Download or read book Chemical Diversity of Plant Specialized Metabolites written by Bratati De and published by Royal Society of Chemistry. This book was released on 2023-07-19 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The phytochemical constituents of plants fall into two main categories based on their role in basic metabolic processes: primary and secondary. Primary metabolites are involved in basic life functions and are similar in all living cells, whereas secondary metabolites are derived from subsidiary pathways. Although traditionally referred to as secondary metabolites, more recently these compounds have been termed ‘plant specialized metabolites’, as the exact biochemical boundary between primary and secondary metabolites has not been fully established. Plant specialized metabolites are the main elements in the study and use of ‘medicinal’ plants and herbs, as well as in nutrition and food chemistry. In modern medicine, plant specialized metabolites provide many of the lead compounds in the production of medicines targeted at treating a broad variety of diseases. Such metabolites also play an important role in sessile plants to resist and withstand different biotic and abiotic stresses. Plant specialized metabolites are classified according to their chemical structures and this book will present the different classes in turn, while discussing their sources and distribution in plant families, their biosynthetic pathways, and their important and notable uses in phytochemistry and pharmacology. Chemical Diversity of Plant Specialized Metabolites will be a useful guide and reference point for chemists and students in many disciplines including synthetic organic chemists, medicinal chemists, plant scientists, pharmacognosists, chemical ecologists, bioengineers, and synthetic biologists, in addition to those working in related fields.
Download or read book Profiling Structure Elucidation and Interrogation of Biosynthesis of Specialized Metabolites of the Solanaceae Using Liquid Chromatography Mass Spectrometry and Stable Isotope Labeling written by Xiaoxiao Liu and published by . This book was released on 2017 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Plant Specialized Metabolism written by Gen-ichiro Arimura and published by CRC Press. This book was released on 2016-10-26 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in science have clarified the role of plant specialized metabolites (classically known as plant secondary metabolites), which cannot be considered only bioactive molecules used for human health but also pivotal factors for the global ecosystem. They play major roles in plant life, evolution, and mutualism. To provide the reader a general view of plant specialized metabolites, it is important to consider both the biochemistry and the functional/ecological role of these important compounds. Around 200,000 specialized metabolites are formed by a wide array of plant metabolic pathways from numerous plant taxa and through learning how other species (including human beings) rely on them. Plant Specialized Metabolism: Genomics, Biochemistry, and Biological Functions will provide the reader with special insights into the sophisticated nature of these metabolites and their various and valuable uses based on the most recent findings in science. The field of plant specialized metabolism has witnessed tremendous growth in the past decade. This growth has had a profound impact on multiple disciplines in life science, including biochemistry, metabolism, enzymology, natural product chemistry, medicinal chemistry, chemical ecology, and evolution. It also has yielded valuable knowledge and technology readily applicable in various industries, such as agriculture, horticulture, energy, renewable chemicals, and pharmaceuticals. The book focuses on the molecular background of secondary metabolite biosynthesis, their functional role, and potential applications.
Download or read book Specialized Plant Metabolites as Cosmeceuticals written by Deepika Kathuria and published by Elsevier. This book was released on 2024-08-15 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specialized Plant Metabolites as Cosmeceuticals presents a comprehensive guide to traditional medicinal plants that are used in the field of cosmetics. Chapters cover geographical distribution, extraction of key components from each plant, traditional uses, pharmacognostic characteristics, phytochemistry, pharmacology, toxicology and future prospects. This book will be a valuable asset for researchers and graduate students of chemistry, botany, biotechnology, microbiology, cosmetology and the pharmaceutical sciences. As medicinal plants are a rich source of a variety of bioactive secondary metabolites, their wide range of pharmacological applications as antibiotics, antifungals, anticancer agents, and antimicrobial and antiviral applications provide new and exciting avenues. In addition, they have great implications for the food, pharmaceutical, cosmetics and personal care product industries. Secondary metabolites also ecofriendly, cost effective, biocompatible and cause less side effects as compare to synthetic compounds. Highlights comprehensive information on major classes of plant secondary metabolites with potent cosmeceutical applications Provides details on the encapsulation of secondary metabolites for the betterment of cosmeceutical products Covers toxicity of secondary metabolite based cosmeceuticals
Download or read book Plant Metabolomics written by Kazuki Saito and published by Springer Science & Business Media. This book was released on 2006-06-29 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics – which deals with all metabolites of an organism – is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology. This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.
Download or read book Exploring and Engineering Plant Specialized Metabolism Latest Advances and New Horizons written by Thu Thuy Dang and published by Frontiers Media SA. This book was released on 2021-12-21 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biosynthesis written by Finian J. Leeper and published by Springer. This book was released on 2003-07-01 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the second of two volumes that deal with discovery of chemical pathways of biosynthesis of natural products (secondary metabolites). The first volume covered the use of isotopes in biosynthetic research and the formation of enzyme cofactors and reduced polyketides. This second volume describes biosynthesis of aromatic (unreduced) polyketides, enzymes responsible for cyclization of terpenoids (isoprenoids), and biochemical generation of selected classes of alkaloids (prenylated tryptophan, tropane, pyrrolizidine). Knowledge of the pathways and the techniques to elucidate them opens the door to combinatorial biosynthesis as well as to the production of targeted pharmaceutical agents utilizing a combination of chemistry, molecular biology and protein biochemistry.
Download or read book Chemicals from Plants written by Nicholas J. Walton and published by World Scientific. This book was released on 1999 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual is principally concerned with the small molecules produced by plants. It covers aspects of theirrole in plant ecology, their metabolism in the plant, their discovery, characterization and use and their significance in the diet.
Download or read book Biochemistry and Molecular Biology of Plants written by Bob B. Buchanan and published by John Wiley & Sons. This book was released on 2015-08-31 with total page 1280 pages. Available in PDF, EPUB and Kindle. Book excerpt: With over 1000 original drawings and 500 photographs, this work offers complete coverage of cell biology, plant physiology and molecular biology.
Download or read book Investigation of Plant Specialized Metabolism Secondary Metabolism Using Metabolomic and Proteomic Approaches written by Zhengzhi Xie and published by . This book was released on with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specialized metabolism (secondary metabolism) in glandular trichomes of sweet basil (Ocimum basilicum L.) and accumulation of specialized metabolites (secondary metabolites) in rhizomes of turmeric (Curcuma longa L.) was investigated using proteomic and metabolomic approaches, respectively. In an effort to further clarify the regulation of metabolism in the glandular trichomes of sweet basil, we utilized a proteomics-based approach that applied MudPIT (multidimensional protein identification technology) and GeLC-MS/MS (gel enhanced LC-MS/MS) to protein samples from isolated trichomes of four different basil lines: MC, SW, SD, and EMX-1. Phosphorylation, ubiquitination and methylation of proteins in these samples were detected using X!tandem. Significant differences in distribution of the 755 non-redundant protein entries demonstrated that the proteomes of the glandular trichomes of the four basil lines were quite distinct. Correspondence between proteomic, EST, and metabolic profiling data demonstrated that both transcriptional regulation and post-transcriptional regulation contribute to the chemical diversity. One very interesting finding was that precursors for different classes of terpenoids, including mono- and sesquiterpenoids, appear to be almost exclusively supplied by the MEP (2-C-methyl-D-erythritol 4-phosphate) pathway, but not the mevolonate pathway, in basil glandular trichomes. Our results suggest that carbon flow can be readily redirected between the phenylpropanoid and terpenoid pathways in this specific cell type. To investigate the impact of genetic, developmental and environmental factors on the accumulation of phytochemicals in rhizomes of turmeric, we performed metabolomic analysis in a 2(ʹʹ2(ʹʹ4 full factorial design experiment using GC-MS, LC-MS, and LC-PDA. Our results showed that growth stage had the largest effect on levels of the three major curcuminoids. Co-regulated metabolite modules were detected, which provided valuable information for identification of phytochemicals and investigation of their biosynthesis. Based on LC-MS/MS data, 4 new diarylheptanoids were tentatively identified in turmeric rhizomes using Tandem-MS-ASC, a home-made software tool that automatically recognizes spectra of unknown compounds using three approaches. Based on our metabolomic results, we proposed two new strategies, "metabolomics-guided discovery"and"correlation bioassay", to identify bioactive constituents from plant extracts based on information provided by metabolomic investigation.
Download or read book Fragment based Approaches in Drug Discovery written by Wolfgang Jahnke and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information that was previously unavailable. Adopting a practice-oriented approach, this represents a book by professionals for professionals, tailor-made for drug developers in the pharma and biotech sector who need to keep up-to-date on the latest technologies and strategies in pharmaceutical ligand design. The book is clearly divided into three sections on ligand design, spectroscopic techniques, and screening and drug discovery, backed by numerous case studies.
Download or read book Plant derived Natural Products written by Anne E. Osbourn and published by Springer Science & Business Media. This book was released on 2009-07-07 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.
Download or read book The Ecology of Plant Secondary Metabolites written by Glenn R. Iason and published by Cambridge University Press. This book was released on 2012-04-19 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a state-of-the-art review of recent conceptual developments concerning the roles of plant secondary metabolites in the natural environment.
Download or read book Plant Metabolites and Regulation under Environmental Stress written by Parvaiz Ahmad and published by Academic Press. This book was released on 2018-03-19 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant Metabolites and Regulation Under Environmental Stress presents the latest research on both primary and secondary metabolites. The book sheds light on the metabolic pathways of primary and secondary metabolites, the role of these metabolites in plants, and the environmental impact on the regulation of these metabolites. Users will find a comprehensive, practical reference that aids researchers in their understanding of the role of plant metabolites in stress tolerance. Highlights new advances in the understanding of plant metabolism Features 17 protocols and methods for analysis of important plant secondary metabolites Includes sections on environmental adaptations and plant metabolites, plant metabolites and breeding, plant microbiome and metabolites, and plant metabolism under non-stress conditions
Download or read book The Plant Vacuole written by and published by Elsevier. This book was released on 1997-05-06 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Botanical Research is a multi-volume publication that brings together reviews by recognized experts on subjects of importance to those involved in botanical research. For more than thirty years, Advances in Botanical Research has earned a reputation for excellence in the field. For those working on plant pathology, Advances in Plant Pathology has also carved a niche in the plant sciences during its decade of publication.Academic Press has merged Advances in Plant Pathology into Advances in Botanical Research. The plant science community will find that the merger of these two serials will provide one comprehensive resource for the field. To ensure complete coverage, John Andrews and Inez Tommerup, the editors of Advances in Plant Pathology, have joined the editorial board of the new series, which will include equal coverage of plant pathology and botany in both thematic and mixed volumes. The first few volumes of the new series will be slanted toward botany or plant pathology; however, future eclectic volumes will be fully integrated.The resulting synergy of these two serials greatly benefits the plant science community by providing a more comprehensive resource under one roof. The joint aim is to continue to include the very best articles, thereby maintaining the status of a high impact factor review series.
Download or read book Secondary Metabolites of Medicinal Plants written by Bharat Singh and published by John Wiley & Sons. This book was released on 2020-03-06 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers the structurally diverse secondary metabolites of medicinal plants, including their ethnopharmacological properties, biological activity, and production strategies Secondary metabolites of plants are a treasure trove of novel compounds with potential pharmaceutical applications. Consequently, the nature of these metabolites as well as strategies for the targeted expression and/or purification is of high interest. Regarding their biological and pharmacological activity and ethnopharmacological properties, this book offers a comprehensive treatment of 100 plant species, including Abutilon, Aloe, Cannabis, Capsicum, Jasminum, Malva, Phyllanthus, Stellaria, Thymus, Vitis, Zingiber, and more. It also discusses the cell culture conditions and various strategies used for enhancing the production of targeted metabolites in plant cell cultures. Secondary Metabolites of Medicinal Plants: Ethnopharmacological Properties, Biological Activity and Production Strategies is presented in four parts. Part I provides a complete introduction to the subject. Part II looks at the ethnomedicinal and pharmacological properties, chemical structures, and culture conditions of secondary metabolites. The third part examines the many strategies of secondary metabolites production, including: biotransformation; culture conditions; feeding of precursors; genetic transformation; immobilization; and oxygenation. The last section concludes with an overview of everything learned. -Provides information on cell culture conditions and targeted extraction of secondary metabolites confirmed by relevant literature -Presents the structures of secondary metabolites of 100 plant species together with their biological and pharmacological activity -Discusses plant species regarding their distribution, habitat, and ethnopharmacalogical properties -Presents strategies of secondary metabolites production, such as organ culture, pH, elicitation, hairy root cultures, light, and mutagenesis Secondary Metabolites of Medicinal Plants is an important book for students, professionals, and biotechnologists interested in the biological and pharmacological activity and ethnopharmacological properties of plants.
Download or read book Plant ABC Transporters written by Markus Geisler and published by Springer. This book was released on 2014-09-06 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to the fascinating superfamily of plant ATP-binding cassette (ABC) transporters and their variety of transported substrates. It highlights their exciting biological functions, covering aspects ranging from cellular detoxification, through development, to symbiosis and defense. Moreover, it also includes a number of chapters that center on ABC transporters from non-Arabidopsis species. ABC proteins are ubiquitous, membrane-intrinsic transporters that catalyze the primary (ATP-dependent) movement of their substrates through biological membranes. Initially identified as an essential aspect of a vacuolar detoxification process, genetic work in the last decade has revealed an unexpectedly diverse variety of ABC transporter substrates, which include not only xenobiotic conjugates, but also heavy metals, lipids, terpenoids, lignols, alkaloids and organic acids. The discovery that members of the ABCB and ABCG family are involved in the movement of phytohormones has further sparked their exploration and provided a new understanding of the whole family. Accordingly, the trafficking, regulation and structure-function of ABCB-type auxin transporters are especially emphasized in this book.
