Download or read book HTLV 1 Addressing Unmet Research Needs written by Louis M. Mansky and published by Frontiers Media SA. This book was released on 2021-05-20 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Human Cancer Viruses written by John Nicholas and published by Karger Medical and Scientific Publishers. This book was released on 2008-01-01 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first identification of a tumor-causing virus, Rous sarcoma virus, occurred almost 100 years ago, but it was not until the 1970s that the genetic basis for oncogenesis by this and other acutely transforming retroviruses was appreciated. Since then, numerous viral oncogenes and their corresponding cellular proto-oncogene counterparts have been identified, and these studies have contributed much to our understanding of crucially important aspects of cell biology and transformation.This book provides an up-to-date overview of the 6 major viruses that cause human cancers - HPV, HBV, HCV, EBV, KSHV and HTLV-1 - with respect to their molecular biology and epidemiology and to clinical aspects of disease, therapy and prevention. Contributed by over a dozen internationally renowned scientists, the chapters are comprehensively written and illustrated. The book is suitable for advanced students, postdoctoral researchers, scientists and clinicians who wish to understand the mechanisms leading to cellular transformation and oncogenesis by these viruses as a basis for the development of specific therapeutic and antiviral treatments.

Download or read book Feigin and Cherry s Textbook of Pediatric Infectious Diseases E Book written by James Cherry and published by Elsevier Health Sciences. This book was released on 2017-12-29 with total page 2045 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering unparalleled coverage of infectious diseases in children and adolescents, Feigin & Cherry's Textbook of Pediatric Infectious Diseases 8th Edition, continues to provide the information you need on epidemiology, public health, preventive medicine, clinical manifestations, diagnosis, treatment, and much more. This extensively revised edition by Drs. James Cherry, Gail J. Demmler-Harrison, Sheldon L. Kaplan, William J. Steinbach, and Peter J. Hotez, offers a brand-new full-color design, new color images, new guidelines, and new content, reflecting today's more aggressive infectious and resistant strains as well as emerging and re-emerging diseases - Discusses infectious diseases according to organ system, as well as individually by microorganisms, placing emphasis on the clinical manifestations that may be related to the organism causing the disease. - Provides detailed information regarding the best means to establish a diagnosis, explicit recommendations for therapy, and the most appropriate uses of diagnostic imaging. - Features expanded information on infections in the compromised host; immunomodulating agents and their potential use in the treatment of infectious diseases; and Ebola virus. - Contains hundreds of new color images throughout, as well as new guidelines, new resistance epidemiology, and new Global Health Milestones. - Includes new chapters on Zika virus and Guillain-Barré syndrome. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Download or read book The Ohio State University College of Veterinary Medicine Advances in Veterinary Medicine written by Ohio State University. College of Veterinary Medicine and published by . This book was released on 2009 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Human Herpesviruses written by Ann Arvin and published by Cambridge University Press. This book was released on 2007-08-16 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2036 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1982 with total page 980 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Human Retroviruses written by Robert C. Gallo and published by Academic Press. This book was released on 1991-06-28 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents twenty-four tightly focused reviews on the biology, molecular biology, pathology, and epidemiology of the human retroviruses, particularly HIV and HTLV (Types I and II), as well as animal model systems (simian retroviruses, STLV and SIV, and mouse models). Editor Robert C. Gallo is recognized as a co-discoverer of the AIDS virus.

Download or read book Molecular Analysis of Human T cell Leukemia Virus Regulatory and Accessory Proteins written by Ihab H. Younis and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Human T-cell leukemia virus type 1 (HTLV-1) and type 2 (HTLV-2) are closely related pathogenic human retroviruses. Although, they both transform human primary T cells in vitro, in humans, HTLV-1 is the causative agent for ATLL and HAM/TSP, whereas HTLV-2 disease association is less clear. In this dissertation, we report molecular studies regarding the regulation of HTLV replication and its impact on viral persistence in vivo. In Chapter 2, we generate a novel HTLV-1 clone (H1IT) in which the two regulatory proteins, Tax and Rex, have been separated in an attempt to provide a better reagent to study mutants of these proteins in the context of the provirus and analyze their contribution to HTLV-mediated transformation. In vitro data indicates that H1IT is replication competent and is capable of cellular transformation of primary human T-cells. However, H1IT was unable to persist in vivo, emphasizing the importance of temporal and quantitative regulation of Tax RNA to viral replication. In Chapter 3, we report that both HTLV-1 and HTLV-2 have evolved accessory genes whose products are able to restrict viral replication at a post-transcriptional level. The HTLV-1 p30 and the related HTLV-2 p28 proteins inhibit both Tax and Rex by binding to and retaining tax/rex mRNA in the nucleus, thereby inhibiting virion production. In Chapter 4, we show that p28 is recruited to the viral promoter in a Tax-dependent manner. After recruitment to the promoter, p28 or p30 travels with the transcription elongation machinery until its target mRNA is synthesized. Since the above data is consistent with a critical role of these accessory proteins in viral persistence in vivo, in Chapter 5, we used an animal model of HTLV infection to study the specific contribution of p28 on HTLV-2 survival. In this study, all wtHTLV-2 infected rabbits showed persistent infection, whereas those infected with HTLV-2[delta]p28 were able to eliminate the virus as early as 2 weeks, indicating that p28 is critical for early viral infectivity, spread and/or persistence in rabbits. Collectively, data presented within this dissertation support the conclusion that the regulation of HTLV gene expression a complicated but a tightly controlled process.

Download or read book Abstracts of the Annual Meeting of the American Society for Microbiology written by American Society for Microbiology and published by . This book was released on 1991 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nijkamp and Parnham s Principles of Immunopharmacology written by Michael J. Parnham and published by Springer Nature. This book was released on 2019-12-10 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Immunopharmacology provides a unique source of essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The 4th edition of this internationally recognized textbook has been revised to include recent developments, but continues the established format, dealing with four related fields in a single volume, thus obviating the need to refer to several different textbooks. The first section of the book, providing a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts, particularly the role of epigenetics and the latest understanding of cancer immunology. The second section on immunodiagnostics offers a topical description of widely used molecular techniques and a new chapter on imaging techniques. This is followed by a systematic coverage of drugs affecting the immune system, including natural products. This third section contains 15 updated chapters, covering classical immunopharmacological topics such as anti-asthmatic, anti-rheumatic and immunosuppressive drugs, but also deals with antibiotics, plant-derived and dietary agents, with new chapters on monoclonal antibodies, immunotherapy in sepsis and infection, drugs for soft-tissue autoimmunity and cell therapy. The book concludes with a chapter on immunotoxicology and drug safety tests. Aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first three editions. The book is a valuable single reference for undergraduate and graduate medical and biomedical students, postgraduate chemistry and pharmacy students, researchers in chemistry, biochemistry and the pharmaceutical industry and researchers lacking basic immunological knowledge, who want to understand the actions of drugs on the immune system.

Download or read book Immunoneurology written by Michel Chofflon and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: A considerable amount of information has been gathered in the field of immunoneurology over recent years. This knowledge about modifications in the pathways of neuroimmune diseases has enabled the development of new therapies. In this volume leading experts present the state of the art in the field, covering all aspects from basic science to the development of better therapies.

Download or read book Human T Cell Lymphotropic Virus Type I written by Per Höllsberg and published by John Wiley & Sons. This book was released on 1996-12-02 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: HTLV is made up of any of several retroviruses including the retrovirus known as AIDS. Devoted to the rapidly growing field of HTLV, this book explores the many different aspects of the virus.

Download or read book Biological Agricultural Index written by and published by . This book was released on 1995 with total page 3036 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Medical Virology 8 written by Luis M. de la Maza and published by Springer Science & Business Media. This book was released on 1989-10 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of an international symposium in San Francisco, September 1988. The 13 papers consider viruses not only as pathogens, but also as models for research on biological processes in higher organisms and as vehicles for carrying out protective or curative therapies. Topics include new approaches to testing for various viruses, the molecular epidemiology of Epstein-Barr virus, prospects for vaccines, and HIV1/AIDS in terms of statistics of the epidemic and interactions with other viruses. Another 45 papers are represented by one-page abstracts. Annotation copyrighted by Book News, Inc., Portland, OR

Download or read book Viruses and Human Disease written by Ellen G. Strauss and published by Elsevier. This book was released on 2007-09-21 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, the new edition of this groundbreaking text integrates basic virology with pathophysiological conditions to examine the connection between virology and human disease. Most virology textbooks focus on the molecular biology involved without adequate reference to physiology. This text focuses on viruses that infect humans, domestic animals and vertebrates and is based on extensive course notes from James Strauss' virology class at the California Institute of Technology taught for over 30 years. Expertly depicting in color the molecular structure and replication of each virus, it provides an excellent overview for students and professionals interested in viruses as agents of human disease. - Includes over 30% new material - virtually all of the figures and tables have been redrawn to include the latest information and the text has been extensively rewritten to include the most up-to-date information - Includes a new chapter on emerging and reemerging viral diseases such as avian flu, SARS, the spread of West Nile virus across America, and the continuing spread of Nipah virus in Southeast Asia - Further reading sections at the end of each chapter make it easy find key references - World maps depicting the current distribution of existing and newly emerging viruses are also incorporated into the text

Download or read book Cell Cycle Control written by Eishi Noguchi and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of new reviews and protocols from leading experts in cell cycle regulation, Cell Cycle Control: Mechanisms and Protocols, Second Edition presents a comprehensive guide to recent technical and theoretical advancements in the field. Beginning with the overviews of various cell cycle regulations, this title presents the most current protocols and state-of-the-art techniques used to generate latest findings in cell cycle regulation, such as protocols to analyze cell cycle events and molecules. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Cell Cycle Control: Mechanisms and Protocols, Second Edition will be a valuable resource for a wide audience, ranging from the experienced cell cycle researchers looking for new approaches to the junior graduate students giving their first steps in cell cycle research.