Download or read book Chiral Recognition Analysis of Bio molecules by Electrospray Ionization and Matrix Assisted Laser Desorption ionization Mass Spectrometry written by Mingfeng Bai and published by . This book was released on 2003 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Development of Matrix assisted Laser Desorption ionization and Liquid Chromatography Electrospray Ionization Based Mass Spectrometric Techniques for Characterizing and Quantifying Endogenous and Therapeutic Biomolecules written by Bingming Chen and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endogenous biomolecules, such as neuropeptide, protein and carbohydrates, play important roles in biological and physiological processes. Over the last two decades, therapeutic biomolecules, including therapeutic peptides, proteins and monoclonal antibodies, have become large and fast-growing segments of the pharmaceutical industry. However, analyzing biomolecules is challenging due to their large size, complex structure and various modifications. In situ analysis of biomolecules is even more challenging due to the large dynamic range and complex microenvironments on tissue surface. In this dissertation, matrix-assisted laser desorption/ionization (MALDI) and liquid chromatography (LC) -- electrospray ionization (ESI) based mass spectrometric techniques were developed to characterize and quantify endogenous and therapeutic biomolecules. Specifically, this work developed novel ionization techniques and mass spectrometry imaging workflows to study the sequence and in situ distribution of biomolecules on high resolution accurate mass instrument platforms. Moreover, absolute or relative quantifications of biomolecules, such as therapeutic peptide or N-glycans, were measured by cutting-edge quantification workflows. In summary, this work not only improves current analytical methodology for characterizing biomolecules, but also demonstrates its potential applications in pharmaceutical industry and clinical settings.
Download or read book Analysis of Biomolecules by Matrix assisted Laser Desorption ionization fourier Transform Mass Spectrometry written by Anissa Wai-Sinn Wong and published by . This book was released on 1998 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Studies of Bio active Molecules by Matrix Assisted Laser Desorption ionization and Electrospray Ionization Mass Spectrometry written by Ying Cheng and published by . This book was released on 2000 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in MALDI and Laser Induced Soft Ionization Mass Spectrometry written by Rainer Cramer and published by Springer. This book was released on 2016-08-23 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation and large-scale, high-speed MS sample profiling, new methods based on MALDI or MALDI-like sample preparations, and the advantages of ESI to MALDI MS analysis. This is an ideal book for graduate students and researchers in the field of bioanalytical sciences. This book also: • Showcases new techniques and applications in MALDI MS • Demonstrates how MALDI is preferable to ESI (electrospray ionization) • Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and the various application areas, such as cancer proteomics
Download or read book Applications of MALDI TOF Spectroscopy written by Zongwei Cai and published by Springer. This book was released on 2014-07-08 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: MALDI-ToF Mass Spectrometry for Studying Noncovalent Complexes of Biomolecules, by Stefanie Mädler, Elisabetta Boeri Erba, Renato Zenobi Application of MALDI-TOF-Mass Spectrometry to Proteome Analysis Using Stain-Free Gel Electrophoresis, by Iuliana Susnea, Bogdan Bernevic, Michael Wicke, Li Ma, Shuying Liu, Karl Schellander, Michael Przybylski MALDI Mass Spectrometry for Nucleic Acid Analysis, by Xiang Gao, Boon-Huan Tan, Richard J. Sugrue, Kai Tang Determination of Peptide and Protein Disulfide Linkages by MALDI Mass Spectrometry, by Hongmei Yang, Ning Liu, Shuying Liu MALDI In-Source Decay, from Sequencing to Imaging, by Delphine Debois, Nicolas Smargiasso, Kevin Demeure, Daiki Asakawa, Tyler A. Zimmerman, Loïc Quinton, Edwin De Pauw Advances of MALDI-TOF MS in the Analysis of Traditional Chinese Medicines, by Minghua Lu, Zongwei Cai Chemical and Biochemical Applications of MALDI TOF-MS Based on Analyzing the Small Organic Compounds, by Haoyang Wang, Zhixiong Zhao, Yinlong Guo Bioinformatic Analysis of Data Generated from MALDI Mass Spectrometry for Biomarker Discovery, by Zengyou He, Robert Z. Qi, Weichuan Yu
Download or read book Electrospray assisted Laser Desorption Ionization Mass Spectrometry for Proteomic Studies written by Ivory Xingyu Peng and published by . This book was released on 2009 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Analysis of Biomolecules Using Matrix assisted Laser Desorption ionization Mass Spectrometry written by Jennifer Ann Firestine and published by . This book was released on 2000 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Application of Matrix assisted Laser Desorption ionization Time of flight Mass Spectrometry to the Study of Bacterial Biomolecules written by Teresa Catherine Cain and published by . This book was released on 1997 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biochemical and Biotechnological Applications of Electrospray Ionization Mass Spectrometry written by A. Peter Snyder and published by . This book was released on 1996 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents new ways of creating ions of polar and labile biopolymeric species with remarkable ease and efficiency. Introduces better characterization of proteins and other biological molecules. Presents major fundamental issues in such areas as immunology, biochemistry, and natural toxins. Demonstrates methods used to resolve the data from various biological process investigations into useful information. Provides an application-driven approach, presenting valuable insights into the experiments in the volume.
Download or read book Matrix assisted Laser Desorption ionization Mass Spectrometric Study of Biologic Molecules written by Yan-Hui Liu and published by . This book was released on 1996 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Matrix Assisted Laser Desorption Ionization with External Source Quadrupole Fourier Transform Mass Spectrometry for the Analysis of Biomolecules written by Steven Travis Fannin and published by . This book was released on 1995 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Development of Electrospray Ionization Mass Spectrometry for Direct Analysis of Complex Samples and an Investigation of Ionization Mechanism of Matrix assisted Laser Desorption ionization Mass Spectrometry written by Haixing Wang and published by . This book was released on 2014 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mass Spectrometry Handbook written by Mike S. Lee and published by John Wiley & Sons. This book was released on 2012-04-16 with total page 1362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to its enormous sensitivity and ease of use, mass spectrometry has grown into the analytical tool of choice in most industries and areas of research. This unique reference provides an extensive library of methods used in mass spectrometry, covering applications of mass spectrometry in fields as diverse as drug discovery, environmental science, forensic science, clinical analysis, polymers, oil composition, doping, cellular research, semiconductor, ceramics, metals and alloys, and homeland security. The book provides the reader with a protocol for the technique described (including sampling methods) and explains why to use a particular method and not others. Essential for MS specialists working in industrial, environmental, and clinical fields.
Download or read book Methods and Mechanisms for Producing Ions from Large Molecules written by K.G. Standing and published by Springer. This book was released on 1991 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: A NATO Advanced Research Workshop on Methods and Mechanisms for Producing Ions from Large Molecules was held at Minaki Lodge, Minaki, Ontario, Canada, from 24 to 28 June 1990. The workshop was hosted by the time-of-flight group of the Department of Physics at the University of Manitoba, and was attended by 64 invited participants from around the world. Twenty-nine invited talks were given and 19 papers were presented as posters. Of the 48 contributions, 38 are included in these proceedings. The conference was organized to study the rapidly changing field of mass spectrometry of biomolecules. Particle-induced desorption (especially with MeV particles) has been the most effective method of producing molecular ions from biomolecules. An important part of the workshop was devoted to recent developments in this field, particularly to progress in understanding the fundamentals of the desorption process. In this respect, the meeting was similar to previous conferences in Marburg, FRG (1978); Paris, F (1980); Uppsala, S (1981); College Station, USA (1983,1984); Wangerooge, FRG (1986); Orsay, F (1988); Spiekeroog, FRG (1989); and to the IFOS series of meetings at Munster, FRG (1981,1983,1985,1987) and L6vAnger, S (1989). As in the most recent of these meetings, there was some emphasis on new developments, particularly cluster bombardment. A departure from the concentration on particle bombardment processes at this conference was inspired by the dramatic results obtained with two new methods for producing molecular ions from large molecules: matrix-assisted laser desorption and electrospray.
Download or read book Matrix assisted Laser Desorption Ionization Mass Spectrometry of Biomolecules written by Chau-Wen Chou and published by . This book was released on 1996 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ionization Methods in Organic Mass Spectrometry written by Alison E Ashcroft and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ionization Methods in Organic Mass Spectrometry is a basic practical guide for scientists of all disciplines who wish to analyse samples by organic mass spectrometry. Concentrating on instrumental operation, this book gives step-by-step instructions on how to set up, and how to achieve the best results, using a range of ionization methods, including atmospheric pressure chemical ionization, electrospray ionization and matrix assisted laser desorption ionization. Ionization Methods in Organic Mass Spectrometry will enable a beginner, or practitioner with limited experience, to choose the most appropriate ionization technique in application areas such as biomolecules, drugs and metabolites, pesticides, polymers and many other organic compounds. It will be a valuable practical guide for technicians, graduates, students or researchers - or indeed anyone new to practical organic mass spectrometry.
