Download or read book Charge Transfer Through a B type DNA Molecule written by Dale James Igram and published by . This book was released on 2014 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Charge Migration in DNA written by Tapash Chakraborty and published by Springer Science & Business Media. This book was released on 2007-08-15 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Charge migration through DNA has been the focus of considerable interest in recent years. This book presents contributions from an international team of researchers active in this field. It contains a wide range of topics that includes the mathematical background of the quantum processes involved, the role of charge transfer in DNA radiation damage, a new approach to DNA sequencing, DNA photonics, and many others.
Download or read book Charge Transport in DNA Insights from Simulations written by Wolter, Mario and published by KIT Scientific Publishing. This book was released on 2014-10-16 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Charge transport and charge transfer (CT) capabilities of deoxyribonucleic acid (DNA) are investigated. A QM/MM multi-scale framework is applied to calculate the CT capabilities of DNA under conditions resembling the experimental setup. The simulations are able to explain and predict the outcome of experiments and therefore make suggestions in advance. Based on the findings, suitable DNA sequences can be opted for the design of DNA-based devices as nano-scale electronic elements.
Download or read book Long Range Charge Transfer in DNA II written by Gary B. Schuster and published by Springer Science & Business Media. This book was released on 2004-04-08 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: with contributions by numerous experts
Download or read book Long Range Charge Transfer in DNA I written by Gary B. Schuster and published by Springer Science & Business Media. This book was released on 2004-03-24 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Theory of Electron Transfer and Molecular States in DNA written by Robert Günter Endres and published by . This book was released on 2002 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bionanoelectronics written by Daniela Dragoman and published by Springer Science & Business Media. This book was released on 2012-03-22 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the achievements in bionanoelectronics in a coherent manner. It deals with nanodevices applied to biostructures, molecular motors, molecular pumps, molecular nanoactuators and electronic biodevices, including nanodevices for sensing and imaging biomolcules. The book describes bionanoelectronics, detection of biomolecules and targets various biological applications such as detection and sequencing of DNA and early detection of various deseases and nanomedicine. Further important topics of the book are biomimetics and bioinspired electronics.The book also deals with biomolecules as building blocks of nanodevices for nanoelectronics or future computing architecture The application of scanning probe techniques to biological samples is described.
Download or read book Charge Transfer in DNA written by Hans-Achim Wagenknecht and published by John Wiley & Sons. This book was released on 2006-05-12 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past few years have witnessed intense research in this fascinating field as well as many controversial discussions. Now the time is ripe for a comprehensive book covering not only theoretical aspects, but also such mechanistic topics as principles and mechanisms of photoinduced charge injection, transport and trapping in DNA, sequence-dependent DNA dynamics, spectroscopic investigations of hole transport and much more. From the contents: * Principles and Mechanisms of Photoinduced Charge Injection, Transport and Trapping in DNA * Sequence-Dependent DNA Dynamics: The Regulator of DNA-Mediated Charge Transport * Excess Electron Transfer in DNA Probed with Flavin and Thymine Dimer Modified Oligonucleotides * Dynamics of Photoinitiated Hole and Electron Injection in Duplex DNA * Spectroscopic Investigation of Oxidative Hole Transfer via Adenine Hopping in DNA * Chemical Probing of Reductive Electron Transfer in DNA * Chemical Approach for Modulating Hole Transport in DNA * Spectroscopic Investigation of Charge Transfer in DNA * Spectroscopic Probing of Ultrafast Structural Relaxation and Electron Transfer Dynamics in DNA Edited by Hans-Achim Wagenknecht, and written by renowned international authors, this book provides an excellent overview with high quality contributions, making it a "must-have" for everyone working in the field.
Download or read book Probe Oxidative Damage in DNA Charge Transfer Process written by Huachuan Cao and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: As a hydrophilic biopolymer, a DNA molecule is surrounded by water molecules in aqueous solution. The charge hopping mechanism indicates the competition between radical cation quenching by water molecules and migration along DNA partially determines the distance and efficiency of charge transport in DNA. Lipid can effectively bind DNA to induce hydrophobic environment around the DNA helix and reduce the water contact with bases in the DNA duplex. Therefore, the effect of water molecules on charge transport can be studied by comparison between nature DNA and DNA-lipid complexes. We synthesized several cationic lipids with various lengths of dialkyl chain (2, 8, 18) and spermine (Sp4+) binding core in this research, which posses strong DNA binding affinity due to their multi-charged spermine head-groups. Among those, C8GlySp4+ and C2GlySp4+ can form stable complex with DNA oligomer in aqueous solution, characterized by time dependent UV and CD spectrometry. C2GlySp4+ showed the similar inhibition on oxidative damage in GG steps as spermine while C8GlySp4+ demonstrated much more significant prohibitive effect at the same concentration. Since all the lipids bear the same binding core, they should afford the similar binding affinity towards DNA duplexes. we attributed the observation to the longer length of dialkyl group in C8GlySp4+, which can more effectively shield the DNA duplex from the water molecules than either spermine or C2GlySp4+. A kinetic model based on phonon-assist polaron hopping mechanism was proposed to rationalize the experimental results. The finding may give insight on the protection of DNA oxidative damage by reducing the access of the water molecule to DNA duplex and may have potential impact on the application of DNA as conducting biopolymer and protection of DNA in biological system.
Download or read book Quantum Chemistry Simulation of Biological Molecules written by Eudenilson L. Albuquerque and published by Cambridge University Press. This book was released on 2021-02-11 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nano-biotechnology crosses the boundaries between physics, biochemistry and bioengineering, and has profound implications for the biomedical engineering industry. This book describes the quantum chemical simulation of a wide variety of molecular systems, with detailed analysis of their quantum chemical properties, individual molecular configurations, and cutting-edge biomedical applications. Topics covered include the basic properties of quantum chemistry and its conceptual foundations, the nanoelectronics and thermodynamics of DNA, the optoelectronic properties of the five DNA/RNA nucleobase anhydrous crystals, and key examples of molecular diode prototypes. A wide range of important applications are described, including protein binding of drugs such as cholesterol-lowering, anti-Parkinson and anti-migraine drugs, and recent developments in cancer biology are also discussed. This modern and comprehensive text is essential reading for graduate students and researchers in multidisciplinary areas of biological physics, chemical physics, chemical engineering, biochemistry and bioengineering.
Download or read book Molecular and Cellular Biophysics written by Jack A. Tuszynski and published by CRC Press. This book was released on 2018-10-24 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: From quantum theory to statistical mechanics, the methodologies of physics are often used to explain some of life's most complex biological problems. Exploring this challenging yet fascinating area of study, Molecular and Cellular Biophysics covers both molecular and cellular structures as well as the biophysical processes that occur in these structures. Designed for advanced undergraduate and beginning graduate students in biophysics courses, this textbook features a quantitative approach that avoids being too abstract in its presentation. Logically organized from small-scale (molecular) to large-scale (cellular) systems, the text first defines life, discussing the scientific controversies between mechanists and vitalists, the characteristics of living things, and the evolution of life. It then delves into molecular structures, including nucleic acids, DNA, RNA, interatomic interactions, and hydrogen bonds. After looking at these smaller systems, the author probes the larger cellular structures. He examines the cytoplasm, the cytoskeleton, chromosomes, mitochondria, motor proteins, and more. The book concludes with discussions on biophysical processes, including oxidative phosphorylation, diffusion, bioenergetics, conformational transitions in proteins, vesicle transport, subcellular structure formation, and cell division.
Download or read book Radiation Damage in Biomolecular Systems written by Gustavo García Gómez-Tejedor and published by Springer Science & Business Media. This book was released on 2012-01-04 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of X-rays and radioactivity, ionizing radiations have been widely applied in medicine both for diagnostic and therapeutic purposes. The risks associated with radiation exposure and handling led to the parallel development of the field of radiation protection. Pioneering experiments done by Sanche and co-workers in 2000 showed that low-energy secondary electrons, which are abundantly generated along radiation tracks, are primarily responsible for radiation damage through successive interactions with the molecular constituents of the medium. Apart from ionizing processes, which are usually related to radiation damage, below the ionization level low-energy electrons can induce molecular fragmentation via dissociative processes such as internal excitation and electron attachment. This prompted collaborative projects between different research groups from European countries together with other specialists from Canada, the USA and Australia. This book summarizes the advances achieved by these research groups after more than ten years of studies on radiation damage in biomolecular systems. An extensive Part I deals with recent experimental and theoretical findings on radiation induced damage at the molecular level. It includes many contributions on electron and positron collisions with biologically relevant molecules. X-ray and ion interactions are also covered. Part II addresses different approaches to radiation damage modelling. In Part III biomedical aspects of radiation effects are treated on different scales. After the physics-oriented focus of the previous parts, there is a gradual transition to biology and medicine with the increasing size of the object studied. Finally, Part IV is dedicated to current trends and novel techniques in radiation reserach and the applications hence arising. It includes new developments in radiotherapy and related cancer therapies, as well as technical optimizations of accelerators and totally new equipment designs, giving a glimpse of the near future of radiation-based medical treatments.
Download or read book Nanomachines written by Joseph Wang and published by John Wiley & Sons. This book was released on 2013-06-04 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomachines represent one of the most fascinating topics in of nanotechnology. These tiny devices provide diverse opportunities towards a wide range of important applications, ranging from targeted delivery of drug payloads to environmental remediation. This book addresses comprehensively the latest developments and discoveries in the field of nano- and microscale machines. It covers the evolution of nanomachines in general from a historical perspective, the fundamental challenges for motion at the nanoscale, different categories of biological and synthetic nano/microscale motors based on different propulsion mechanisms, ways for controlling the movement directionality and regulated speed, followed by detailed of major areas for which nanomachines has the potential to make a transformational impact. It ends with a futuristic look at nano/microscale machines and into their impact on the society. Key Features: * The only nanomachine introductory textbook currently available. * Written with college graduate level in mind to appeal to a broad interdisciplinary audience. * Covers the fundamental challenges for nanoscale motion. * Covers the latest advances in the design and operaton of a wide range of small-scale machines. * Covers diverse biomedical, environmental and technological applications of nanomachines. * Written in review format with cited articles to cover latest research and developments.
Download or read book Understanding DNA written by Chris R. Calladine and published by Academic Press. This book was released on 1997-03-14 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Second Edition of Understanding DNA has been entirely revised and updated, and expanded by more than 50% to cover new advances. The book explains step-by-step how DNA forms specific structures, the nature of these structures, and how they fundamentally affect the biological processes of transcription and replication.The functional properties of any molecule are directly related to and affected by its structure; this is especially true for DNA, the molecule that carries the code for all life on earth. Written in a clear, concise, and at times lively fashion, Understanding DNA is essential reading for all molecular biology, biochemistry, and genetics students, for newcomers to the field from such areas as physics or chemistry, and for even the most seasoned researchers who really want to understand DNA.Key Features* New edition, expanded by more than 50%* Completely revised and updated* Includes many additional and updated references* Summarizes the recent studies of DNA in disease and medicine* Contains more than 110 illustrations, some in full color* Describes the basic units of DNA and how these form the double helix* Characterizes the various types of DNA double helix that have been found* Explains how and why DNA twists and curves* Discusses the mechanisms of DNA supercoiling* Summarizes the assembly of DNA and proteins into chromosomes* Outlines the methods used to study DNA structureDescribes the latest work on protein-DNA complexes* Contains simple exercises and further reading at the end of each chapter
Download or read book Kinetics and Dynamics written by Piotr Paneth and published by Springer Science & Business Media. This book was released on 2010-08-03 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Kinetics and Dynamics" on molecular modeling of dynamic processes opens with an introductory overview before discussing approaches to reactivity of small systems in the gas phase. Then it examines studies of systems of increasing complexity up to the dynamics of DNA. This title has interdisciplinary character presenting wherever possible an interplay between the theory and the experiment. It provides basic information as well as the details of theory and examples of its application to experimentalists and theoreticians interested in modeling of dynamic processes in chemical and biochemical systems. All contributing authors are renowned experts in their fields and topics covered in this volume represent the forefront of today’s science.
Download or read book Long range Charge Transfer in DNA written by and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Chemical Biology of Nucleic Acids written by Naoki Sugimoto and published by Springer Nature. This book was released on 2023-07-29 with total page 2847 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is the first to comprehensively cover nucleic acids from fundamentals to recent advances and applications. It is divided into 10 sections where authors present not only basic knowledge but also recent research. Each section consists of extensive review chapters covering the chemistry, biology, and biophysics of nucleic acids as well as their applications in molecular medicine, biotechnology and nanotechnology. All sections within this book are: Physical Chemistry of Nucleic Acids (Section Editor: Prof. Roland Winter), Structural Chemistry of Nucleic Acids (Section Editor: Prof. Janez Plavec), Organic Chemistry of Nucleic Acids (Section Editor: Prof. Piet Herdewijin), Ligand Chemistry of Nucleic Acids (Section Editor: Prof. Marie-Paule Teulade-Fichou), Nucleic Acids and Gene Expression (Section Editor: Prof. Cynthia Burrows), Analytical Methods and Applications of Nucleic Acids (Section Editor: Prof. Chaoyong Yang), Nanotechnology and Nanomaterial Biology of Nucleic Acids (Section Editor: Prof. Zhen Xi), Nucleic Acids Therapeutics (Section Editor: Prof. Katherine Seley-Radtke), Biotechnology and Synthetic Biology of Nucleic Acids (Section Editor: Prof. Eriks Rozners), Functional Nucleic Acids (Section Editor: Prof. Keith R. Fox). The handbook is edited by outstanding leaders with contributions written by international renowned experts. It is a valuable resource not only for researchers but also graduate students working in areas related to nucleic acids who would like to learn more about their important role and potential applications.
