Download or read book Chitosan Based Systems for Biopharmaceuticals written by Bruno Sarmento and published by John Wiley & Sons. This book was released on 2012-02-16 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chitosan is a linear polysaccharide commercially produced by the deacetylation of chitin. It is non-toxic, biodegradable, biocompatible, and acts as a bioadhesive with otherwise unstable biomolecules - making it a valuable component in the formulation of biopharmaceutical drugs. Chitosan-Based Systems for Biopharmaceuticals provides an extensive overview of the application of chitosan and its derivatives in the development and optimisation of biopharmaceuticals. The book is divided in four different parts. Part I discusses general aspects of chitosan and its derivatives, with particular emphasis on issues related to the development of biopharmaceutical chitosan-based systems. Part II deals with the use of chitosan and derivatives in the formulation and delivery of biopharmaceuticals, and focuses on the synergistic effects between chitosan and this particular subset of pharmaceuticals. Part III discusses specific applications of chitosan and its derivatives for biopharmaceutical use. Finally, Part IV presents diverse viewpoints on different issues such as regulatory, manufacturing and toxicological requirements of chitosan and its derivatives related to the development of biopharmaceutical products, as well as their patent status, and clinical application and potential. Topics covered include: chemical and technological advances in chitins and chitosans useful for the formulation of biopharmaceuticals physical properties of chitosan and derivatives in sol and gel states absorption promotion properties of chitosan and derivatives biocompatibility and biodegradation of chitosan and derivatives biological and pharmacological activity of chitosan and derivatives biological, chemical and physical compatibility of chitosan and biopharmaceuticals approaches for functional modification or crosslinking of chitosan use of chitosan and derivatives in conventional biopharmaceutical dosage forms manufacture techniques of chitosan-based microparticles and nanoparticles for biopharmaceuticals chitosan and derivatives for biopharmaceutical use: mucoadhesive properties chitosan-based systems for mucosal delivery of biopharmaceuticals chitosan-based delivery systems for mucosal vaccination chitosan-based nanoparticulates for oral delivery of biopharmaceuticals chitosan-based systems for ocular delivery of biopharmaceuticals chemical modification of chitosan for delivery of DNA and siRNA target-specific chitosan-based nanoparticle systems for nucleic acid delivery functional PEGylated chitosan systems for biopharmaceuticals stimuli-sensitive chitosan-based systems for biopharmaceuticals chitosan copolymers for biopharmaceuticals application of chitosan for anti-cancer biopharmaceutical delivery chitosan-based biopharmaceuticals scaffolds in tissue engineering and regenerative medicine wound healing properties of chitosan and its use in wound dressing biopharmaceuticals toxicological properties of chitosan and derivatives for biopharmaceutical applications regulatory status of chitosan and derivatives patentability and intellectual property issues quality control and good manufacturing practice preclinical and clinical use of chitosan and derivatives for biopharmaceuticals Chitosan-Based Systems for Biopharmaceuticals is an important compendium of fundamental concepts, practical tools and applications of chitosan-based biopharmaceuticals for researchers in academia and industry working in drug formulation and delivery, biopharmaceuticals, medicinal chemistry, pharmacy, bioengineering and new materials development.
Download or read book Chitosan for Biomaterials IV written by R. Jayakumar and published by Springer Nature. This book was released on 2021-08-29 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the recent developments on the biomedical applications of chitosan and its derivatives. Chitosan exhibits unique properties such as non-toxicity, biodegradability and biocompatibility. Since its chemical structure and properties can be easily modified, it can be an ideal candidate as a biomaterial. Consequently, chitosan and its derivatives are being developed in different forms such as nanoparticles, micelles, nanofibers, hydrogels, films and 3D porous materials for various biomedical applications, ranging from drug and gene delivery to tissue engineering and regenerative medicine. The chapters of this volume focus on the potential use of chitosan and its derivatives as a hemostatic agent, tissue sealants, tissue engineering scaffolds, delivery carriers for bioactive molecules in bone tissue engineering and wound dressings. Some chapter’s deal with recent advancements of chitosan-based biomaterials as a drug, gene and transdermal drug delivery carrier. In addition, the volume focusses on the prospects of chitosan-based systems for the treatment of cancer, eye and other infectious diseases. The volume will be of interest to material scientists, chemists and biotechnologists by providing a better understanding of the physicochemical and biological characteristics of chitosan and its derivatives to develop more appropriate and innovative chitosan-based materials modified for unlimited practical applications in biomedical fields.
Download or read book Chitosan Based Hydrogels written by Kangde Yao and published by CRC Press. This book was released on 2016-04-19 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to their unique properties, chitosan-based materials have emerged as useful resources in a variety of medicines, drug controlled-release carriers, tissue engineering scaffolds, and immobilized enzymes. But many of these materials have yet to reach the commercial market. Therefore, more work must be completed to fill the gap between research and
Download or read book Chitosan and Its Derivatives as Promising Drug Delivery Carriers written by M. Prabaharan and published by Momentum Press. This book was released on 2012-10-19 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chitosan, a natural based polymer obtained by alkaline deacetylation of chitin, is non-toxic, biocompatible, and biodegradable. These properties make chitosan a good candidate for the development of conventional and novel drug delivery systems. Recently, there has been a growing interest in the chemical modification of chitosan in order to improve its solubility and widen its applications. Chemical modification of chitosan is useful for the association of bioactive molecules to the polymer and controlling the drug release profile. Chemical modification will introduce desired properties and enlarge the field of the potential applications of chitosan with the choice of various types of side chains. In this monograph, recent studies on the various types of chitosan microspheres are discussed from the viewpoint of drug delivery applications. Moreover, different types of chitosan derivatives developed as controlled drug delivery carriers and their preparation methods are discussed in detail. The modifications discussed here include amphiphilic chitosan derivatives, N-(aminoalkyl) chitosan, carboxymethyl chitosan, thiolated chitosans, phosphorylated chitosan, etc. Special emphasis has been given to the development of chitosan-based polyelectrolyte complexes, graft copolymerized chitosan and chitosan-based stimuli-responsive hydrogels as drug delivery carriers. The reviewed studies lead to the conclusion that chitosan derivatives are promising materials for the controlled delivery of various types of therapeutic agents.
Download or read book Chitosan for Biomaterials IV written by R. Jayakumar and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the recent developments on the biomedical applications of chitosan and its derivatives. Chitosan exhibits unique properties such as non-toxicity, biodegradability and biocompatibility. Since its chemical structure and properties can be easily modified, it can be an ideal candidate as a biomaterial. Consequently, chitosan and its derivatives are being developed in different forms such as nanoparticles, micelles, nanofibers, hydrogels, films and 3D porous materials for various biomedical applications, ranging from drug and gene delivery to tissue engineering and regenerative medicine. The chapters of this volume focus on the potential use of chitosan and its derivatives as a hemostatic agent, tissue sealants, tissue engineering scaffolds, delivery carriers for bioactive molecules in bone tissue engineering and wound dressings. Some chapter's deal with recent advancements of chitosan-based biomaterials as a drug, gene and transdermal drug delivery carrier. In addition, the volume focusses on the prospects of chitosan-based systems for the treatment of cancer, eye and other infectious diseases. The volume will be of interest to material scientists, chemists and biotechnologists by providing a better understanding of the physicochemical and biological characteristics of chitosan and its derivatives to develop more appropriate and innovative chitosan-based materials modified for unlimited practical applications in biomedical fields.
Download or read book Functional Chitosan written by Sougata Jana and published by Springer Nature. This book was released on 2020-03-05 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thanks to their unique properties, chitosan and chitosan-based materials have numerous applications in the field of biomedicine, especially in drug delivery. This book examines biomedical applications of functional chitosan, exploring the various functions and applications in the development of chitosan-based biomaterials. It also describes the chemical structure of chitosan and discusses the relationship between their structure and functions, providing a theoretical basis for the design of biomaterials. Lastly, it reviews chemically modified and composite materials of chitin and chitosan derivatives for biomedical applications, such as tissue engineering, nanomedicine, drug delivery, and gene delivery.
Download or read book Chitosan Based Biomaterials Volume 2 written by Jessica Amber Jennings and published by Woodhead Publishing. This book was released on 2016-09-28 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chitosan Based Biomaterials: Tissue Engineering and Therapeutics, Volume 2, provides the latest information on chitosan, a natural polymer derived from the marine material chitin. Chitosan displays unique properties, most notably biocompatibility and biodegradability. It can also be easily tuned to modify its structure or properties, making chitosan an excellent candidate as a biomaterial. Consequently, chitosan is being developed for many biomedical functions, ranging from tissue engineering and implant coatings to drug and gene delivery. This book provides readers with a full coverage of the applications of chitosan-based biomaterials. - Presents specific focus on tissue engineering and therapeutics - Provides comprehensive treatment of all biomaterial applications of chitosan - Contains contributions by leading researchers with extensive experience in the material
Download or read book Chitosan Based Biomaterials Volume 1 written by Jessica Amber Jennings and published by Woodhead Publishing. This book was released on 2016-09-26 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chitosan Based Biomaterials: Fundamentals, Volume 1, provides the latest information on chitosan, a natural polymer derived from the marine material chitin. Chitosan displays unique properties, most notably biocompatibility and biodegradability. It can also be easily tuned to modify its structure or properties, making chitosan an excellent candidate as a biomaterial. Consequently, chitosan is being developed for many biomedical functions, ranging from tissue engineering and implant coatings to drug and gene delivery. This book looks at the fundamentals of chitosan-based biomaterials. - Contains specific focus on the techniques and technologies needed to develop chitosan for biomedical applications - Presents a comprehensive treatment of the fundamentals - Provides contributions from leading researchers with extensive experience in chitosan
Download or read book Chitosan written by Shakeel Ahmed and published by John Wiley & Sons. This book was released on 2017-09-14 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unique book presenting the latest advancements and applications of chitosan-based hydrogels and composite materials in biotechnology, environmental studies, food, medicine, water treatments, drug delivery. This book delves deeply in to the preparation, characterization and multiple applications of chitin and chitosan. The 17 chapters written by leading experts is an excellent reference source and state-of-the-art review for researchers and scientists using chitosan or biopolymers in their respective areas. This book is divided into following sections: Production and derivatives of chitosan Chitosan in the textile and food industries Chitosan in biomedical applications Chitosan in agriculture and water treatment The book is practical and readers will be able to see descriptions of chitosan production methods as well as techniques that can be used to estimate and modify their physical and chemical properties. It provides a full description not only of the traditional and recent developments in the applications of chitosan in the fields of biotechnology, environmental studies, food, medicine, water treatments, drug delivery, but it includes all of the therapeutic usages as well.
Download or read book Chitosan in Biomedical Applications written by Md Saquib Hasnain and published by Academic Press. This book was released on 2021-12-01 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chitosan in Biomedical Applications provides a thorough insight into the complete chitosan chemistry, collection, chemical modifications, characterization and applications of chitosan in biomedical applications and healthcare fields. Chitosan, a biopolymer of natural origin, has been explored for its variety of applications in biomedical research, medical diagnostic aids and material science. It is the second most abundant natural biopolymer after cellulose, and considered as an excellent excipient because of its non-toxic, stable, biodegradable properties. Several research innovations have been made on applications of chitosan in biomedical applications. The book explores key topics, such as molecular weight, degree of deacetylation, and molecular geometry, along with an emphasis on recent advances in the field written by academic, industry, and clinical researchers. Chitosan in Biomedical Applications will be of interest to those in biomedical fields including the biomaterials and tissue engineering community investigating and developing biomaterials for biomedical applications, particularly graduate students, young faculty and others exploring chitosan-based materials. - Provides methodology for the design, development and selection of chitosan in biomedical applications for particular therapeutic applications - Includes illustrations demonstrating the mechanism of biological interaction of chitosan - Discusses the regulatory aspects and demonstrates the clinical efficacy of chitosan
Download or read book Chitosan for Biomaterials I written by R. Jayakumar and published by Springer. This book was released on 2011-08-10 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymeric Nanoparticles of Chitosan Derivatives as DNA and siRNA Carriers, by Y. K. Kim, H. L. Jiang, Y. J. Choi, I. K. Park, M. H. Cho and C. S. Cho.- Chitosan and Its Derivatives for Drug Delivery Perspective, by T. A. Sonia and C. P. Sharma.- Chitosan-based Nanoparticles in Cancer Therapy, by V.-K. Lakshmanan, K. S. Snima, J. D. Bumgardner, S. V. Nair, and R. Jayakumar.- Chitosan and Thiolated Chitosan, by F. Sarti and A. Bernkop-Schnürch.- Chitosan-Based Particulate Systems for Non-Invasive Vaccine Delivery, by S. Şenel.- Multifunctional Chitosan Nanoparticles for Tumor Imaging and Therapy, by J. Y. Yhee, Heebeom Koo, Dong Eun Lee, Kuiwon Choi, Ick Chan Kwon and Kwangmeyung Kim.- Chitosan-Coated Iron Oxide Nanoparticles for Molecular Imaging and Drug Delivery, by H. Arami, Z. Stephen, O. Veiseh and M. Zhang.- Chitosan: Its Applications in Drug-Eluting Devices, by Mei -Chin Chen, Fwu -Long Mi, Zi -Xian Liao and Hsing -Wen Sung.-
Download or read book Chitosan Based Nanostructures written by Faisal A. Bughdadi and published by LAP Lambert Academic Publishing. This book was released on 2013 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlighted the use of chitosan nanostructures in drug delivery, which facilitate the ability of the drug to cross the biological barriers. Chitosan has the desired properties for safe use as a pharmaceutical excipient. This has prompted accelerated research activities worldwide on chitosan nanoparticles as drug delivery vehicles. These systems have great utility in controlled release and targeting studies of almost all class of bioactive molecules as discussed in this book. Recently, chitosan is also extensively explored in gene delivery. However, studies toward optimization of process parameters and scale up from the laboratory to pilot plant and then, to production level are yet to be undertaken. Majority of studies carried out so far are only in vitro conditions. More in vivo studies need to be carried out. Chemical modifications of chitosan are important to get the desired physicochemical properties such as solubility, hydrophilicity, etc. The published literature indicates that in the near future, chitosan-based particulate systems will have more commercial status in the market than in the past.
Download or read book Chitin and Chitosan Based Biocomposites for Food Packaging Applications written by Jissy Jacob and published by CRC Press. This book was released on 2020-03-06 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chitin is one of the most important biopolymers, synthesized by an enormous number of living organisms and is a promising bioactive polymer for food packaging applications due to its functional properties. This book focuses on composition, properties, characterization, and theoretical approach of chitin and chitosan bio-composites. It describes the most recent studies concerning chitin and chitosan-based films and gives an overview about future trends regarding the industrial applications of chitin and chitosan for food packaging purposes. This book is especially useful for researchers in the fields of bionanocomposites, especially those with an interest in packaging applications.
Download or read book Chitosan Based Materials and its Applications written by Sergio Paulo Campana-Filho and published by Bentham Science Publishers. This book was released on 2017-06-07 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents 10 reviews contributed by eminent researchers around the world on chitosan based materials. The introductory chapters present information on general characteristics of chitosan and various types of materials which are based on it such as nanofibers, nanoparticles, nanocapsules and other chemically modified chitosans. This is followed by an explanation of chitosan characterization and extraction techniques. Concluding chapters describe the applications of chitosan products in water treatment, drug delivery, edible films and pervaporation membranes. Readers will therefore gain an understanding about chitosan and materials derived from this polymer and their practical applications. The volume serves as a simple reference for chemical engineering students and professionals interested in the basic and applied chemistry of chitosan and chitosan-derived products.
Download or read book Chitosan Based Nanomaterials in Plant Growth and Protection written by Vinod Saharan and published by Springer. This book was released on 2016-07-13 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brief describes various methods of chitosan nano-materials synthesis, with detailed discussion of various factors effecting its synthesis process, stability and physicochemical properties. Chitosan is naturally occurring biopolymer derived from chitin. Due to the unique biological properties of chitosan nano-materials such as antimicrobial, plant growth inducer, plant defense modulator, chitosan has gained attention in fields of plant sciences. Book further extended the details of different types of chitosan nano-materials specially for plant applications along with its future prospects in plant protection and growth. Bioactivities of chitosan nano-materials and its mechanism have also been covered. This book aims to widening the understanding of the synthesis, characterization and use of chitosan based nano-materials in plant system.
Download or read book Multifaceted Carboxymethyl Chitosan Derivatives Properties and Biomedical Applications written by R. Jayakumar and published by Springer Nature. This book was released on 2023-12-25 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited collection deals with the structure-property relationships and biomedical applications of carboxymethyl chitosan derivatives in different fields. Readers will detailed overview of the preparatory methods involved in the derivatives of carboxymethyl chitosan and its interaction with metal ions. The chapters provide a detailed overview of the different types of carboxymethyl chitosan derivatives, including the preparatory methods involved, the interactions with metal ions, and the antimicrobial activities. These different forms of carboxymethyl chitosan derivatives are found to be potentially used in food packaging, in enhancing saltiness, as biosensors, and also as wound dressing. Chapters are also devoted to the fabrication and biomedical applications of carboxymethyl chitosan derivatives-based nanofibers as well as the interaction of carboxymethyl chitosan with blood in blood clotting and the underlying mechanism. Contributing authors additionally explore topics related to carboxymethyl chitosan-based hydrogels, films, scaffolds, fibers, and composites. Finally, this volume presents the current challenges in developing biomedical products based on carboxymethyl chitosan derivatives. This book will be of interest not only to chemists, but to all scientists working in the fields of material/environmental science, biological science, and biomaterials. These chapters are great resources for any researcher who works with structure-property relationships, biological interactions, and the applications of carboxymethyl chitosan derivatives in different biomedical fields.
Download or read book Chitosan Nanocomposites written by Sarat Kumar Swain and published by Springer Nature. This book was released on 2023-04-12 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents chitosan and chitosan-based nanocomposites and their extensive applications in medical science. Utilization of chitosan nanostructured composites in different biomedical applications is highlighted. The book is suitable to be used as reference/textbook for studying the biological aspects of chitosan hybrid materials and their efficacy in different therapeutic applications. The important features of the book are summarized as follows: Chitosan as an overview Key biological aspects of chitosan-based nanocomposites Synthetic techniques for fabrication of chitosan nanocomposites for biomedical applications Designing of chitosan-based smart materials for release of therapeutics Fabrication of nanostructured chitosan-based devices for diagnosis and sensing applications Chitosan nanocomposites for regenerative applications Medicinal and therapeutic efficacy of chitosan-based hybrid materials.
