Download or read book Chimera Research written by Insoo Hyun and published by Humana. This book was released on 2020-08-14 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume addresses challenging new questions surrounding stem cell-based chimera research. This book is organized into three parts: Part One provides readers with a summary of different human donor cell types. The chapters in this section discuss ways to evaluate new types of pluripotent stem cells; the derivation of naïve and primed pluripotent stem cells from mouse preimplantation embryos; and the ethical and regulatory complexities of informed consent for the procurement of somatic cells. Part Two discusses methods for generating chimeras. The chapters here look at chick models and human-chick organizer grafts; generating human-pig interspecies chimeras; and techniques for transplanting mouse neural stem cells into a mouse disease model for stroke. Part Three concludes the book with a look at ongoing ethical controversies and new scientific directions. Chapters in this part cover the ethics of crossing the xenobarrier; animal welfare; experimentation with spermatogonial stem cells; and cautious approaches to human-monkey chimera studies to further understand complex human brain disorders. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Chimera Research: Methods and Protocols is a valuable resource for scientists interesting in using chimeras as a research tool while also taking into consideration their complex ethical scopes.
Download or read book Dictionary of Global Bioethics written by Henk ten Have and published by Springer Nature. This book was released on 2021-05-26 with total page 1063 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Dictionary presents a broad range of topics relevant in present-day global bioethics. With more than 500 entries, this dictionary covers organizations working in the field of global bioethics, international documents concerning bioethics, personalities that have played a role in the development of global bioethics, as well as specific topics in the field.The book is not only useful for students and professionals in global health activities, but can also serve as a basic tool that explains relevant ethical notions and terms. The dictionary furthers the ideals of cosmopolitanism: solidarity, equality, respect for difference and concern with what human beings- and specifically patients - have in common, regardless of their backgrounds, hometowns, religions, gender, etc. Global problems such as pandemic diseases, disasters, lack of care and medication, homelessness and displacement call for global responses.This book demonstrates that a moral vision of global health is necessary and it helps to quickly understand the basic ideas of global bioethics.
Download or read book CHIMBRIDS Chimeras and Hybrids in Comparative European and International Research written by Jochen Taupitz and published by Springer Science & Business Media. This book was released on 2009-10-15 with total page 1032 pages. Available in PDF, EPUB and Kindle. Book excerpt: National, European and international concepts and strategies concerning the legal and ethical framework of chimera and hybrid research are still largely missing, even though they are absolutely necessary in order to use the potential of chimera and hybrid research effectively and efficiently for the benefit of science and society. The outcome of the CHIMBRIDS-Project successfully sheds light on the chances and risks of this research and provides legal solutions to existing problems in order to help decision-makers fulfil their tasks in an informed and efficient manner. This comprehensive volume details the complete results, contributed by 40 scholars from 10 member states of the European Union, Canada, China, Israel, Japan, Switzerland and the US, with descriptive reports of the legal situation in specific countries and in-depth analysis of all scientific, medical, ethical and legal implications of chimera and hybrid research.
Download or read book Exploring the Ethics of Organ Farming Interspecies Chimera An Overview written by Dr. Hakim Saboowala and published by Dr.Hakim Saboowala. This book was released on 2020-04-28 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exploring the Ethics of Organ Farming & Interspecies Chimera. An Overview. An attempt has been made in this overview to examine the ethical issues surrounding human-animal chimeras and their use in the production of organs for transplantation. Currently, there is a prodigious backlog of transplants in the United States. · The median wait time for an organ transplant is almost 5 years, and about 20 people die waiting on the transplant list every day. o This crisis has necessitated the development of new strategies to acquire organs for transplantation. Among these advances is the prospect of growing a custom organ for a recipient using chimeras. Chimeras are organisms made up of two genetically distinct types of cells. Chimerization can occur within a single species or between two different species. · The latter type has garnered interest among scientists as a possible method for generating organs suitable for human transplantation. The proposed strategy is to create a chimera from a non-human animal embryo, usually a: · pig, and · human stem cells. Eventually, after the chimera reaches adulthood, the stem cell donor will receive a transplant with a new, humanoid organ from the chimera. Naturally, crossing species and sacrificing animal lives for organ farming comes with some ethical baggage, but chimera research has been prominent for several decades and foretells a bright future. An effort has been made in this E-Booklet to inculcate medicos in the subject of Chimera Research, particularly how it pertains to organ transplantation, and spark healthy debate surrounding the ethics of this medical advance. …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London).
Download or read book Chimeras Hybrids and Interspecies Research written by Andrea L. Bonnicksen and published by Georgetown University Press. This book was released on 2009-09-21 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: In his 2006 State of the Union speech, President George W. Bush asked the U.S. Congress to prohibit the "most egregious abuses of medical research," such as the "creation of animal–human hybrids." The president's message echoed that of a 2004 report by the President's Council on Bioethics, which recommended that hybrid human–animal embryos be banned by Congress. Discussions of early interspecies research, in which cells or DNA are interchanged between humans and nonhumans at early stages of development, can often devolve into sweeping statements, colorful imagery, and confusing policy. Although today's policy advisory groups are becoming more informed, debate is still limited by the interchangeable use of terms such as chimeras and hybrids, a tendency to treat all forms of interspecies alike, the failure to distinguish between laboratory research and procreation, and not enough serious policy justification. Andrea Bonnicksen seeks to understand reasons behind support of and disdain for interspecies research in such areas as chimerism, hybridization, interspecies nuclear transfer, cross-species embryo transfer, and transgenics. She highlights two claims critics make against early interspecies studies: that the research will violate human dignity and that it can lead to procreation. Are these claims sufficient to justify restrictive policy? Bonnicksen carefully illustrates the challenges of making policy for sensitive and often sensationalized research—research that touches deep-seated values and that probes the boundary between human and nonhuman animals.
Download or read book The Chimera Principle written by Carlo Severi and published by Hau. This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using philosophical and ethnographic theory, presents new approaches to ritual and memory, relating them to visual and sound images as acts of communication.
Download or read book Chimerism written by Nicole L. Draper and published by Springer. This book was released on 2018-06-21 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a comprehensive, up-to-date review of chimerism. The first part of the volume presents the causes of chimerism, specifically focusing on fertilization and early embryonic errors, pregnancy and multiple gestations, and transplantation and transfusion. The second part of the volume outlines clinical identification and consequences of chimerism. Chapters in this section focus on the effects of chimerism on testing in relationship determination and forensics, prenatal genetic testing and screening, and blood and HLA typing. This part also reviews new data concerning matching donors and recipients for transplantation, while outlining the risks of transplantation, such as graft-vs-host disease and passenger lymphocyte syndrome. Additionally, evidence on the role of chimerism in autoimmune disease and cancer is presented. Written by experts in the field, Chimerism: A Clinical Guide is a valuable resource for clinicians and researchers that will help guide patient management and stimulate investigative efforts.
Download or read book Chimera Patterns in Networks written by Anna Zakharova and published by Springer Nature. This book was released on 2020-03-09 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book devoted to chimera states - peculiar partial synchronization patterns in networks. Providing an overview of the state of the art in research on this topic, it explores how these hybrid states, which are composed of spatially separated domains of synchronized and desynchronized behavior, arise surprisingly in networks of identical units and symmetric coupling topologies. The book not only describes various types of chimeras, but also discusses the role of time delay, stochasticity, and network topology for these synchronization-desynchronization patterns. Moreover, it addresses the question of robustness and control of chimera states, which have various applications in physics, biology, chemistry, and engineering. This book is intended for researchers with a background in physics, applied mathematics, or engineering. Of great interest to specialists working on related problems, it is also a valuable resource for newcomers to the field and other scientists working on the control of spatio-temporal patterns.
Download or read book Chimera s Children written by David Albert Jones and published by A&C Black. This book was released on 2012-11-02 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of the current context and ethical implications of human-nonhuman genetic combinations. The idea of human-nonhuman combinations has been a recurrent theme throughout the history of humanity. From the myths of the Minotaur and the centaurs in ancient Greece to the dogheads of the Middle Ages right through to the monsters of modern science fiction, these beings have always been a source of fascination. In recent years, however, biomedical advances have demonstrated the potential to make these entities a reality through the creation of inter-species combinations. As a result, pressing and perplexing ethical questions arise. Introducing the reader to the historical context of human-nonhuman experimentation and potential future developments, this volume offers clarification, analysis and a thorough overview of the ethical challenges relating to human-nonhuman chimeras, true hybrids, cybrids and other combinations. This book is the first accessible survey of the different ethical dilemmas facing contemporary society in the creation of human-nonhuman embryonic, foetal and postnatal entities. These include important cultural, legal, philosophical and religious perspectives. As such it will act as a springboard for future debate.
Download or read book CHIMBRIDS Chimeras and Hybrids in Comparative European and International Research written by Jochen Taupitz and published by Springer. This book was released on 2010-11-16 with total page 1039 pages. Available in PDF, EPUB and Kindle. Book excerpt: National, European and international concepts and strategies concerning the legal and ethical framework of chimera and hybrid research are still largely missing, even though they are absolutely necessary in order to use the potential of chimera and hybrid research effectively and efficiently for the benefit of science and society. The outcome of the CHIMBRIDS-Project successfully sheds light on the chances and risks of this research and provides legal solutions to existing problems in order to help decision-makers fulfil their tasks in an informed and efficient manner. This comprehensive volume details the complete results, contributed by 40 scholars from 10 member states of the European Union, Canada, China, Israel, Japan, Switzerland and the US, with descriptive reports of the legal situation in specific countries and in-depth analysis of all scientific, medical, ethical and legal implications of chimera and hybrid research.
Download or read book The Emerging Field of Human Neural Organoids Transplants and Chimeras written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2022-01-08 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: The United States military is arguably the most intensely technological, complex enterprise in existence. When compared to the gross domestic products of other countries, the Department of Defense (DoD) budget ranks above all but about 20 nations. If viewed as a company, it would be the largest globally with the most employees. Major investments in weapons systems using advanced technologies provide an advantage over competing systems. Each weapon, platform, vehicle, and person in an operating force is a node in one or more advanced networks that provide the ability to rapidly form a coherent force from a large number of broadly distributed elements. DoD's ability to create and operate forces of this nature demands a competent understanding by its workforce of the composition, acquisition, and employment of its technology-enabled forces. Review of Specialized Degree-Granting Graduate Programs of the Department of Defense in STEM and Management focuses on the graduate science, technology, engineering, mathematics and management (STEM+M) education issues of the Air Force, Navy, and Marines. This report assesses the cost, benefits, and organizational placement of DoD institutions that grant degrees in STEM+M and evaluates alternative ways - for example, civilian institutions and distance learning - to ensure adequate numbers and high-quality education outcomes for DoD personnel."--Publisher's description.
Download or read book Chimeras and Consciousness written by Lynn Margulis and published by MIT Press. This book was released on 2011 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists elucidate the astounding collective sensory capacity of Earth and its evolution through time.
Download or read book Plant Chimeras written by Richard A. E. Tilney-Bassett and published by Cambridge University Press. This book was released on 1991-10-03 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, which was originally published in 1986, introduces the reader to the main steps in the analysis of chimeras, explains their structural and developmental basis, and the ways of classifying and manipulating them. The twelve chapters separate types of chimeras according to their origin - by grafting or polyploidy; their structure - sectorial or periclinal; or according to the varied parts of the plant most affected - tubers, leaves, flowers or fruit. Throughout the book care is taken to distinguish between the activity of the growing-point in determining chimera structure, and the role of gene expression in determining appearance. Examples of the experimental uses of chimeras are given and of the valuable role they can play in studying fundamental questions of anatomical development; the disadvantages of chimeras in mutation breeding are discussed too.
Download or read book The Theory of the Free martin written by Frank Rattray Lillie and published by . This book was released on 1916 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Great Kanto Earthquake and the Chimera of National Reconstruction in Japan written by J. Charles Schenking and published by Columbia University Press. This book was released on 2013-07-09 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: In September 1923, a magnitude 7.9 earthquake devastated eastern Japan, killing more than 120,000 people and leaving two million homeless. Using a rich array of source material, J. Charles Schencking tells for the first time the graphic tale of Tokyo's destruction and rebirth. In emotive prose, he documents how the citizens of Tokyo experienced this unprecedented calamity and explores the ways in which it rattled people's deep-seated anxieties about modernity. While explaining how and why the disaster compelled people to reflect on Japanese society, he also examines how reconstruction encouraged the capital's inhabitants to entertain new types of urbanism as they rebuilt their world. Some residents hoped that a grandiose metropolis, reflecting new values, would rise from the ashes of disaster-ravaged Tokyo. Many, however, desired a quick return of the city they once called home. Opportunistic elites advocated innovative state infrastructure to better manage the daily lives of Tokyo residents. Others focused on rejuvenating society--morally, economically, and spiritually--to combat the perceived degeneration of Japan. Schencking explores the inspiration behind these dreams and the extent to which they were realized. He investigates why Japanese citizens from all walks of life responded to overtures for renewal with varying degrees of acceptance, ambivalence, and resistance. His research not only sheds light on Japan's experience with and interpretation of the earthquake but challenges widespread assumptions that disasters unite stricken societies, creating a "blank slate" for radical transformation. National reconstruction in the wake of the Great Kanto Earthquake, Schencking demonstrates, proved to be illusive.
Download or read book Science of Coercion written by Christopher Simpson and published by Open Road Media. This book was released on 2015-03-03 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: A provocative and eye-opening study of the essential role the US military and the Central Intelligence Agency played in the advancement of communication studies during the Cold War era, now with a new introduction by Robert W. McChesney and a new preface by the author Since the mid-twentieth century, the great advances in our knowledge about the most effective methods of mass communication and persuasion have been visible in a wide range of professional fields, including journalism, marketing, public relations, interrogation, and public opinion studies. However, the birth of the modern science of mass communication had surprising and somewhat troubling midwives: the military and covert intelligence arms of the US government. In this fascinating study, author Christopher Simpson uses long-classified documents from the Pentagon, the CIA, and other national security agencies to demonstrate how this seemingly benign social science grew directly out of secret government-funded research into psychological warfare. It reveals that many of the most respected pioneers in the field of communication science were knowingly complicit in America’s Cold War efforts, regardless of their personal politics or individual moralities, and that their findings on mass communication were eventually employed for the purposes of propaganda, subversion, intimidation, and counterinsurgency. An important, thought-provoking work, Science of Coercion shines a blazing light into a hitherto remote and shadowy corner of Cold War history.
Download or read book Chimeras of Form written by Aarthi Vadde and published by Columbia University Press. This book was released on 2016-12-13 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the years following World War I, the “international” emerged as a distinct scale of political and cultural focus. Internationalisms proliferated in kind as writers and thinkers sought to imagine modes of cooperation that would balance transnational solidarities with national sovereignty. While so-called political realists across the twentieth century have regarded such attempts as wishful thinking, Aarthi Vadde argues that the negotiation of wishing and thinking is at the very heart of internationalism. In Chimeras of Form, she shows why modernist literary form is essential to understanding the aspirational and analytical force of internationalism in and beyond Europe. Major writers such as Rabindranath Tagore, James Joyce, Claude McKay, George Lamming, Michael Ondaatje, and Zadie Smith use modernist strategies to reshape how readers think about the cohesion and interrelation of political communities in the wake of empire. Vadde lucidly explains how their formal experiments with the novel, short story, poetry, and political essay contribute to and sometimes even anticipate debates in postcolonial theory and cosmopolitanism. She reads Joyce’s use of asymmetrical narratives as a way to ask questions about international camaraderie, and demonstrates how the “plotless” works of McKay and Lamming upturn ideas of citizenship and diasporic alienation. Her analysis of twenty-first-century writers Smith and Shailja Patel shows how ongoing conflicts around migration, displacement, and global economic inequality link modernist, postcolonial, and contemporary traditions of literature. Vadde brings these traditions together to reveal the dual nature of internationalism as an ambition, possibly a chimeric one, and an actual political discourse vital to understanding our present moment.
