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Book Clinical Applications of in Vivo Neutron activation Analysis

Download or read book Clinical Applications of in Vivo Neutron activation Analysis written by and published by . This book was released on 1982 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: In vivo neutron activation has opened a new era of both clinical diagnosis and therapy evaluation, and investigation into and modelling of body composition. The techniques are new, but it is already clear that considerable strides can be made in increasing accuracy and precision, increasing the number of elements susceptible to measurement, enhancing uniformity, and reducing the dose required for the measurement. The work presently underway will yield significant data on a variety of environmental contaminants such as Cd. Compositional studies are determining the level of vital constituents such as nitrogen and potassium in both normal subjects and in patients with a variety of metabolic disorders. Therapeutic programs can be assessed while in progress.

Book In vivo Neutron Activation Analysis

Download or read book In vivo Neutron Activation Analysis written by and published by . This book was released on 1982 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: In vivo neutron activation has opened a new era of both clinical diagnosis and therapy evaluation, and investigation into and modelling of body composition. The techniques are new, but it is already clear that considerable strides can be made in increasing accuracy and precision, increasing the number of elements susceptible to measurement, enhancing uniformity, and reducing the dose required for the measurement. The work presently underway will yield significant data on a variety of environmental contaminants such as Cd. Compositional studies are determining the level of vital constituents such as nitrogen and potassium in both normal subjects and in patients with a variety of metabolic disorders. Therapeutic programs can be assessed while in progress. It seems likely that by the end of this century there will have been significant progress with this research tool, and exciting insights obtained into the nature and dynamics of human body composition.

Book In vivo Neutron activation Analysis

Download or read book In vivo Neutron activation Analysis written by and published by . This book was released on 1982 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Medical Application of in Vivo Neutron Activation Analysis

Download or read book Medical Application of in Vivo Neutron Activation Analysis written by and published by . This book was released on 1978 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The clinical usefulness of total body neutron activation analysis (TBNAA) was clearly established at an IAEA panel meeting in Vienna in 1972. It is best demonstrated by the studies involving the measurement of total-body calcium. This measurement provides data useful for the diagnosis and management of metabolic bone disorders. It should be emphasized, however, that while most of the applications to date have involved calcium and phosphorus, the measurement of sodium, chlorine and nitrogen also appear to be useful clinically. Total-body calcium measurements utilizing TBNAA have been used in studies of osteoporosis to establish absolute and relative deficits of calcium in patients with this disease in comparison to a normal contrast population. Changes in total-body calcium (skeletal mass) have also been useful for quantitating the efficacy of various therapies in osteoporosis. Serial measurements over periods of years provide long-term balance data by direct measurement with a higher precision (+- 2%) than is possible by the use of any other technique. In the renal osteodystrophy observed in patients with renal failure, disorders of both calcium and phosphorus, as well as electrolyte disturbances, have been studied. The measure of total-body levels of these elements gives the clinician useful data upon which to design dialysis therapy. The measurement of bone changes in endocrine dysfunction has been studied, particularly in patients with thyroid and parathyroid disorders. In parathyroidectomy, the measurement of total-body calcium, post-operatively, can indicate the degree of bone resorption. Skeletal metabolism and body composition in acromegaly and Cushing's disease have also been investigated by TBNAA. Levels of cadmium in liver and kidney have also been measured in-vivo by prompt-gamma neutron activation and associated with hypertension, emphysema and cigarette smoking.

Book Clinical Total Body in Vivo Neutron Activation Analysis

Download or read book Clinical Total Body in Vivo Neutron Activation Analysis written by Alexander Thomas Elliott and published by . This book was released on 1974 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book In Vivo Neutron Activation Analysis

Download or read book In Vivo Neutron Activation Analysis written by and published by . This book was released on 1984 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: In vivo analysis of body elements by neutron activation is an important tool in medical research. It has provided a direct quantitative measure of body composition of human beings in vivo. Basic physiological differences related to age, sex, race, and body size have been assessed by this noninvasive technique. The diagnosis and management of patients with various metabolic disorders and diseases has also been demonstrated. Two major facilities at Brookhaven are being utilized exclusively for in vivo neutron activation analysis (IVNAA) of calcium, phosphorus, sodium, chlorine, nitrogen, hydrogen, and potassium. These elements serve as the basis for a four compartment model of body composition: protein, water, mineral ash, and fat. Variations in these compartments are demonstrated in clinical research programs investigating obesity, anorexia, cancer, renal failure, osteoporosis, and normal aging. IVNAA continues to provide a unique approach to the evaluation of clinical diagnosis, efficacy of therapeutic regimens, and monitoring of the aging process. Classical balance studies usually require the patient to be admitted to a hospital for extended periods of confinement. IVNAA, however, allows for clinical management of the patient on an out-patient basis, an important aspect for treatment of chronic diseases. 25 references, 3 figures, 5 tables.

Book Some Applications of in Vivo Neutron Activation Analysis to Studies of the Body Composition of Surgical Patients Requiring Nutritional Therapy

Download or read book Some Applications of in Vivo Neutron Activation Analysis to Studies of the Body Composition of Surgical Patients Requiring Nutritional Therapy written by Graham L. Hill and published by . This book was released on 1980 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Design Study of an  in Vivo  Neutron Activation Analysis Clinical Facility for Measuring Total Body Nitrogen

Download or read book Design Study of an in Vivo Neutron Activation Analysis Clinical Facility for Measuring Total Body Nitrogen written by Ion Evangelos M. Stamatelatos and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book In Vivo Neutron Activation Analysis

Download or read book In Vivo Neutron Activation Analysis written by and published by . This book was released on 1973 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Non invasive Techniques for Measuring Body Composition

Download or read book Non invasive Techniques for Measuring Body Composition written by and published by . This book was released on 1985 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past 20 years, in vivo analysis of body elements by neutron activation has become an important tool in medical research. In particular, it provides a much needed means to make quantitative assessments of body composition of human beings in vivo. The data are useful both for basic physiological understanding and for diagnosis and management of a variety of diseases and disorders. This paper traces the development of the in vivo neutron activation technique from basic systems to the present state of the art facilities. A scan of some of the numerous clinical applications that have been made with this technique, reveals the broad potentialities of in vivo neutron activation. The paper also considers alternative routes of future development and raises some of the questions now faced in making the techniques more widely available to both medical practitioners and medical investigators. In vivo neutron activation has opened a new era of both clinical diagnosis and therapy evaluation, and investigation into the modelling of body composition. The techniques are new, but it is already clear that considerable strides can be made in increasing accuracy and precision, increasing the number of elements susceptible to measurement, and reducing the dose required for the measurement. 18 refs., 7 figs.

Book In vivo neutron activation analysis

Download or read book In vivo neutron activation analysis written by Panel on in Vivo Neutron Activation Analysis, Vienna 1972 and published by . This book was released on 1973 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Neutron Activation Analysis for Clinical Trace Element Research

Download or read book Neutron Activation Analysis for Clinical Trace Element Research written by K. Heydorn and published by . This book was released on 1984 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book In Vivo Neutron Activation Analysis  Proceedings

Download or read book In Vivo Neutron Activation Analysis Proceedings written by Panel on In vivo neutron activation analysis, Vienna, 1972 and published by . This book was released on 1973 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book In Vivo Neutron Activation Facility at Brookhaven National Laboratory

Download or read book In Vivo Neutron Activation Facility at Brookhaven National Laboratory written by and published by . This book was released on 1997 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seven important body elements, C, N, Ca, P, K, Na, and Cl, can be measured with great precision and accuracy in the in vivo neutron activation facilities at Brookhaven National Laboratory. The facilities include the delayed-gamma neutron activation, the prompt-gamma neutron activation, and the inelastic neutron scattering systems. In conjunction with measurements of total body water by the tritiated-water dilution method several body compartments can be defined from the contents of these elements, also with high precision. In particular, body fat mass is derived from total body carbon together with total body calcium and nitrogen; body protein mass is derived from total body nitrogen; extracellular fluid volume is derived from total body sodium and chlorine; lean body mass and body cell mass are derived from total body potassium; and, skeletal mass is derived from total body calcium. Thus, we suggest that neutron activation analysis may be valuable for calibrating some of the instruments routinely used in clinical studies of body composition. The instruments that would benefit from absolute calibration against neutron activation analysis are bioelectric impedance analysis, infrared interactance, transmission ultrasound, and dual energy x-ray/photon absorptiometry.