Download or read book Physiology and Pathology of Chloride Transporters and Channels in the Nervous System written by F. Javier Alvarez-Leefmans and published by Academic Press. This book was released on 2009-08-22 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of chloride ions in cell physiology has not been fully recognized until recently, in spite of the fact that chloride (Cl-), together with bicarbonate, is the most abundant free anion in animal cells, and performs or determines fundamental biological functions in all tissues. For many years it was thought that Cl- was distributed in thermodynamic equilibrium across the plasma membrane of most cells. Research carried out during the last couple of decades has led to a dramatic change in this simplistic view. We now know that most animal cells, neurons included, exhibit a non-equilibrium distribution of Cl- across their plasma membranes. Over the last 10 to 15 years, with the growth of molecular biology and the advent of new optical methods, an enormous amount of exciting new information has become available on the molecular structure and function of Cl- channels and carriers. In nerve cells, Cl- channels and carriers play key functional roles in GABA- and glycine-mediated synaptic inhibition, neuronal growth and development, extracellular potassium scavenging, sensory-transduction, neurotransmitter uptake and cell volume control. Disruption of Cl- homeostasis in neurons underlies pathological conditions such as epilepsy, deafness, imbalance, brain edema and ischemia, pain and neurogenic inflammation. This book is about how chloride ions are regulated and how they cross the plasma membrane of neurons. It spans from molecular structure and function of carriers and channels involved in Cl- transport to their role in various diseases. The first comprehensive book on the structure, molecular biology, cell physiology, and role in diseases of chloride transporters / channels in the nervous system in almost 20 years Chloride is the most abundant free anion in animal cells. THis book summarizes and integrates for the first time the important research of the past two decades that has shown that Cl- channels and carriers play key functional roles in GABA- and glycine-mediated synaptic inhibition, neuronal growth and development, extracellular potassium scavenging, sensory-transduction, neurotransmitter uptake and cell volume control The first book that systematically discusses the result of disruption of Cl- homeostasis in neurons which underlies pathological conditions such as epilepsy, deafness, imbalance, brain edema and ischemia, pain and neurogenic inflammation Spanning topics from molecular structure and function of carriers and channels involved in Cl- transport to their role in various diseases Involves all of the leading researchers in the field Includes an extensive introductory section that covers basic thermodynamic and kinetics aspects of Cl- transport, as well as current methods for studying Cl- regulation, spanning from fluorescent dyes in single cells to knock-out models to make the book available for a growing population of graduate students and postdocs entering the field

Download or read book Dietary Reference Intakes for Water Potassium Sodium Chloride and Sulfate written by Institute of Medicine and published by National Academies Press. This book was released on 2005-06-18 with total page 639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate The Dietary Reference Intakes (DRIs) are quantitative estimates of nutrient intakes to be used for planning and assessing diets for healthy people. This new report, the sixth in a series of reports presenting dietary reference values for the intakes of nutrients by Americans and Canadians, establishes nutrient recommendations on water, potassium, and salt for health maintenance and the reduction of chronic disease risk. Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate discusses in detail the role of water, potassium, salt, chloride, and sulfate in human physiology and health. The major findings in this book include the establishment of Adequate Intakes for total water (drinking water, beverages, and food), potassium, sodium, and chloride and the establishment of Tolerable Upper Intake levels for sodium and chloride. The book makes research recommendations for information needed to advance the understanding of human requirements for water and electrolytes, as well as adverse effects associated with the intake of excessive amounts of water, sodium, chloride, potassium, and sulfate. This book will be an invaluable reference for nutritionists, nutrition researchers, and food manufacturers.

Download or read book Diffusion of Chloride in Concrete written by E. Poulsen and published by CRC Press. This book was released on 2014-04-21 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the most comprehensive and flexible theory of chloride ingress in concrete to date. Based on test results and field observations, the book demonstrates the easy application of this theory to practice. The information is presented in a clear style with each chapter containing an introduction, technical applications and examples, and a f

Download or read book Diffusion of Chloride in Concrete written by E. Poulsen and published by CRC Press. This book was released on 2010-02-25 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the most comprehensive and flexible theory of chloride ingress in concrete to date. Based on test results and field observations, the book demonstrates the easy application of this theory to practice. The information is presented in a clear style with each chapter containing an introduction, technical applications and examples, and a final section covering the mathematics behind the theory, to enable the reader to obtain a deeper insight into the subject. Primarily aimed at practising engineers engaged in analysis and design of concrete structures exposed to a chloride laden environment, this book is also a useful reference for mathematicians and engineering students.

Download or read book Practical Guide to Polyvinyl Chloride written by Stuart Patrick and published by iSmithers Rapra Publishing. This book was released on 2005 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyvinyl chloride (PVC) has been around since the late part of the 19th century, although it was not produced commercially until the 1920s; it is the second largest consumed plastic material after polyethylene. PVC products can be rigid or flexible, opaque or transparent, coloured, and insulating or conducting. There is not just one PVC but a whole family of products tailor-made to suit the needs of each application. PVC is extremely cost effective in comparison to other plastics with a high degree of versatility in end-use and processing possibilities, as the reader will note from this book. It is durable, easily maintained, and can be produced in a large range of colours. As a result PVC finds use in an extensive range of applications in virtually all areas of human activity, including medical equipment, construction applications such as flexible roof membranes, pipes and window profiles, toys, automotive parts and electrical cabling. The PVC industry has also started to tackle some of its end-of-life issues. This practical guide provides comprehensive background on the resins and additives, their properties and processing characteristics, as well as discussion of product design and development issues. There have been, and still are, issues and perceptions over environmental and health acceptance covering vinyl chloride monomer, dioxins, phthalate plasticisers, and lead (and cadmium) based heat stabilisers and these are discussed in depth in this book. This book will be of interest to raw materials suppliers and processors or end-users of PVC, as well as anyone with a general interest in this versatile material: resins and additives properties and testing design issues processing, including post processing and assembly property enhancement sustainable development

Download or read book Chlorine and Hydrogen Chloride written by Assembly of Life Sciences (U.S.). Committee on Medical and Biologic Effects of Environmental Pollutants and published by . This book was released on 1976 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1 INTRODUCTION. 2 SOURCERS OF CHLORINE AND HYDROGEN CHLORIDE. 3 CONSUMPTION OF CHLORINE AND HYDROGEN CHLORIDE. 4 ATMOSPHERIC CHEMISTRY OF CHLORINE COMPOUNDS. 5 EFFECTS OF CHLORINE AND HYDROGEN CHLORIDE ON MAN AND ANIMALS. 6 EFFECTS OF CHLORINE AND HYDROGEN CHLORIDE ON VEGETATION. 7 PROPERTY DAMAGE AND PUBLIC NUISANCE. 8 SAFETY IN USE AND HANDLING OF CHLORINE AND ANHYDROUS HYDROGEN CHLORIDE.

Download or read book Handbook of Lithium and Natural Calcium Chloride written by Donald E. Garrett and published by Elsevier. This book was released on 2004-04-05 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Lithium and Natural Calcium Chloride is concerned with two major industrial minerals: Lithium and Calcium Chloride. The geology of their deposits is first reviewed, along with discussions of most of the major deposits and theories of their origin. The commercial mining and processing plants are next described, followed by a review of the rather extensive literature on other proposed processing methods. The more important uses for lithium and calcium chloride are next covered, along with their environmental considerations. This is followed by a brief review of the production statistics for each industry, and some of their compounds' phase data and physical properties. Describes the chemistry, chemical engineering, geology and mineral processing aspects of lithium and calcium chloride Collects in one source the most important information concerning these two industrial minerals Presents new concepts and more comprehensive theories on their origin

Download or read book Cell Volume Regulation written by Florian Lang and published by S. Karger AG (Switzerland). This book was released on 1998 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents a unique compilation of reviews on cell volume regulation in health and disease, with contributions from leading experts in the field. The topics covered include mechanisms and signaling of cell volume regulation and the effect of cell volume on cell function, with special emphasis on ion channels and transporters, kinases and gene expression. Several chapters elaborate on how cell volume regulatory mechanisms participate in the regulation of epithelial transport, urinary concentration, metabolism, migration, cell proliferation and apoptosis. Last but not least, this publication is an excellent guide to the role of cell volume in the pathophysiology of hypercatabolism, diabetes mellitus, brain edema, hemoglobinopathies, tumor growth and metastasis, to name just a few. Providing deeper insights into an exciting area of research which is also of clinical relevance, this publication is a valuable addition to the library of those interested in cell volume regulation.

Download or read book Water Softening with Potassium Chloride written by Rod McEachern and published by John Wiley & Sons. This book was released on 2009-09-17 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Potassium chloride is a logical alternative to sodium chloride in water softening. Water Softening with Potassium Chloride provides a thorough overview of the process, the equipment, and the techniques used. Then it compiles diverse trade and technical data on water softening with potassium chloride so readers can make informed decisions. It documents the health and environmental consequences and benefits of using potassium chloride and includes a chapter with summaries of recent research projects and FAQs. This is a key reference for professional water treatment specialists, environmental science researchers, and others.

Download or read book Re evaluation of Some Organic Chemicals Hydrazine and Hydrogen Peroxide written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by . This book was released on 1999 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Water Chemicals Codex written by National Research Council and published by National Academies Press. This book was released on 1982-02-01 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Chloride Movements Across Cellular Membranes written by and published by Elsevier Science. This book was released on 2007-01-22 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: All living cells are surrounded by a lipidic membrane that isolates them from the often harsh environment. However, to take up nutrients, to excrete waste, and to communicate among each other, Nature has invented an incredibly diverse set of transmembrane transport proteins. Specialized transporters exist to shuttle electrically charged ions, positive cations like sodium or negative anions like chloride, across the membrane. In the recent years, tremendous progress has been made in the field of chloride transport. The present book presents the state of the art of this rapidly expanding and interest-gaining field of membrane transport. It is addressed at a broad medically, physiologically, biologically, and biophysically interested readership. Describes the state-of-the-art in anion transport research Written by leaders in the field Presents a timely discussion of this rapidly emerging and expanding field

Download or read book Solubilities of Chloride Salts of Alkali and Alkaline earth Metals when Sparged with Hydrogen Chloride written by Elaine G. Noble and published by . This book was released on 1985 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Inorganic Syntheses written by and published by John Wiley & Sons. This book was released on 2009-09-22 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volumes in this continuing series provide a compilation of current techniques and ideas in inorganic synthetic chemistry. Includes inorganic polymer syntheses and preparation of important inorganic solids, syntheses used in the development of pharmacologically active inorganic compounds, small-molecule coordination complexes, and related compounds. Also contains valuable information on transition organometallic compounds including species with metal-metal cluster molecules. All syntheses presented here have been tested.

Download or read book Geriatric Gastroenterology written by C. S. Pitchumoni and published by Springer Science & Business Media. This book was released on 2012-07-26 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults.

Download or read book Strategies to Reduce Sodium Intake in the United States written by Institute of Medicine and published by National Academies Press. This book was released on 2010-11-14 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reducing the intake of sodium is an important public health goal for Americans. Since the 1970s, an array of public health interventions and national dietary guidelines has sought to reduce sodium intake. However, the U.S. population still consumes more sodium than is recommended, placing individuals at risk for diseases related to elevated blood pressure. Strategies to Reduce Sodium Intake in the United States evaluates and makes recommendations about strategies that could be implemented to reduce dietary sodium intake to levels recommended by the Dietary Guidelines for Americans. The book reviews past and ongoing efforts to reduce the sodium content of the food supply and to motivate consumers to change behavior. Based on past lessons learned, the book makes recommendations for future initiatives. It is an excellent resource for federal and state public health officials, the processed food and food service industries, health care professionals, consumer advocacy groups, and academic researchers.

Download or read book Patch Clamping written by Areles Molleman and published by John Wiley & Sons. This book was released on 2003-06-13 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patch clamping is a widely applied electrophysiological technique for the study of ion channels; membrane proteins that regulate the flow of ions across cellular membranes and therefore influence the physiology of all cells. Patch Clamping aims to cover the basic principles and practical applications of this important technique. Starting with a review of the history of patch clamping, the text then goes on to cover the basic principles, platforms, equipment and environmental control, and will also include coverage of preparation types, recording modes and analysis of results. This book will explain the basic principles and practical application of patch clamp electrophysiology Written in a non-technical style to ensure its broad appeal to novice users Takes a practical approach This self-contained guide provides everything a practising patch clamp electrophysiologist needs to know to master this technique, including an overview of membrane biophysics, standard experimental design, data analysis, and technical concerns