Download or read book Sendai Virus Vector written by Yoshiyuki Nagai and published by Springer Science & Business Media. This book was released on 2014-01-31 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sendai virus (SeV) is not just a mouse pathogen but is evolving into a cutting-edge component of biotechnology. SeV reverse genetics originating from a pure academic need to settle long-held questions in the biology and pathogenicity of nonsegmented negative strand RNA viruses (Mononegavirales) is about to bear the impressive fruit of multipurpose cytoplasmic (non-integrating) RNA vectors. This book brings together in one source the SeV biology revealed by conventional approaches and reverse genetics, the methods to construct the first-generation SeV vector and to generate safer versions, and the applications in medical settings that have left or are about to leave the laboratory bench. The applications, which already are diverse and have high medical impact, include use as vaccine vectors against AIDS and respiratory virus infections, creation of BioKnife to resect malignant tumors, induction of “footprint (transgene) free” pluripotent stem cells, and gene therapy for peripheral arterial disease. These achievements—which are just a few of many examples—were attainable only after rigorously incorporating the rich knowledge of SeV biology that has accumulated during the several decades since the discovery of the virus. Application of SeV vector is certain to expand greatly because of its extremely high performance in transgene expression and its remarkable target cell breadth.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1981 with total page 960 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Comprehensive Virology written by Heinz Fraenkel-Conrat and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and num bering, has probably reached that stage at which relatively few new truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, biochemical cytology, and high resolution microscopy and spectroscopy, the field has experienced a genuine information explosion. Few serious attempts have been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 18 volumes, represents a commitment by a large group of active investigators to analyze, digest, and expostulate on the great mass of data relating to viruses, much of which is now amorphous and disjointed, and scattered throughout a wide literature. In this way, we hope to place the entire field in perspective, and to develop an invalua ble reference and sourcebook for researchers and students at all levels. This series is designed as a continuum that can be entered anywhere, but which also provides a logical progression of developing facts and integrated concepts.
Download or read book The Paramyxoviruses written by David W. Kingsbury and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: What justifies the size of this compendium of reviews on the paramyxoviruses? As intracellular parasites that reproduce with almost complete indifference to nuclear activities, paramyxoviruses have not been providing insights about genes that regulate cellular activities and development, topics that account for much of the excitement in modem biology. For contributions of virus research to those topics, we must look to the retroviruses, which have the propensity to steal developmentally important genes and subvert them to malignant pur poses, and to the nuclear DNA viruses, whose gene expression depends heavily upon cellular transcription machinery, making them exceptionally useful tools for identifying and characterizing components of that machinery. From this perspective, it may appear that purely lytic viruses like the paramyxoviruses are sitting on the sidelines of contemporary biology. But there is plenty of action on the sidelines. Paramyxoviruses remain unconquered, devastating agents of disease. Human deaths attributable to paramyxoviruses worldwide, especially in children, are numbered in the mil lions annually. There are many pathogenic paramyxoviruses and too few effec tive vaccines, and those vaccines (against measles and mumps) are affordable only by relatively affluent nations. Moreover, the paramyxoviruses are intrin sically interesting organisms, presenting the challenge of understanding the self-replication of RNA and many other challenges peculiar to the structures and functions of their proteins, not only as individual entities, but also as they act in concert during virus reproduction and interact with vital functions of the cells they infect and often (but not always) destroy.
Download or read book The Journal of General Virology written by and published by . This book was released on 1982 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Virology Abstracts written by and published by . This book was released on 1987 with total page 1018 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Current Bibliography of Epidemiology written by and published by . This book was released on 1972 with total page 1418 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pesticides Documentation Bulletin written by and published by . This book was released on 1965-11 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Diseases written by Henry L. Foster and published by Academic Press. This book was released on 2014-04-22 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Mouse in Biomedical Research, Volume II: Diseases is a compilation of papers detailing infectious diseases of the mouse. This compilation deals with bacterial, mycotic, viral, protozoal, rickettsial, parasitic, non-neoplastic, and metabolic diseases of the mouse. Several papers describe the different diseases found in the digestive, respiratory, urogenital, integumentary, central nervous, lymphoreticular, musculoskeletal, cardiovascular, and endocrine systems of the mouse. This book lists the possible bacterial infections, as well as other miscellaneous infections such as those caused by aerosols, particles, and the air in the laboratory environment. This text also lists viruses that can affect the mouse such as the lactate dehydrogenase-elevating virus, mouse pox, polyomavirus, and the minute virus. This book describes the process of identification, diagnosis, epidemiology, treatment, control, prevention, and occurrence of these diseases. This text also reviews the diseases that can be transmitted from infected mice to humans, as well as through animal bites and allergic reactions. This book is suitable for researchers, clinical assistants, and scientists dealing with laboratory animals, particularly with mice as test animals. This book can also be helpful for veterinarians and doctors of infectious diseases transferred from animals.
Download or read book Interferon Bibliography from MEDLARS written by and published by . This book was released on 1969 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Interferon and Antiviral Substances Bibliography from MEDLARS written by and published by . This book was released on 1977 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Zoonoses Section B written by George W. Beran and published by CRC Press. This book was released on 2017-12-06 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: This multivolume handbook presents the most authoritative and comprehensive reference work on major zoonoses of the world. The Handbook of Zoonoses covers most diseases communicable to humans, as well as those diseases common to both animals and humans. It identifies animal diseases that are host specific and reviews the effects of various human diseases on animals. Discussions address diseases that remain important public and animal health problems and the techniques that can control and prevent them. The chapters are written by internationally recognized scientists in their respective areas of disease, who work or have worked extensively in the most affected areas of the world. The emphasis for each zoonosis is on the epidemiology of the disease, the clinical syndromes and carrier states in infected animals and humans, and the most current methods for diagnosis and approaches to control. For infectious agents or biologic toxins, which may be transmitted by foods of animal origin, a strong focus is placed on food safety measures. The etiologic and therapeutic aspects of each disease important to epidemiology and control are identified.
Download or read book Fields Virology written by David Mahan Knipe and published by Lippincott Williams & Wilkins. This book was released on 2007 with total page 3116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Accompanying CD-ROM has same title as book.
Download or read book The Mouse in Biomedical Research written by and published by Elsevier. This book was released on 2006-11-30 with total page 773 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diseases, the second volume in the four volume set, The Mouse in Biomedical Research, departs from the first edition, by discussing specific disease causing microorganisms, rather than the format used in the first edition which discussed infectious diseases affecting specific organs and tissues. As such, the volume consists of 26 chapters subdivided into RNA viruses and DNA viruses, as well as bacterial, mycotic, and parasitic infections. These chapters not only provide updates on pathogenesis, epidemiology and prevention of previously recognized murine pathogens, but also include information on newly recognized disease-causing organisms: mouse parvovirus, cilia associated respiratory bacilli and Helicobacter spp. A separate category, consisting of 3 chapters, discusses zoonoses, tumor pathology of genetically engineered mice, and spontaneous diseases in commonly used mouse strains.
Download or read book Laboratory Animal Medicine written by Lynn C. Anderson and published by Elsevier. This book was released on 2015-07-04 with total page 1727 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Animal Medicine, Third Edition, is a fully revised publication from the American College of Laboratory Medicine's acclaimed blue book series. It presents an up-to-date volume that offers the most thorough coverage of the biology, health, and care of laboratory animals. The book is organized by species, with new inclusions of chinchillas, birds, and program and employee management, and is written and edited by known experts in the fields. Users will find gold-standard guidance on the study of laboratory animal science, as well as valuable information that applies across all of the biological and biomedical sciences that work with animals. - Organized by species for in-depth understanding of biology, health, and best care of animals - Features the inclusion of chinchillas, quail, and zebra finches as animal models - Offers guidance on program and employee management - Covers regulations, policies, and laws for laboratory animal management worldwide
Download or read book Infectious Diseases written by Sherwood L. Gorbach and published by Lippincott Williams & Wilkins. This book was released on 2004 with total page 2546 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Third Edition of this definitive reference provides comprehensive guidelines on the diagnosis, treatment, and prevention of every infectious disease seen in current clinical practice. More than 300 world-class practitioners detail the full range of clinical infections, microorganisms, diagnostic tests, and antimicrobial therapies. Coverage includes chapters on surgical infections written by preeminent surgeons and up-to-the-minute information on HIV infection. A comprehensive antimicrobial drugs section includes tables that provide at-a-glance prescribing information. New Third Edition chapters cover bioterrorism, hospital infections, emerging infections, human herpesvirus-8, West Nile virus, food safety, linezolid and quinupristin/dalfopristin, molecular diagnostics, and diagnostic significance of nonspecific laboratory abnormalities.
Download or read book Bibliography of Agriculture written by and published by . This book was released on 1976 with total page 1732 pages. Available in PDF, EPUB and Kindle. Book excerpt:
