Download or read book Chemotherapy of Bacterial Infections written by R. J. Schnitzer and published by Elsevier. This book was released on 2013-09-12 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental Chemotherapy, Volume II: Chemotherapy of Bacterial Infections: Part I is devoted to the history, development, and progress of experimental chemotherapy of bacterial infections. The subject matter has been arranged according to particular groups of compounds, and in a few instances according to specific diseases. The emphasis of Volume II is placed on synthetic compounds. The literature is covered up to the latter part of 1963. It is hoped that this volume will be found useful by investigators and teachers concerned with experimental work on new substances and by physicians and veterinarians who use them. The book opens with a discussion of chemotherapy with antibacterial dyestuffs. This is followed by separate chapters on the mode of action of antibacterial substances such as sulfonamides, penicillins, and other antibiotics; the main lines on which research into antibacterial drugs has developed; and drug resistance for chemotherapy. Subsequent chapters deal with antibacterial chemotherapy with sulfonamides, the experimental pharmacology and toxicology of sulfonamides, the use of nitrofurans as chemotherapeutic agents, and antibacterial agents of limited action. The final chapters discuss experimental chemotherapy of tuberculosis and leprosy.
Download or read book Antimicrobial Chemotherapy written by Roger Finch and published by OUP Oxford. This book was released on 2012-01-05 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents. Public awareness and concerns about drug resistant organisms has led to widespread publicity and political action in the UK, Europe and worldwide. The control of drug resistance and the implementation of good prescribing practice are now legal requirements in the UK as a result of the UK Health Act (2008). These fundamental changes underscore the need for a thorough understanding of the advantages and risks associated with specific antibiotic choices. This sixth edition of Antimicrobial Chemotherapy continues to be a valuable resource for undergraduates and graduates requiring a thorough grounding in the scientific basis and clinical application of these drugs. This new edition is updated to include the most recently licensed agents, notably in the treatment of viral infections including HIV/AIDS, and contains new guidance on prescribing practice and infection control practices that limit the development and spread of resistant organisms.
Download or read book Chemotherapy written by J. D. Williams and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Society of Chemotherapy meets every two years to review progress in chemotherapy of infections and of malignant disease. Each meeting gets larger to encompass the extension of chemotherapy into new areas. In some instances, expansion has been rapid, for example in cephalosporins, pen icillins and combination chemotherapy of cancer - in others slow, as in the field of parasitology. New problems of resistance and untoward effects arise; reduction of host toxicity without loss of antitumour activity by new substances occupies wide attention. The improved results with cancer chemotherapy, es pecially in leukaemias, are leading to a greater prevalence of severe infection in patients so treated, pharmacokinetics of drugs in normal and diseased subjects is receiving increasing attention along with related problems of bioavailability and interactions between drugs. Meanwhile the attack on some of the major bacterial infections, such as gonorrhoea and tubercu losis, which were among the first infections to feel the impact of chemotherapy, still continue to be major world problems and are now under attack with new agents and new methods. From this wide field and the 1,000 papers read at the Congress we have produced Proceedings which reflect the variety and vigour of research in this important field of medicine. It was not possible to include all of the papers presented at the Congress but we have attempted to include most aspects of cur rent progress in chemotherapy.
Download or read book Antimicrobial Chemotherapy written by Peter Davey and published by Oxford University Press, USA. This book was released on 2015 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preceded by: Antimicrobial chemotherapy / Roger Finch ... [et al.]. 6th ed. 2012.
Download or read book Infections in Cancer Chemotherapy written by J. Klastersky and published by Elsevier. This book was released on 2013-10-22 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infections in Cancer Chemotherapy is a collection of paper that details the advancement in the understanding of infections in chemotherapy. The coverage of the text includes aggressive cancer treatment and its role in predisposing to infection; diagnosis of infection in patients with cancer; and non-bacterial infections associated with neoplastic disease. The selection also tackles the protocol for an international prospective trial of initial therapy regimens in neutropenic patients with malignant disease; and the use of gnotobiotics in hematology in improving acute leukemia treatment. The book will be of great interest to oncologists and hematologists.
Download or read book Antibacterial Chemotherapy written by Sebastian Amyes and published by OUP Oxford. This book was released on 2010-02-25 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although antibiotics are among the most widely used pharmaceuticals, they are also often inappropriately and over-prescribed. Indeed there are increasing predictions that unless we moderate our use of these drugs, bacterial resistance will eventually render them useless. As there are no serious contenders to take the place of antibiotics, including a failure to find new classes of these drugs, it is essential for modern medicine that their efficacy is preserved. Part of the Oxford Infectious Disease Library, this pocketbook is designed to help medical trainees, general prescribers, healthcare workers and students of all biological and medical sciences to understand how antibiotics work, to demonstrate where they might be most appropriate and to make clear the threat of antibiotic resistance. In particular, it will highlight the problems currently seen with bacteria such as MRSA and describe the circumstances leading to their persistence.
Download or read book Special Problems in Chemotherapy written by J. D. Williams and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Society of Chemotherapy meets every two years to review progress in chemotherapy of infections and of malignant disease. Each meeting gets larger to encompass the extension of chemotherapy into new areas. In some instances, expansion has been rapid, for example in cephalosporins, pen icillins and combination chemotherapy of cancer - in others slow, as in the field of parasitology. New problems of resistance and untoward effects arise; reduction of host toxicity without loss of antitumour activity by new substances occupies wide attention. The improved results with cancer chemotherapy, es pecially in leukaemias, are leading to a greater prevalence of severe infection in patients so treated, pharmacokinetics of drugs in normal and diseased subjects is receiving increasing attention along with related problems of bioavailability and interactions between drugs. Meanwhile the attack on some of the major bacterial infections, such as gonorrhoea and tubercu losis, which were among the first infections to feel the impact of chemotherapy, still continue to be major world problems and are now under attack with new agents and new methods. From this wide field and the 1,000 papers read at the Congress we have produced Proceedings which reflect the variety and vigour of research in this important field of medicine. It was not possible to include all of the papers presented at the Congress but we have attempted to include most aspects of cur rent progress in chemotherapy.
Download or read book Antibiotic and Chemotherapy E Book written by Roger G. Finch and published by Elsevier Health Sciences. This book was released on 2010-11-30 with total page 913 pages. Available in PDF, EPUB and Kindle. Book excerpt: Well-respected and widely regarded as the most comprehensive text in the field, Antibiotic and Chemotherapy, 9th Edition by Drs. Finch, Greenwood, Whitley, and Norrby, provides globally relevant coverage of all types of antimicrobial agents used in human medicine, including all antiviral, antiprotozoan and anthelminthic agents. Comprehensively updated to include new FDA and EMEA regulations, this edition keeps you current with brand-new information about antiretroviral agents and HIV, superficial and mucocutaneous myscoses and systemic infections, management of the immunocompromised patient, treatment of antimicrobial resistance, plus coverage of new anti-sepsis agents and host/microbe modulators. Reference is easy thanks to a unique 3-part structure covering general aspects of treatment; reviews of every agent; and details of treatments of particular infections. Offer the best possible care and information to your patients about the increasing problem of multi-drug resistance and the wide range of new antiviral therapies now available for the treatment of HIV and other viral infections. Stay current with 21 new chapters including the latest information on superficial and mucocutaneous mycoses, systemic infections, anti-retroviral agents, and HIV. Get fresh perspectives and insights thanks to 21 newly-authored and extensively re-written chapters. Easily access information thanks to a unique 3-part structure covering general aspects of treatment; reviews of every agent; and details of treatments of particular infections. Apply the latest treatments for anti-microbial organisms such as MRSA, and multi-drug resistant forms of TB, malaria and gonorrhea. Keep up on the latest FDA and EMEA regulations.
Download or read book Guide to Chemotherapy and Chemoprophylaxis in Bacterial Infections written by Y. Z. Abou and published by . This book was released on 1998 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to the rational and safe prescribing of antimicrobials in the treatment and prevention of bacterial infections. Now in its second revised edition. the book gives particular attention to the management of infections commonly found in Eastern Mediterranean countries. Addressed to physicians, the guide responds to the urgent need to prevent the misuse of antibiotics, protect against the emergence of resistant bacterial strains and reduce the waste of resources spent on useless treatments. The manual has five chapters. The first explains the general principles of safe and effective antimicrobial therapy, emphasizing the many factors that need to be considered when selecting drugs, doses and modes of administration. The second chapter, which constitutes the core of the manual, provides precise prescribing guidelines for the management of 77 bacterial infections. For each infection, information includes relevant diagnostic advice, the most likely causative organisms listed in the order of frequency, the first-choice drug or combination, followed by alternatives and advice on dosage, mode of administration and duration of therapy. The third chapter outlines essential information about the properties, advantages and limitations of topical preparations for use as disinfectants, antiseptics, cleaning agents and antibiotics. Chemoprophylaxis is covered in the fourth chapter, which describes indications for chemoprophylaxis to prevent wound infection and sepsis in surgery, to prevent selected infections and to prevent bacterial endocarditis. The concluding chapter sets out dosage ranges for 27 commonly used antimicrobials.
Download or read book Experimental Chemotherapy Chemotherapy of bacterial infections pt 1 written by Robert J. Schnitzer and published by . This book was released on 1964 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemotherapy of Viral Infections written by P E. Came and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: " . . . the motto for the therapeutics of the future will have to be de sedibus et causis pharmacorum. " P. EHRLICH, 1909 Exciting events in the basic disciplines of virology, immunology, and pharmacology continue to advance the understanding of the pathogenesis and control of virus diseases. At the same time, the rational development of antiviral agents is attracting, to an increasing extent, the interest of workers in other disciplines. Improvements in technology facilitate the definition of potential target sites for antiviral intervention and unmask new viral and host genes. The outcome is a further steady development of new antiviral agents which approach the "magic bullets" first proposed by PAUL EHRLICH. Remarkable advances in protein synthetic methods that yield polypeptides which inhibit active sites of viral proteins have aided substantially in the basic and clinical study of these antiviral agents. In addition, the extremely rapid progression in recombinant DNA techniques, leading to the synthesis of large quantities of gene products, is also increasing our opportunities at a dashing pace. New information and developing technology facilitate research on the mechanism of action, toxicity, pharmacokinetics, and pharmacodynamics of new agents. The list of clinically effective antiviral agents is expanding and the number of potentially useful compounds is growing rapidly. This book is a combined theoretical text and practical manual which, it is hoped, will be of use to all who have an interest in virus diseases, particularly scientists, physicians and graduate students.
Download or read book Experimental Chemotherapy written by and published by . This book was released on 1964 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Laboratory Aspects of Infections written by J. D. Williams and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Society of Chemotherapy meets every two years to review progress in chemotherapy of infections and of malignant disease. Each meeting gets larger to encompass the extension of chemotherapy into new areas. In some instances, expansion has been rapid, for example in cephalosporins, pen icillins and combination chemotherapy of cancer - in others slow, as in the field of parasitology. New problems of resistance and untoward effects arise; reduction of host toxicity without loss of antitumour activity by new substances occupies wide attention. The improved results with cancer chemotherapy, es pecially in leukaemias, are leading to a greater prevalence of severe infection in patients so treated, pharmacokinetics of drugs in normal and diseased subjects is receiving increasing attention along with related problems of bioavailability and interactions between drugs. Meanwhile the attack on some of the major bacterial infections, such as gonorrhoea and tubercu losis, which were among the first infections to feel the impact of chemotherapy, still continue to be major world problems and are now under attack with new agents and new methods. From this wide field and the 1,000 papers read at the Congress we have produced Proceedings which reflect the variety and vigour of research in this important field of medicine. It was not possible to include all of the papers presented at the Congress but we have attempted to include most aspects of cur rent progress in chemotherapy.
Download or read book Antibacterial Chemotherapeutic Agents written by S.L. Dax and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past 50 years a wide variety of antibacterial substances have been discovered and synthesised, and their use in treating bacterial infection has been spectacularly successful. Today there are several general classes of antibacterial drugs, each having a well established set of uses, and together they form the mainstay of modern antibacterial chemotherapy. In search for new and improved agents, the pharmaceutical researcher needs to be well informed on many topics, including existing agents, their modes of action and pharmacology, and possible synthetic approaches. In this new book the author has brought together a wide range of information on the principal classes of antibacterial agents, and he covers, for each group, their history, mode of action, key structural features, synthesis and bacterial resistance. The result is a compact and concise overview of these very important classes of antibacterial agents.
Download or read book Treating Infectious Diseases in a Microbial World written by National Research Council and published by National Academies Press. This book was released on 2006-01-03 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.
Download or read book Handbook of Animal Models of Infection written by Merle A. Sande and published by Academic Press. This book was released on 1999-05-28 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Animal Models of Infection is a complete revision of a three-volume text that was published in 1986. It incorporates the major advances in the field during the past decade, in particular those concerning molecular biological procedures and new models that have been developed. It focuses on both methods and techniques, which makes it an essential and comprehensive reference as well as a benchtop manual. The Handbook will help investigators save time and effort in formulating an approach to test a new potential therapeutic agent or combination of agents for in vivo efficacy and to position the therapy for specific infections where it may have therapeutic promise. The book is divided into five sections; the first covering the general methodologies, followed by sections describing experimental bacterial, mycotic, parasitic, and viral infections. Discusses ethical and safety aspects in an introductory background section Covers principles of animal care and current techniques appropriate for the use of animal models of infection Details a wide range of animals including rodents, rabbits, cats, and primates Provides hands-on descriptions of how to set up the model Discusses the major advantages and limitations of each model Ensures full coverage of bacterial, fungal, viral, and parasitic infections
Download or read book Antibiotics and Chemotherapy written by R.N. Grüneberg and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to provide reviews of various antibiotic topics which will be of interest to practising clinicians and to microbiologists. It is hoped that enough references have been provided to enable the enthusiast to immerse himself in the source literature. No attempt has been made to cover the whole field, which is well catered for in the numerous works on the subject. Rather, the intention has been to select a number of topics in which there has been a great deal of change in recent years, and to ask an appropriate authority to review the subject. Since I chose the topics, it may be supposed, quite correctly, that I have identified subjects in which I felt myself to require some postgraduate education. The process was something like the well known radio programme in which a castaway is allowed to select a number of gramophone records to take with him to a desert island. I hope that readers will share my interest in the contributions from a number of distinguished contributors to the field of antibiotic chemotherapeutic research. Although I have had the privilege of editing this volume it will be understood that the views expressed by the authors are their own and have not been the subject of editorial review. I am grateful to all the collaborators in this volume, and to the publishers, MTP Press, for their help, and for asking me to undertake the task. R. N.
