve medical practice, and these attempts have been placed in Volume II. The Background and recent advances presented here are intended to stimulate further experimentation and new innovations, and spur clinical trials by all investigators with an interest in steroid hormones, cell biology, and clinical oncology.
Download or read book Steroid Hormone Receptors Basic and Clinical Aspects written by V. K. Moudgil and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past few years have witnessed the emergence of steroid hormones as the wonder molecules which generate as much discussion in the scientific literature as they do in a typical living room. This transition has been a result of the tremendous public and scientific interest in the normal functioning of the hor mones as well their suggested involvement in several clinical conditions. In the recent past, notable scientific and technological advances have been made in the areas of contraception and regulation of fertility. Steroid receptors are the indis pensable mediators of hormonal responses and are complex protein molecules which appear to exist in association with other, yet undefined, proteins and/or factors. Receptors for vitamin D, retinoic acid and the thyroid hormones share structural similarities with steroid receptors, and the roster of this superfamily is still expanding. While our knowledge of the diversity and magnitude of steroid effects has advanced, the precise mode of steroid hormone action has alluded investigators. This volume brings together an international team of prominent investigators who discuss their most recent work on the basic and clinical aspects of steroid/nuclear receptors. The contributions represent updated versions of the invited presentations made at The Second Meadow Brook Conference on Steroid Receptors in Health and Disease. I am grateful to my colleagues on the Scientific Committee: Etienne Baulieu, Jack Gorski, Benita Katzenellenbogen, David Toft and James WittJiff, who provided the vision and guidance in formulating an out standing program.
Download or read book Steroid Hormone Action and Cancer written by K. Menon and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is an outgrowth of a symposium held at the University of Michigan, Ann Arbor, Michigan, October 27-29, 1975. This symposium was organized to bring together basic scientists and clinicians for the purpose of exchanging new ideas and the latest information in the area of Steroid Hormone Action and Cancer. The design of the symposium included both formal plenary sessions and informal roundtable discussion groups, the chapters of this volume being drawn primarily from these proceedings. During the last quarter of a century considerable progress has been made toward understanding the molecular mechanisms in volved in steroid hormone action. It now appears that the mechan sim of action of the four major classes of steroid hormones is qualitatively similar. Research during the past decade has demonstrated steroid hormone receptors in a variety of normal and neoplastic tissues. Receptor-containing neoplasms have been shown to be hormone-dependent and undergo regression when treated with hormone antagonists. Natural and synthetic steroids also have been employed for many years to successfully treat various types of cancer, for example: estrogens, androgens and progestagens for breast cancer; estrogens and progestagens for prostatic carcinoma; progestagens for endometrial carcinoma; and corticoids for leu kemias. All of these neoplasms have now been found to possess receptors for the steroids empirically used in their treatment.
Download or read book Steroid Receptors in Health and Disease written by Virinder Moudgil and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last two decades, progress in steroid hormone research has resulted in the development of new approaches to contraception as well as diagnosis and treatment of endocrine disorders and cancers. Although significant advances have been made in the purification, characterization, immunochemistry and molecular biology of steroid receptors, the precise molecular mechanism of steroid hormone action has remained obscure. This book captures the detailed presentations made at the first conference on Steroid Receptors in Health and Disease held at Meadow Brook Hall, Oakland University in the fall of 1987. The purpose of this international con ference was to facilitate scientific exchange toward a better understand ing of the mode of action of steroid hormones. The scientific sessions consisted of poster presentations and state-of-the-art lectures, the latter of which make up this volume. The first chapter is meant to provide the reader with a more general background of the topics covered in the book, as well as to discuss certain theme-related issues that are either not yet well-established or accepted or are in the stage of infancy. It is hoped that this volume will serve as a useful treatise for students and investigators interested in basic and clinical aspects of biological regulation by steroid hormones. A task of this magnitude could not have been undertaken without the encouragement, advice and continued generous assistance of the members of the scientific committee. I am gratefully indebted to Drs.
Download or read book Steroid Receptors in Breast Cancer written by and published by . This book was released on 1983 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hormone Receptors in Breast Cancer written by Suzanne A. W. Fuqua and published by Springer Science & Business Media. This book was released on 2008-12-10 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormone Receptors in Breast Cancer provides an up-to-date resource of the role of hormone receptors in breast cancer written in depth for both the basic molecular academic researcher and translational scientist. Advances in basic science of molecular endocrinology have undoubtedly been translated into clinical practice, and clinicians caring for this disease need to be knowledgeable about these developments. The molecular basis of hormone action has been elucidated, and the relative significance of the different estrogen and progesterone receptor isoforms has been explored. This explosion of information has lead to exciting new areas of gene specific targeting of the disease, and breast cancer prevention. Paradigm shifts in treatment options and sequencing have recently occurred in breast cancer management, necessitating close cooperation and communication between translational scientists and physicians. This book is focused on providing this communication.
Download or read book Localization Of Putative Steroid Receptors written by Louis P. Pertschuk and published by CRC Press. This book was released on 2019-07-23 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: These volumes represent the "state-of-the-art" in morphological methods for detection of steroid receptors. In Volume I we have attempted to collect current available methods and experimental approahes which might be useful in solving present enigmas. The background and recent advances presented are intended to stimulate further experimentation and new innovations, and spur clinical trials by all investigators with an interest in steroid hormones, cell biology, and clinical oncology.
Download or read book Hormones and Cancer written by Wayne V. Vedeckis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series, Hormones in Health and Disease, was launched in 1993 to provide a scientific platform for investigators engaged in research on the biological actions of hormones and to anticipate relevance for their findings in clinical applications. The first volume of the series was dedicated to the discussion and understanding of molecular mechanisms by which steroid hormones influence target cells in normal and pathological conditions. With the diversity of information and the vast amount of literature on steroid hormone physiology, a more thorough treatment of Hormones and Cancer was identified as a timely topic. In this second volume in the series, Dr. Wayne V. Vedeckis has success fully undertaken the monumental task of editing the findings of the leading investigators in hormone and cancer research. Dr. Vedeckis brings to this project two decades of research experience in hormone action; he is actively engaged in elucidating hormone and cancer interrelations. It is a pleasure to welcome him to the series as an editor and congratulate him and all contribu tors in presenting this comprehensive treatise. The 20 chapters include discussions on contemporary topics relating control of cell division and signal transduction to the basic mechanisms of carcinogenesis by cloning patient genes, and recognizing the importance of steroid receptors in treatment protocols of various endocrine abnormalities.
Download or read book Clinical Interest of Steroid Hormone Receptors in Breast Cancer written by G. Leclercq and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several papers dealing with the clinical relevance of steroid hormone receptors in breast cancer have already been published. However, no publication has overviewed studies currently being conducted in Europe, nor is there a register of the european centers performing receptor assays. It has been our purpose to fill these gaps. A large majority of authors who we contacted kindly agreed to con tribute to our book. Papers were grouped into six main parts according to their contents. The abundance of clinical data relevant to receptor assays led us to add critical summaries to help the reader to form his own opinions on the subject. We would like to thank Drs. R. J. B. King, G. Contesso, L. Santi, and E. Engelsman, who helped us in this regard. We hope that this book will enable the reader to become acquainted with the present state of European steroid hormone receptor studies devoted to breast cancer treatment. We also hope that it will promote cooperation between European oncologists involved in this field of research.
Download or read book Advances in Rapid Sex Steroid Action written by Gabriella Castoria and published by Springer Science & Business Media. This book was released on 2011-12-15 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast and prostate cancers are both hormone-dependent, at least in some stages of their progression. Hormonal manipulation represents an important therapeutic approach. Although most of breast and prostate cancers initially respond to hormone therapy, most tumors reinitiate to growth. Finally, hormone-resistant and metastatic breast and prostate cancers may develop. Thus, the challenge is the dissection of mechanisms by which steroid receptor signaling pathways continue to influence cell growth and invasiveness. Compelling evidence indicates that steroid hormones elicit non-genomic responses in extra-nuclear compartment of target cells. In this cellular location, steroid-coupled receptors rapidly recruit signaling effectors or scaffold proteins and activate multiple pathways leading to proliferation, survival, migration and invasiveness. The immediate challenge is the dissection of key events regulating the steroid response of target tissues to prevent progression and improve treatment of breast and prostate cancers.
Download or read book Steroid Receptor Assays in Human Breast Tumours written by Roger John Benjamin King and published by . This book was released on 1979 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Steroid Receptors and Disease written by Peter J. Sheridan and published by . This book was released on 1988 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book IMMUNOLOGY OF STEROID HORMONE RECEPTORS written by Shanthi Raam and published by Springer. This book was released on 1988-06-30 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nuclear Hormone Receptors written by Malcolm G. Parker and published by . This book was released on 1991 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the supergene family made up of those nuclear hormone receptors which recognize thyroid and steroid hormones, vitamen D and retinoic acid and which are characterized by their ability to bind both ligands and the genes which respond to them.
Download or read book Steroid Hormone Receptors written by V. K. Moudgil and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
