Download or read book Mapping and Sequencing the Human Genome written by National Research Council and published by National Academies Press. This book was released on 1988-01-01 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
Download or read book Chromosome Mapping Research Developments written by Jennifer F. Verrity and published by Nova Publishers. This book was released on 2008 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromosome mapping is the construction of a series of chromosome descriptions that depict the position and spacing of unique, identifiable biochemical landmarks, including some genes that occur on the DNA of chromosomes. This new book is devoted to the latest research in the field.
Download or read book Gene Mapping Techniques and Applications written by Lawrence B. Schook and published by CRC Press. This book was released on 2020-07-24 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains current strategies for mapping genomes of higher organisms and explores applications of gene mapping to agriculturally important species of plants and animals. It also explores the experimental techniques used for genetic and physical mapping of genes.
Download or read book Human Chromosomes written by Orlando J. Miller and published by Springer Science & Business Media. This book was released on 2011-06-28 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fourth edition of this well-known text provides students, researchers and technicians in the area of medicine, genetics and cell biology with a concise, understandable introduction to the structure and behavior of human chromosomes. This new edition continues to cover both basic and up-to-date material on normal and defective chromosomes, yet is particularly strengthened by the complete revision of the material on the molecular genetics of chromosomes and chromosomal defects. The mapping and molecular analysis of chromosomes is one of the most exciting and active areas of modern biomedical research, and this book will be invaluable to scientists, students, technicians and physicians with an interest in the function and dysfunction of chromosomes.
Download or read book The Statistics of Gene Mapping written by David Siegmund and published by Springer Science & Business Media. This book was released on 2007-05-27 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book details the statistical concepts used in gene mapping, first in the experimental context of crosses of inbred lines and then in outbred populations, primarily humans. It presents elementary principles of probability and statistics, which are implemented by computational tools based on the R programming language to simulate genetic experiments and evaluate statistical analyses. Each chapter contains exercises, both theoretical and computational, some routine and others that are more challenging. The R programming language is developed in the text.
Download or read book Mapping our genes the genome projects how big how fast written by and published by DIANE Publishing. This book was released on 1988 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genetic Mapping in Experimental Populations written by J. W. Van Ooijen and published by Cambridge University Press. This book was released on 2013-08-08 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise introduction to genetic linkage map construction for biological researchers, combining theory with practical exercises and problem-solving tips.
Download or read book Statistical Genetics written by Benjamin Neale and published by Garland Science. This book was released on 2007-11-30 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Genetics is an advanced textbook focusing on conducting genome-wide linkage and association analysis in order to identify the genes responsible for complex behaviors and diseases. Starting with an introductory section on statistics and quantitative genetics, it covers both established and new methodologies, providing the genetic and statistical theory on which they are based. Each chapter is written by leading researchers, who give the reader the benefit of their experience with worked examples, study design, and sources of error. The text can be used in conjunction with an associated website (www.genemapping.org) that provides supplementary material and links to downloadable software.
Download or read book Gene Mapping Discovery and Expression written by Minou Bina and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completion of the sequence of the human genome represents an unpar- leled achievement in the history of biology. The project has produced nearly complete, highly accurate, and comprehensive sequences of genomes of s- eral organisms including human, mouse, drosophila, and yeast. Furthermore, the development of high-throughput technologies has led to an explosion of projects to sequence the genomes of additional organisms including rat, chimp, dog, bee, chicken, and the list is expanding. The nearly completed draft of genomic sequences from numerous species has opened a new era of research in biology and in biomedical sciences. In keeping with the interdisciplinary nature of the new scientific era, the chapters in Gene Mapping, Discovery, and Expression: Methods and Protocols recapitulate the necessity of integration of experimental and computational tools for solving - portant research problems. The general underlying theme of this volume is DNA sequence-based technologies. At one level, the book highlights the importance of databases, genome-browsers, and web-based tools for data access and ana- sis. More specifically, sequencing projects routinely deposit their data in p- licly available databases including GenBank, at the National Center of Biotechnology (NCBI) in the United States; EMBL, maintained by the European Bioinformatics Institute; and DDBJ, the DNA Data Bank of Japan. Currently, several browsers offer facile access to numerous genomic DNA sequences for gene mapping and data retrieval.
Download or read book Human Gene Mapping 1995 written by A. Jamie Cuticchia and published by . This book was released on 1996 with total page 1768 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current status of the human genome map with information through 8 January 1996 A comprehensive listing of mapped human genes, anonymous DNA segments, and polymorphic markers In the years since the first Human Gene Mapping Conference in 1973, the number of genes included in the Genome Data Base has reached 5,902. In the past several years, there has been enormous growth not only in the numbers of markers localized to the map but also in the speed of the process of placement of such markers. This compendium provides a convenient summary list of markers and abbreviated literature citations to indicate which mapping reagents are available. While the most current information on the human genome can be obtained via on-line GDB, the annual published reports on the status of the human gene map are a valuable resource for the extensive research community engaged in genetic and physical mapping of the human genome. Starting with the 1993 compendium, this publication has supplanted the previous Chromosome Coordinating Meeting report and the Human Gene Mapping volumes. Reflecting the editing of the Genome Data Base through 8 January 1996, Human Gene Mapping, 1995 includes (as have the prior publications) the most recent reports of the chromosome mapping committees as well as reports from the nomenclature, comparative mapping, linkage, neoplasia, and clinical disorders committees.
Download or read book Calculating the Secrets of Life written by National Research Council and published by National Academies Press. This book was released on 1995-04-06 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: As researchers have pursued biology's secrets to the molecular level, mathematical and computer sciences have played an increasingly important roleâ€"in genome mapping, population genetics, and even the controversial search for "Eve," hypothetical mother of the human race. In this first-ever survey of the partnership between the two fields, leading experts look at how mathematical research and methods have made possible important discoveries in biology. The volume explores how differential geometry, topology, and differential mechanics have allowed researchers to "wind" and "unwind" DNA's double helix to understand the phenomenon of supercoiling. It explains how mathematical tools are revealing the workings of enzymes and proteins. And it describes how mathematicians are detecting echoes from the origin of life by applying stochastic and statistical theory to the study of DNA sequences. This informative and motivational book will be of interest to researchers, research administrators, and educators and students in mathematics, computer sciences, and biology.
Download or read book Workshop on Human Gene Mapping written by and published by . This book was released on 1988 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Gene Mapping in Laboratory Mammals written by Roy. Robinson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present work is an attempt to provide a systematic treatment of genetic linkage in diploid heredity. Part A presents a general account of statistical methods which can be brought to bear on the problem. The primary emphasis is on the practical aspects of estimation. A large proportion, if not the majority, of mutant genes fail to match up to 'textbook' genes-with faultless segregation ratios and expression-yet, these are the materials with which the practical researcher has to cope. For this reason, it is important to know how to deal with the assortment of genes which may display significant deviations from expectation. Part B examines the accumulated data on linkage for most of the laboratory mammals and provides a comprehensive and up-to-date survey. The need for a critical review has often been expressed and it is hoped that the present analysis will fill the gap. The volume of material is probably the most important in the animal kingdom other than that for Drosophila species.
Download or read book Linkage and Chromosome Mapping in Man written by Bronya J. B. Keats and published by University of Hawaii Press. This book was released on 1981 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Potato Genome written by Swarup Kumar Chakrabarti and published by Springer. This book was released on 2017-12-26 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the historical importance of potato (Solanum tuberosum L.),potato genetic resources and stocks (including S. tuberosum group Phureja DM1-3 516 R44, a unique doubled monoploid homozygous line) used for potato genome sequencing. It also discusses strategies and tools for high-throughput sequencing, sequence assembly, annotation, analysis, repetitive sequences and genotyping-by-sequencing approaches. Potato (Solanum tuberosum L.; 2n = 4x = 48) is the fourth most important food crop of the world after rice, wheat and maize and holds great potential to ensure both food and nutritional security. It is an autotetraploid crop with complex genetics, acute inbreeding depression and a highly heterozygous nature. Further, the book examines the recent discovery of whole genome sequencing of a few wild potato species genomes, genomics in management and genetic enhancement of Solanum species, new strategies towards durable potato late blight resistance, structural analysis of resistance genes, genomics resources for abiotic stress management, as well as somatic cell genetics and modern approaches in true-potato-seed technology. The complete genome sequence provides a better understanding of potato biology, underpinning evolutionary process, genetics, breeding and molecular efforts to improve various important traits involved in potato growth and development.
Download or read book Mapping Our Genes written by Lois Wingerson and published by Plume Books. This book was released on 1991 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eye-opening and mind-expanding, "Mapping Our Genes" tells of the experts who are brightly hopeful about using genetic mapping and engineering as weapons in the war against the many incurable genetically inherited maladies.
Download or read book Travelling Around the Human Genome written by Bertrand Jordan and published by John Libbey Eurotext. This book was released on 1993 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt:
