Download or read book Chirality in Natural and Applied Science written by W. John Lough and published by CRC PressI Llc. This book was released on 2002 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: An understanding of chirality is central to the study and application of the molecular sciences. Particularly relevant to the work of pharmaceutical, natural product, organic, and analytical chemists, biochemists, and molecular biologists, Chirality in Natural and Applied Science provides a highly practical overview of the chemical significance of chirality. Contributions from world-class scientists describe our current understanding of chirality and discuss its significant impact on modern chemistry and molecular science. They explore the origins of chirality, its natural occurrence on a variety of scales, and its current and potential applications in research and industry. Chirality undoubtedly will remain integral to all of molecular science, and as our knowledge and understanding grow, its importance certainly will increase. Bringing together the insights and experience of scientists who have played influential roles in chirality research, Chirality in Natural and Applied Science helps ensure a thorough understanding of chirality, its importance and its applications.
Download or read book Current Topics in Chirality written by Takashiro Akitsu and published by BoD – Books on Demand. This book was released on 2021-09-01 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chirality is a concept related not only to organic chemistry but also to each field of natural science. Awareness of hierarchy is important for universal and comprehensive understanding. As such, this book examines myriad subjects related to chirality in chemistry and interdisciplinary applications. In contrast to the previous book, this new book about chirality includes contributions from authors in many fields of natural science, providing a wider overview. The book’s focus is chirality and organic chemistry, including synthesis and reactions.
Download or read book The Origin of Chirality in the Molecules of Life written by Albert Guijarro and published by Royal Society of Chemistry. This book was released on 2008 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few times an unsolved issue in science has dealt with a larger number of approaches or theories intending to shed light on it and few times this has been done from so different, often orthogonal perspectives. This book covers a hot topic, one of the unsolved problems not just in chemistry, but in science
Download or read book Chirality at the Nanoscale written by David B. Amabilino and published by John Wiley & Sons. This book was released on 2009-02-11 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only standard reference in this exciting new field combines the physical, chemical and material science perspectives in a synergic way. This monograph traces the development of the preparative methods employed to create nanostructures, in addition to the experimental techniques used to characterize them, as well as some of the surprising physical effects. The chapters cover every category of material, from organic to coordination compounds, metals and composites, in zero, one, two and three dimensions. The book also reviews structural, chemical, optical, and other physical properties, finishing with a look at the future for chiral nanosystems.
Download or read book The Origin of Chirality in the Molecules of Life 2nd Edition written by Albert Guijarro and published by Royal Society of Chemistry. This book was released on 2022-06-10 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an interdisciplinary review of one of the great unsolved mysteries that has fascinated scientists for over 150 years: the origin of chirality in biomolecules. It is fundamental, comprehensive and structured to be accessible for educational purposes.
Download or read book Amplification of Chirality written by Kenso Soai and published by Springer Science & Business Media. This book was released on 2009-11-04 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amplification of Chirality presents critical reviews of the present position and future trends in modern chemical research. The book contains short and concise reports on chemistry. Each is written by the world renowned experts. Still valid and useful after 5 or 10 years, more information as well as the electronic version of the whole content available at: springerlink.com.
Download or read book Chirality in Drug Research written by Eric Francotte and published by John Wiley & Sons. This book was released on 2007-09-24 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Divided into the three main sections of synthesis, analysis and drug development, this handbook covers all stages of the drug development process, including large-scale synthesis and purification of chirally pure pharmaceuticals. The two editors from academia and a major pharmaceutical company have assembled an experienced, international team who provide first-hand practical advice and report previously unpublished data. In the first section, the isolation of chiral drugs from natural sources, their production in enzymatic processes and the resolution of racemic mixtures in preparative chromatography are outlined in separate chapters. For the section on qualitative and quantitative analysis, enantioselective chromatographic methods are presented as well as optical methods and CE-MS, while the final section deals with the pharmacology, pharmacokinetics and metabolic aspects of chiral drugs, devoting whole chapters to stereoselective drug binding and modeling chiral drug-receptor interactions. With its unique industry-relevant aspects, this is a must for medicinal and pharmaceutical chemists.
Download or read book Chiral Analysis written by P.L. Polavarapu and published by Elsevier. This book was released on 2018-05-30 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chiral Analysis: Advances in Spectroscopy, Chromatography and Emerging Methods, Second Edition covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals, including chemistry graduate students, analytical chemists, organic chemists, professionals in the pharmaceutical industry, and others with an interest in chirality and chiral analysis. This thoroughly revised second edition covers several new, important areas of chiral analysis that have emerged since the first edition. Three of the new methods provide higher sensitivity than can be realized with the current methods and are expected to become mainstream applications: cavity based methods offer vastly higher sensitivity than conventional polarimetric methods, microwave chiral detection provides unsurpassed sensitivity for identifying diastereomers, and the rotating electric field method offers a competing new approach for the separation of enantiomers. Another topic, chirality in extraterrestrial life, has not been discussed in any other book and is important for understanding the origin of life. Offers the only book to cover both spectroscopic and separation methods in a single volume Provides an up-to-date and detailed review of the various techniques available, including new techniques that have emerged since the first edition Includes contributions from a range of leading experts in the field, now edited by award-winning chirality researcher Prasad Polavarapu
Download or read book Organometallic Chirality written by Gyula Pályi and published by Mucchi Editore. This book was released on 2008 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mirror Image Asymmetry written by James P. Riehl and published by John Wiley & Sons. This book was released on 2010-03-22 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the importance and consequences of asymmetry from molecules to the macroscopic world As scientists have become more capable of probing the structure of three-dimensional objects at the molecular level, the need to understand the concept and the consequences of mirror-image asymmetry—chirality—has increased enormously. Written at an introductory level, Mirror-Image Asymmetry provides an overview of the importance and effects of asymmetry from the atomic and molecular world of physics and chemistry to the organisms and structures that we see and use in our everyday life. The reader will develop a broad appreciation of three-dimensional asymmetry from the microscopic molecular world to the macroscopic world of handedness, automobile driving, windmills, sports, and similar phenomena. The book features: An introduction to basic definitions and the nomenclature of asymmetric and dissymmetric molecules Up-to-date examples of the importance and consequences of asymmetry in modern drug applications, current theories of the origin of asymmetry in nature, and examples of molecular asymmetry in smell, taste, and insect communication Many illustrations, chemical structures, and photographs that enable the reader to connect the actual asymmetrical structures to the different phenomena that depend on structural asymmetry In the 150 years since Louis Pasteur discovered asymmetry in molecular structures, scientists have made great progress in understanding how interactions between chiral molecules influence biochemical processes. This knowledge is leading to very sophisticated asymmetric synthetic techniques that have greatly benefitted many research groups especially those in the pharmaceutical industry. This guide to the role of molecular and macroscopic chirality will inspire students and scientists in chemistry, biology, physics, and drug discovery.
Download or read book Lectures in Astrobiology written by Muriel Gargaud and published by Springer Science & Business Media. This book was released on 2005-06-08 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: First comprehensive, beginning graduate level book on the emergent science of astrobiology.
Download or read book Chirality in Drug Design and Development written by Indra K. Reddy and published by CRC Press. This book was released on 2004-03-15 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering every essential element in the development of chiral products, this reference provides a solid overview of the formulation, biopharmaceutical characteristics, and regulatory issues impacting the production of these pharmaceuticals. It supports researchers as they evaluate the pharmacodynamic, pharmacokinetic, and toxicological characteristics of specific enantiomers and chiral drug compounds and addresses in one convenient reference all the major challenges pertaining to drug chirality that have been neglected in the literature. Chirality in Drug Design and Development collects the latest studies from an interdisciplinary team of experts on chiral drug design.
Download or read book Chiral Separation Techniques written by Ganapathy Subramanian and published by John Wiley & Sons. This book was released on 2008-01-08 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised, with either entirely new or completely updated contents, this is a practical manual for the small and large-scale preparation of enantiomerically pure products. The result is a vital resource for meeting the highest purity standards in the manufacture of chiral pharmaceuticals, food additives and related compounds. All the approaches covered here are highly relevant to modern manufacturing and quality control schemes in the pharmaceutical and biotech industries, addressing the increasingly important issue of drug safety in view of tougher regulatory standards worldwide.
Download or read book Possible Scenarios for Homochirality on Earth written by Michiya Fujiki and published by Buy this from MDPI Books. This book was released on 2019-11-14 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1978, Fred Hoyle proposed that interstellar comets carrying several viruses landed on Earth as part of the panspermia hypotheses. With respect to life, the origin of homochirality on Earth has been the greatest mystery because life cannot exist without molecular asymmetry. Many scientists have proposed several possible hypotheses to answer this long-standing L-D question. Previously, Martin Gardner raised the question about mirror symmetry and broken mirror symmetry in terms of the homochirality question in his monographs (1964 and 1990). Possible scenarios for the L-D issue can be categorized into (i) Earth and exoterrestrial origins, (ii) by-chance and necessity mechanisms, and (iii) mirror-symmetrical and non-mirror-symmetrical forces as physical and chemical origins. These scenarios should involve further great amplification mechanisms, enabling a pure L- or D-world.
Download or read book Handbook of Chiral Chemicals written by David Ager and published by CRC Press. This book was released on 2005-10-21 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: As pharmaceutical companies look to develop single enantiomers as drug candidates, chemists are increasingly faced with the problems associated with this subclass of organic synthesis. "The Handbook of Chiral Chemicals, Second Edition" highlights the problems associated with the production of chiral compounds on a commercial scale. The handbook fir
Download or read book Chiral Pollutants written by Imran Ali and published by John Wiley & Sons. This book was released on 2005-07-15 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today, among the various chiral discrimination methods, chromatography and capillary electrophoresis techniques have become powerful tools in environmental analysis. Therefore, there is a need to describe the art of the determination of the chiral pollutants in the environmental matrices. This book provides the complete information on the types of the chiral pollutants, their toxicities and methods of determination by chromatography and capillary electrophoresis.
Download or read book Insights into the Chemistry of Organic Structure Directing Agents in the Synthesis of Zeolitic Materials written by Luis Gómez-Hortigüela and published by Springer. This book was released on 2018-03-31 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume focuses on the host-guest chemistry of organic molecules and inorganic systems during synthesis (structure-direction). Organic molecules have been used for many years in the synthesis of zeolitic nanoporous frameworks. The addition of these organic molecules to the zeolite synthesis mixtures provokes a particular ordering of the inorganic units around them that directs the crystallization pathway towards a particular framework type; hence they are called structure-directing agents. Their use has allowed the discovery of an extremely large number of new zeolite frameworks and compositions. This volume covers the main aspects of the use of organic molecules as structure-directing agents for the synthesis of zeolites, including first an introduction of the main concepts, then two chapters covering state-of-the-art techniques currently used to understand the structure-directing phenomenon (location of molecules by XRD and molecular modeling techniques). The most recent trends in the types of organic molecules used as structure-directing agents are also presented, including the use of metal-complexes, the use of non-ammonium-based molecules (mainly phosphorus-based compounds) and the role of supramolecular chemistry in designing new large organic structure-directing agents produced by self-aggregation. In addition the volume explores the latest research attempting to transfer the asymmetric nature of organic chiral molecules used as structure-directing agents to the zeolite lattice to produce chiral enantioselective frameworks, one of the biggest challenges today in materials chemistry. This volume has interdisciplinary appeal and will engage scholars from the zeolite community with a general interest in microporous materials, which involves not only zeolite scientists, but also researchers working on metal-organic framework materials. The concepts covered will also be of interest for researchers working on the application of materials after encapsulation of molecules of interest in post-synthetic treatments. Further the work explores the main aspects of host-guest chemistry in hybrid organo-inorganic templated materials, which covers all types of materials where organic molecules are used as templates and are confined within framework-structured inorganic materials (intercalation compounds). Therefore the volume is also relevant to the wider materials chemistry community.
