Download or read book Gene Therapy written by Mauro Giacca and published by Springer Science & Business Media. This book was released on 2010-11-01 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: I entered the gene therapy field in the mid-1990s, being fascinated by the immense potential of genes as drugs for the treatment of human disease. Since then, I have experienced the ups and downs of this discipline, and tried to contribute with my work and that of my laboratory to the development of innovative approaches to the treatment of cardiovascular disorders. During these years, I have had several opp- tunities to speak on gene therapy at lectures and academic lessons, and have often noticed that the field is very attractive to scientists of all disciplines. However, as yet no comprehensive book on the subject has been published. Indeed, most books in the field are either a collection of gene transfer laboratory protocols or deal with the subject in a rather superficial manner. Hence the idea to write a gene therapy textbook that is broad and comprehensive, but at the same time provides sufficient molecular and clinical detail to be of interest to students, professors, and specialists in the various disciplines that contribute to gene therapy. I have tried to keep the language plain and, whenever possible, non-technical. Since the book is intended to be a textbook in the field of gene therapy in both the basic science and clinical areas, whenever technical descriptions are required, they are provided.

Download or read book Cytopathology of Infectious Diseases written by PANTANOWITZ LIRON and published by Springer Science & Business Media. This book was released on 2011-12-02 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cytopathology of Infectious Diseases is the first book of its kind to focus entirely on the cytopathology of infectious diseases. It contains all of the pertinent information about the cytology of infectious diseases and microorganisms and will serve as an ideal handy reference. This unique volume covers the cytomorphology of various microorganisms and the host reactions they elicit, and also incorporates an update on advances in the field. Newly recognized infections such as the recent discovery of the Merkel Cell Polyomavirus (MCV) are included, as well as the utility of new immunostains (e.g. CM2B4 for MCV) and the role of molecular techniques that assist in the identification, classification and even quantification of microorganisms. Each chapter is succinctly written and concisely referenced with key published articles and resources. The volume includes practical pointers, useful diagnostic criteria, differential diagnoses and potential pitfalls. Many color images of high resolution that illustrate microorganisms (e.g. branching hyphae) and host reactions (e.g. viral cytopathic effect) are included throughout. Relevant tables with diagrams that provide quick reference guides are incorporated. Cytopathology of Infectious Diseases will serve as a valuable reference tool for cytopathologists, anatomical/clinical pathologists, cytotechnologists, pathology residents and cytopathology fellows.

Download or read book Dorland s Dictionary of Medical Acronyms and Abbreviations written by Dorland and published by Elsevier Health Sciences. This book was released on 2015-07-24 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical acronyms and abbreviations offer convenience, but those countless shortcuts can often be confusing. Now a part of the popular Dorland's suite of products, this reference features thousands of terms from across various medical specialties. Its alphabetical arrangement makes for quick reference, and expanded coverage of symbols ensures they are easier to find. Effective communication plays an important role in all medical settings, so turn to this trusted volume for nearly any medical abbreviation you might encounter. - Symbols section makes it easier to locate unusual or seldom-used symbols. - Convenient alphabetical format allows you to find the entry you need more intuitively. - More than 90,000 entries and definitions. - Many new and updated entries including terminology in expanding specialties, such as Nursing; Physical, Occupational, and Speech Therapies; Transcription and Coding; Computer and Technical Fields. - New section on abbreviations to avoid, including Joint Commission abbreviations that are not to be used. - Incorporates updates suggested by the Institute for Safe Medication Practices (ISMP).

Download or read book Pediatric Allergy Asthma and Immunology written by Arnaldo Cantani and published by Springer Science & Business Media. This book was released on 2008-01-23 with total page 1634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Easy to understand and easy to use, this essential book reflects the rapid progress in one of the most intriguing fields of medicine. It offers state-of-the-art information on basic immunology, fetal-neonatal immunology, and many more fascinating areas.

Download or read book Handbook of Atopic Eczema written by Thomas Ruzicka and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: State-of-the-art review on atopic eczema, one of the most common skin diseases today. This multi-authored handbook covers all aspects relevant for physicians from various disciplines.

Download or read book Retinal Vascular Disease written by A.M. Joussen and published by Springer Science & Business Media. This book was released on 2010-03-29 with total page 807 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular diseases of the retina are a major cause of blindness among all age groups. Edited and written by internationally well-known experts, this state-of-the-art comprehensive overview of basic and clinical science will enhance the understanding of retinal vascular disease and help in the evaluation of current and future treatment approaches for the clinician. The well-structured and highly illustrated text is divided into three easy-to-follow sections. This unique textbook-atlas also includes topics which are not currently found in other retinal disease textbooks, such as case reports and clinical follow-ups.

Download or read book Retroviral Proteases written by Lawrence C. Kuo and published by Gulf Professional Publishing. This book was released on 1994-09-22 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods included in this volume apply to the expression and characterization of retroviral proteases and their inhibitor/substrate design.

Download or read book Veterinary Virology written by Frank J. Fenner and published by Academic Press. This book was released on 2014-06-28 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: Veterinary Virology deals with basic biomedical virology and the clinical discipline of infectious diseases. The book discusses the principles of virology as effecting future developments in the search for preventive and management of infectious diseases in animals, whether singly or as a whole herd or flock. Part I explains the principles of animal virology including the structure, composition, classification, nomenclature, cultivation, and assay of viruses. This part also discusses viral genetics, replication, and evolution (including mutation and genetic engineering). The book also reviews the pathogenesis of viruses, host resistance and susceptibility, as well as the mechanisms of persistent infections and tumor induction. Part II deals with viruses found in domestic animals; this part also explains in detail the properties, replication methods, pathogenesis, immunity, diagnosis, and control of some common viruses. The book discusses some other families of viruses of which no members are yet known as to have caused serious or important diseases in animals. Veterinarians, immunologists, virologists, molecular researchers, students, and academicians in the discipline of virology and cellular biology, as well as livestock owners will find this book helpful.

Download or read book Pharmacogenomics written by Julio Licinio and published by John Wiley & Sons. This book was released on 2009-07-30 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work represents the first comprehensive publication in the innovative field of pharmacogenomics, a field which is set to revolutionize pharmaceutical research. In addition to renowned editors, the list of contributors is a "who-is-who" in the field. Broad coverage of all aspects of pharmacogenomics with a full presentation of applications to disease conditions is featured. Anyone involved in pharmaceutical research and drug development needs this book to keep up with this new and revolutionary approach

Download or read book A History of Experimental Virology written by Alfred Grafe and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: By their powers of reason scientists will be able to extract from nature the answers to their questions. From: Critique of Pure Reason, 1781 Immanuel Kant (1724-1804), German Philosopher History is a composite of stories. The history of the biological disciplines has been written by all those who opened the gates of new knowledge by generating ideas and the experiments to support them. Previous authors have attempted various approaches to the history of virology, as is reflected in the numerous books and book-series issuing from the publishing houses. This volume is an attempt at a compre hensive yet compact survey of virology, which has meant penetrating the rigid limits of the separate disciplines of biology in which virologists have worked. Writing this history of experimental virology was really a search for the origins and for vital signposts to portray the wide scope of the knowledge attained thus far. This was done in com plete awareness of the fact that every presentation depends heavily upon the perspective of the observer, and of necessity communi cates only a part of the whole. The present scientific story hopes to recount the most important knowledge achieved during this past century - the first century of the exciting developments in virology.

Download or read book Dictionary of Medical Acronyms and Abbreviations written by Stanley Jablonski and published by Hanley & Belfus. This book was released on 2004-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dictionary lists acronyms and abbreviations occurring with a reasonable frequency in the literature of medicine and the health care professions. Abbreviations and acronyms are given in capital letters, with no punctuation, and with concise definitions. The beginning sections also include symbols, genetic symbols, and the Greek alphabet and symbols.

Download or read book Cancer Immunology and Immunotherapy written by Glenn Dranoff and published by Springer Science & Business Media. This book was released on 2011-04-11 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.

Download or read book The Handbook of Cannabis Therapeutics written by Ethan B. Russo and published by Routledge. This book was released on 2014-05-22 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn the facts behind the pharmacology and pharmacokinetics of controversial cannabis therapeutics The Handbook of Cannabis Therapeutics: From Bench to Bedside sets aside the condemnation and hysteria of society’s view of cannabis to concentrate on the medically sound aspects of cannabis therapeutics. The world’s foremost experts provide a reasoned, thoroughly researched overview of the controversial subject of cannabis, from its history as a medicine through its latest therapeutic uses. The latest studies on the botany, history, biochemistry, pharmacology, toxicology, clinical use for various illnesses such as AIDS, epilepsy, and multiple sclerosis, and side effects of marijuana are all examined and discussed in depth. This comprehensive resource is a compendium of articles from the Journal of Cannabis Therapeutics—with additional contemporary commentary. It presents startling research that explores and supports the medicinal value of cannabis use and its derivatives as a valid therapeutic resource for pain and inflammation, for several illnesses less responsive to other therapies, and even for certain veterinary uses. Cannabinoids such as nabilone, THC, levonantradol, ajulemic acid, dexanabinal, and others are extensively described, with a review of new indications for cannabinoid pharmaceuticals. The book is carefully referenced to encourage your examination of previous studies and provides tables and figures to enhance understanding of information. The Handbook of Cannabis Therapeutics discusses: the uses of cannabis in Arabic, Greek, Roman, and early English medicines absorption rates pharmacokinetics pharmacodynamics separate extracts versus the use of cannabis in its entirety the therapeutic value of the endocannabinoid system cannabinoids and newborn feeding a comparison of smoking versus oral preparations clinical research data on eating cannabis therapeutic uses as appetite stimulant treatments in obstetrics and gynecology medicinal treatments used in Jamaica the use of cannabis in the treatment of multiple sclerosis the benefits versus the adverse side effects of cannabis use The Handbook of Cannabis Therapeutics is a reference work certain to become crucial to physicians, psychologists, researchers, biochemists, graduate students, and interested members of the public.

Download or read book Bioinformatics and Systems Biology written by Frederick Marcus and published by Springer Science & Business Media. This book was released on 2008-07-22 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collaborative research in bioinformatics and systems biology is a key element of modern biology and health research. This book highlights and provides access to many of the methods, environments, results and resources involved, including integral laboratory data generation and experimentation and clinical activities. Collaborative projects embody a research paradigm that connects many of the top scientists, institutions, their resources and research worldwide, resulting in first-class contributions to bioinformatics and systems biology. Central themes include describing processes and results in collaborative research projects using computational biology and providing a guide for researchers to access them. The book is also a practical guide on how science is managed. It shows how collaborative researchers are putting results together in a way accessible to the entire biomedical community.

Download or read book Sexually Transmitted Infections and Sexually Transmitted Diseases written by Gerd Gross and published by Springer Science & Business Media. This book was released on 2011-08-19 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, up-to-date reference book is intended to serve as the standard guide in the field. It covers the epidemiology and etiology of the various sexually transmitted infections and associated diseases, reviews novel diagnostic methods, and discusses in depth both new and established treatment methods. An important part of the book is devoted to prevention and particularly to immunoprevention by vaccination. Related issues such as sexual abuse, psychosocial aspects, and economic and political considerations are also included. The expertise of many worldwide renowned specialists and superb color illustrations make this book a valuable resource for practitioners from a variety of medical disciplines. It has a reader-friendly structure with “core messages” and “take-home pearls”.

Download or read book Modern Alkaloids written by Ernesto Fattorusso and published by John Wiley & Sons. This book was released on 2008-01-08 with total page 689 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents all important aspects of modern alkaloid chemistry, making it the only work of its kind to offer up-to-date and comprehensive coverage. While the first part concentrates on the structure and biology of bioactive alkaloids, the second one analyzes new trends in alkaloid isolation and structure elucidation, as well as in alkaloid synthesis and biosynthesis. A must for biochemists, organic, natural products, and medicinal chemists, as well as pharmacologists, pharmaceutists, and those working in the pharmaceutical industry.

Download or read book Berry Kohn s Operating Room Technique E Book written by Nancymarie Phillips and published by Elsevier Health Sciences. This book was released on 2016-01-28 with total page 1004 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over 50 years, Berry & Kohn’s Operating Room Technique, 13th Edition has been the text of choice for understanding basic surgical principles and techniques. Highly readable, accurate, and comprehensive, it clearly covers the "nuts and bolts" of surgical techniques in a step-by-step format that makes it easy to effectively apply basic principles to clinical practice. Expert author Nancymarie Phillips emphasizes the importance of teamwork throughout, with practical strategies and examples of how cooperation among perioperative caregivers contributes to positive patient care outcomes. With a strong focus on the physiologic, psychologic, and spiritual considerations of perioperative patients, this updated and expanded new edition gives students the knowledge they need to plan and implement comprehensive, individualized care. Detailed information on the fundamentals of perioperative nursing and surgical technology roles enhances your understanding of basic surgical principles and techniques. Emphasis on teamwork among perioperative caregivers encourages cooperation in attaining positive patient care outcomes. In-depth discussions of patients with special needs related to age or health status help you learn how to develop a plan of care tailored to the unique care parameters of all patients. Focus on the physiologic, psychologic, and spiritual considerations of perioperative patients gives you the knowledge you need to plan and implement comprehensive, individualized care. Content on perioperative patient care for both inpatient and ambulatory procedures highlights key considerations for each setting, as well as for individual surgical procedures. Chapter outlines with page numbers, chapter objectives, and key terms and definitions help you quickly find important information and focus your study time. New illustrations reflect new and changing perioperative procedures, and provide you with key safety information like how to maintain a sterile field, gown, and glove. Enhanced TEACH manual and extensive Evolve resources maximize classroom learning. All Evolve materials are highlighted within the text. Step-by-step coverage of the foundations of surgical techniques enables you to effectively apply basic principles to practice. Additional and updated tables and boxes call attention to the most important concepts from the text. References highlight the evidence-based practice approach used throughout the text.