Download or read book Chirotechnology written by Roger A. Sheldon and published by CRC Press. This book was released on 1993-05-27 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference provides an introduction to the phenomenon of chirality and its importance in conjunction with biological activity and offers an easy-to-read examination of practical, industrially relevant methods for the synthesis of optically active compounds.;Furnishing hands-on guidelines for the development of economically viable synthetic compounds, Chirotechnology: explains optical isomerism and stereochemistry; gives a general overview of various methods of synthesis; supplies detailed explications of specific techniques, including fermentation, crystallization, the chirality pool, enzymatic methods, and catalytic asymmetric synthesis; illustrates and compares approaches with examples taken directly from industry such as the synthesis of pharmaceuticals, agrochemicals, flavours, and fragrances; and clarifies the importance of determining which approach to use for the synthesis of particular molecules.;With over 1100 literature citations, tables and figures, Chirotechnology is a reference for chemical engineers; industrial, organic and medicinal chemists; and bioprocess technologists, as well as a text for upper-level undergraduate, graduate and continuing-education students in these disciplines.

Download or read book Catalytic Asymmetric Synthesis written by Iwao Ojima and published by John Wiley & Sons. This book was released on 2013-03-14 with total page 1043 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the previous editions "An excellent text . . . will no doubt provide the benchmark for comparative works for many years." —Journal of the American Chemical Society "An excellent state-of-the-art compilation of catalytic asymmetric chemistry . . . should be included in any chemistry reference collection." —Choice "This is a tremendous resource and an excellent read. I recommend immediate purchase." —Perkin Transactions Since this important work was first published in 1993, the field of catalytic asymmetric synthesis has grown explosively, spawning effective new methods for obtaining enantiomerically pure compounds on a large scale and stimulating new applications in diverse fields—from medicine to materials science. Catalytic Asymmetric Synthesis, Third Edition addresses these rapid changes through contributions from highly recognized world leaders in the field. This seminal text presents detailed accounts of the most important catalytic asymmetric reactions known today, and discusses recent advances and essential information on the initial development of certain processes. An excellent working resource for academic researchers and industrial chemists alike, the Third Edition features: Six entirely new chapters focusing on novel approaches to catalytic asymmetric synthesis including non-conventional media/conditions, organocatalysis, chiral Lewis and Bronsted acids, CH activation, carbon-heteroatom bond-forming reactions, and enzyme-catalyzed asymmetric synthesis A new section focusing on the important new reaction, asymmetric metathesis, in carbon-carbon bond-forming reactions Updated chapters on hydrogenation, carbon-carbon bond-forming reactions, hydrosilylations, carbonylations, oxidations, amplifications and autocatalysis, and polymerization reactions Retaining the best of its predecessors but now thoroughly up to date, Catalytic Asymmetric Synthesis, Third Edition serves as an excellent desktop reference and text for researchers and students from the upper-level undergraduates through experienced professionals in industry or academia.

Download or read book Chiral Drugs written by Cynthia A Challener and published by Routledge. This book was released on 2017-10-23 with total page 1644 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title was first published in 2001: In the early twentieth century the relevance of chirality to the pharmaceutical industry was established by the fact that one enantiomer of hyoscyamine possessed greater pharmacological activity than the other. Today, most new drugs and those under development consist of a single optically active isomer, and chirality is also becoming an issue for the agrochemical and other industries. Regulatory agencies throughout the world are currently reviewing the importance of chirality with regard to pharmaceutical and agrochemical products. New guidelines from such agencies have been key drivers for the focus on single enantiomer products in these industries. These scientific and regulatory developments have created the need for a guide for workers in the pharmaceutical and chemical industries seeking information on chiral molecules, processes, and commercially available chiral chemicals. Chiral Drugs is a comprehensive listing of over 2500 chiral drugs, classified by therapeutic class, and including structures and physical properties for each entry in the listing. Its companion volume, Chiral Intermediates, presents the same detailed information for over 4700 commercially available chiral chemicals. The 'Chiral Pool' of readily available, relatively inexpensive chiral compounds has been expanding at a rapid rate as more and more products are produced in large quantities at economical prices. New developments in various technologies for isolating, preparing, and purifying chiral materials have greatly increased the opportunities for utilizing optically pure compounds in commercial applications. Novel techniques for classical resolution, new methodologies for developing selective enzymes for biocatalysis, advances in the application of microorganisms for chemical production, and continued progress in the area of asymmetric synthesis have all contributed to the growth of this field. Part One of each book contains four chapters which provide an introduction to topics relevant to the field of chiral chemistry and includes a brief overview of chirality, a short discussion on the current market drivers in the area of chiral chemistry, and a basic presentation of the various sources and methods for obtaining chiral compounds. Part Two presents entries for over 2500 chiral drugs, classified by therapeutic class. For each main entry, the chemical name and a list of trade names and synonyms is provided; the CAS Registry Number, the European Inventory of Existing Commercial Chemical Substances (EINECS) number, and the Merck Index (12th edition) number are given when available. The physical properties, including specific rotation, of each compound are described and indicated applications are presented. The structure of nearly every compound is provided, and the manufacturers and suppliers of the compounds are also given. Indexes, including a master index of names and synonyms and an index of custom manufacturing services for production of chiral compounds, are appended. Chiral Drugs provides an introduction to the types of sources and methods currently in use for obtaining chiral molecules and is an invaluable resource for researchers in the pharmaceutical and biotechnology sectors as well as to those working in the basic biochemical sciences. Chiral Intermediates provides an introduction to the types of sources and methods currently in use for obtaining chiral molecules and is an invaluable resource for information on available chiral molecules. Chiral Intermediates and Chiral Drugs are the most comprehensive and detailed guides to chiral compounds available.

Download or read book Chiral Intermediates written by Cynthia A. Challener and published by John Wiley & Sons. This book was released on 2001-09 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the early twentieth century the relevance of chirality to the pharmaceutical industry was established by the fact that one enantiomer of hyoscyamine possessed greater pharmacological activity than the other. Today, most new drugs and those under development consist of a single optically active isomer, and chirality is also becoming an issue for the agrochemical and other industries. Regulatory agencies throughout the world are currently reviewing the importance of chirality with regard to pharmaceutical and agrochemical products. New guidelines from such agencies have been key drivers for the focus on single enantiomer products in these industries. These scientific and regulatory developments have created the need for a guide for workers in the pharmaceutical and chemical industries seeking information on chiral molecules, processes, and commercially available chiral chemicals. Chiral Intermediates presents the chemical professional with a comprehensive listing of over 4700 available chiral chemicals including specific data of interest for each entry in the listing. Its companion volume, Chiral Drugs presents the same detailed information for over 2000 chiral drugs. The 'Chiral Pool' of readily available, relatively inexpensive chiral compounds has been expanding at a rapid rate as more and more products are produced in large quantities at economical prices. New developments in various technologies for isolating, preparing, and purifying chiral materials have greatly increased the opportunities for utilizing optically pure compounds in commercial applications. Novel techniques for classical resolution, new methodologies for developing selective enzymes for biocatalysis, advances in the application of microorganisms for chemical production, and continued progress in the area of asymmetric synthesis have all contributed to the growth of this field. Part I contains four chapters which provide an introduction to topics relevant to the field of chiral chemistry and includes a brief overview of chirality, a short discussion on the current market drivers in the area of chiral chemistry, and a basic presentation of the various sources and methods for obtaining chiral compounds. Part II presents entries for 4700 commercially available chiral compounds. For each main entry, the chemical name and a list of trade names and synonyms is provided; the CAS Registry Number, the European Inventory of Existing Commercial Chemical Substances (EINECS) number, and the Merck Index (12th edition) number are given when available. The physical properties, including specific rotation, of each compound are described and indicated applications are presented. The structure of nearly every compound is provided, and the manufacturers and suppliers of the compounds are also given. Indexes, including a master index of names and synonyms and an index of custom manufacturing services for production of chiral compounds, are appended. Chiral Intermediates provides an introduction to the types of sources and methods currently in use for obtaining chiral molecules and is an invaluable resource for information on available chiral molecules. Chiral Intermediates and Chiral Drugs are the most comprehensive and detailed guides to chiral compounds available.

Download or read book Macromolecules Containing Metal and Metal Like Elements Volume 2 written by Alaa S. Abd-El-Aziz and published by John Wiley & Sons. This book was released on 2003-10-21 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal- and metalloid-containing macromolecules are defined as large molecules (i.e., polymers, DNA, proteins) that contain a metal or metalloid group affiliated with the molecule. Compiled by an all-star cast of macromolecular experts, Macromolecules Containing Metal and Metal-Like Elements, Volume 2, Organoiron-Containing Polymers: Provides useful descriptions of applications for the reader to apply in his/her research into materials, polymers, and medicine/drug development. Covers non-linear optical materials, speciality magnetic materials, liquid crystals, anticancer and antiviral drugs, treatment of arthritis, antibacterial drugs, antifouling materials, treatment of certain vitamin deficiencies, electrical conductors and semiconductors, piezoelectronic materials, electrodes, UV absorption applications, super-strength materials, special lubricants and gaskets, selective catalytic and multisite catalytic agents.

Download or read book Chirotechnology 2nd Edition written by Roger A. Sheldon and published by CRC Press. This book was released on 2007-01-15 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Macromolecules Containing Metal and Metal Like Elements Volume 4 written by Alaa S. Abd-El-Aziz and published by John Wiley & Sons. This book was released on 2005-04-15 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series provides a useful, applications-oriented forum for the next generation of macromolecules and materials. Volume 4 provides useful descriptions of Group IV metals and their applications, including silicon-, organogermanium-, organotin-, and organolead-containing polymers. A high-quality team of macromolecular experts from around the world have put together these leading macromolecule titles.

Download or read book Handbook of Chiral Chemicals written by David Ager and published by CRC Press. This book was released on 2005-10-21 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: As pharmaceutical companies look to develop single enantiomers as drug candidates, chemists are increasingly faced with the problems associated with this subclass of organic synthesis. "The Handbook of Chiral Chemicals, Second Edition" highlights the problems associated with the production of chiral compounds on a commercial scale. The handbook fir

Download or read book Business Franchise Guide written by Commerce Clearing House and published by . This book was released on 1980 with total page 1802 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book An Unfinished Agenda written by K Anji Reddy and published by Penguin UK. This book was released on 2015-01-15 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: From his birth in a village in Andhra to founding and running Dr. Reddy’s Laboratories, now one of India’s largest pharmaceutical enterprises, Dr K. Anji Reddy’s journey makes for an inspiring story. That story is told rivetingly in his own words in his memoir, An Unfinished Agenda. Dr Anji Reddy became an entrepreneur at a time when India was woefully short of technology to manufacture many basic medicines. Then, in barely three decades, the Indian pharmaceutical industry had grown to the point that India not only became self-sufficient in medicine, but also a supplier of affordable generic medicines to the world. Dr Anji Reddy provides a ringside view of this remarkable transformation, with fascinating anecdotes about those who made it happen. The history of modern medicine is a gripping story of triumphs and failures. An Unfinished Agenda takes the reader on a whirlwind tour of the science of medicine over the last hundred years and reminds us of the stark challenges that remain.

Download or read book Chirality in Industry II written by A. N. Collins and published by John Wiley & Sons. This book was released on 1998-02-04 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second volume of Chirality in Industry contains new case histories from a wide range of contributors from industry or with strong industrial connections. While it is intended that the new volume will stand on its own, Volumes I and II taken together present an up-to-date and comprehensive picture of the technologies required to produce optically active compounds on a multi-kilogramme to high tonnage scale as well as illustrating the breadth of application of these technologies; the pharmaceuticals, agrochemicals, electronics, food, flavour and fragrance industries are all represented. Chirality in Industry II All new case histories Unique industrial perspective on chiral technology Emphasis on scale-up and process development Comparison of biocatalysis, asymmetric synthesis and classical resolution approaches The chiral infrastructure is now largely in place and there is no reason why large-scale production should not be possible for even moderately priced single enantiomer products. The successful industrial application of chiral chemistry depends on the integration of a range of supporting technologies and there are many examples in this volume of how widely the industrial practitioner must cast the net to achieve practical production methods. As with Volume I, this new volume is of particular interest to those professionally involved in the scale-up processes for single enantiomers. However, students and researchers involved in a more academic pursuit of optical activity will also benefit from some of the facets of large-scale thinking. An economic solution is still most likely to be a simple, elegant solution.

Download or read book Asymmetric Catalysis from a Chinese Perspective written by Shengming Ma and published by Springer Science & Business Media. This book was released on 2011-07-06 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Qi-Lin Zhou and Jian-Hua Xie: Chiral Spiro Catalysts.- Fuk Loi Lam, Fuk Yee Kwong and Albert S. C. Chan: Chiral Phosphorus Ligands with Interesting Properties and Practical Applications.- Jiang Pan, Hui-Lei Yu, Jian-He Xu, Guo-Qiang Lin: Advances in Biocatalysis: Enzymatic Reactions and Their Applications.- Mei-Xiang Wang: Enantioselective Biotransformations of Nitriles.- Man Kin Wong, Yiu Chung Yip and Dan Yang: Asymmetric Epoxidation Catalyzed by Chiral Ketones.- W. J. Liu, N. Li and L. Z. Gong: Asymmetric Organocatalysis.- Qing-Hua Fan and Kuiling Ding: Enantioselective Catalysis with Structurally Tunable Immobilized Catalysts.- Chang-Hua Ding, Xue-Long Hou: Transition Metal-Catalyzed Asymmetric Allylation.- Jian Zhou and Yong Tang: Enantioselective Reactions with Trisoxazolines.- Xiang-Ping Hu, Duo-Sheng Wang, Chang-Bin Yu, Yong-Gui Zhou, and Zhuo Zheng: Adventure in Asymmetric Hydrogenation: Synthesis of Chiral Phosphorus Ligands and Asymmetric Hydrogenation of Heteroaromtics.

Download or read book Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 1997 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and published by . This book was released on 1996 with total page 2182 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Novel Optical Resolution Technologies written by Kenichi Sakai and published by Springer Science & Business Media. This book was released on 2007-02-15 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: After theend ofthe 20th century, the science ofcrystallizationreached a truly exciting stage where new opportunities emerged in both theory and expe- ment. Variousphysical methodsare capableofresolvingthesurface as wellas theinsidestructureofcrystalsattheatomiclevelwhilenewhigh-performance computingresourcesaffordthecapabilityofmodelingthecomplexlarge-scale alignmentsnecessarytosimulatecrystallizationinrealsystems.Asaresult,the science of crystallization has shifted gradually fromstatic to dynamic science and considerable progress now underlies the complex but beautiful cryst- lization process. I believe that if a de'nitive history of 21st century science is ever written,one of the highlightswill be the science ofcrystallization. This science has the following characteristics: in'nite advances in soph- tication, unlimited opportunities not only for intellectual excitement but also forindustrialmerit,strongcollaborationwithbiologyandmaterialscience,as wellaswithallareasofchemistry.Thevastpotentialofcrystallizationasan- portant'eld ofscience isfar beyondthesimple technologyofpharmaceutical industries during the 20th century. Optical resolution was one small area of chemistry in the last century. This was more a technology than a science, largely because trial and error was the only method to obtain good results. However, the situation is now changing. Therearesomanyappealing,hidden'ndingsintheprocessofcrystallization. Historically, crystallization began in an old laboratory in academia and then gradually shifted to industry. Now,it is making itscomeback in academia due toseveralnewresearchbranchestryingtodiscoverwhatisgoingonduringthe crystallizationprocess.Ibelieve this'eld ofscience isnowgrowingasa result of the wonderfulcoupling between industry and academia. I read a prepublication draft of Novel Optical Resolution Technologies,and foundthateachoneofthesegeneralcharacteristicsofsciencehadarealityand sharpness that I had not expected. While it was a sheer delight to revisit each of these triumphs guided by the wise insights and analyses found throughout the book. There is a good balance between the underlying historical material and the design and execution aspects of each topic.

Download or read book Functional Metal Organic Frameworks Gas Storage Separation and Catalysis written by Martin Schröder and published by Springer. This book was released on 2010-09-15 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: - Microporous Organic Polymers: Design, Synthesis, and Function By J.-X. Jiang and A. I. Cooper - Hydrogen, Methane and Carbon Dioxide Adsorption in Metal-Organic Framework Materials By X. Lin, N. R. Champness, and M. Schröder -Doping of Metal-Organic Frameworks with Functional Guest Molecules and Nanoparticles By F. Schröder and R. A. Fischer -Chiral Metal-Organic Porous Materials: Synthetic Strategies and Applications in Chiral Separation and Catalysis By K. Kim, M. Banerjee, M. Yoon, and S. Das -Controlled Polymerization by Incarceration of Monomers in Nanochannels By T. Uemura and S. Kitagawa -Designing Metal-Organic Frameworks for Catalytic Applications L. Ma and W. Lin -Magnetic and Porous Molecule-Based Materials By N. Roques, V. Mugnaini, and J. Veciana

Download or read book Chemistry of Biologically Potent Natural Products and Synthetic Compounds written by Shahid Ul-Islam and published by John Wiley & Sons. This book was released on 2021-06-29 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: In view of their promising biological and pharmaceutical activities, natural product inspired and heterocyclic compounds have recently gained a reputation in the field of medicinal chemistry. Over the past decades, intensive research efforts have been ongoing to understand the synthesis, biochemistry and engineering involved in their preparation and action mechanisms. Several novel natural product derivatives, heterocyclic and other synthetic compounds, have been reported to have shown interesting biological activities including anticancer, antimicrobial, anti-inflammatory, anti-glycemic, anti-allergy and antiviral etc. Chemistry of Biologically Potent Natural Products and Synthetic Compounds provides up-to-date information on new developments and most recent medicinal applications of the natural products and derivatives, as well as the chemistry and synthesis of heterocyclic and other related compounds.

Download or read book Biocatalytic Membrane Reactors written by Enrico Drioli and published by CRC Press. This book was released on 2020-10-07 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research level reference book has been co-written by Enrico Drioli, perhaps one of the world's best known researchers into membrane technology. The application of membrane technology to chemical transformation and molecular separation are beginning to be exploited in the pharmaceutical science and biotechnology industries, but there is a need for researchers and students to have up-to-date literature - and this book provides it. The book will be of interest to students of chemistry, chemical engineering, pharmacy and biotechnology.