Download or read book Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy written by C. Julian Rosenthal and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first conference on concomitant infusion chemotherapy and radia tion therapy was organized with the intention of bringing together some of the investigators who have tested, during the last few years, the hypo thesis that continuous infusion chemotherapy could modulate the cytotoxic effect of radiation therapy to the point of having a strongly additive, if not synergistic activity on certain malignant tumors. This volume represents the detailed proceedings of this conference presented in a way that offers the reader a review of the on-going re search in the field. We have stressed a number of subjects from basic biologic research and influence of cell kinetics to the practical methods of drug delivery systems and early clinical experiences. The rationale for this new type of combined modality therapy has been presented by some of its pioneers. Early clinical investigations as well as the preliminary data of many that have not yet completely matured have also been included. The reader should look at these data with some reser vations. Ultimately, these results must be confirmed by larger prospective randomized studies with proper controls before becoming accepted as the treatment of choice in locally advanced tumors.
Download or read book Concomitant Continuous Infusion Chemotherapy and Radiation written by Marvin Rotman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: The administration of chemotherapeutic agents by continuous infusion with concomitant radiation therapy heralds a new approach in the treatment of cancer. This comprehensive book on the subject includes, besides a discussion of its scientific basis, the most promising clinical data on the use of continuous infusion chemotherapy and radiation. Thus, it is an important update for clinical investigators involved in frontline research as well as for practicing physicians participating in the direct care of cancer patients. The contributions include the latest results of this new approach in a number of tumor sites. There is a detailed description of the principles of radiosensitization for malignant tumors and radioprotection for normal tissues; these are the principles which have led to concrete clinical applications. There is also a presentation of the most recent data on the beneficial effects resulting from the administration of commonly used drugs, such as 5-fluorouracil, cisplatinum and adriamycin, with concomitant radiation therapy. Much of the data has never before been published. The wealth of information in this volume makes it a valuable reference; at the same time it gives practicing physicians a detailed presentation of various therapeutic regimens which they could administer in their daily clinical practice. In the future, this innovative cancer treatment may lead to the decreased need for radical surgery and the increased ability to preserve organ function.
Download or read book Chemoradiation in Cancer Therapy written by Hak Choy and published by Springer Science & Business Media. This book was released on 2002-12-04 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Internationally recognized experts in cancer biology and clinical research review the present status of the multimodality approach to the management of solid tumors and speculate on possible future strategies for chemoradiation therapy. The authors detail applications of combined modality therapy in lung, esophageal, breast, gastric, pancreatic, colon, and rectal cancers. They also show how radiation interacts with such chemotherapeutic agents as the platinum complexes, taxanes, and gemcitabine in the treatment of malignant gliomas, and head and neck cancer. A review of how to integrate new specific molecular targeted agents into multimodality therapy in the future.
Download or read book Antitumor Drug Radiation Interactions written by Bridget T. Hill and published by CRC Press. This book was released on 2018-01-10 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume reviews the experimental data on drug-radiation interactions. Special emphasis is placed on clinically-useful antitumor drugs. Particular reference is made to appropriate timing, concentration and sequencing of drug-radiation combinations. It includes discussions on the relative merits of experimental data derived from animal versus human tumors. This book also presents a section on the potential for new model systems or alternative test procedures for evaluating therapeutic benefits and cytotoxicities. Results of randomized clinical studies are reviewed with emphasis on recent studies involving protocols specifically designed to test the benefits from optimal integration of chemotherapy with radiotherapy. This book is intended for laboratory researchers in the field and clinicians interested in using the combined modality approach. It is also a useful resource for radiologists, oncologists, and all those interested in cancer research.
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Radiology of Osteoporosis written by Stephan Grampp and published by Springer Science & Business Media. This book was released on 2008-03-18 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of "Radiology of Osteoporosis" has been fully updated so as to represent the current state-of-the-art. It provides a comprehensive overview of osteoporosis, the pathologic conditions that give rise to osteoporosis, and the complications that are frequently encountered. A collection of difficult cases involving pitfalls is presented, with guidance to their solution. The book will be invaluable to all with an interest in osteoporosis.
Download or read book Intracranial Vascular Malformations and Aneurysms written by Michael Forsting and published by Springer Science & Business Media. This book was released on 2008-11-04 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the pathoanatomical, pathophysiological, and imaging features of vascular malformations and aneurysms of the brain and the modern, minimally invasive endovascular methods and techniques employed in their treatment. All chapters in the second revised edition of this book have been thoroughly updated. Readers will find this clearly organized book is richly illustrated with numerous informative CT, MR and DSA images, including high-end 7-Tesla MR images.
Download or read book Pediatric Uroradiology written by Richard Fotter and published by Springer Science & Business Media. This book was released on 2008-11-05 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated and revised edition of a classic work takes full account of recent dramatic changes in the subject area. It describes in detail all aspects of pediatric uroradiology, embracing both recent developments and established concepts. New chapters have been added, for example on genetics in nephrourology and clinical management of important nephrourologic disorders. Short conclusions are included at the end of sections to provide the reader with key information.
Download or read book High Resolution Sonography of the Peripheral Nervous System written by Siegfried Peer and published by Springer Science & Business Media. This book was released on 2008-11-05 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first edition of this book, sonography of the peripheral nervous system has evolved further. This second, revised edition includes many state-of-the-art high-resolution images, the text has been adapted to reflect the current state of the literature, and information is presented using a more modern layout. This book provides a practical, clinically oriented overview of all aspects of sonographic diagnosis and interventional therapy of the peripheral nervous system.
Download or read book Contrast Media written by Henrik S. Thomsen and published by Springer Science & Business Media. This book was released on 2009-03-23 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised edition of Contrast Media: Safety Issues and Guidelines, updates the successful first edition and contains new chapters. It provides an invaluable, unique and unparalleled source of information on the safety issues relating to contrast media.
Download or read book Nasopharyngeal Cancer written by Jiade J. Lu and published by Springer Science & Business Media. This book was released on 2010-01-13 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nasopharyngeal Cancer - Multidisciplinary Management provides a comprehensive account of the current state of knowledge on nasopharyngeal cancer and its multidisciplinary management. The first ten chapters document contain essential background information on subjects such as epidemiology, pathogenesis, molecular biology, pathology, and the use of imaging in diagnosis and staging. Subsequently, the various treatment options and combinations in a range of settings are examined in depth. Detailed attention is given to the roles of concurrent, adjuvant, and neoadjuvant chemotherapy and advanced radiotherapy techniques. Further chapters then explore surgical treatment, follow-up, treatment of metastatic disease, treatment-related complications, and nasopharyngeal cancer in children. This is an important book that will prove essential reading for the radiation oncology community worldwide and meet the need for substantial improvements in knowledge of modern techniques.
Download or read book Virtual Colonoscopy written by Philippe Lefere and published by Springer Science & Business Media. This book was released on 2009-12-11 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid progress in the technique and practice of virtual colonoscopy as well as the conti- ing clinical high interest for this radiodiagnostic procedure made this second edition, only 3 years after the publication of the ? rst edition of this successful volume, necessary. This new edition includes the latest study results and technical developments of this exciting noninvasive diagnostic modality for the evaluation of the colon. The technical presentation and lay out of the text and of the many new illustrations are impeccable. The editors were again able to ensure the collaboration of many international leaders in the ? eld and the book offers a very comprehensive overview of all aspects and issues of CT colonography with a focus on how to perform practically this examination, which requires meticulous technique starting from rigorous preparation, then the conduct of the study itself, and ? nally the interpretation of the results. I am very much indebted to the editors and the collaborating authors for preparing this outstanding volume in a record short time period, which enabled them to include the latest technical advances in this rapidly evolving important radiological method. It is highly recommended to general and gastrointestinal radiologists as well as gast- eneterologists as a most welcome update of their knowledge and as a practical guide in their daily practice. I am convinced that this second edition will meet the same success with our readership as the ? rst one.
Download or read book Coronary Radiology written by Matthijs Oudkerk and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first monograph to focus exclusively on coronary radiology. It is particularly timely, given that the emergence of computed tomography and magnetic resonance imaging, coupled with improvements in both hard- and software, has made reproducible non-invasive coronary imaging a practical reality. A wide range of topics is addressed, including: quantitative angiography, intravascular and quantitative ultrasound, multislice and electron beam computed tomography, magnetic resonance coronary angiography and use of the coronary calcium score as an independent risk factor. All of the latest developments, such as non-invasive intracoronary thrombus imaging, are covered. Particular care has been taken to consider the common questions confronted in asymptomatic patients. The text is supported by high-quality color images of the coronary and cardiac anatomy.
Download or read book Imaging of the Pancreas written by Emil J. Balthazar and published by Springer Science & Business Media. This book was released on 2010-04-10 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using numerous high-quality illustrations, this volume assesses strengths and limitations of techniques for the imaging of pancreatitis. Ultrasound, computed tomography, magnetic resonance imaging and interventional imaging are considered separately in the settings of acute and chronic pancreatitis, with an additional section on imaging of complications. The significance of the imaging findings for clinical and therapeutic decision making is clearly explained, and protocols are provided to help obtain the best possible images.
Download or read book Inflammatory Diseases of the Brain written by Stefan Hähnel and published by Springer Science & Business Media. This book was released on 2009-01-24 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts
Download or read book Functional Preservation and Quality of Life in Head and Neck Radiotherapy written by Paul M. Harari and published by Springer Science & Business Media. This book was released on 2009-06-12 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emphasis on cancer management in the past was based primarily on control rates from multidisciplinary input in management. There has always been a recognition that one would like to achieve the best result with the least complication, but never has there been any major emphasis on evidence-based outcome studies, nor on functional preservation and quality of life. The authors of this book have dealt very effectively with the various tumor types in head and neck cancer with the experts in the ? eld of management. The contents range from epidemiology and treatment outcome, treatment techniques with the potential impact on the quality of life such as dysphagia, to the various options relative to high technology radiation therapy programs for mana- ment. The potential for improving form and function through surgical care as an integrated part of the program is dealt with very effectively as well as the potentials for chemotherapy and the use of targeted agents have on quality of life issues. The volume also addresses toxicity, quality of life, and techniques for prevention of adverse effects, as well as the potentials for rehabilitation and supportive care. The authors have clearly done an extraordinarily good job in addressing the mul- plicity of problems that impact upon the functional preservation and quality of life in head and neck radiation therapy. Philadelphia Luther W.
Download or read book Multimodal Concepts for Integration of Cytotoxic Drugs written by Martin J. Brown and published by Springer Science & Business Media. This book was released on 2006-08-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first part of this book summarizes the rationale and the preclinical data for combined treatment with ionizing radiation and pharmaceutical agents. Individual chapters focus on forms of combined treatment, with due consideration being given to a range of drugs and to emerging combinations with small molecules and antibodies. The second part comprises a series of disease-specific chapters in which the clinical results of combined modality treatment are presented.
