Download or read book Clinical and Molecular Aspects of Cardiomyopathies On the road from gene to therapy An Issue of Heart Failure Clinics written by Giuseppe Limongelli and published by Elsevier Health Sciences. This book was released on 2018-04-02 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Heart Failure Clinics--edited by Drs. Giuseppe Limongelli, Sharlene Day, and Perry Elliott--will cover Clinical and Molecular Aspects of Cardiomyopathies: On the Road from Gene to Therapy. Topics include, but are not limited to, Epidemiology and Clinical aspects of Genetic Cardiomyopathies, Existing and New therapies, Gene editing and gene-based therapeutics, Controversies surrounding exercise in genetic cardiomyopathies, Genetic infiltrative cardiomyopathies, LV Noncompaction, Clinical presentation and natural history of hypertrophic cardiomyopathy in Rasopathies, and Moelcular basis and new treatments of cardiac diseases in Rasopathies.
Download or read book Amiloid Cardiomyopathies Clinical Diagnostic and Therapeutic Aspects An Issue of Heart Failure Clinics E Book written by Giuseppe Limongelli and published by Elsevier Health Sciences. This book was released on 2024-06-07 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Heart Failure Clinics, guest editors Drs. Giuseppe Limongelli, Michele Emdin, Marco Merlo, and Claudio Rapezzi bring their considerable expertise to the topic of Amyloid Cardiomyopathies: Clinical, Diagnostic and Therapeutic Aspects. Top experts in the field discuss the role of clinical use of biomarkers in cardiac amyloidosis; cardiac magnetic resonance in the management of cardiac amyloidosis; bone scintigraphy: strength points and pitfalls in the diagnosis of ATTR-cardiac amyloidosis; PET and cardiac amyloidosis; endomyocardial biopsy in the diagnosis of cardiac amyloidosis; and much more. - Contains 17 relevant, practice-oriented topics including the changing epidemiology of cardiac amyloidosis; arrhythmic stratification of cardiac amyloidosis: state of the art; specific therapy in ATTR-related cardiomyopathy: future perspectives beyond tafamidis; and more. - Provides in-depth clinical reviews on amyloid cardiomyopathies, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Download or read book Advancements in Companion Animal Cardiology An Issue of Veterinary Clinics of North America Small Animal Practice E Book written by Joshua Stern and published by Elsevier Health Sciences. This book was released on 2023-10-05 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Veterinary Clinics: Small Animal Practice, guest editor Dr. Joshua Stern brings his considerable expertise to the topic of Advancements in Companion Animal Cardiology. Cardiovascular disease of companion animals has seen a boom in research productivity and novel therapies that make the future of cardiac care very bright. In this issue, top experts highlight advances in diagnosis and treatment for common cardiac diseases such as hypertrophic cardiomyopathy, mitral valve degeneration, and dilated cardiomyopathy. - Contains 12 relevant, practice-oriented topics including hypertrophic cardiomyopathy: advances in imaging and diagnostic strategies; the genetics of canine pulmonary valve stenosis; mitral valve repair: surgical outcomes and the rise of interventional options; the role of personalized medicine in companion animal cardiology; the role of point-of-care thoracic ultrasound in managing cardiac emergencies; and more. - Provides in-depth clinical reviews on advancements in companion animal cardiology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Download or read book Neuromuscular Disorders of Infancy Childhood and Adolescence written by Basil T. Darras and published by Elsevier. This book was released on 2014-12-03 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuromuscular disorders are diagnosed across the lifespan and create many challenges especially with infants, children and adolescents. This new edition of the definitive reference, edited by the established world renowned authorities on the science, diagnosis and treatment of neuromuscular disorders in childhood is a timely and needed resource for all clinicians and researchers studying neuromuscular disorders, especially in childhood. The Second Edition is completely revised to remain current with advances in the field and to insure this remains the standard reference for clinical neurologists and clinical research neurologists. The Second Edition retains comprehensive coverage while shortening the total chapter count to be an even more manageable and effective reference. - Carefully revised new edition of the classic reference on neuromuscular disorders in infancy, childhood and adolescence. - Definitive coverage of the basic science of neuromuscular disease and the latest diagnosis and treatment best practices. - Includes coverage of clinical phenomenology, electrophysiology, histopathology, molecular genetics and protein chemistry
Download or read book Diagnosis and Management of Hypertrophic Cardiomyopathy written by Barry J. Maron and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnosis and Management of Hypertrophic Cardiomyopathy is aunique, multi-authored compendium of information regarding thecomplexities of clinical and genetic diagnosis, natural history,and management of hypertrophic cardiomyopathy (HCM)—the mostcommon and important of the genetic cardiovasculardiseases—as well as related issues impacting the health oftrained athletes. Edited by Dr. Barry J. Maron, a world authority on HCM, and withmajor contributions from all of the international experts in thisfield, this book provides a single comprehensive source ofinformation concerning HCM. Recent advances in the field arediscussed, including the importance of left ventricular outflowtract obstruction, the use of implantable defibrillators for theprevention of sudden death in young people, definition of thegenetic basis for HCM and its role in clinical diagnosis and riskstratification, the development of more precise strategies forassessing the level of risk for sudden death among all patientswith HCM, and the evolution of invasive interventions for heartfailure symptoms, such as surgical management and its alternatives(alcohol septal ablation and dual-chamber pacing). Key Features: Contributions from all experts in the field,representing diverse viewpoints regarding this heterogeneousdisease and related issues in athletes Information to dispel misunderstandings regarding issuesassociated with HCM and cardiovascular disease in athletes The only comprehensive source of information available on thetopic
Download or read book Genetic Cardiomyopathies written by Gianfranco Sinagra and published by Springer Science & Business Media. This book was released on 2012-12-09 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade, genetics has been emerging as a primary issue in the diagnosis and management of cardiomyopathies. This book is intended to be a state-of-the-art monograph on these diseases, describing their genetic causes, defining the molecular basis and presenting extensive descriptions of genotype–phenotype correlations. Other chapters are focused on the role of clinical observation, on ECG and echocardiography. With its highlight on the most recent discoveries in the field of molecular genetics as well as on the correct clinical approach to patients with heart muscle disease, the book is aimed at physicians and clinical cardiologists with a particular interest in myocardial diseases and in their genetic causes.
Download or read book Inherited cardiac diseases predisposing to sudden death An Issue of Cardiac Electrophysiology Clinics E Book written by Rafik Tadros and published by Elsevier Health Sciences. This book was released on 2023-08-11 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Cardiac Electrophysiology Clinics, guest editors Drs. Rafik Tadros, Julia Cadrin-Tourigny, and Jason D. Roberts bring their considerable expertise to the topic of Inherited Cardiac Diseases Predisposing to Sudden Death. Top experts in the field cover key topics such as genetic counseling and genetic testing in inherited heart disease; implantable devices in genetic heart disease; gene-based therapy in inherited arrythmias and cardiomyopathies; personalized care in long QT syndrome; and more. - Contains 16 relevant, practice-oriented topics including novelties in Brugada syndrome: complex genetics, risk stratification and catheter ablation; novel approaches to treatment of catecholaminergic polymorphic ventricular tachycardia; investigation of unexplained cardiac arrest: phenotyping and genetic testing; impact of imaging to arrhythmic risk stratification in non-ischemic cardiomyopathy; and more. - Provides in-depth clinical reviews on inherited cardiac diseases predisposing to sudden death, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Download or read book Dilated Cardiomyopathy written by Gianfranco Sinagra and published by Springer. This book was released on 2019-05-17 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book presents a comprehensive overview of dilated cardiomyopathy, providing readers with practical guidelines for its clinical management. The first part of the book analyzes in detail the disease’s pathophysiology, its diagnostic work up as well as the prognostic stratification, and illustrates the role of genetics and gene-environment interaction. The second part presents current and future treatment options, highlighting the importance of long-term and individualized treatments and follow-up. Furthermore, it discusses open issues, such as the apparent healing phenomenon, the early prognosis of arrhythmic events or the use of genetic testing in clinical practice. Offering a multidisciplinary approach for optimizing the clinical management of DCM, this book is an invaluable aid not only for the clinical cardiologists, but for all physicians involved in the care of this challenging disease.
Download or read book Rosai and Ackerman s Surgical Pathology E Book written by Juan Rosai and published by Elsevier Health Sciences. This book was released on 2011-06-20 with total page 2767 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rosai and Ackerman’s Surgical Pathology delivers the authoritative guidance you need to overcome virtually any challenge in surgical pathology. Recognized globally for his unmatched expertise, preeminent specialist Juan Rosai, MD brings you state-of-the-art coverage of the latest advancements in immunohistochemistry, genetics, molecular biology, prognostic/predictive markers, and much more - equipping you to effectively and efficiently diagnose the complete range of neoplastic and non-neoplastic entities. Efficiently review the clinical presentation, gross and microscopic features, ultrastructural and immunohistochemical findings, differential diagnosis, therapy, and prognosis for virtually every pathologic entity. Compare your findings to more than 3,300 outstanding illustrations that capture the characteristic presentation of every type of lesion. Avoid diagnostic pitfalls using Dr. Rosai's expert observations on what to look for, what to be careful about, and which presentations can be misleading. Find quick answers on tumor staging, quality control procedures, and the handling of gross specimens through valuable appendices. Make optimal use of all the very latest advances including our increased understanding of the genetic basis of inherited and acquired disease, the newest molecular genetic and immunohistochemical techniques, and the most recent WHO disease classification schemes.
Download or read book Clinical Guide to Cardiology written by Christian Fielder Camm and published by John Wiley & Sons. This book was released on 2016-03-07 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Guide to Cardiology is a quick-reference resource, packed full of bullet points, diagrams, tables and algorithms for the key concepts and facts for important presentations and conditions within cardiology. It provides practical, evidence-based information on interventions, investigations, and the management of clinical cardiology. Key features include: A clear evidence-base providing key guidelines and clinical trials in each chapter Coverage of examination techniques, common conditions, imaging modalities (including ECGs, chest X-rays, MRI and CT), interventional therapies, and pharmacology A companion website at www.wiley.com/go/camm/cardiology featuring audio clips, developed for differing levels of knowledge, that explain key concepts or an area in greater detail, as well as numerous additional clinical case studies, audio scripts, and self-assessment material
Download or read book Cardiovascular Disability written by Institute of Medicine and published by National Academies Press. This book was released on 2010-12-04 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus immediately qualify for benefits. In this report, the IOM makes several recommendations for improving SSA's capacity to determine disability benefits more quickly and efficiently using the Listings.
Download or read book Clinical Cardiogenetics written by H.F. Baars and published by Springer Science & Business Media. This book was released on 2010-12-25 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical management and signs are the focus of this practical cardiogenetic reference for those who are involved in the care for cardiac patients with a genetic disease. With detailed discussion of the basic science of cardiogenetics in order to assist in the clinical understanding of the topic. The genetic causes of various cardiovascular diseases are explained in a concise clinical way that reinforces the current management doctrine in a practical manner. The authors will cover the principles of molecular genetics in general but also specific to cardiac diseases. They will discuss the etiology, pathogenesis, pathophysiology, clinical presentation, clinical diagnosis, molecular diagnosis and treatment of each cardiogenetic disease separately. Therapy advice, ICD indications, indications for and manner of further family investigation will all be covered, while each chapter will also contain take-home messages to reinforce the key points. The chapters reviewing the different diseases will each contain a table describing the genes involved in each. Each chapter will also contain specific illustrations, cumulatively giving a complete, practical review of each cardiogenetic disease separately. Special emphasis will be given to advice on how to diagnose and manage cardiogenetic diseases in clinical practice, which genes should be investigated and why, and the pros and cons of genetic testing. Guidelines for investigation in families with sudden cardiac death at young age will also be included. This book will be written for the general cardiologist and the clinical geneticist who is involved in cardiac patients and will provide answers to question such as: Which genes are involved and which mutations? What is the effect of the mutation at cellular level? Which genes should be tested and why? What is the value of a molecular diagnosis? Does it influence therapy? When should the first degree relatives be tested and in which way?
Download or read book Cardiomyopathy written by Gustav Mattsson and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiomyopathies are diseases of the heart muscle with diverse etiologies ranging from myocarditis to gene mutations. They are classified according to morphology and function, and then further categorized based on whether they are familial or non-familial and based on specific etiologies. This book examines the various cardiomyopathies, including arrhythmogenic cardiomyopathy, hypertrophic cardiomyopathy, and dilated cardiomyopathy, as well as their genetic basis.
Download or read book A Guide to Genetic Counseling written by Wendy R. Uhlmann and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 647 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book devoted exclusively to the principles and practice of genetic counseling—now in a new edition First published in 1998, A Guide to Genetic Counseling quickly became a bestselling and widely recognized text, used nationally and internationally in genetic counseling training programs. Now in its eagerly anticipated Second Edition, it provides a thoroughly revised and comprehensive overview of genetic counseling, focusing on the components, theoretical framework, and unique approach to patient care that are the basis of this profession. The book defines the core competencies and covers the genetic counseling process from case initiation to completion—in addition to addressing global professional issues—with an emphasis on describing fundamental principles and practices. Chapters are written by leaders in the field of genetic counseling and are organized to facilitate academic instruction and skill attainment. They provide the most up-to-date coverage of: The history and practice of genetic counseling Family history Interviewing Case preparation and management Psychosocial counseling Patient education Risk communication and decision-making Medical genetics evaluation Understanding genetic testing Medical documentation Multicultural counseling Ethical and legal issues Student supervision Genetic counseling research Professional development Genetics education and outreach Evolving roles and expanding opportunities Case examples A Guide to Genetic Counseling, Second Edition belongs on the syllabi of all medical and human genetics and genetic counseling training programs. It is an indispensable reference for both students and healthcare professionals working with patients who have or are at risk for genetic conditions.
Download or read book Promoting Safe and Effective Genetic Testing in the United States written by Task Force on Genetic Testing (U.S.) and published by . This book was released on 1998-07-24 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: In view of this uncertainty, the Working Group on Ethical, Legal, and Social Implications of Human Genome Research at the National Institutes of Health and Department of Energy created the Task Force on Genetic Testing.
Download or read book Additional Protocol to the Convention on Human Rights and Biomedicine Concerning Genetic Testing for Health Purposes written by Council of Europe and published by Council of Europe. This book was released on 2008-01-01 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological and medical research has led to remarkable progress in the field of human health. The rapid developments in this sphere have prompted the Council of Europe to consider the ethical and legal aspects of applications of genetics, particularly genetic testing, and to draw up legal rules to protect fundamental human rights with regard to these applications. The new Protocol sets down principles relating inter alia to the quality of genetic services, prior information and consent and genetic counselling. It lays down general rules on the conduct of genetic tests, and, for the first time at international level, deals with the directly accessible genetic tests for which a commercial offer could develop in future. It specifies the conditions in which tests may be carried out on persons not able to consent. Also covered are the protection of private life and the right to information collected through genetic testing. Finally, the Protocol touches on genetic screening.
Download or read book Depression and Heart Disease written by Alexander Glassman and published by John Wiley & Sons. This book was released on 2011-06-20 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, there has been a growing awareness of the multiple interrelationships between depression and various physical diseases. Patients with psychiatric problems, particularly depression, may be more susceptible to cardiovascular disorders. Depression and Heart Disease synthesizes current evidence, including some previously unpublished data, in a concise, easy-to-read format. The authors succinctly describe the epidemiology, pathogenesis (including cytokines and genetics), and risk factors of the comorbidity between depression and heart disease. The book also reviews the best pharmacological and psychotherapeutic approaches for people with this comorbidity.
