Download or read book Characterizing the Material Properties of Polymer based Microelectrode Arrays for Retinal Prosthesis written by Christina Soyeun Park and published by . This book was released on 2003 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Characterizing the Material Properties of Polymer Based Microelectrode Arrays for Retinal Prosthesis written by and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Retinal Prosthesis project is a three year project conducted in part at the Lawrence Livermore National Laboratory and funded by the Department of Energy to create an epiretinal microelectrode array for stimulating retinal cells. The implant must be flexible to conform to the retina, robust to sustain handling during fabrication and implantation, and biocompatible to withstand physiological conditions within the eye. Using poly(dimethyl siloxane) (PDMS), LLNL aims to use microfabrication techniques to increase the number of electrodes and integrate electronics. After the initial designs were fabricated and tested in acute implantation, it became obvious that there was a need to characterize and understand the mechanical and electrical properties of these new structures. This knowledge would be imperative in gaining credibility for polymer microfabrication and optimizing the designs. Thin composite microfabricated devices are challenging to characterize because they are difficult to handle, and exhibit non-linear, viscoelastic, and anisotropic properties. The objective of this research is to device experiments and protocols, develop an analytical model to represent the composite behavior, design and fabricate test structures, and conduct experimental testing to determine the mechanical and electrical properties of PDMS-metal composites. Previous uniaxial stretch tests show an average of 7% strain before failure on resistive heaters of similar dimensions deposited on PDMS. Lack of background information and questionable human accuracy demands a more sophisticated and thorough testing method. An Instron tensile testing machine was set up to interface with a digital multiplexor and computer interface to simultaneously record and graph position, load, and resistance across devices. With a compliant load cell for testing polymers and electrical interconnect grips designed and fabricated to interface the sample to the electronics, real-time resistance measurements were taken. Wafers of test structures were fabricated with variables such as lead width, pad to lead interface shape, PDMS thickness, metal (Ti and Au) thickness, and lead shape. Results showed that the serpentine shaped leads were 70% more effective, and that thicker adhesion layers of Ti were too brittle for testing. The other variables did not produce significant results.

Download or read book Microfabrication of an Implantable Silicone Microelectrode Array for an Epiretinal Prosthesis written by Mariam Nader Maghribi and published by . This book was released on 2003 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Microelectrode Arrays for Retinal Cell Stimulation written by Arti Patel and published by . This book was released on 2002 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Short Term Versus Long Term Challenges in Functional Biomaterials Interfacing Living Systems Two Sides of the Coin written by Davide Ricci and published by Frontiers Media SA. This book was released on 2022-03-11 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Thin Films and Coatings in Biology written by Soroush Nazarpour and published by Springer Science & Business Media. This book was released on 2013-08-15 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: The surface of materials is routinely exposed to various environmental influences. Surface modification presents a technological challenge for material scientists, physicists, and engineers, particularly when those surfaces are subjected to function within human body environment. This book provides a comprehensive coverage of the major issues and topics dealing with interaction of soft living matter with the surface of implants. Fundamental scientific concepts are embedded through experimental data and a broad range of case studies. First chapters cover the basics on biocompatibility of many different thin films of metals, alloys, ceramics, hydrogels, and polymers, following with case studies dealing with orthopedic and dental coatings. Next, a novel and low-cost coating deposition technique capable of production of several types of nanostructures is introduced through simple calculations and several illustrations. Moreover, chapter 6 and 7 present important topics on surface treatment of polymers, which is a subject that has seen many developments over the past decade. The last chapters target mainly the applications of coatings in biology such as in bio-sensing, neuroscience, and cancer detection. With several illustrations, micrographs, and case studies along with suitable references in each chapter, this book will be essential for graduate students and researchers in the multidisciplinary field of bio-coatings.

Download or read book Handbook of Humidity Measurement Volume 3 written by Ghenadii Korotcenkov and published by CRC Press. This book was released on 2020-01-24 with total page 959 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of unique water properties, humidity affects materials and many living organisms, including humans. Humidity control is important in various fields, from production management to creating a comfortable living environment. The range of materials that can be used in the development of humidity sensors is very broad, and the third volume of the Handbook of Humidity Measurement offers an analysis on various humidity-sensitive materials and sensor technologies used in the fabrication of humidity sensors and methods acceptable for their testing. Additional features include:  numerous strategies for the fabrication and characterization of humidity-sensitive materials and sensing structures used in sensor applications,  methods and properties to develop smaller, cheaper, more robust, and accurate devices with better sensitivity and stability,  a guide to sensor selection and an overview of the humidity sensor market, and  new technology solutions for integration, miniaturization, and specificity of the humidity sensor calibration. Handbook of Humidity Measurement, Volume 3: Sensing Materials and Technologies provides valuable information for practicing engineers, measurement experts, laboratory technicians, project managers in industries and national laboratories, and university students and professors interested in solutions to humidity measurement tasks. Despite the fact that this book is devoted to the humidity sensors, it can be used as a basis for understanding fundamentals of any gas sensor operation and development.

Download or read book Comprehensive Biomaterials II written by Kevin Healy and published by Elsevier. This book was released on 2017-05-18 with total page 4865 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications

Download or read book Nanomedicine Volume IIA written by Robert A. Freitas and published by CRC Press. This book was released on 2003-09-26 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The safety, effectiveness, and utility of medical nanorobotic devices will critically depend upon their biocompatibility with human organs, tissues, cells, and biochemical systems. In this Volume, we broaden the definition of nanomedical biocompatibility to include all of the mechanical, physiological, immunological, cytological, and biochemical re

Download or read book Implantable Neural Prostheses 2 written by David Zhou and published by Springer Science & Business Media. This book was released on 2010-07-10 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Signi?cant progress has been made in the development of neural prostheses for restoration of human functions and improvement of the quality of life. Biomedical engineers and neuroscientists around the world are working to improve the design and performance of existing devices and to develop novel devices for arti?cial vision, arti?cial limbs, and brain-machine interfaces. This book, Implantable Neural Prostheses 2: Techniques and Engineering Approaches, is part two of a two-volume sequence that describes state-of-the-art advances in techniques associated with implantable neural prosthetic devices. The techniques covered include biocompatibility and biostability, hermetic packaging, electrochemical techniques for neural stimulation applications, novel electrode materials and testing, thin-?lm ?exible microelectrode arrays, in situ char- terization of microelectrode arrays, chip-size thin-?lm device encapsulation, microchip-embedded capacitors and microelectronics for recording, stimulation, and wireless telemetry. The design process in the development of medical devices is also discussed. Advances in biomedical engineering, microfabrication technology, and neu- science have led to improved medical-device designs and novel functions. However, many challenges remain. This book focuses on the engineering approaches, R&D advances, and technical challenges of medical implants from an engineering p- spective. We are grateful to leading researchers from academic institutes, national laboratories, as well as design engineers and professionals from the medical device industry who have contributed to the book. Part one of this series covers designs of implantable neural prosthetic devices and their clinical applications.

Download or read book Neuromodulation written by Elliot Krames and published by Academic Press. This book was released on 2018-01-05 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuromodulation: Comprehensive Textbook of Principles, Technologies, and Therapies, Second Edition, serves as a comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. Since the publication of the first edition seven years ago, there has been an explosion of knowledge in neuromodulation, optogenetics, bioelectronics medicine and brain computer interfacing. Users will find unique discussions of the fundamental principles of neuromodulation and therapies, and how they are applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs. The book focuses on comprehensive coverage of spinal cord stimulation, non-interventional and interventional brain stimulation, peripheral nerve stimulation, and the emerging fields of neuromodulation, including optogenetics and bioelectronics medicine. Provides a comprehensive reference that covers all aspects of the growing field of neuromodulation Written by international, leading authorities in their respective fields of neuromodulation, pain management, functional neurosurgery and biomedical engineering Includes new chapters on optogenetics, bioelectronics medicine and brain computer interfacing

Download or read book Visual Prosthetics written by Gislin Dagnelie and published by Springer Science & Business Media. This book was released on 2011-02-19 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Visual Prosthetics provides an in-depth analysis of the principles of operation, current state, anticipated developments, and functional aspects of visual prosthetics restoring sight to visually impaired individuals. This volume uniquely describes the human visual system in health and disease in a pedagogical and didactic manner, fitting to professionals and researchers with a bioengineering background. Readers will find a balanced overview of electrical, molecular chemical and synthetic chromophore stimulation, in addition to the biophysics and psychological aspects of vision restoration. Unlike competitive texts, this introduction also includes the need and methods for functional evaluation and rehabilitation. Professionals in the field of biomedical engineering and graduate and postgraduate researchers will find Visual Prosthetics a valuable reference.

Download or read book Handbook of Neuroengineering written by Nitish V. Thakor and published by Springer Nature. This book was released on 2023-02-02 with total page 3686 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Handbook serves as an authoritative reference book in the field of Neuroengineering. Neuroengineering is a very exciting field that is rapidly getting established as core subject matter for research and education. The Neuroengineering field has also produced an impressive array of industry products and clinical applications. It also serves as a reference book for graduate students, research scholars and teachers. Selected sections or a compendium of chapters may be used as “reference book” for a one or two semester graduate course in Biomedical Engineering. Some academicians will construct a “textbook” out of selected sections or chapters. The Handbook is also meant as a state-of-the-art volume for researchers. Due to its comprehensive coverage, researchers in one field covered by a certain section of the Handbook would find other sections valuable sources of cross-reference for information and fertilization of interdisciplinary ideas. Industry researchers as well as clinicians using neurotechnologies will find the Handbook a single source for foundation and state-of-the-art applications in the field of Neuroengineering. Regulatory agencies, entrepreneurs, investors and legal experts can use the Handbook as a reference for their professional work as well.​

Download or read book Micro Electro Mechanical Systems written by Qing-An Huang and published by Springer. This book was released on 2018-05-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook volume aims to provide a comprehensive, self-contained, and authoritative reference in MEMS. It covers the theoretical and practical aspects including but not limited to sensors, actuators, RF MEMS, micro fluids and bio MEMS systems. It is particularly recommended to undergraduates, postgraduates, researchers, scientists, and field experts. This comprehensive summary will provide a solid knowledge background and inspire innovations in this highly interdisciplinary field. The handbook series consists of 5 volumes: Micro/nano fabrication technology, MEMS, Nanomaterial, Nanomedicine and Applications of micro-/nanotechnologies in IT. Experienced researchers and experts are invited to contribute in each of these areas.The series is published under Springer Major Reference works, which allows continuous online update and publication. These features allow newcomers and other readers to keep in touch with the most up-to-date information in micro-/nanotechnologies.It presents an overview of the knowledge base, as well as selected topics and provides comprehensive and authoritative information on the field for researchers, engineers, scientists and graduate students who are involved in different aspects of micro-/nanotechnologies.This publication will provide inspiration for innovative research and application ideas for continued growth of the field.

Download or read book Materials Science Engineering written by and published by . This book was released on 2004 with total page 1018 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nanomedicine written by Robert A. Freitas and published by . This book was released on 1999 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanosensors and nanorobots are not science fiction but part of nanomedicine, the newest direction in medicine. After touring medical history and defining molecular nanotechnology as the atomic-level control of molecular structures to create precisely targeted medical procedures, Freitas (Institute for Molecular Manufacturing, Palo Alto, CA) details such topics as molecular transport and device applications but leaves ethical debates to others. Appends data on nanodevice design, and human blood and cell types; and a 36-page glossary. Part of a three-volume work, due to be available online. Annotation copyrighted by Book News, Inc., Portland, OR.

Download or read book Research Awards Index written by and published by . This book was released on 1977 with total page 1378 pages. Available in PDF, EPUB and Kindle. Book excerpt: