Download or read book Clinic oriented Multifunctional Biomaterials From Rational Design to Applications written by Meng Tian and published by Frontiers Media SA. This book was released on 2023-12-13 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Rational Design and Characterization of Innovative Multifunctional Biomimetic Materials written by Lia Rimondini and published by Frontiers Media SA. This book was released on 2021-04-13 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunomodulatory Biomaterials written by Stephen F. Badylak and published by Woodhead Publishing. This book was released on 2021-07-30 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials have existed for millennia as mechanical replacement structures following disease or injury. Biomaterial design has changed markedly from structural support with an "inert immune profile as the primary objective to designs that elicit an integrative local tissue response and a pro-repair immune cell phenotype. Immunomodulatory Biomaterials: Regulating the Immune Response with Biomaterials to Affect Clinical Outcome offers a single, comprehensive reference on biomaterials for modulation of the host response, for materials scientists, tissue engineers and those working in regenerative medicine. This book details methods, materials and strategies designed to regulate the host immune response following surgical implantation and thus facilitate specific local cell infiltration and tissue deposition. There has been a dramatic transformation in our understanding of the role of the immune system, both innate and adaptive; these changes include recognition of the plasticity of immune cells, especially macrophages, cross-talk between the immune system and stem cells, and the necessity for in situ transition between inflammatory and regulatory immune cell phenotypes. The exploitation of these findings and the design and manufacture of new biomaterials is occurring at an astounding pace. There is currently no book directed at the interdisciplinary principles guiding the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response. The challenge for academia, industry, and regulatory agencies to encourage innovation while assuring safety and maximizing efficacy has never been greater. Given the highly interdisciplinary requirements for the design, manufacture and use of immunomodulatory biomaterials, this book will prove a useful single resource across disciplines. - Holistically covers the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response - Provides a single reference for understanding and utilizing the host response in biomaterials design - An international collaboration of leading researchers in the field offering a novel insight into this fast-growing area
Download or read book Engineering Biomaterials for Regenerative Medicine written by Sujata K. Bhatia and published by Springer Science & Business Media. This book was released on 2011-11-10 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regeneration of tissues and organs remains one of the great challenges of clinical medicine, and physicians are constantly seeking better methods for tissue repair and replacement. Tissue engineering and regenerative medicine have been investigated for virtually every organ system in the human body, and progress is made possible by advances in materials science, polymer chemistry, and molecular biology. This book reviews the current status of biomaterials for regenerative medicine, and highlights advances in both basic science and clinical practice. The latest methods for regulating the biological and chemical composition of biomaterials are described, together with techniques for modulating mechanical properties of engineered constructs. Contributors delineate methods for guiding the host response to implantable materials, and explain the use of biologically-inspired materials for optimal biological functionality and compatibility. The book culminates in a discussion of the clinical applications of regenerative medicine. By integrating engineering and clinical medicine, Engineering Biomaterials for Regenerative Medicine examines how tissue engineering and regenerative medicine can be translated into successful therapies to bridge the gap between laboratory and clinic. The book will aid materials scientists and engineers in identifying research priorities to fulfill clinical needs, and will also enable physicians to understand novel biomaterials that are emerging in the clinic. This integrated approach also gives engineering students a sense of the excitement and relevance of materials science in the development of novel therapeutic strategies.
Download or read book Functional Biomaterials written by Sougata Jana and published by Springer Nature. This book was released on 2022-03-29 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores in depth a wide range of functional biomaterials-based systems for drug, gene delivery, and biomedical aspects. The chapters cover newer technologies such as polymeric micelle, pH-responsive biomaterials, stimuli-responsive hydrogels, silk fibroin, inorganic biomaterials, synthetic biomaterials, 3D printed biomaterials, metallic biomaterials, ceramic and hybrid biomaterials. It also describes the theranostic approaches for cancer therapy, the biomaterials-based nanofibers scaffolds in tissue engineering, as well as the strategies applications of metallic biomaterials for the medical and dental prosthetic field. This newer and updated approach will be attractive for biomedical engineering students working on materials science in the development of novel drug delivery strategies. The book will be an important reference for researchers and professionals working on biomaterial research in the pharmaceutical and medical fields.
Download or read book Rational and Combinatorial Design of Biomaterials for Tissue Engineering Applications written by Sriram Ramamoorthy and published by . This book was released on 2015 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biomedical Nanostructures written by Kenneth Gonsalves and published by John Wiley & Sons. This book was released on 2007-11-09 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to Use Nanoscale Materials to Design Novel Biomedical Devices and Applications Discover how to take full advantage of nanoscale materials in the design and fabrication of leading-edge biomedical devices. The authors introduce you to a variety of possible clinical applications such as drug delivery, diagnostics, and cancer therapy. In addition, the authors explore the interface between micron and nanoscale materials for the development of applications such as tissue engineering. Finally, they examine the mechanisms of cell interactions with material surfaces through the use of nanotechnology-based material processing and characterization methods. The text's three sections highlight its interdisciplinary approach: * Part One: Nanostructure Fabrication * Part Two: Bio-Nano Interfaces * Part Three: Clinical Applications of Nanostructures Among the key topics covered are nanotechnology in tissue regeneration; biomolecular engineering; receptor-ligand interactions; cell-biomaterial interactions; nanomaterials in diagnostics, drug delivery, and cancer therapy; and nano- and micron-level engineering and fabrication. Throughout the text, clear examples guide you through the chemistry and the processing involved in designing and developing nanoscale materials for biomedical devices. Each chapter begins with an introduction and ends with a conclusion highlighting the key points. In addition, references at the end of the chapter help you expand your research on any individual topic. In summary, this book helps biomedical researchers and engineers understand the physical phenomena that occur at the nanoscale in order to design novel cell-based constructs for a wide range of applications.
Download or read book Multi Functional Collagen Based Biomaterials for Biomedical Applications written by Nunzia Gallo and published by Mdpi AG. This book was released on 2023-03-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymeric biomaterials represent an essential tool in the biomedical field. Their high biocompatibility and ability to provide adequate regenerative support are fundamental for the development of new therapeutic devices. In particular, biomaterials derived from living organisms can exhibit not only structural roles but also several non-structural functions implicated in cellular growth, migration, and differentiation. Among them, type I collagen, a ubiquitous structural protein present in the mammalian body, plays a dominant role in maintaining the biological and structural integrity of various tissues. In recent years, with the goal of developing multi-functional collagen-based devices able to better promote the functional recovery of damaged tissues, numerous studies have focused on novel techniques and methods for the development and characterization of innovative and advanced high-performance formulations. The ability to control, modify, and tune collagen-based biomaterials performance by optimizing their architecture, besides modifying their chemistry, blending with other materials/therapeutics, or developing stimuli-responsive formulations, is an extremely important knowledge to acquire when specific multi-functionalities are sought. The present Special Issue collected 12 peer-reviewed interdisciplinary contributions on the broad topic of multi-functional collagen-based biomaterials.
Download or read book Self assembling Biomaterials written by Helena S. Azevedo and published by Woodhead Publishing. This book was released on 2018-04-17 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: Self-assembling biomaterials: molecular design, characterization and application in biology and medicine provides a comprehensive coverage on an emerging area of biomaterials science, spanning from conceptual designs to advanced characterization tools and applications of self-assembling biomaterials, and compiling the recent developments in the field. Molecular self-assembly, the autonomous organization of molecules, is ubiquitous in living organisms and intrinsic to biological structures and function. Not surprisingly, the exciting field of engineering artificial self-assembling biomaterials often finds inspiration in Biology. More important, materials that self-assemble speak the language of life and can be designed to seamlessly integrate with the biological environment, offering unique engineering opportunities in bionanotechnology. The book is divided in five parts, comprising design of molecular building blocks for self-assembly; exclusive features of self-assembling biomaterials; specific methods and techniques to predict, investigate and characterize self-assembly and formed assemblies; different approaches for controlling self-assembly across multiple length scales and the nano/micro/macroscopic properties of biomaterials; diverse range of applications in biomedicine, including drug delivery, theranostics, cell culture and tissue regeneration. Written by researchers working in self-assembling biomaterials, it addresses a specific need within the Biomaterials scientific community. - Explores both theoretical and practical aspects of self-assembly in biomaterials - Includes a dedicated section on characterization techniques, specific for self-assembling biomaterials - Examines the use of dynamic self-assembling biomaterials
Download or read book Nanostructured Biomaterials for Overcoming Biological Barriers written by Maria Jose Alonso and published by Royal Society of Chemistry. This book was released on 2012 with total page 643 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a critical overview of the advances being made toward overcoming biological barriers through the contribution of nanosciences and nanotechnologies to solve the problems of many current drugs and vaccines.
Download or read book Shape Memory Polymers for Biomedical Applications written by L Yahia and published by Elsevier. This book was released on 2015-03-19 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shape memory polymers (SMPs) are an emerging class of smart polymers which give scientists the ability to process the material into a permanent state and predefine a second temporary state which can be triggered by different stimuli. The changing chemistries of SMPs allows scientists to tailor important properties such as strength, stiffness, elasticity and expansion rate. Consequently SMPs are being increasingly used and developed for minimally invasive applications where the material can expand and develop post insertion. This book will provide readers with a comprehensive review of shape memory polymer technologies. Part 1 will discuss the fundamentals and mechanical aspects of SMPs. Chapters in part 2 will look at the range of technologies and materials available for scientific manipulation whilst the final set of chapters will review applications. - Reviews the fundamentals of shape memory polymers with chapters focussing on the basic principles of the materials - Comprehensive coverage of design and mechanical aspects of SMPs - Expert analysis of the range of technologies and materials available for scientific manipulation
Download or read book Application of Nanocarriers in Brain Delivery of Therapeutics written by Amit Alexander and published by Springer Nature. This book was released on with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Smart Biomaterials written by Mitsuhiro Ebara and published by Springer. This book was released on 2014-05-28 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive coverage of smart biomaterials and their potential applications, a field that is developing at a very rapid pace. Because smart biomaterials are an emerging class of biomaterials that respond to small changes in external stimuli with large discontinuous changes in their physical properties, they have been designed to act as an “on–off” switch for, among others, bio separation, immunoanalysis, drug delivery technologies, gene therapy, diagnostics, bio sensors and artificial muscles. After an introduction to the topic and the history of smart biomaterials, the author gives the reader an in-depth look at the properties, mechanics, and characterization of smart biomaterials including hydrogels, particles, assemblies, surfaces, fibers and conjugates. Information on the wide range of applications for these materials follows, including drug delivery, tissue engineering, diagnostics, biosensors, bio separation and actuators. In addition, recent advances in shape memory biomaterials as active components of medical devices are also presented.
Download or read book Exploration of innovative strategies focusing on advanced nanobiomaterials for optimizing oncological treatment and tissue restoration written by Weifeng Lin and published by Frontiers Media SA. This book was released on 2023-09-08 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Transglutaminase written by Yi Zhang and published by Elsevier. This book was released on 2024-03-15 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transglutaminase: Fundamentals and Applications, a new volume in the Foundations and Frontiers in Enzymology series, stands as a comprehensive resource on this increasingly important class of enzymes. Following an introduction to the field from the Editors, international experts discuss basic biology and structure – function relationships of transglutaminases, ongoing fundamental research, as well as new application areas, including food processing, material synthesis, biomedicine and disease treatment, and biotechnology. Approaches for sourcing transglutaminases from animals, plants, and microorganisms are considered in-depth, followed by chapters on applied uses in biomedicine, skin and bone biology and medicine, drug development, tissue engineering, seafood bioprocessing, dairy bioprocessing, synthesis of materials and polymers, and as an immobilization agent. Research protocols are also provided, including research rationale, design, substrates, assays and microassay steps for studying transglutaminases. Brings together basic knowledge and applied research on transglutaminase biology Considers a range of application areas, from biomedicine to drug development, tissue engineering, food processing, and materials synthesis Includes instructive protocols for basic and applied transglutaminase research Features chapter contributions from global leading experts in the field, across disciplines and applications
Download or read book Biomedical Applications of Nanoparticles written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2019-02-28 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Applications of Nanoparticles describes the most interesting and investigated biomedical applications of nanoparticles, emphasizing their therapeutic impact. Progress made in the therapy of severe diseases, such as cancer and difficult infections is strictly correlated to the scientific progress and technological development in the field of materials science. Nanoparticles have numerous therapeutic applications, starting with the design of new drugs, delivery systems, therapeutic materials, and their contribution to the development of preventive strategies. The book highlights the impact of nanoparticles on the therapy of infections, antimicrobial effect and also anti-cancer strategies. Successful examples are given throughout the book, along with analysis in order to improve future outcomes of novel therapies. - Highlights the term nanotherapeutics and presents several classifications of nanotherapeutics from different points-of-view - Presents the recent progress related to nanotherapeutics in the oral cavity - Provides the recent progress in the field of biomedical nanoparticles
Download or read book Immunological Effects of Nano Imaging Materials written by Yang Li and published by Frontiers Media SA. This book was released on 2022-04-18 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt:
